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Select item 112410561.

Impaired Tertiary Dentin Secretion after Shallow Injury in Tgfbr2-Deficient Dental Pulp Cells Is Rescued by Extended CGRP Signaling

Monica Stanwick, Fatma Fenesha, Ahmed Hamid, Khushroop Kang, Dane Kanniard, Irene Kim, Nicholas Mandarano, Fernanda L. Schumacher, Sarah B. Peters

Int J Mol Sci. 2024 Jul; 25(13): 6847. Published online 2024 Jun 21. doi: 10.3390/ijms25136847

PMCID:: PMC11241056

Abstract Article PDF–16M

Select item 112402842.

T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103⁺ intestine-resident memory CD8⁺ T cells

Liwen Wang, Shruti Mishra, Kenneth Ka-Ho Fan, Sara Quon, Guo Li, Bingfei Yu, Wei Liao, Yong Liu, Xin Zhang, Yuanzheng Qiu, Yue Li, Ananda W. Goldrath, Chaoyu Ma, Nu Zhang

Cell Rep. Author manuscript; available in PMC 2024 Jul 12.

Published in final edited form as: Cell Rep. 2024 Jun 25; 43(6): 114258. Published online 2024 May 22. doi: 10.1016/j.celrep.2024.114258

PMCID:: PMC11240284

Abstract Article PDF–3.1M

Select item 110963823.

Hepatocytes differentiate into intestinal epithelial cells through a hybrid epithelial/mesenchymal cell state in culture

Shizuka Miura, Kenichi Horisawa, Tokuko Iwamori, Satoshi Tsujino, Kazuya Inoue, Satsuki Karasawa, Junpei Yamamoto, Yasuyuki Ohkawa, Sayaka Sekiya, Atsushi Suzuki

Nat Commun. 2024; 15: 3940. Published online 2024 May 15. doi: 10.1038/s41467-024-47869-2

PMCID:: PMC11096382

Abstract Article PDF–11M

Select item 110901424.

TGFβ Signaling Dysregulation May Contribute to COL4A1-Related Glaucomatous Optic Nerve Damage

Mao Mao, Yien-Ming Kuo, Alfred K. Yu, Cassandre Labelle-Dumais, Yvonne Ou, Douglas B. Gould

Invest Ophthalmol Vis Sci. 2024 May; 65(5): 15. Published online 2024 May 8. doi: 10.1167/iovs.65.5.15

PMCID:: PMC11090142

Abstract Article PDF–13M

Select item 110303555.

Genetic Analysis and Functional Assessment of a TGFBR2 Variant in Micrognathia and Cleft Palate

JES-Rite Michaels, Ammar Husami, Andrew M. Vontell, Samantha A. Brugmann, Rolf W. Stottmann

Version 1. bioRxiv. Preprint. 2024 Apr 11. doi: 10.1101/2024.04.08.588524

PMCID:: PMC11030355

Abstract Article PDF–1.2M

Select item 109176606.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107838037.

Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

Tommaso Torcellan, Christin Friedrich, Rémi Doucet-Ladevèze, Thomas Ossner, Virgínia Visaconill Solé, Sofie Riedmann, Milas Ugur, Fabian Imdahl, Stephan P. Rosshart, Sebastian J. Arnold, Mercedes Gomez de Agüero, Nicola Gagliani, Richard A. Flavell, Simone Backes, Wolfgang Kastenmüller, Georg Gasteiger

Immunity. 2024 Jan 9; 57(1): 124–140.e7. doi: 10.1016/j.immuni.2023.11.018

PMCID:: PMC10783803

Abstract Article

Select item 105473008.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 104716359.

Autocrine TGF-β-positive feedback in profibrotic AT2-lineage cells plays a crucial role in non-inflammatory lung fibrogenesis

Yasunori Enomoto, Hiroaki Katsura, Takashi Fujimura, Akira Ogata, Saori Baba, Akira Yamaoka, Miho Kihara, Takaya Abe, Osamu Nishimura, Mitsutaka Kadota, Daisuke Hazama, Yugo Tanaka, Yoshimasa Maniwa, Tatsuya Nagano, Mitsuru Morimoto

Nat Commun. 2023; 14: 4956. Published online 2023 Aug 31. doi: 10.1038/s41467-023-40617-y

PMCID:: PMC10471635

Abstract Article PDF–3.8M

Select item 1046330710.

SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression

Nuno Bastos, Stéphanie A. Castaldo, Bárbara Adem, José C. Machado, Carlos A. Melo, Sonia A. Melo

J Transl Med. 2023; 21: 578. Published online 2023 Aug 28. doi: 10.1186/s12967-023-04448-1

PMCID:: PMC10463307

Abstract Article PDF–1.8M

Select item 1040154811.

SPSB1‐mediated inhibition of TGF‐β receptor‐II impairs myogenesis in inflammation

Yi Li, Niklas Dörmann, Björn Brinschwitz, Melanie Kny, Elisa Martin, Kirsten Bartels, Ning Li, Priyanka Voori Giri, Stefan Schwanz, Michael Boschmann, Susanne Hille, Britta Fielitz, Tobias Wollersheim, Julius Grunow, Stephan B. Felix, Steffen Weber‐Carstens, Friedrich C. Luft, Oliver J. Müller, Jens Fielitz

J Cachexia Sarcopenia Muscle. 2023 Aug; 14(4): 1721–1736. Published online 2023 May 20. doi: 10.1002/jcsm.13252

PMCID:: PMC10401548

Abstract Article PDF–8.6M

Select item 1033049012.

