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Select item 108495991.

Atypical inflammatory kinase IKBKE phosphorylates and inactivates FoxA1 to promote liver tumorigenesis

Bing Gao, Xueji Wu, Lang Bu, Qiwei Jiang, Lei Wang, Haining Liu, Xiaomei Zhang, Yuanzhong Wu, Xiaoxing Li, Jingting Li, Ying Liang, Lixia Xu, Wei Xie, Jianping Guo

Sci Adv. 2024 Feb 9; 10(6): eadk2285. Published online 2024 Feb 7. doi: 10.1126/sciadv.adk2285

PMCID:: PMC10849599

Abstract Article PDF–5.3M

Select item 105528952.

Lysosome‐dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer

Sherly I. Celada, Guoliang Li, Lindsay J. Celada, Wenfu Lu, Thanigaivelan Kanagasabai, Weiran Feng, Zhen Cao, Nazifa Salsabeel, Ninghui Mao, LaKendria K. Brown, Zaniya A. Mark, Michael G. Izban, Billy R. Ballard, Xinchun Zhou, Samuel E. Adunyah, Robert J. Matusik, Xiaofei Wang, Zhenbang Chen

Mol Oncol. 2023 Oct; 17(10): 2126–2146. Published online 2023 Aug 21. doi: 10.1002/1878-0261.13497

PMCID:: PMC10552895

Abstract Article PDF–3.3M

Select item 105215663.

Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2

Yahong Xu, Yongjie Zhu, Zhenru Wu, Shengfu Li, Mingyang Shao, Qing Tao, Qing Xu, Yuwei Chen, Yuke Shu, Menglin Chen, Yongjie Zhou, Yujun Shi

BMC Cancer. 2023; 23: 906. Published online 2023 Sep 26. doi: 10.1186/s12885-023-11393-1

PMCID:: PMC10521566

Abstract Article PDF–11M

Select item 98805974.

Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation

Kiya W. Govek, Sixing Chen, Paraskevi Sgourdou, Yao Yao, Steven Woodhouse, Tingfang Chen, Marc V. Fuccillo, Douglas J. Epstein, Pablo G. Camara

Cell Rep. Author manuscript; available in PMC 2023 Jan 27.

Published in final edited form as: Cell Rep. 2022 Dec 6; 41(10): 111768. doi: 10.1016/j.celrep.2022.111768

PMCID:: PMC9880597

Abstract Article PDF–2.4M

Select item 94819755.

Understanding the development of oral epithelial organs through single cell transcriptomic analysis

Qianlin Ye, Arshia Bhojwani, Jimmy K. Hu

Development. 2022 Aug 15; 149(16): dev200539. Published online 2022 Aug 17. doi: 10.1242/dev.200539

PMCID:: PMC9481975

Abstract Article

Select item 94465506.

Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathway

Lijun Li, Yibo Wang, Zhongxiang Wang, Deting Xue, Chengxin Dai, Xiang Gao, Jianfei Ma, Kai Hang, Zhijun Pan

Stem Cell Res Ther. 2022; 13: 456. Published online 2022 Sep 5. doi: 10.1186/s13287-022-03133-2

PMCID:: PMC9446550

Abstract Article PDF–8.6M

Select item 93785477.

FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma

Grace Orstad, Gabriela Fort, Timothy J Parnell, Alex Jones, Chris Stubben, Brian Lohman, Katherine L. Gillis, Walter Orellana, Rushmeen Tariq, Olaf Klingbeil, Klaus Kaestner, Christopher R. Vakoc, Benjamin T. Spike, Eric L. Snyder

Dev Cell. Author manuscript; available in PMC 2023 Aug 8.

Published in final edited form as: Dev Cell. 2022 Aug 8; 57(15): 1866–1882.e10. Published online 2022 Jul 13. doi: 10.1016/j.devcel.2022.06.017

PMCID:: PMC9378547

Abstract Article PDF–3.2M

Select item 91332318.

Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes

Nicole Bell, Sanket Bhagat, Shanmugam Muruganandan, Ryunhyung Kim, Kailing Ho, Rachel Pierce, Elena Kozhemyakina, Andrew B. Lassar, Laura Gamer, Vicki Rosen, Andreia M. Ionescu

Bone. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Bone. 2022 Jul; 160: 116418. Published online 2022 Apr 6. doi: 10.1016/j.bone.2022.116418

PMCID:: PMC9133231

Abstract Article PDF–3.8M

Select item 83531649.

