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Items: 1 to 20 of 162

1.
BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway
Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo
Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361
PMCID:
PMC11373599
AbstractArticlePDF–11M
2.
MiR-126 promotes coxsackievirus replication by mediating cross-talk of ERK1/2 and Wnt/β-catenin signal pathways
Xin Ye, Maged Gomaa Hemida, Ye Qiu, Paul J. Hanson, Huifang Mary Zhang, Decheng Yang
Cell Mol Life Sci. 2013 Dec; 70(23): 4631–4644. Published online 2013 Jun 30. doi: 10.1007/s00018-013-1411-4
PMCID:
PMC11113642
AbstractArticlePDF–1.4M
3.
Role of Wnt co-receptor LRP6 in triple negative breast cancer cell migration and invasion
Jinlu Ma, Wenyan Lu, Dongquan Chen, Bo Xu, Yonghe Li
J Cell Biochem. Author manuscript; available in PMC 2024 Mar 12.
Published in final edited form as: J Cell Biochem. 2017 Sep; 118(9): 2968–2976. Published online 2017 May 30. doi: 10.1002/jcb.25956
PMCID:
PMC10928515
AbstractArticlePDF–1.7M
4.
The inhibition of YTHDF3/m6A/LRP6 reprograms fatty acid metabolism and suppresses lymph node metastasis in cervical cancer
Sheng Zhong, Quanwei Guo, Xiaona Chen, Xiaomin Luo, Yufei Long, Tuotuo Chong, Ming Ye, Hui He, Anwei Lu, Keyi Ao, Minuo Yin, Aimin Xu, Xin Li, Yi Hao, Xia Guo
Int J Biol Sci. 2024; 20(3): 916–936. Published online 2024 Jan 12. doi: 10.7150/ijbs.87203
PMCID:
PMC10797697
AbstractArticlePDF–13M
5.
A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer’s disease
Megan E. Jones, Johanna Büchler, Tom Dufor, Ernest Palomer, Samuel Teo, Nuria Martin-Flores, Katharina Boroviak, Emmanouil Metzakopian, Alasdair Gibb, Patricia C. Salinas
Sci Adv. 2023 Jan; 9(2): eabo7421. Published online 2023 Jan 13. doi: 10.1126/sciadv.abo7421
PMCID:
PMC10624429
AbstractArticlePDF–1.8M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women
Jun Li, Zebing Liu, Yanxia Ren, Han Shao, Siyuan Li
J Orthop Surg Res. 2023; 18: 369. Published online 2023 May 18. doi: 10.1186/s13018-023-03829-y
PMCID:
PMC10193731
AbstractArticlePDF–988K
8.
LRP6/filamentous-actin signaling facilitates osteogenic commitment in mechanically induced periodontal ligament stem cells
Jixiao Wang, Huiqi Yang, Xiaobei Ma, Jiani Liu, Lan Li, Lei Chen, Fulan Wei
Cell Mol Biol Lett. 2023; 28: 7. Published online 2023 Jan 24. doi: 10.1186/s11658-023-00420-5
PMCID:
PMC9872397
AbstractArticlePDF–9.9M
9.
An LRP6 mutation (Arg360His) associated with low bone mineral density but not cardiovascular events in a Caucasian family
Nuria Puente, Ana I. Vega, José L. Hernandez, Jose L. Fernandez-Luna, Jose A. Riancho
Osteoporos Int. 2022; 33(11): 2445–2448. Published online 2022 Jul 15. doi: 10.1007/s00198-022-06494-9
PMCID:
PMC9568478
AbstractArticlePDF–564K
10.
