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Select item 108973151.

Decoding the function of Atg13 phosphorylation reveals a role of Atg11 in bulk autophagy initiation

Anuradha Bhattacharya, Raffaela Torggler, Wolfgang Reiter, Natalie Romanov, Mariya Licheva, Akif Ciftci, Muriel Mari, Lena Kolb, Dominik Kaiser, Fulvio Reggiori, Gustav Ammerer, David M Hollenstein, Claudine Kraft

EMBO Rep. 2024 Feb; 25(2): 813–831. Published online 2024 Jan 17. doi: 10.1038/s44319-023-00055-9

PMCID:: PMC10897315

Abstract Article PDF–5.5M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105481764.

TOR‐mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly

Weijing Yao, Yuting Chen, Yingcong Chen, Pengwei Zhao, Jing Liu, Yi Zhang, Qiang Jiang, Choufei Wu, Yu Xie, Siyu Fan, Miao Ye, Yigang Wang, Yuyao Feng, Xue Bai, Mingzhu Fan, Shan Feng, Juan Wang, Yixian Cui, Hongguang Xia, Cheng Ma, Zhiping Xie, Liqin Zhang, Qiming Sun, Wei Liu, Cong Yi

EMBO J. 2023 Oct; 42(19): e112814. Published online 2023 Aug 28. doi: 10.15252/embj.2022112814

PMCID:: PMC10548176

Abstract Article PDF–19M

Select item 102977005.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102350866.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 102333687.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 101610638.

Structures of Vac8-containing protein complexes reveal the underlying mechanism by which Vac8 regulates multiple cellular processes

Hyejin Kim, Jihyeon Park, Hyunwoo Kim, Naho Ko, Jumi Park, Eunhong Jang, So Young Yoon, Joyce Anne R. Diaz, Changwook Lee, Youngsoo Jun

Proc Natl Acad Sci U S A. 2023 May 2; 120(18): e2211501120. Published online 2023 Apr 24. doi: 10.1073/pnas.2211501120

PMCID:: PMC10161063

Abstract Article PDF–4.0M

Select item 99104609.

Mec1 regulates PAS recruitment of Atg13 via direct binding with Atg13 during glucose starvation-induced autophagy

Weijing Yao, Yixing Li, Yingcong Chen, Yuting Chen, Pengwei Zhao, Yi Zhang, Qiang Jiang, Yuyao Feng, Fan Yang, Choufei Wu, Huiming Zhong, Yiting Zhou, Qiming Sun, Liqin Zhang, Wei Liu, Cong Yi

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2215126120. Published online 2022 Dec 27. doi: 10.1073/pnas.2215126120

PMCID:: PMC9910460

Abstract Article PDF–1.4M

Select item 920981110.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 891966711.

Cdc14 spatiotemporally dephosphorylates Atg13 to activate autophagy during meiotic divisions

Wenzhi Feng, Orlando Argüello-Miranda, Suhong Qian, Fei Wang

J Cell Biol. 2022 May 2; 221(5): e202107151. Published online 2022 Mar 3. doi: 10.1083/jcb.202107151

PMCID:: PMC8919667

Abstract Article PDF–6.9M

Select item 869386012.

Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation

Anne Schreiber, Ben C. Collins, Colin Davis, Radoslav I. Enchev, Angie Sedra, Rocco D’Antuono, Ruedi Aebersold, Matthias Peter

Mol Cell. 2021 Dec 16; 81(24): 5066–5081.e10. doi: 10.1016/j.molcel.2021.10.024

PMCID:: PMC8693860

Abstract Article

Select item 835461513.

Vac8 determines phagophore assembly site vacuolar localization during nitrogen starvation-induced autophagy

Damian Gatica, Xin Wen, Heesun Cheong, Daniel J. Klionsky

Autophagy. 2021; 17(7): 1636–1648. Published online 2020 Jun 17. doi: 10.1080/15548627.2020.1776474

PMCID:: PMC8354615

Abstract Article PDF–7.4M

Select item 820501514.

Atg21 organizes Atg8 lipidation at the contact of the vacuole with the phagophore

Lena Munzel, Piotr Neumann, Florian B. Otto, Roswitha Krick, Janina Metje-Sprink, Benjamin Kroppen, Narain Karedla, Jörg Enderlein, Michael Meinecke, Ralf Ficner, Michael Thumm

Autophagy. 2021; 17(6): 1458–1478. Published online 2020 Jun 9. doi: 10.1080/15548627.2020.1766332

PMCID:: PMC8205015

Abstract Article PDF–20M

Select item 772147515.

A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits

Florian Wilfling, Chia-Wei Lee, Philipp S. Erdmann, Yumei Zheng, Dawafuti Sherpa, Stefan Jentsch, Boris Pfander, Brenda A. Schulman, Wolfgang Baumeister

Mol Cell. 2020 Dec 3; 80(5): 764–778.e7. doi: 10.1016/j.molcel.2020.10.030

PMCID:: PMC7721475

Abstract Article

Select item 771875116.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 761077817.

Reconstitution of autophagosome nucleation defines Atg9 vesicles as seeds for membrane formation

Justyna Sawa-Makarska, Verena Baumann, Nicolas Coudevylle, Sören von Bülow, Veronika Nogellova, Christine Abert, Martina Schuschnig, Martin Graef, Gerhard Hummer, Sascha Martens

Science. Author manuscript; available in PMC 2021 May 13.

Published in final edited form as: Science. 2020 Sep 4; 369(6508): eaaz7714. Published online 2020 Sep 4. doi: 10.1126/science.aaz7714

PMCID:: PMC7610778

Abstract Article PDF–1.9M

Select item 746956618.

The carboxy terminus of yeast Atg13 binds phospholipid membrane via motifs that overlap with the Vac8-interacting domain

Damián Gatica, Alejandro Damasio, Clarence Pascual, Daniel J. Klionsky, Michael J. Ragusa, Hana Popelka

Autophagy. 2020; 16(6): 1007–1020. Published online 2019 Aug 2. doi: 10.1080/15548627.2019.1648117

PMCID:: PMC7469566

Abstract Article PDF–3.2M

Select item 746949419.

Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways

Jumi Park, Hye-In Kim, Hanbin Jeong, Miriam Lee, Se Hwan Jang, So Young Yoon, Hyejin Kim, Zee-Yong Park, Youngsoo Jun, Changwook Lee

Autophagy. 2020; 16(6): 991–1006. Published online 2019 Sep 12. doi: 10.1080/15548627.2019.1659615

PMCID:: PMC7469494

Abstract Article PDF–7.6M

Select item 713822220.

DeepPhagy: a deep learning framework for quantitatively measuring autophagy activity in Saccharomyces cerevisiae

Ying Zhang, Yubin Xie, Wenzhong Liu, Wankun Deng, Di Peng, Chenwei Wang, Haodong Xu, Chen Ruan, Yongjie Deng, Yaping Guo, Chenjun Lu, Cong Yi, Jian Ren, Yu Xue

Autophagy. 2020; 16(4): 626–640. Published online 2019 Jun 20. doi: 10.1080/15548627.2019.1632622