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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 79387702.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 64178553.

Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal

Thomas W. Gould, Bertha Dominguez, Fred de Winter, Gene W. Yeo, Patrick Liu, Balaji Sundararaman, Thomas Stark, Anthony Vu, Jay L. Degen, Weichun Lin, Kuo-Fen Lee

PLoS Genet. 2019 Mar; 15(3): e1007948. Published online 2019 Mar 14. doi: 10.1371/journal.pgen.1007948

PMCID:: PMC6417855

Abstract Article PDF–4.1M

Select item 58211884.

VKOR paralog VKORC1L1 supports vitamin K–dependent protein carboxylation in vivo

Julie Lacombe, Mark A. Rishavy, Kathleen L. Berkner, Mathieu Ferron

JCI Insight. 2018 Jan 11; 3(1): e96501. Published online 2018 Jan 11. doi: 10.1172/jci.insight.96501

PMCID:: PMC5821188

Abstract Article PDF–2.7M

Select item 52958215.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 42694736.

Severe deficiency of coagulation Factor VII results in spontaneous cardiac fibrosis in mice

H Xu, F Noria, MJ Sandoval-Cooper, H Menchen, DL Donahue, VA Ploplis, FJ Castellino

J Pathol. Author manuscript; available in PMC 2014 Dec 17.

Published in final edited form as: J Pathol. 2009 Feb; 217(3): 362–371. doi: 10.1002/path.2454

PMCID:: PMC4269473

Abstract Article PDF–750K

Select item 40855787.

Factor VIIa binding to endothelial cell protein C receptor protects vascular barrier integrity in vivo

J. SUNDARAM, S. KESHAVA, R. GOPALAKRISHNAN, C. T. ESMON, U. R. PENDURTHI, L . V. M. RAO

J Thromb Haemost. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: J Thromb Haemost. 2014 May; 12(5): 690–700. doi: 10.1111/jth.12532

PMCID:: PMC4085578

Abstract Article PDF–1.9M

Select item 39649558.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 38835929.

Factor VIIa binding to endothelial cell protein C receptor: Differences between mouse and human systems

Prosenjit Sen, Curtis A. Clark, Ramakrishnan Gopalakrishnan, Ulla Hedner, Charles T. Esmon, Usha R. Pendurthi, L. Vijaya Mohan Rao

Thromb Haemost. Author manuscript; available in PMC 2014 Jan 7.

Published in final edited form as: Thromb Haemost. 2012 May; 107(5): 10.1160/TH11-09-0672. Published online 2012 Feb 28. doi: 10.1160/TH11-09-0672

PMCID:: PMC3883592

Abstract Article PDF–3.7M

Select item 359184910.

A CpG Mutational Hotspot in a ONECUT Binding Site Accounts for the Prevalent Variant of Hemophilia B Leyden

Alister P.W. Funnell, Michael D. Wilson, Benoit Ballester, Ka Sin Mak, Jon Burdach, Natisha Magan, Richard C.M. Pearson, Frederic P. Lemaigre, Kathryn M. Stowell, Duncan T. Odom, Paul Flicek, Merlin Crossley

Am J Hum Genet. 2013 Mar 7; 92(3): 460–467. doi: 10.1016/j.ajhg.2013.02.003

PMCID:: PMC3591849

Abstract Article PDF–737K

Select item 352883611.

Endothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa

C A Clark, R Vatsyayan, U Hedner, C T Esmon, U R Pendurthi, L V M Rao

J Thromb Haemost. 2012 Nov; 10(11): 2383–2391. doi: 10.1111/j.1538-7836.2012.04917.x

PMCID:: PMC3528836

Abstract Article PDF–499K

Select item 327172012.

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage

Christopher Binny, Jenny McIntosh, Marco Della Peruta, Hanna Kymalainen, Edward G. D. Tuddenham, Suzanne M. K. Buckley, Simon N. Waddington, John H. McVey, Yunyu Spence, Christopher L. Morton, Adrian J. Thrasher, John T. Gray, Francis J. Castellino, Alice F. Tarantal, Andrew M. Davidoff, Amit C. Nathwani

Blood. 2012 Jan 26; 119(4): 957–966. Prepublished online 2011 Dec 1. doi: 10.1182/blood-2011-09-377630

PMCID:: PMC3271720

Abstract Article

Select item 325886813.

Mechanism of the Ca²⁺-induced Enhancement of the Intrinsic Factor VIIa Activity

Jais R. Bjelke, Ole H. Olsen, Michel Fodje, L. Anders Svensson, Susanne Bang, Gert Bolt, Birthe B. Kragelund, Egon Persson

J Biol Chem. 2008 Sep 19; 283(38): 25863–25870. doi: 10.1074/jbc.M800841200

PMCID:: PMC3258868

Abstract Article PDF–428K

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 308752715.

Catalytic domain modification and viral gene delivery of activated factor VII confers hemostasis at reduced expression levels and vector doses in vivo

Paris Margaritis, Elise Roy, Armida Faella, Harre D. Downey, Lacramioara Ivanciu, Giulia Pavani, Shangzhen Zhou, Ralph M. Bunte, Katherine A. High

Blood. 2011 Apr 14; 117(15): 3974–3982. Prepublished online 2011 Feb 16. doi: 10.1182/blood-2010-09-309732

Correction in:: Blood. 2012 May 10; 119(19): 4577.

PMCID:: PMC3087527

Abstract Article

Select item 302253416.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582