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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 93043692.

SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction

Huaping Zheng, Linna Gu, Fulei Zhao, Chen Zhang, Zhen Wang, Hong Zhou, Zhonglan Hu, Xiaoqiong Wei, Xiao Liu, Feng Luo, Fanlian Zeng, Qixiang Zhao, Yan Hao, Yawen Hu, Xiaoyan Wang, Jing Hu, Jiadong Yu, Wenling Wu, Yifan Zhou, Pei Zhou, Chengcheng Yue, Nongyu Huang, Kaijun Cui, Wei Li, Jiong Li

Cell Death Dis. 2022 Jul; 13(7): 635. Published online 2022 Jul 21. doi: 10.1038/s41419-022-05045-8

PMCID:: PMC9304369

Abstract Article PDF–4.6M

Select item 93036843.

Two novel mutations of SERPINB7 in eight cases of Nagashima‐type palmoplantar keratosis in the Chinese population

Tong Xiao, Yan Liu, Tian Wang, Junru Ren, Yumin Xia, Xiaopeng Wang

J Dermatol. 2022 May; 49(5): 539–544. Published online 2022 Feb 17. doi: 10.1111/1346-8138.16310

PMCID:: PMC9303684

Abstract Article PDF–1001K

Select item 92924134.

Proteomic analysis of ubiquitination substrates reveals a CTLH E3 ligase complex‐dependent regulation of glycolysis

Matthew E. R. Maitland, Miljan Kuljanin, Xu Wang, Gilles A. Lajoie, Caroline Schild‐Poulter

FASEB J. 2021 Sep; 35(9): e21825. Published online 2021 Aug 12. doi: 10.1096/fj.202100664R

PMCID:: PMC9292413

Abstract Article PDF–1.5M

Select item 88316705.

Acral Peeling in Nagashima Type Palmo-plantar Keratosis Patients Reveals the Role of Serine Protease Inhibitor B 7 in Keratinocyte Adhesion

Eran Cohen-Barak, Wassim Azzam, Jennifer L. Koetsier, Nada Danial-Farran, Moran Barcan, Maysa Hriesh, Morad Khayat, Natalia Edison, Judith Krausz, Chen Gafni-Amsalem, Akiharu Kubo, Lisa M. Godsel, Michael Ziv, Stavit Allon-Shalev

Exp Dermatol. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Exp Dermatol. 2022 Feb; 31(2): 214–222. Published online 2021 Aug 17. doi: 10.1111/exd.14444

PMCID:: PMC8831670

Abstract Article PDF–1.3M

Select item 85664736.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 63900428.

Systematic screening and identification of novel psoriasis-specific genes from the transcriptome of psoriasis-like keratinocytes

Zhen Wang, Huaping Zheng, Hong Zhou, Nongyu Huang, Xiaoqiong Wei, Xiao Liu, Xiu Teng, Zhonglan Hu, Jun Zhang, Xikun Zhou, Wei Li, Jiong Li

Mol Med Rep. 2019 Mar; 19(3): 1529–1542. Published online 2018 Dec 20. doi: 10.3892/mmr.2018.9782

PMCID:: PMC6390042

Abstract Article PDF–1.7M

Select item 60777229.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 510189211.

Nagashima-type palmoplantar keratosis in a Chinese Han population

Jia Zhang, Guolong Zhang, Cheng Ni, Ruhong Cheng, Jianying Liang, Ming Li, Zhirong Yao

Mol Med Rep. 2016 Nov; 14(5): 4049–4054. Published online 2016 Sep 21. doi: 10.3892/mmr.2016.5757

PMCID:: PMC5101892

Abstract Article PDF–958K

Select item 484178312.

The cell proliferation antigen Ki-67 organises heterochromatin

Michal Sobecki, Karim Mrouj, Alain Camasses, Nikolaos Parisis, Emilien Nicolas, David Llères, François Gerbe, Susana Prieto, Liliana Krasinska, Alexandre David, Manuel Eguren, Marie-Christine Birling, Serge Urbach, Sonia Hem, Jérôme Déjardin, Marcos Malumbres, Philippe Jay, Vjekoslav Dulic, Denis LJ Lafontaine, Robert Feil, Daniel Fisher

eLife. 2016; 5: e13722. Published online 2016 Mar 7. doi: 10.7554/eLife.13722

PMCID:: PMC4841783

Abstract Article PDF–5.1M

Select item 475389613.