Antibody targeting of E3 ubiquitin ligases for receptor degradation
Hadir Marei, Wen-Ting K. Tsai, Yee-Seir Kee, Karen Ruiz, Jieyan He, Chris Cox, Tao Sun, Sai Penikalapati, Pankaj Dwivedi, Meena Choi, David Kan, Pablo Saenz-Lopez, Kristel Dorighi, Pamela Zhang, Yvonne T. Kschonsak, Noelyn Kljavin, Dhara Amin, Ingrid Kim, Andrew G. Mancini, Thao Nguyen, Chunling Wang, Eric Janezic, Alexander Doan, Elaine Mai, Hongkang Xi, Chen Gu, Melanie Heinlein, Brian Biehs, Jia Wu, Isabelle Lehoux, Seth Harris, Laetitia Comps-Agrar, Dhaya Seshasayee, Frederic J. de Sauvage, Matthew Grimmer, Jing Li, Nicholas J. Agard, Felipe de Sousa e Melo
Nature. 2022; 610(7930): 182–189. Published online 2022 Sep 21. doi: 10.1038/s41586-022-05235-6
PMCID:
PMC9534761
AbstractArticlePDF–18M
11.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
12.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
13.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
14.
circ-LRP6 contributes to osteosarcoma progression by regulating the miR-141-3p/HDAC4/HMGB1 axis
Yali Yu, Guixiang Dong, Zijun Li, Yan Zheng, Zhisong Shi, Guanghui Wang
Int J Oncol. 2022 Apr; 60(4): 38. Published online 2022 Feb 23. doi: 10.3892/ijo.2022.5328
PMCID:
PMC8878724
AbstractArticlePDF–1.2M
15.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
16.
MicroRNA-513c-5p is involved in the pathogenesis of preeclampsia by regulating of low-density lipoprotein receptor-associated protein 6
Qian Zhou, Hongyan Li, Yan Zhang, Wei Peng, Haiyan Hou, Mengqi Gu, Fengyuan Zhang, Xietong Wang, Xiao Gu, Lei Li
BMC Pregnancy Childbirth. 2021; 21: 837. Published online 2021 Dec 20. doi: 10.1186/s12884-021-04069-w
PMCID:
PMC8691017
AbstractArticlePDF–2.1M
17.
Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-Cyp2e1 Signaling
Li-Jie Chen, Xiu-Xian Lin, Jing Guo, Ying Xu, Song-Xia Zhang, Dan Chen, Qing Zhao, Jian Xiao, Guang-Hui Lian, Shi-Fang Peng, Dong Guo, Hong Yang, Yan Shu, Hong-Hao Zhou, Wei Zhang, Yao Chen
Int J Biol Sci. 2021; 17(14): 3936–3953. Published online 2021 Sep 21. doi: 10.7150/ijbs.63732
PMCID:
PMC8495406
AbstractArticlePDF–2.5M
18.
Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer
Huifang Zhu, Zijie Su, Jiong Ning, Liang Zhou, Lifeng Tan, Sapna Sayed, Jiaxing Song, Zhongyuan Wang, Huan Li, Qi Sun, Shanshan Liu, Ou Sha, Feng Leng, Xianxiong Chen, Desheng Lu
Cell Death Dis. 2021 Oct; 12(10): 912. Published online 2021 Oct 6. doi: 10.1038/s41419-021-04211-8
PMCID:
PMC8494741
AbstractArticlePDF–3.8M
19.
Low‐Density Lipoprotein Receptor‐Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes
Hei‐Man Chow, Jacquelyne Ka‐Li Sun, Ronald P. Hart, Kenneth King‐Yip Cheng, Clara H. L. Hung, Tsun‐Ming Lau, Kin‐Ming Kwan
Adv Sci (Weinh) 2021 Aug; 8(16): 2004993. Published online 2021 Jun 27. doi: 10.1002/advs.202004993
PMCID:
PMC8373092
AbstractArticlePDF–8.7M
20.
Unveiling the Roles of Low-Density Lipoprotein Receptor-Related Protein 6 in Intestinal Homeostasis, Regeneration and Oncogenesis
Jennifer Raisch, Anthony Côté-Biron, Marie-Josée Langlois, Caroline Leblanc, Nathalie Rivard
Cells. 2021 Jul; 10(7): 1792. Published online 2021 Jul 15. doi: 10.3390/cells10071792
PMCID:
PMC8307932
AbstractArticlePDF–2.3M

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