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Select item 114678111.

The FAcilitates Chromatin Transcription complex regulates the ratio of glycolysis to oxidative phosphorylation in neural stem cells

Yuhan Lou, Litao Wu, Wanlin Cai, Huan Deng, Rong Sang, Shanshan Xie, Xiao Xu, Xin Yuan, Cheng Wu, Man Xu, Wanzhong Ge, Yongmei Xi, Xiaohang Yang

J Mol Cell Biol. 2024 Apr; 16(4): mjae017. Published online 2024 May 8. doi: 10.1093/jmcb/mjae017

PMCID:: PMC11467811

Abstract Article PDF–1.9M

Select item 113121022.

Dysfunction of Mitochondrial Dynamics Induces Endocytosis Defect and Cell Damage in Drosophila Nephrocytes

Jun-yi Zhu, Jianli Duan, Joyce van de Leemput, Zhe Han

Cells. 2024 Aug; 13(15): 1253. Published online 2024 Jul 25. doi: 10.3390/cells13151253

PMCID:: PMC11312102

Abstract Article PDF–9.1M

Select item 111928393.

Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models

Wing Hei Au, Leonor Miller-Fleming, Alvaro Sanchez-Martinez, James AK Lee, Madeleine J Twyning, Hiran A Prag, Laura Raik, Scott P Allen, Pamela J Shaw, Laura Ferraiuolo, Heather Mortiboys, Alexander J Whitworth

Life Sci Alliance. 2024 Sep; 7(9): e202402853. Published online 2024 Jun 21. doi: 10.26508/lsa.202402853

PMCID:: PMC11192839

Abstract Article PDF–3.3M

Select item 111689354.

Senescent glia link mitochondrial dysfunction and lipid accumulation

China N. Byrns, Alexandra E. Perlegos, Karl N. Miller, Zhecheng Jin, Faith R. Carranza, Palak Manchandra, Connor H. Beveridge, Caitlin E. Randolph, V. Sai Chaluvadi, Shirley L. Zhang, Ananth R. Srinivasan, F. C. Bennett, Amita Sehgal, Peter D. Adams, Gaurav Chopra, Nancy M. Bonini

Nature. 2024; 630(8016): 475–483. Published online 2024 Jun 5. doi: 10.1038/s41586-024-07516-8

Correction in:: Nature. 2024; 632(8026): E8.

PMCID:: PMC11168935

Abstract Article PDF–17M

Select item 111132685.

Restricting bioenergetic efficiency enhances longevity and mitochondrial redox capacity in Drosophila melanogaster

Analisa L. Taylor, Olga Dubuisson, Pritika Pandey, Elizabeth R. M. Zunica, Bolormaa Vandanmagsar, Wagner S. Dantas, Alyssa Johnson, Christopher L. Axelrod, John P. Kirwan

Aging Cell. 2024 May; 23(5): e14107. Published online 2024 Feb 11. doi: 10.1111/acel.14107

PMCID:: PMC11113268

Abstract Article PDF–655K

Select item 110723326.

Fly for ALS: Drosophila modeling on the route to amyotrophic lateral sclerosis modifiers

Francesco Liguori, Susanna Amadio, Cinzia Volonté

Cell Mol Life Sci. 2021 Sep; 78(17-18): 6143–6160. Published online 2021 Jul 28. doi: 10.1007/s00018-021-03905-8

PMCID:: PMC11072332

Abstract Article PDF–1.2M

Select item 110264137.

Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila

Jenny Zhe Liao, Hyung-lok Chung, Claire Shih, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C. Marcogliese, Katherine Sew, Hugo J. Bellen, Esther M. Verheyen

Nat Commun. 2024; 15: 3326. Published online 2024 Apr 18. doi: 10.1038/s41467-024-47623-8

PMCID:: PMC11026413

Abstract Article PDF–18M

Select item 110149928.

Mitochondrial fusion and altered beta-oxidation drive muscle wasting in a Drosophila cachexia model

Callum Dark, Nashia Ali, Sofya Golenkina, Vaibhav Dhyani, Ronnie Blazev, Benjamin L Parker, Kate T Murphy, Gordon S Lynch, Tarosi Senapati, S Sean Millard, Sarah M Judge, Andrew R Judge, Lopamudra Giri, Sarah M Russell, Louise Y Cheng

EMBO Rep. 2024 Apr; 25(4): 1835–1858. Published online 2024 Mar 1. doi: 10.1038/s44319-024-00102-z

PMCID:: PMC11014992

Abstract Article PDF–6.2M

Select item 110123519.

