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Select item 101104221.

Hox11-expressing interstitial cells contribute to adult skeletal muscle at homeostasis

Corey G. K. Flynn, Paul R. Van Ginkel, Katharine A. Hubert, Qingyuan Guo, Steven M. Hrycaj, Aubrey E. McDermott, Angelo Madruga, Anna P. Miller, Deneen M. Wellik

Development. 2023 Feb 15; 150(4): dev201026. Published online 2023 Feb 23. doi: 10.1242/dev.201026

PMCID:: PMC10110422

Abstract Article

Select item 99909902.

Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer–Rokitansky–Küster–Hauser syndrome

Ella Thomson, Minh Tran, Gorjana Robevska, Katie Ayers, Jocelyn van der Bergen, Prarthna Gopalakrishnan Bhaskaran, Eric Haan, Silvia Cereghini, Alla Vash-Margita, Miranda Margetts, Alison Hensley, Quan Nguyen, Andrew Sinclair, Peter Koopman, Emanuele Pelosi

Hum Mol Genet. 2023 Mar 15; 32(6): 1032–1047. Published online 2022 Oct 25. doi: 10.1093/hmg/ddac262

PMCID:: PMC9990990

Abstract Article PDF–2.2M

Select item 97147963.

Macrophage TGF-β signaling is critical for wound healing with heterotopic ossification after trauma

Nicole K. Patel, Johanna H. Nunez, Michael Sorkin, Simone Marini, Chase A. Pagani, Amy L. Strong, Charles D. Hwang, Shuli Li, Karthik R. Padmanabhan, Ravi Kumar, Alec C. Bancroft, Joey A. Greenstein, Reagan Nelson, Husain A. Rasheed, Nicholas Livingston, Kaetlin Vasquez, Amanda K. Huber, Benjamin Levi

JCI Insight. 2022 Oct 24; 7(20): e144925. Published online 2022 Oct 24. doi: 10.1172/jci.insight.144925

PMCID:: PMC9714796

Abstract Article PDF–11M

Select item 90658854.

Hoxa11-mediated reduction of cell migration contributes to myeloid sarcoma formation induced by cooperation of MLL/AF10 with activating KRAS mutation in a mouse transplantation model: Hoxa11 in myeloid sarcoma formation

Jen-Fen Fu, Chih-Jen Wen, Tzung-Hai Yen, Lee-Yung Shih

Neoplasia. 2022 Jul; 29: 100802. Published online 2022 Apr 29. doi: 10.1016/j.neo.2022.100802

PMCID:: PMC9065885

Abstract Article PDF–2.2M

Select item 89401775.

Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity

Catarina Catela, Yihan Chen, Yifei Weng, Kailong Wen, Paschalis Kratsios

eLife. 2022; 11: e70766. Published online 2022 Mar 22. doi: 10.7554/eLife.70766

PMCID:: PMC8940177

Abstract Article PDF–6.0M

Select item 87526746.

Breaking constraint of mammalian axial formulae

Gabriel M. Hauswirth, Victoria C. Garside, Lisa S. F. Wong, Heidi Bildsoe, Jan Manent, Yi-Cheng Chang, Christian M. Nefzger, Jaber Firas, Joseph Chen, Fernando J. Rossello, Jose M. Polo, Edwina McGlinn

Nat Commun. 2022; 13: 243. Published online 2022 Jan 11. doi: 10.1038/s41467-021-27335-z

PMCID:: PMC8752674

Abstract Article PDF–4.8M

Select item 84977787.

Tbx4 function during hindlimb development reveals a mechanism that explains the origins of proximal limb defects

Veronique Duboc, Fatima A. Sulaiman, Eleanor Feneck, Anna Kucharska, Donald Bell, Muriel Holder-Espinasse, Malcolm P. O. Logan

Development. 2021 Oct 1; 148(19): dev199580. Published online 2021 Sep 24. doi: 10.1242/dev.199580

PMCID:: PMC8497778

Abstract Article

Select item 83739318.

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

Christopher Chase Bolt, Lucille Lopez-Delisle, Bénédicte Mascrez, Denis Duboule

Nat Commun. 2021; 12: 5013. Published online 2021 Aug 18. doi: 10.1038/s41467-021-25330-y

PMCID:: PMC8373931

Abstract Article PDF–3.1M

Select item 82777369.

Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice

Danielle Rux, Kimberly Helbig, Eiki Koyama, Maurizio Pacifici

Dev Biol. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Dev Biol. 2021 Sep; 477: 49–63. Published online 2021 May 16. doi: 10.1016/j.ydbio.2021.05.007

PMCID:: PMC8277736

Abstract Article PDF–6.7M

Select item 818958110.

