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Items: 1 to 20 of 47

1.
Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis
Zhenlei Zhang, Yufan Wu, Jinrong Fu, Xiujie Yu, Yang Su, Shikai Jia, Huili Cheng, Yan Shen, Xianghui He, Kai Ren, Xiangqian Zheng, Haixia Guan, Feng Rao, Li Zhao
Nat Commun. 2024; 15: 4108. Published online 2024 May 15. doi: 10.1038/s41467-024-48173-9
Correction in:
Nat Commun. 2024; 15: 4936.
PMCID:
PMC11096176
AbstractArticlePDF–5.7M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Borealin/CDCA8 deficiency alters thyroid development and results in papillary tumor-like structures
Hortense Didier-Mathon, Athanasia Stoupa, Dulanjalee Kariyawasam, Sonny Yde, Beatrix Cochant-Priollet, Lionel Groussin, Frédéric Sébag, Nicolas Cagnard, Patrick Nitschke, Dominique Luton, Michel Polak, Aurore Carré
Front Endocrinol (Lausanne) 2023; 14: 1286747. Published online 2023 Oct 27. doi: 10.3389/fendo.2023.1286747
PMCID:
PMC10641986
AbstractArticlePDF–20M
4.
Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland
Xiaohan Zhang, Crystal Young, Xiao-Hui Liao, Samuel Refetoff, Mauricio Torres, Yaron Tomer, Mihaela Stefan-Lifshitz, Hao Zhang, Dennis Larkin, Deyu Fang, Ling Qi, Peter Arvan
JCI Insight. 2023 Jun 22; 8(12): e169937. Published online 2023 Jun 22. doi: 10.1172/jci.insight.169937
PMCID:
PMC10371246
AbstractArticlePDF–18M
5.
Maintaining the thyroid gland in mutant thyroglobulin–induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood
Xiaohan Zhang, Bhoomanyu Malik, Crystal Young, Hao Zhang, Dennis Larkin, Xiao-Hui Liao, Samuel Refetoff, Ming Liu, Peter Arvan
J Biol Chem. 2022 Jul; 298(7): 102066. Published online 2022 May 23. doi: 10.1016/j.jbc.2022.102066
PMCID:
PMC9213252
AbstractArticlePDF–3.1M
6.
Germline saturation mutagenesis induces skeletal phenotypes in mice
Jonathan J Rios, Kristin Denton, Jamie Russell, Julia Kozlitina, Carlos R Ferreira, Amy F Lewanda, Joshua E Mayfield, Eva Moresco, Sara Ludwig, Miao Tang, Xiaohong Li, Stephen Lyon, Anas Khanshour, Nandina Paria, Aysha Khalid, Yang Li, Xudong Xie, Jian Q Feng, Qian Xu, Yongbo Lu, Robert E Hammer, Carol A Wise, Bruce Beutler
J Bone Miner Res. Author manuscript; available in PMC 2022 Aug 1.
Published in final edited form as: J Bone Miner Res. 2021 Aug; 36(8): 1548–1565. Published online 2021 May 10. doi: 10.1002/jbmr.4323
PMCID:
PMC8862308
AbstractArticlePDF–2.5M
7.
Asynchrony of Apical Polarization, Luminogenesis, and Functional Differentiation in the Developing Thyroid Gland
Ellen Johansson, Shawn Liang, Carmen Moccia, Therese Carlsson, Daniel Andersson, Henrik Fagman, Mikael Nilsson
Front Endocrinol (Lausanne) 2021; 12: 760541. Published online 2021 Dec 17. doi: 10.3389/fendo.2021.760541
PMCID:
PMC8719337
AbstractArticlePDF–14M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Thyrocyte cell survival and adaptation to chronic endoplasmic reticulum stress due to misfolded thyroglobulin
Yoshiaki Morishita, Omer Kabil, Kelly Z. Young, Aaron P. Kellogg, Amy Chang, Peter Arvan
J Biol Chem. 2020 May 15; 295(20): 6876–6887. Published online 2020 Apr 2. doi: 10.1074/jbc.RA120.012656
PMCID:
PMC7242714
AbstractArticlePDF–2.6M
10.
Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice
Raffaele Gerlini, Elena Amendola, Andrea Conte, Valeria Valente, Mara Tornincasa, Sara Carmela Credendino, Francesca Cammarota, Chiara Gentile, Luigi Di Guida, Simona Paladino, Gabriella De Vita, Alfredo Fusco, Giovanna Maria Pierantoni
Cell Death Dis. 2019 Oct; 10(10): 747. Published online 2019 Oct 3. doi: 10.1038/s41419-019-1975-5
PMCID:
PMC6776533
AbstractArticlePDF–5.8M
11.
Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner
Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler
J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.
Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027
PMCID:
PMC6554723
AbstractArticlePDF–2.0M
12.
TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology
Athanasia Stoupa, Frédéric Adam, Dulanjalee Kariyawasam, Catherine Strassel, Sanjay Gawade, Gabor Szinnai, Alexandre Kauskot, Dominique Lasne, Carsten Janke, Kathiresan Natarajan, Alain Schmitt, Christine Bole‐Feysot, Patrick Nitschke, Juliane Léger, Fabienne Jabot‐Hanin, Frédéric Tores, Anita Michel, Arnold Munnich, Claude Besmond, Raphaël Scharfmann, François Lanza, Delphine Borgel, Michel Polak, Aurore Carré
EMBO Mol Med. 2018 Dec; 10(12): e9569. Published online 2018 Nov 19. doi: 10.15252/emmm.201809569
PMCID:
PMC6284387
AbstractArticlePDF–2.4M
13.
Relationship between the dimerization of thyroglobulin and its ability to form triiodothyronine
Cintia E. Citterio, Yoshiaki Morishita, Nada Dakka, Balaji Veluswamy, Peter Arvan
J Biol Chem. 2018 Mar 30; 293(13): 4860–4869. Published online 2018 Feb 12. doi: 10.1074/jbc.RA118.001786
PMCID:
PMC5880145
AbstractArticlePDF–2.2M
14.
A branching morphogenesis program governs embryonic growth of the thyroid gland
Shawn Liang, Ellen Johansson, Guillermo Barila, Daniel L. Altschuler, Henrik Fagman, Mikael Nilsson
Development. 2018 Jan 15; 145(2): dev146829. doi: 10.1242/dev.146829
PMCID:
PMC5825846
AbstractArticle
15.
Runx2 Deficiency in Mice Causes Decreased Thyroglobulin Expression and Hypothyroidism
Toyoshi Endo, Tetsuro Kobayashi
Mol Endocrinol. June 1, 2010; 24(6): 1267–1273. doi: 10.1210/me.2010-0056
PMCID:
PMC5417472
AbstractArticle
16.
Coumestrol inhibits autoantibody production through modulating Th1 response in experimental autoimmune thyroiditis
Xiaojing Jin, Shujun Wang, Xuemin Zhao, Qian Jin, Chenling Fan, Jing Li, Zhongyan Shan, Weiping Teng
Oncotarget. 2016 Aug 16; 7(33): 52797–52809. Published online 2016 Jun 30. doi: 10.18632/oncotarget.10353
PMCID:
PMC5288149
AbstractArticlePDF–2.0M
17.
Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly
Mylah Villacorte, Anne-Sophie Delmarcelle, Manon Lernoux, Mahé Bouquet, Pascale Lemoine, Jennifer Bolsée, Lieve Umans, Susana Chuva de Sousa Lopes, Patrick Van Der Smissen, Takako Sasaki, Guido Bommer, Patrick Henriet, Samuel Refetoff, Frédéric P. Lemaigre, An Zwijsen, Pierre J. Courtoy, Christophe E. Pierreux
Development. 2016 Jun 1; 143(11): 1958–1970. doi: 10.1242/dev.134171
PMCID:
PMC4920163
AbstractArticle
18.
Revising the embryonic origin of thyroid C cells in mice and humans
Ellen Johansson, Louise Andersson, Jessica Örnros, Therese Carlsson, Camilla Ingeson-Carlsson, Shawn Liang, Jakob Dahlberg, Svante Jansson, Luca Parrillo, Pietro Zoppoli, Guillermo O. Barila, Daniel L. Altschuler, Daniela Padula, Heiko Lickert, Henrik Fagman, Mikael Nilsson
Development. 2015 Oct 15; 142(20): 3519–3528. doi: 10.1242/dev.126581
PMCID:
PMC4631767
AbstractArticle
19.
Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span
L. Ashley Watson, Lauren A. Solomon, Jennifer Ruizhe Li, Yan Jiang, Matthew Edwards, Kazuo Shin-ya, Frank Beier, Nathalie G. Bérubé
J Clin Invest. 2013 May 1; 123(5): 2049–2063. Published online 2013 Apr 8. doi: 10.1172/JCI65634
PMCID:
PMC3635723
AbstractArticlePDF–5.6M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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