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Select item 111767821.

Grp78 destabilization of infectious prions is strain-specific and modified by multiple factors including accessory chaperones and pH

Daniel Shoup, Suzette A. Priola

J Biol Chem. 2024 Jun; 300(6): 107346. Published online 2024 May 6. doi: 10.1016/j.jbc.2024.107346

PMCID:: PMC11176782

Abstract Article PDF–1.6M

Select item 111615122.

Protein translation rate determines neocortical neuron fate

Ekaterina Borisova, Andrew G. Newman, Marta Couce Iglesias, Rike Dannenberg, Theres Schaub, Bo Qin, Alexandra Rusanova, Marisa Brockmann, Janina Koch, Marieatou Daniels, Paul Turko, Olaf Jahn, David R. Kaplan, Marta Rosário, Takao Iwawaki, Christian M. T. Spahn, Christian Rosenmund, David Meierhofer, Matthew L. Kraushar, Victor Tarabykin, Mateusz C. Ambrozkiewicz

Nat Commun. 2024; 15: 4879. Published online 2024 Jun 7. doi: 10.1038/s41467-024-49198-w

PMCID:: PMC11161512

Abstract Article PDF–17M

Select item 109360503.

Long noncoding RNA Gm2694 drives depressive-like behaviors in male mice by interacting with GRP78 to disrupt endoplasmic reticulum homeostasis

Hong-Sheng Chen, Ji Wang, Hou-Hong Li, Xiao Wang, Shao-Qi Zhang, Tan Deng, Yu-Ke Li, Ruo-Si Zou, Hua-Jie Wang, Rui Zhu, Wen-Long Xie, Gang Zhao, Fang Wang, Jian-Guo Chen

Sci Adv. 2022 Dec; 8(48): eabn2496. Published online 2022 Dec 2. doi: 10.1126/sciadv.abn2496

PMCID:: PMC10936050

Abstract Article PDF–7.2M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107877915.

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy

Weihui Yan, Shanshan Chen, Ying Wang, Yaying You, Ying Lu, Weipeng Wang, Bo Wu, Jun Du, Shicheng Peng, Wei Cai, Yongtao Xiao

Commun Biol. 2024; 7: 94. Published online 2024 Jan 13. doi: 10.1038/s42003-024-05785-7

PMCID:: PMC10787791

Abstract Article PDF–21M

Select item 107554986.

Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion

Chun-Guang Guo, Rui Sun, Xiao Wang, Ye Yuan, Yan Xu, Shihan Li, Xueting Sun, Jue Wang, Xinli Hu, Tiannan Guo, Xiao-Wei Chen, Rui-Ping Xiao, Xiuqin Zhang

Mol Metab. 2024 Jan; 79: 101847. Published online 2023 Nov 30. doi: 10.1016/j.molmet.2023.101847

PMCID:: PMC10755498

Abstract Article PDF–3.6M

Select item 106702917.

ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment

Jiawen Xiang, Anthony J. Pompetti, Adam P. Faranda, Yan Wang, Samuel G. Novo, David Wan-Cheng Li, Melinda K. Duncan

Cells. 2023 Nov; 12(22): 2636. Published online 2023 Nov 16. doi: 10.3390/cells12222636

PMCID:: PMC10670291

Abstract Article PDF–9.2M

Select item 104936658.

Degradation of NLRP3 by p62‐dependent‐autophagy improves cognitive function in Alzheimer's disease by maintaining the phagocytic function of microglia

Dongyuan Zhang, Yu Zhang, Jirong Pan, Jingjing Cao, Xiuping Sun, Xianglei Li, Ling Zhang, Chuan Qin

CNS Neurosci Ther. 2023 Oct; 29(10): 2826–2842. Published online 2023 Apr 18. doi: 10.1111/cns.14219

PMCID:: PMC10493665

Abstract Article PDF–29M

Select item 104659249.

Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis

Claudia N Spaan, Ruben J de Boer, Wouter L Smit, Jonathan HM van der Meer, Manon van Roest, Jacqueline LM Vermeulen, Pim J Koelink, Marte AJ Becker, Simei Go, Joana Silva, William J Faller, Gijs R van den Brink, Vanesa Muncan, Jarom Heijmans

Life Sci Alliance. 2023 Nov; 6(11): e202301912. Published online 2023 Aug 29. doi: 10.26508/lsa.202301912

PMCID:: PMC10465924

Abstract Article PDF–1.9M

Select item 1029445110.