Association of Megsin Gene Variants With IgA Nephropathy in Northwest Chinese Population: A STROBE-Compliant Observational Study

Lin-Ting Wei, Rong-Guo Fu, Jie Gao, Qiao-Ling Yu, Feng-Ming Dong, Zhe Wang, Meng Wang, Xing-Han Liu, Zhi-Jun Dai

Medicine (Baltimore) 2016 Feb; 95(6): e2694. Published online 2016 Feb 12. doi: 10.1097/MD.0000000000002694

PMCID:: PMC4753896

Abstract Article PDF–186K

Select item 461721114.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 425434115.

Maternal Serum Serpin B7 Is Associated With Early Spontaneous Preterm Birth

Samuel Parry, Heping Zhang, Joseph Biggio, Radek Bukowski, Michael Varner, Yaji Xu, William W. Andrews, George R. Saade, M. Sean Esplin, Rita Leite, John Ilekis, Uma M. Reddy, Yoel Sadovsky, Ian A. Blair, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Genomic and Proteomic Network for Preterm Birth Research (GPN-PBR). All authors contributed substantially to the design, implementation, data analysis, and preparation and review of the manuscript.

Am J Obstet Gynecol. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Am J Obstet Gynecol. 2014 Dec; 211(6): 678.e1–678.e12. Published online 2014 Jun 19. doi: 10.1016/j.ajog.2014.06.035

PMCID:: PMC4254341

Abstract Article PDF–1.0M

Select item 388007716.

Update of the human and mouse SERPIN gene superfamily

Claire Heit, Brian C Jackson, Monica McAndrews, Mathew W Wright, David C Thompson, Gary A Silverman, Daniel W Nebert, Vasilis Vasiliou

Hum Genomics. 2013; 7(1): 22. Published online 2013 Oct 30. doi: 10.1186/1479-7364-7-22

PMCID:: PMC3880077

Abstract Article PDF–595K

Select item 382412717.

Mutations in SERPINB7, Encoding a Member of the Serine Protease Inhibitor Superfamily, Cause Nagashima-type Palmoplantar Keratosis

Akiharu Kubo, Aiko Shiohama, Takashi Sasaki, Kazuhiko Nakabayashi, Hiroshi Kawasaki, Toru Atsugi, Showbu Sato, Atsushi Shimizu, Shuji Mikami, Hideaki Tanizaki, Masaki Uchiyama, Tatsuo Maeda, Taisuke Ito, Jun-ichi Sakabe, Toshio Heike, Torayuki Okuyama, Rika Kosaki, Kenjiro Kosaki, Jun Kudoh, Kenichiro Hata, Akihiro Umezawa, Yoshiki Tokura, Akira Ishiko, Hironori Niizeki, Kenji Kabashima, Yoshihiko Mitsuhashi, Masayuki Amagai

Am J Hum Genet. 2013 Nov 7; 93(5): 945–956. doi: 10.1016/j.ajhg.2013.09.015

PMCID:: PMC3824127

Abstract Article PDF–3.2M

Select item 355934718.

Modulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1

Joachim Denner, Magdalena Eschricht, Michael Lauck, Marwan Semaan, Philipp Schlaermann, Hyunmi Ryu, Levent Akyüz

PLoS One. 2013; 8(1): e55199. Published online 2013 Jan 30. doi: 10.1371/journal.pone.0055199

PMCID:: PMC3559347

Abstract Article PDF–1.0M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 293716320.

Genetic Analysis of Diabetic Nephropathy on Chromosome 18 in African Americans: Linkage Analysis and Dense SNP Mapping

Caitrin W. McDonough, Meredith A. Bostrom, Lingyi Lu, Pamela J. Hicks, Carl D. Langefeld, Jasmin Divers, Josyf C. Mychaleckyj, Barry I. Freedman, Donald W. Bowden

Hum Genet. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: Hum Genet. 2009 Dec; 126(6): 805–817. doi: 10.1007/s00439-009-0732-8

PMCID:: PMC2937163

Abstract Article PDF–768K

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