Mitochondrial Differentiation during Spermatogenesis: Lessons from Drosophila melanogaster

Viktor Vedelek, Ferenc Jankovics, János Zádori, Rita Sinka

Int J Mol Sci. 2024 Apr; 25(7): 3980. Published online 2024 Apr 3. doi: 10.3390/ijms25073980

PMCID:: PMC11012351

Abstract Article PDF–7.4M

Select item 1100158610.

A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis

Paula R. Haynes, Elana S. Pyfrom, Yongjun Li, Carly Stein, Vishnu Anand Cuddapah, Jack A. Jacobs, Zhifeng Yue, Amita Sehgal

Nat Neurosci. 2024; 27(4): 666–678. Published online 2024 Feb 15. doi: 10.1038/s41593-023-01568-1

PMCID:: PMC11001586

Abstract Article PDF–5.6M

Select item 1094257611.

Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

Chhavi Sood, Md Ausrafuggaman Nahid, Kendall R Branham, Matt Pahl, Susan E Doyle, Sarah E Siegrist

eLife. 2024; 12: RP88565. Published online 2024 Feb 23. doi: 10.7554/eLife.88565

PMCID:: PMC10942576

Abstract Article PDF–7.0M

Select item 1084051412.

COPI-regulated mitochondria-ER contact site formation maintains axonal integrity

Daniel C. Maddison, Bilal Malik, Leonardo Amadio, Dana M. Bis-Brewer, Stephan Züchner, Owen M. Peters, Gaynor A. Smith

Cell Rep. 2023 Aug 29; 42(8): 112883. Published online 2023 Jul 26. doi: 10.1016/j.celrep.2023.112883

PMCID:: PMC10840514

Abstract Article

Select item 1045058013.

Milton assembles large mitochondrial clusters, mitoballs, to sustain spermatogenesis

Andy Y. Z. Li, Ying Di, Sumaera Rathore, Ason C.-Y. Chiang, Jan Jezek, Hansong Ma

Proc Natl Acad Sci U S A. 2023 Aug 22; 120(34): e2306073120. Published online 2023 Aug 14. doi: 10.1073/pnas.2306073120

PMCID:: PMC10450580

Abstract Article PDF–8.2M

Select item 1044453814.

A Novel Interaction between MFN2/Marf and MARK4/PAR-1 Is Implicated in Synaptic Defects and Mitochondrial Dysfunction

Yeongmi Cheon, Sunggyu Yoon, Jae-Hyuk Lee, Kiyoung Kim, Hyung-Jun Kim, Sung Wook Hong, Ye-Rang Yun, Jiwon Shim, Sung-Hak Kim, Bingwei Lu, Mihye Lee, Seongsoo Lee

eNeuro. 2023 Aug; 10(8): ENEURO.0409-22.2023. Prepublished online 2023 Aug 7. Published online 2023 Aug 14. doi: 10.1523/ENEURO.0409-22.2023

PMCID:: PMC10444538

Abstract Article PDF–2.9M

Select item 1024744815.

“Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1”

Y Nemtsova, BL Steinert, KA Wharton

Mol Cell Neurosci. Author manuscript; available in PMC 2023 Jun 8.

Published in final edited form as: Mol Cell Neurosci. 2023 Jun; 125: 103834. Published online 2023 Mar 1. doi: 10.1016/j.mcn.2023.103834

PMCID:: PMC10247448

Abstract Article PDF–2.3M

Select item 1016254516.

Bendless is essential for PINK1-Park mediated Mitofusin degradation under mitochondrial stress caused by loss of LRPPRC

Rajit Narayanan Cheramangalam, Tarana Anand, Priyanka Pandey, Deepa Balasubramanian, Reshmi Varghese, Neha Singhal, Sonal Nagarkar Jaiswal, Manish Jaiswal

PLoS Genet. 2023 Apr; 19(4): e1010493. Published online 2023 Apr 25. doi: 10.1371/journal.pgen.1010493

PMCID:: PMC10162545

Abstract Article PDF–7.7M

Select item 1015096317.

Insights from Drosophila on Aβ- and tau-induced mitochondrial dysfunction: mechanisms and tools

Vanlalrinchhani Varte, Jeremy W. Munkelwitz, Diego E. Rincon-Limas

Front Neurosci. 2023; 17: 1184080. Published online 2023 Apr 17. doi: 10.3389/fnins.2023.1184080

PMCID:: PMC10150963

Abstract Article PDF–3.9M

Select item 1013664518.

USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons

Sofia Mauri, Greta Bernardo, Aitor Martinez, Mariavittoria Favaro, Marta Trevisan, Gael Cobraiville, Marianne Fillet, Federico Caicci, Alexander J. Whitworth, Elena Ziviani

Cells. 2023 Apr; 12(8): 1143. Published online 2023 Apr 13. doi: 10.3390/cells12081143