Disturbance of neuron–microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice

Jingyi Xu, Chunshu Yang, Siyuan Zeng, Xuejiao Wang, Pingting Yang, Ling Qin

J Neuroinflammation. 2023; 20: 150. Published online 2023 Jun 26. doi: 10.1186/s12974-023-02832-8

PMCID:: PMC10294451

Abstract Article PDF–7.5M

Select item 1029010211.

NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation

Isidoro Cobo, Sumit Paliwal, Cristina Bodas, Irene Felipe, Júlia Melià-Alomà, Ariadna Torres, Jaime Martínez-Villarreal, Marina Malumbres, Fernando García, Irene Millán, Natalia del Pozo, Joo-Cheol Park, Ray J. MacDonald, Javier Muñoz, Raúl Méndez, Francisco X. Real

Nat Commun. 2023; 14: 3761. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39291-x

PMCID:: PMC10290102

Abstract Article PDF–3.4M

Select item 1019060712.

The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway

Yankun Shao, Yilin Xu, Huang Di, Xinxiu Shi, Yingying Wang, Hongyu Liu, Lina Song

IET Nanobiotechnol. 2023 May; 17(3): 182–196. Published online 2023 Jan 20. doi: 10.1049/nbt2.12113

PMCID:: PMC10190607

Abstract Article PDF–4.2M

Select item 1004632513.

Immunoexpression Pattern of Autophagy Markers in Developing and Postnatal Kidneys of Dab1^−/−(yotari) Mice

Mirko Maglica, Nela Kelam, Ejazul Haque, Ilija Perutina, Anita Racetin, Natalija Filipović, Yu Katsuyama, Katarina Vukojević

Biomolecules. 2023 Mar; 13(3): 402. Published online 2023 Feb 21. doi: 10.3390/biom13030402

PMCID:: PMC10046325

Abstract Article PDF–72M

Select item 984843114.

The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development

Eui-Seon Lee, Yam Prasad Aryal, Tae-Young Kim, Elina Pokharel, Ji-Youn Kim, Hitoshi Yamamoto, Chang-Hyeon An, Seo-Young An, Jae-Kwang Jung, Youngkyun Lee, Jung-Hong Ha, Wern-Joo Sohn, Jae-Young Kim

Front Physiol. 2022; 13: 1079355. Published online 2023 Jan 4. doi: 10.3389/fphys.2022.1079355

PMCID:: PMC9848431

Abstract Article PDF–4.4M

Select item 976094815.

Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy

Victoria Anne Brentville, Peter Symonds, JiaXin Chua, Anne Skinner, Ian Daniels, Katherine Wendy Cook, Sasa Koncarevic, Roxana Martinez-Pinna, Sabaria Shah, Ruhul Hasan Choudhury, Poonam Vaghela, Daisy Weston, Abdullah Al-Omari, James Davis, Lindy G. Durrant

Front Immunol. 2022; 13: 1066185. Published online 2022 Dec 5. doi: 10.3389/fimmu.2022.1066185

PMCID:: PMC9760948

Abstract Article PDF–2.4M

Select item 974691616.

HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2

Julien Sallais, Chanho Park, Sruthi Alahari, Tyler Porter, Ruizhe Liu, Merve Kurt, Abby Farrell, Martin Post, Isabella Caniggia

JCI Insight. 2022 Dec 8; 7(23): e158908. Published online 2022 Dec 8. doi: 10.1172/jci.insight.158908

PMCID:: PMC9746916

Abstract Article PDF–7.1M

Select item 960672217.

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development

Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener

Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.

Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002

PMCID:: PMC9606722

Abstract Article PDF–6.7M

Select item 960386018.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 958868719.

ER stress transforms random olfactory receptor choice into axon targeting precision

Hani J. Shayya, Jerome K. Kahiapo, Rachel Duffié, Katherine S. Lehmann, Lisa Bashkirova, Kevin Monahan, Ryan P. Dalton, Joanna Gao, Song Jiao, Ira Schieren, Leonardo Belluscio, Stavros Lomvardas

Cell. Author manuscript; available in PMC 2023 Oct 13.

Published in final edited form as: Cell. 2022 Oct 13; 185(21): 3896–3912.e22. Published online 2022 Sep 26. doi: 10.1016/j.cell.2022.08.025

PMCID:: PMC9588687

Abstract Article PDF–3.1M

Select item 955156720.

KRAS protein expression becomes progressively restricted during embryogenesis and in adulthood

Marie-Albane Minati, Mohamad Assi, Maxime Libert, Sabine Cordi, Frédéric Lemaigre, Patrick Jacquemin

Front Cell Dev Biol. 2022; 10: 995013. Published online 2022 Sep 27. doi: 10.3389/fcell.2022.995013

PMCID:: PMC9551567

Abstract Article PDF–5.6M

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