Periostin⁺ stromal cells guide lymphovascular invasion by cancer cells

Jamie L. Null, Dae Joong Kim, James V. McCann, Patcharin Pramoonjago, Jay W. Fox, Jianhao Zeng, Pankaj Kumar, Lincy Edatt, Chad V. Pecot, Andrew C. Dudley

Cancer Res. Author manuscript; available in PMC 2024 Jan 5.

Published in final edited form as: Cancer Res. 2023 Jul 5; 83(13): 2105–2122. doi: 10.1158/0008-5472.CAN-22-2412

PMCID:: PMC10330490

Abstract Article PDF–2.5M

Select item 1031092913.

β-Catenin regulates endocardial cushion growth by suppressing p21

Huahua Liu, Pengfei Lu, Shan He, Yuru Luo, Yuan Fang, Sonia Benkaci, Bingruo Wu, Yidong Wang, Bin Zhou

Life Sci Alliance. 2023 Sep; 6(9): e202302163. Published online 2023 Jun 29. doi: 10.26508/lsa.202302163

PMCID:: PMC10310929

Abstract Article PDF–4.2M

Select item 1011042314.

Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development

Alyssa M. McCoy, Omar Lakhdari, Sayane Shome, Kaitlin Caoili, Gilberto E. Hernandez, Nima Aghaeepour, Lindsay D. Butcher, Kathleen Fisch, Lawrence S. Prince

Development. 2023 Mar 1; 150(5): dev200839. Published online 2023 Mar 3. doi: 10.1242/dev.200839

PMCID:: PMC10110423

Abstract Article

Select item 1010611815.

Epithelial-intrinsic defects in TGFβR signaling drive local allergic inflammation manifesting as eosinophilic esophagitis

Karen Laky, Jessica L. Kinard, Jenny Min Li, Ian N. Moore, Justin Lack, Elizabeth R. Fischer, Juraj Kabat, Rachel Latanich, Nicholas C. Zachos, Ajinkya R. Limkar, Katherine A. Weissler, Robert W. Thompson, Thomas A. Wynn, Harry C. Dietz, Anthony L. Guerrerio, Pamela A. Frischmeyer-Guerrerio

Sci Immunol. Author manuscript; available in PMC 2023 Apr 16.

Published in final edited form as: Sci Immunol. 2023 Jan 6; 8(79): eabp9940. Published online 2023 Jan 6. doi: 10.1126/sciimmunol.abp9940

PMCID:: PMC10106118

Abstract Article PDF–3.6M

Select item 1001303916.

Transforming Growth Factor-β1 Regulates Peroxisomal Genes/Proteins via Smad Signaling in Idiopathic Pulmonary Fibrosis Fibroblasts and Transgenic Mouse Models

Gani Oruqaj, Srikanth Karnati, Lakshmi Kanth Kotarkonda, Eistine Boateng, Marek Bartkuhn, Wenming Zhang, Clemens Ruppert, Andreas Günther, Laurent Bartholin, Wei Shi, Eveline Baumgart-Vogt

Am J Pathol. 2023 Mar; 193(3): 259–274. doi: 10.1016/j.ajpath.2022.11.006

PMCID:: PMC10013039

Abstract Article PDF–3.9M

Select item 999598417.

RAB23 regulates musculoskeletal development and patterning

Md. Rakibul Hasan, Anna Koskenranta, Kirsi Alakurtti, Maarit Takatalo, David P. Rice

Front Cell Dev Biol. 2023; 11: 1049131. Published online 2023 Feb 23. doi: 10.3389/fcell.2023.1049131

PMCID:: PMC9995984

Abstract Article PDF–8.4M

Select item 995812118.

Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II

Jia-yun Ni, Xin Wang, Hong-yan Xie, Ning-hao Yang, Jing-yao Li, Xi-ang Sun, Heng-jiang Guo, Li Zhou, Wei Zhang, Jun Liu, Li-min Lu

Acta Pharmacol Sin. 2023 Mar; 44(3): 584–595. Published online 2022 Aug 31. doi: 10.1038/s41401-022-00977-5

PMCID:: PMC9958121

Abstract Article PDF–5.5M

Select item 990439019.

Small intestine and colon tissue-resident memory CD8⁺ T cells exhibit molecular heterogeneity and differential dependence on Eomes

Yun Hsuan Lin, Han G. Duong, Abigail E. Limary, Eleanor S. Kim, Paul Hsu, Shefali A. Patel, William H. Wong, Cynthia S. Indralingam, Yi Chia Liu, Priscilla Yao, Natalie R. Chiang, Sara A. Vandenburgh, Taylor R. Anderson, Jocelyn G. Olvera, Amir Ferry, Kennidy K. Takehara, Wenhao Jin, Matthew S. Tsai, Gene W. Yeo, Ananda W. Goldrath, John T. Chang

Immunity. Author manuscript; available in PMC 2024 Jan 10.

Published in final edited form as: Immunity. 2023 Jan 10; 56(1): 207–223.e8. Published online 2022 Dec 28. doi: 10.1016/j.immuni.2022.12.007

PMCID:: PMC9904390

Abstract Article PDF–3.6M

Select item 983421820.

TGFβ1⁺CCR5⁺ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice

Jinbo Li, Zhenqiang Yao, Xin Liu, Rong Duan, Xiangjiao Yi, Akram Ayoub, James O. Sanders, Addisu Mesfin, Lianping Xing, Brendan F. Boyce

Nat Commun. 2023; 14: 159. Published online 2023 Jan 11. doi: 10.1038/s41467-023-35801-z

PMCID:: PMC9834218

Abstract Article PDF–4.1M

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