The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection

Ching-In Lau, Jasmine Rowell, Diana C. Yanez, Anisha Solanki, Susan Ross, Masahiro Ono, Tessa Crompton

Development. 2021 Aug 1; 148(15): dev199754. Published online 2021 Jul 29. doi: 10.1242/dev.199754

PMCID:: PMC8353164

Abstract Article

Select item 827959110.

FOXA1 overexpression suppresses interferon signaling and immune response in cancer

Yundong He, Liguo Wang, Ting Wei, Yu-Tian Xiao, Haoyue Sheng, Hengchuan Su, Daniel P. Hollern, Xiaoling Zhang, Jian Ma, Simeng Wen, Hongyan Xie, Yuqian Yan, Yunqian Pan, Xiaonan Hou, Xiaojia Tang, Vera J. Suman, Jodi M. Carter, Richard Weinshilboum, Liewei Wang, Krishna R. Kalari, Saravut J. Weroha, Alan H. Bryce, Judy C. Boughey, Haidong Dong, Charles M. Perou, Dingwei Ye, Matthew P. Goetz, Shancheng Ren, Haojie Huang

J Clin Invest. 2021 Jul 15; 131(14): e147025. Published online 2021 Jul 15. doi: 10.1172/JCI147025

PMCID:: PMC8279591

Abstract Article PDF–17M

Select item 825376111.

Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver

Najla AlOgayil, Klara Bauermeister, Jose Hector Galvez, Varun S. Venkatesh, Qinwei Kim-wee Zhuang, Matthew L. Chang, Rachel A. Davey, Jeffrey D. Zajac, Kinuyo Ida, Akihide Kamiya, Teruko Taketo, Guillaume Bourque, Anna K. Naumova

Sci Rep. 2021; 11: 13766. Published online 2021 Jul 2. doi: 10.1038/s41598-021-93216-6

Correction in:: Sci Rep. 2021; 11: 22975.

PMCID:: PMC8253761

Abstract Article PDF–7.9M

Select item 820182812.

Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes

Daiki Kajioka, Kentaro Suzuki, Shoko Matsushita, Shinjiro Hino, Tetsuya Sato, Shuji Takada, Kyoichi Isono, Toru Takeo, Mizuki Kajimoto, Naomi Nakagata, Mitsuyoshi Nakao, Mikita Suyama, Tony DeFalco, Shinichi Miyagawa, Gen Yamada

Proc Natl Acad Sci U S A. 2021 Jun 8; 118(23): e2024067118. Published online 2021 May 31. doi: 10.1073/pnas.2024067118

PMCID:: PMC8201828

Abstract Article PDF–1.9M

Select item 817224113.

Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function

Erin J Golden, Eric D Larson, Lauren A Shechtman, G Devon Trahan, Dany Gaillard, Timothy J Fellin, Jennifer K Scott, Kenneth L Jones, Linda A Barlow

eLife. 2021; 10: e64013. Published online 2021 May 19. doi: 10.7554/eLife.64013

PMCID:: PMC8172241

Abstract Article PDF–6.8M

Select item 817003914.

Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling

Lara López-González, Antonia Alonso, Elena García-Calero, Eduardo de Puelles, Luis Puelles

Front Cell Dev Biol. 2021; 9: 676121. Published online 2021 May 19. doi: 10.3389/fcell.2021.676121

PMCID:: PMC8170039

Abstract Article PDF–7.9M

Select item 812991115.

FoxA-dependent DNA demethylation initiates epigenetic control of cellular stability

Yitzhak Reizel, Ashleigh Morgan, Long Gao, Jonathan Schug, Sarmistha Mukherjee, Meilín M. Fernández García, Greg Donahue, Joseph A. Baur, Kenneth S Zaret, Klaus H Kaestner

Dev Cell. Author manuscript; available in PMC 2022 Mar 8.

Published in final edited form as: Dev Cell. 2021 Mar 8; 56(5): 602–612.e4. Published online 2021 Feb 25. doi: 10.1016/j.devcel.2021.02.005