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Items: 1 to 20 of 29

1.
USP25 attenuates anti-GBM nephritis in mice by negative feedback regulation of Th17 cell differentiation
Ranran Xu, Fei Huang, Qingquan Liu, Yongman Lv, Liu Hu, Qian Zhang
Ren Fail. 2024; 46(1): 2338932. Published online 2024 Apr 14. doi: 10.1080/0886022X.2024.2338932
PMCID:
PMC11018034
AbstractArticlePDF–3.1M
2.
Expression of USP25 associates with fibrosis, inflammation and metabolism changes in IgG4-related disease
Panpan Jiang, Yukai Jing, Siyu Zhao, Caini Lan, Lu Yang, Xin Dai, Li Luo, Shaozhe Cai, Yingzi Zhu, Heather Miller, Juan Lai, Xin Zhang, Xiaochao Zhao, Yonggui Wu, Jingzhi Yang, Wen Zhang, Fei Guan, Bo Zhong, Hisanori Umehara, Jiahui Lei, Lingli Dong, Chaohong Liu
Nat Commun. 2024; 15: 2627. Published online 2024 Mar 23. doi: 10.1038/s41467-024-45977-7
PMCID:
PMC10960850
AbstractArticlePDF–11M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2
Zhongding Li, Baohua Liu, Kate Lykke Lambertsen, Bettina Hjelm Clausen, Zhenhu Zhu, Xue Du, Yanqi Xu, Frantz Rom Poulsen, Bo Halle, Christian Bonde, Meng Chen, Xue Wang, Dirk Schlüter, Jingyong Huang, Ari Waisman, Weihong Song, Xu Wang
Adv Sci (Weinh) 2023 Oct; 10(28): 2301641. Published online 2023 Aug 16. doi: 10.1002/advs.202301641
PMCID:
PMC10558664
AbstractArticlePDF–5.7M
5.
USP25 regulates KEAP1-NRF2 anti-oxidation axis and its inactivation protects acetaminophen-induced liver injury in male mice
Changzhou Cai, Huailu Ma, Jin Peng, Xiang Shen, Xinghua Zhen, Chaohui Yu, Pumin Zhang, Feng Ji, Jiewei Wang
Nat Commun. 2023; 14: 3648. Published online 2023 Jun 20. doi: 10.1038/s41467-023-39412-6
PMCID:
PMC10282087
AbstractArticlePDF–2.8M
6.
Downregulation of deubiquitinating enzyme USP25 promotes the development of allergic rhinitis by enhancing TSLP signaling in the nasal epithelium
Wenchuan Chang, Hao Lv, Lu Tan, Ziang Gao, Peiqiang Liu, Danxue Qin, Wei Zhang, Yu Xu
Mol Med Rep. 2022 Nov; 26(5): 347. Published online 2022 Sep 28. doi: 10.3892/mmr.2022.12863
PMCID:
PMC9551407
AbstractArticlePDF–7.1M
7.
USP25 Deficiency Exacerbates Acute Pancreatitis via Up-Regulating TBK1–NF-κB Signaling in Macrophages
Xin Liu, Wu Luo, Jiahao Chen, Chenghong Hu, Rumbidzai N. Mutsinze, Xu Wang, Yanmei Zhang, Lijiang Huang, Wei Zuo, Guang Liang, Yi Wang
Cell Mol Gastroenterol Hepatol. 2022; 14(5): 1103–1122. Published online 2022 Aug 4. doi: 10.1016/j.jcmgh.2022.07.013
PMCID:
PMC9490099
AbstractArticlePDF–8.4M
8.
USP25 inhibition ameliorates Alzheimer’s pathology through the regulation of APP processing and Aβ generation
Qiuyang Zheng, Beibei Song, Guilin Li, Fang Cai, Meiling Wu, Yingjun Zhao, LuLin Jiang, Tiantian Guo, Mingyu Shen, Huan Hou, Ying Zhou, Yini Zhao, Anjie Di, Lishan Zhang, Fanwei Zeng, Xiu-Fang Zhang, Hong Luo, Xian Zhang, Hongfeng Zhang, Zhiping Zeng, Timothy Y. Huang, Chen Dong, Hong Qing, Yun Zhang, Qing Zhang, Xu Wang, Yili Wu, Huaxi Xu, Weihong Song, Xin Wang
J Clin Invest. 2022 Mar 1; 132(5): e152170. Published online 2022 Mar 1. doi: 10.1172/JCI152170
PMCID:
PMC8884900
AbstractArticlePDF–2.5M
9.
Ubiquitin-Specific Protease 25 Aggravates Acute Pancreatitis and Acute Pancreatitis-Related Multiple Organ Injury by Destroying Tight Junctions Through Activation of The STAT3 Pathway
Zhengru Liu, Mingming Qi, Shan Tian, Qian Yang, Jian Liu, Siwei Wang, Mengyao Ji, Rong Yu, Suqi Zeng, Jinting Li, Yuping Wei, Weiguo Dong
Front Cell Dev Biol. 2021; 9: 806850. Published online 2022 Jan 13. doi: 10.3389/fcell.2021.806850
PMCID:
PMC8793747
AbstractArticlePDF–7.0M
10.
USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN
Yue Gao, Jiao Chen, Rui Ji, Jinli Ding, Yan Zhang, Jing Yang
Front Cell Dev Biol. 2021; 9: 779718. Published online 2021 Nov 4. doi: 10.3389/fcell.2021.779718
PMCID:
PMC8599287
AbstractArticlePDF–15M
11.
Trisomy 21–induced dysregulation of microglial homeostasis in Alzheimer’s brains is mediated by USP25
Qiuyang Zheng, Guilin Li, Shihua Wang, Ying Zhou, Ke Liu, Yue Gao, Yulin Zhou, Liangkai Zheng, Lin Zhu, Qingfang Deng, Meiling Wu, Anjie Di, Lishan Zhang, Yingjun Zhao, Hongfeng Zhang, Hao Sun, Chen Dong, Huaxi Xu, Xin Wang
Sci Adv. 2021 Jan; 7(1): eabe1340. Published online 2021 Jan 1. doi: 10.1126/sciadv.abe1340
PMCID:
PMC7775784
AbstractArticlePDF–6.2M
12.
The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes
Jessica B. A. Sadler, Christopher A. Lamb, Cassie R. Welburn, Iain S. Adamson, Dimitrios Kioumourtzoglou, Nai-Wen Chi, Gwyn W. Gould, Nia J. Bryant
Sci Rep. 2019; 9: 4710. Published online 2019 Mar 18. doi: 10.1038/s41598-019-40596-5
PMCID:
PMC6423145
AbstractArticlePDF–1.4M
13.
Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes
Estifanos N. Habtemichael, Don T. Li, Abel Alcázar-Román, Xavier O. Westergaard, Muyi Li, Max C. Petersen, Hanbing Li, Stephen G. DeVries, Eric Li, Omar Julca-Zevallos, Joseph S. Wolenski, Jonathan S. Bogan
J Biol Chem. 2018 Jul 6; 293(27): 10466–10486. Published online 2018 May 17. doi: 10.1074/jbc.RA118.003021
PMCID:
PMC6036200
AbstractArticlePDF–4.2M
14.
Ubiquitin-Specific Protease 25 Regulates TLR4-Dependent Innate Immune Responses Through Deubiquitination of the Adaptor Protein TRAF3
Bo Zhong, Xikui Liu, Xiaohu Wang, Xindong Liu, Hongxiu Li, Bryant G. Darnay, Xin Lin, Shao-Cong Sun, Chen Dong
Sci Signal. Author manuscript; available in PMC 2018 Jan 11.
Published in final edited form as: Sci Signal. 2013 May 14; 6(275): ra35. Published online 2013 May 14. doi: 10.1126/scisignal.2003708
PMCID:
PMC5763475
AbstractArticlePDF–1.5M
15.
The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene
Yujie Ren, Yin Zhao, Dandan Lin, Ximing Xu, Qiyun Zhu, Jing Yao, Hong-Bing Shu, Bo Zhong
J Biol Chem. 2016 Jun 17; 291(25): 13206–13215. Published online 2016 Apr 27. doi: 10.1074/jbc.M116.718080
PMCID:
PMC4933234
AbstractArticlePDF–3.7M
16.
Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling
Akhee S. Jahan, Maxime Lestra, Lee Kim Swee, Ying Fan, Mart M. Lamers, Fikadu G. Tafesse, Christopher S. Theile, Eric Spooner, Roberto Bruzzone, Hidde L. Ploegh, Sumana Sanyal
Proc Natl Acad Sci U S A. 2016 Feb 9; 113(6): E705–E714. Published online 2016 Jan 25. doi: 10.1073/pnas.1521763113
PMCID:
PMC4760780
AbstractArticlePDF–1.4M
17.
Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6
Dandan Lin, Man Zhang, Meng-Xin Zhang, Yujie Ren, Jie Jin, Quanyi Zhao, Zishu Pan, Min Wu, Hong-Bing Shu, Chen Dong, Bo Zhong
Proc Natl Acad Sci U S A. 2015 Sep 8; 112(36): 11324–11329. Published online 2015 Aug 24. doi: 10.1073/pnas.1509968112
Correction in:
Proc Natl Acad Sci U S A. 2015 Oct 27; 112(43): E5901.
Correction in:
Proc Natl Acad Sci U S A. 2020 Aug 25; 117(34): 20970–20971.
PMCID:
PMC4568686
AbstractArticlePDF–1.2M
18.
Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling
Anthony J. Valente, Tadashi Yoshida, Robert A. Clark, Patrice Delafontaine, Ulrich Siebenlist, Bysani Chandrasekar
Free Radic Biol Med. Author manuscript; available in PMC 2014 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2013 Jul; 60: 125–135. Published online 2013 Feb 20. doi: 10.1016/j.freeradbiomed.2013.02.012
PMCID:
PMC3714806
AbstractArticlePDF–3.0M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Negative regulation of IL-17-mediated signaling and inflammation by ubiquitin-specific protease 25
Bo Zhong, Xikui Liu, Xiaohu Wang, Seon Hee Chang, Xindong Liu, Aibo Wang, Joseph M. Reynolds, Chen Dong
Nat Immunol. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Nat Immunol. 2012 Nov; 13(11): 1110–1117. Published online 2012 Oct 7. doi: 10.1038/ni.2427
PMCID:
PMC3477275
AbstractArticlePDF–2.3M

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