Hoxa10 mediates positional memory to govern stem cell function in adult skeletal muscle

Kiyoshi Yoshioka, Hiroshi Nagahisa, Fumihito Miura, Hiromitsu Araki, Yasutomi Kamei, Yasuo Kitajima, Daiki Seko, Jumpei Nogami, Yoshifumi Tsuchiya, Narihiro Okazaki, Akihiko Yonekura, Seigo Ohba, Yoshinori Sumita, Ko Chiba, Kosei Ito, Izumi Asahina, Yoshihiro Ogawa, Takashi Ito, Yasuyuki Ohkawa, Yusuke Ono

Sci Adv. 2021 Jun; 7(24): eabd7924. Published online 2021 Jun 9. doi: 10.1126/sciadv.abd7924

PMCID:: PMC8189581

Abstract Article PDF–7.8M

Select item 817224211.

Translation inhibitory elements from Hoxa3 and Hoxa11 mRNAs use uORFs for translation inhibition

Fatima Alghoul, Schaeffer Laure, Gilbert Eriani, Franck Martin

eLife. 2021; 10: e66369. Published online 2021 Jun 2. doi: 10.7554/eLife.66369

PMCID:: PMC8172242

Abstract Article PDF–3.1M

Select item 770466612.

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster

Yoshiki Higashijima, Nao Nagai, Masamichi Yamamoto, Taro Kitazawa, Yumiko K. Kawamura, Akashi Taguchi, Natsuko Nakada, Masaomi Nangaku, Tetsushi Furukawa, Hiroyuki Aburatani, Hiroki Kurihara, Youichiro Wada, Yasuharu Kanki

Commun Biol. 2020; 3: 725. Published online 2020 Nov 30. doi: 10.1038/s42003-020-01456-5

PMCID:: PMC7704666

Abstract Article PDF–1.3M

Select item 743800413.

Loss of U11 small nuclear RNA in the developing mouse limb results in micromelia

Kyle D. Drake, Christopher Lemoine, Gabriela S. Aquino, Anna M. Vaeth, Rahul N. Kanadia

Development. 2020 Nov 1; 147(21): dev190967. Published online 2020 Aug 14. doi: 10.1242/dev.190967

PMCID:: PMC7438004

Abstract Article

Select item 726966114.

Proximo-distal positional information encoded by an Fgf-regulated gradient of homeodomain transcription factors in the vertebrate limb

Irene Delgado, Alejandra C. López-Delgado, Alberto Roselló-Díez, Giovanna Giovinazzo, Vanessa Cadenas, Laura Fernández-de-Manuel, Fátima Sánchez-Cabo, Matthew J. Anderson, Mark Lewandoski, Miguel Torres

Sci Adv. 2020 Jun; 6(23): eaaz0742. Published online 2020 Jun 3. doi: 10.1126/sciadv.aaz0742

PMCID:: PMC7269661

Abstract Article PDF–5.4M

Select item 725995115.

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, Hiroshi Asahara

eLife. 2020; 9: e53608. Published online 2020 May 29. doi: 10.7554/eLife.53608

PMCID:: PMC7259951

Abstract Article PDF–5.5M

Select item 723742216.

HOX13-dependent chromatin accessibility underlies the transition towards the digit development program

Ines Desanlis, Yacine Kherdjemil, Alexandre Mayran, Yasser Bouklouch, Claudia Gentile, Rushikesh Sheth, Rolf Zeller, Jacques Drouin, Marie Kmita

Nat Commun. 2020; 11: 2491. Published online 2020 May 19. doi: 10.1038/s41467-020-16317-2

PMCID:: PMC7237422

Abstract Article PDF–1.8M

Select item 696949717.

The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13

Maria Félix Bastida, Rocío Pérez-Gómez, Anna Trofka, Jianjian Zhu, Alvaro Rada-Iglesias, Rushikesh Sheth, H. Scott Stadler, Susan Mackem, Marian A. Ros

Proc Natl Acad Sci U S A. 2020 Jan 14; 117(2): 1090–1096. Published online 2020 Jan 2. doi: 10.1073/pnas.1919470117

PMCID:: PMC6969497

Abstract Article PDF–1.1M

Select item 674222618.

Adult bone marrow progenitors become decidual cells and contribute to embryo implantation and pregnancy

Reshef Tal, Shafiq Shaikh, Pallavi Pallavi, Aya Tal, Francesc López-Giráldez, Fang Lyu, Yuan-Yuan Fang, Shruti Chinchanikar, Ying Liu, Harvey J. Kliman, Myles Alderman, III, Nicola Pluchino, Jehanzeb Kayani, Ramanaiah Mamillapalli, Diane S. Krause, Hugh S. Taylor

PLoS Biol. 2019 Sep; 17(9): e3000421. Published online 2019 Sep 12. doi: 10.1371/journal.pbio.3000421

PMCID:: PMC6742226

Abstract Article PDF–6.5M

Select item 667936719.

Bone morphology is regulated modularly by global and regional genetic programs

Shai Eyal, Shiri Kult, Sarah Rubin, Sharon Krief, Neta Felsenthal, Kyriel M. Pineault, Dena Leshkowitz, Tomer-Meir Salame, Yoseph Addadi, Deneen M. Wellik, Elazar Zelzer

Development. 2019 Jul 15; 146(14): dev167882. Published online 2019 Jul 26. doi: 10.1242/dev.167882