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Select item 114010341.

Proximity labeling reveals dynamic changes in the SQSTM1 protein network

Alejandro N. Rondón-Ortiz, Lushuang Zhang, Peter E.A. Ash, Avik Basu, Sambhavi Puri, Sophie J.F. van der Spek, Zihan Wang, Luke Dorrian, Andrew Emili, Benjamin Wolozin

J Biol Chem. 2024 Sep; 300(9): 107621. Published online 2024 Aug 3. doi: 10.1016/j.jbc.2024.107621

PMCID:: PMC11401034

Article PDF–5.4M

Select item 113735992.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Article PDF–11M

Select item 112759513.

T-Allele Carriers of Mono Carboxylate Transporter One Gene Polymorphism rs1049434 Demonstrate Altered Substrate Metabolization during Exhaustive Exercise

Benedikt Gasser, Alain Dössegger, Marie-Noëlle Giraud, Martin Flück

Genes (Basel) 2024 Jul; 15(7): 918. Published online 2024 Jul 14. doi: 10.3390/genes15070918

PMCID:: PMC11275951

Article PDF–2.3M

Select item 112602884.

To initiate or not to initiate: A critical assessment of eIF2A, eIF2D, and MCT-1·DENR to deliver initiator tRNA to ribosomes

Daisy J. Grove, Paul J. Russell, Michael G. Kearse

Wiley Interdiscip Rev RNA. Author manuscript; available in PMC 2024 Jul 21.

Published in final edited form as: Wiley Interdiscip Rev RNA. 2024 Mar-Apr; 15(2): e1833. doi: 10.1002/wrna.1833

PMCID:: PMC11260288

Article PDF–938K

Select item 112099355.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Article PDF–3.0M

Select item 111769486.

The N-terminal signature motif on the transporter MCT1 is critical for CD147-mediated trafficking

Devin J. Seka, Annika K. Schulz, Tarjani M. Thaker, Thomas M. Tomasiak

J Biol Chem. 2024 Jun; 300(6): 107333. Published online 2024 May 22. doi: 10.1016/j.jbc.2024.107333

PMCID:: PMC11176948

Article PDF–2.4M

Select item 111053857.

Homology modeling and site-directed mutagenesis identify amino acid residues underlying the substrate selection mechanism of human monocarboxylate transporters 1 (hMCT1) and 4 (hMCT4)

Yuya Futagi, Masaki Kobayashi, Katsuya Narumi, Ayako Furugen, Ken Iseki

Cell Mol Life Sci. 2019 Dec; 76(24): 4905–4921. Published online 2019 May 17. doi: 10.1007/s00018-019-03151-z

PMCID:: PMC11105385

Article PDF–8.2M

Select item 109902778.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Article PDF–3.9M

Select item 109767729.

Oncogenic circ-SLC16A1 promotes progression of non-small cell lung cancer via regulation of the miR-1287-5p/profilin 2 axis

Mingming Jin, Tailei Yuan, Kaisai Tian, Jingjing Li, Qingqing Huang, Yongbin Chi, Gang Huang

Cell Mol Biol Lett. 2024; 29: 43. Published online 2024 Mar 27. doi: 10.1186/s11658-024-00549-x

PMCID:: PMC10976772

Article PDF–3.6M

Select item 1091686610.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Article PDF–4.7M

Select item 1084368411.

Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies

Jakub Chrustowicz, Dawafuti Sherpa, Jerry Li, Christine R. Langlois, Eleftheria C. Papadopoulou, D. Tung Vu, Laura A. Hehl, Özge Karayel, Viola Beier, Susanne von Gronau, Judith Müller, J. Rajan Prabu, Matthias Mann, Gary Kleiger, Arno F. Alpi, Brenda A. Schulman

Mol Cell. Author manuscript; available in PMC 2025 Jan 18.

Published in final edited form as: Mol Cell. 2024 Jan 18; 84(2): 293–308.e14. Published online 2023 Dec 18. doi: 10.1016/j.molcel.2023.11.027

PMCID:: PMC10843684

Article PDF–3.1M

Select item 1076215412.

MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation

Wenna Chi, Na Kang, Linlin Sheng, Sichen Liu, Lei Tao, Xizhi Cao, Ye Liu, Can Zhu, Yuming Zhang, Bolong Wu, Ruiqun Chen, Lili Cheng, Jing Wang, Xiaolin Sun, Xiaohui Liu, Haiteng Deng, Jinliang Yang, Zhanguo Li, Wanli Liu, Ligong Chen

Nat Commun. 2024; 15: 163. Published online 2024 Jan 2. doi: 10.1038/s41467-023-44540-0

PMCID:: PMC10762154

Article PDF–3.1M

Select item 1061767313.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Article PDF–3.6M

Select item 1056587614.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Article PDF–3.7M

Select item 1055867015.

SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle

Xiaowei She, Qi Wu, Zejun Rao, Da Song, Changsheng Huang, Shengjie Feng, Anyi Liu, Lang Liu, Kairui Wan, Xun Li, Chengxin Yu, Cheng Qiu, Xuelai Luo, Junbo Hu, Guihua Wang, Feng Xu, Li Sun

Adv Sci (Weinh) 2023 Oct; 10(28): 2301871. Published online 2023 Aug 4. doi: 10.1002/advs.202301871

PMCID:: PMC10558670

Article PDF–4.4M

Select item 1039866016.

C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains

Julia Jülg, Dieter Edbauer, Christian Behrends

EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895

PMCID:: PMC10398660

Article PDF–2.4M

Select item 1027947217.

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways

Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett

Cell Rep. Author manuscript; available in PMC 2023 Jun 19.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112496. Published online 2023 May 9. doi: 10.1016/j.celrep.2023.112496

PMCID:: PMC10279472

Article PDF–2.9M

Select item 1023742218.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Article PDF–23M

Select item 1020218319.

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage

Fengli Wang, Lingjuan Wang, Shiming Gan, Shenglei Feng, Sijin Ouyang, Xiaoli Wang, Shuiqiao Yuan

Research (Wash D C) 2023; 6: 0091. Published online 2023 Apr 12. doi: 10.34133/research.0091

PMCID:: PMC10202183

Article PDF–18M

Select item 1004918120.

Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review

Ana Silva, Mónica Costa Cerqueira, Beatriz Rosa, Catarina Sobral, Filipa Pinto-Ribeiro, Marta Freitas Costa, Fátima Baltazar, Julieta Afonso

Int J Mol Sci. 2023 Mar; 24(6): 5141. Published online 2023 Mar 7. doi: 10.3390/ijms24065141

PMCID:: PMC10049181

Article PDF–1.4M

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