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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 103871102.

Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development

Jiyoung Lee, Yeonjoo Kim, Paris Ataliotis, Hyung-Goo Kim, Dae-Won Kim, Dorothy C. Bennett, Nigel A. Brown, Lawrence C. Layman, Soo-Hyun Kim

Sci Rep. 2023; 13: 12309. Published online 2023 Jul 29. doi: 10.1038/s41598-023-38017-9

PMCID:: PMC10387110

Abstract Article PDF–11M

Select item 102037103.

Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos

Lu Yan, Hailing Yin, Yiwei Mi, Yu Wu, Yufang Zheng

Front Cell Dev Biol. 2023; 11: 1084245. Published online 2023 May 9. doi: 10.3389/fcell.2023.1084245

PMCID:: PMC10203710

Abstract Article PDF–4.6M

Select item 97185324.

Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis

Xiaodong Li, Patrick J Gordon, John A Gaynes, Alexandra W Fuller, Randy Ringuette, Clayton P Santiago, Valerie Wallace, Seth Blackshaw, Pulin Li, Edward M Levine

eLife. 2022; 11: e78342. Published online 2022 Dec 2. doi: 10.7554/eLife.78342

PMCID:: PMC9718532

Abstract Article PDF–14M

Select item 90427085.

Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling

Bandarigoda Nipunika Somatilaka, Sun-Hee Hwang, Vivek Reddy Palicharla, Kevin Andrew White, Hemant Badgandi, John Michael Shelton, Saikat Mukhopadhyay

Dev Cell. Author manuscript; available in PMC 2022 Apr 27.

Published in final edited form as: Dev Cell. 2020 Sep 28; 54(6): 710–726.e8. Published online 2020 Jul 22. doi: 10.1016/j.devcel.2020.06.034

PMCID:: PMC9042708

Abstract Article PDF–3.9M

Select item 89187896.

An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea

Wenguang Yin, Andreas Liontos, Janine Koepke, Maroua Ghoul, Luciana Mazzocchi, Xinyuan Liu, Chunyan Lu, Haoyu Wu, Athanasios Fysikopoulos, Alexandros Sountoulidis, Werner Seeger, Clemens Ruppert, Andreas Günther, Didier Y. R. Stainier, Christos Samakovlis

Development. 2022 Feb 1; 149(3): dev199804. Published online 2022 Feb 7. doi: 10.1242/dev.199804

PMCID:: PMC8918789

Abstract Article

Select item 83788487.

Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner

Sun-Hee Hwang, Bandarigoda N Somatilaka, Kevin White, Saikat Mukhopadhyay

eLife. 2021; 10: e67121. Published online 2021 Aug 4. doi: 10.7554/eLife.67121

PMCID:: PMC8378848

Abstract Article PDF–9.0M

Select item 83404418.

Expression of Sonic Hedgehog and pathway components in the embryonic mouse head: anatomical relationships between regulators of positive and negative feedback

Crystal L. Sigulinsky, Xiaodong Li, Edward M. Levine

BMC Res Notes. 2021; 14: 300. Published online 2021 Aug 5. doi: 10.1186/s13104-021-05714-5

PMCID:: PMC8340441

Abstract Article PDF–4.5M

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 785998010.

Functionally distinctive Ptch receptors establish multimodal Hedgehog signaling in the tooth epithelial stem cell niche

Martin Binder, Piotr Chmielarz, Peter J McKinnon, Leah Biggs, Irma Thesleff, Anamaria Balic

Stem Cells. Author manuscript; available in PMC 2021 Feb 4.

Published in final edited form as: Stem Cells. 2019 Sep; 37(9): 1238–1248. Published online 2019 Jun 10. doi: 10.1002/stem.3042

PMCID:: PMC7859980

Abstract Article PDF–2.2M

Select item 760987611.

Aberrant and constitutive expression of FOXL2 impairs ovarian development and functions in mice

Barbara Nicol, Karina Rodriguez, Humphrey H-C Yao

Biol Reprod. 2020 Nov; 103(5): 966–977. Published online 2020 Aug 25. doi: 10.1093/biolre/ioaa146

PMCID:: PMC7609876

Abstract Article PDF–2.7M

Select item 736370612.

Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ

Kan Saito, Frederic Michon, Aya Yamada, Hiroyuki Inuzuka, Satoko Yamaguchi, Emiko Fukumoto, Keigo Yoshizaki, Takashi Nakamura, Makiko Arakaki, Yuta Chiba, Masaki Ishikawa, Hideyuki Okano, Irma Thesleff, Satoshi Fukumoto

iScience. 2020 Jul 24; 23(7): 101329. Published online 2020 Jun 30. doi: 10.1016/j.isci.2020.101329

PMCID:: PMC7363706

Abstract Article PDF–9.9M

Select item 718175113.

Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration

Yeonjoo Kim, Jiyoung Lee, Maisa Seppala, Martyn T. Cobourne, Soo-Hyun Kim

Nat Commun. 2020; 11: 1994. Published online 2020 Apr 24. doi: 10.1038/s41467-020-15897-3

Correction in:: Nat Commun. 2020; 11: 2275.

PMCID:: PMC7181751

Abstract Article PDF–5.9M

Select item 650659914.

VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland

Prestina Smith, Nathan Godde, Stefany Rubio, Melawit Tekeste, Eszter K. Vladar, Jeffrey D. Axelrod, Deborah J. Henderson, Michal Milgrom-Hoffman, Patrick O. Humbert, Lindsay Hinck

Sci Rep. 2019; 9: 7079. Published online 2019 May 8. doi: 10.1038/s41598-019-43444-8

PMCID:: PMC6506599

Abstract Article PDF–2.9M

Select item 620489615.

The protein-specific activities of the transmembrane modules of Ptch1 and Ptch2 are determined by their adjacent protein domains

Andrew J. Fleet, Paul A. Hamel

J Biol Chem. 2018 Oct 26; 293(43): 16583–16595. Published online 2018 Aug 30. doi: 10.1074/jbc.RA118.004478

PMCID:: PMC6204896

Abstract Article PDF–1.4M

Select item 582301116.

YAP/TAZ and Hedgehog coordinate growth and patterning in gastrointestinal mesenchyme

Jennifer L. Cotton, Qi Li, Lifang Ma, Joo-Seop Park, Jiayi Wang, Jianhong Ou, Lihua J. Zhu, Y. Tony Ip, Randy L. Johnson, Junhao Mao

Dev Cell. Author manuscript; available in PMC 2018 Oct 9.

Published in final edited form as: Dev Cell. 2017 Oct 9; 43(1): 35–47.e4. Published online 2017 Sep 21. doi: 10.1016/j.devcel.2017.08.019

PMCID:: PMC5823011

Abstract Article PDF–3.7M

Select item 579105117.

Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction

Sepideh Sheybani-Deloui, Lijun Chi, Marian V. Staite, Jason E. Cain, Brian J. Nieman, R. Mark Henkelman, Brandon J. Wainwright, S. Steven Potter, Darius J. Bagli, Armando J. Lorenzo, Norman D. Rosenblum

J Am Soc Nephrol. 2018 Feb; 29(2): 532–544. Published online 2017 Nov 6. doi: 10.1681/ASN.2017050482

PMCID:: PMC5791051

Abstract Article

Select item 556990618.

Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model

Maria A. Hoelzl, Karin Heby-Henricson, Marco Gerling, José M. Dias, Raoul V. Kuiper, Cornelius Trünkle, Åsa Bergström, Johan Ericson, Rune Toftgård, Stephan Teglund

Dev Biol. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: Dev Biol. 2017 Sep 1; 429(1): 132–146. Published online 2017 Jul 5. doi: 10.1016/j.ydbio.2017.06.037

PMCID:: PMC5569906

Abstract Article PDF–3.2M

Select item 546685419.

An essential role of intestinal cell kinase in lung development is linked to the perinatal lethality of human ECO syndrome

Yixin Tong, So Hyun Park, Di Wu, Wenhao Xu, Stacey J. Guillot, Li Jin, Xudong Li, Yalin Wang, Chyuan-Sheng Lin, Zheng Fu

FEBS Lett. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: FEBS Lett. 2017 May; 591(9): 1247–1257. Published online 2017 Apr 21. doi: 10.1002/1873-3468.12644

PMCID:: PMC5466854

Abstract Article PDF–1.1M

Select item 536044620.

YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis

Chuwen Lin, Erica Yao, Kuan Zhang, Xuan Jiang, Stacey Croll, Katherine Thompson-Peer, Pao-Tien Chuang

eLife. 2017; 6: e21130. Published online 2017 Mar 21. doi: 10.7554/eLife.21130

PMCID:: PMC5360446

Abstract Article PDF–11M

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