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Select item 110029271.

Lipidome Unsaturation Affects the Morphology and Proteome of the Drosophila Eye

Mukesh Kumar, Canan Has, Khanh Lam-Kamath, Sophie Ayciriex, Deepshe Dewett, Mhamed Bashir, Clara Poupault, Kai Schuhmann, Henrik Thomas, Oskar Knittelfelder, Bharath Kumar Raghuraman, Robert Ahrends, Jens Rister, Andrej Shevchenko

J Proteome Res. 2024 Apr 5; 23(4): 1188–1199. Published online 2024 Mar 14. doi: 10.1021/acs.jproteome.3c00570

PMCID:: PMC11002927

Abstract Article PDF–4.8M

Select item 101645912.

RNA binding proteins Smaug and Cup induce CCR4–NOT-dependent deadenylation of the nanos mRNA in a reconstituted system

Filip Pekovic, Christiane Rammelt, Jana Kubíková, Jutta Metz, Mandy Jeske, Elmar Wahle

Nucleic Acids Res. 2023 May 8; 51(8): 3950–3970. Published online 2023 Mar 23. doi: 10.1093/nar/gkad159

PMCID:: PMC10164591

Abstract Article PDF–4.6M

Select item 94184433.

A conserved domain of Drosophila RNA-binding protein Pumilio interacts with multiple CCR4–NOT deadenylase complex subunits to repress target mRNAs

Rebecca J. Haugen, René M. Arvola, Robert P. Connacher, Richard T. Roden, Aaron C. Goldstrohm

J Biol Chem. 2022 Sep; 298(9): 102270. Published online 2022 Jul 16. doi: 10.1016/j.jbc.2022.102270

PMCID:: PMC9418443

Abstract Article PDF–2.6M

Select item 86644864.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 70389325.

Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs

René M Arvola, Chung-Te Chang, Joseph P Buytendorp, Yevgen Levdansky, Eugene Valkov, Peter L Freddolino, Aaron C Goldstrohm

Nucleic Acids Res. 2020 Feb 28; 48(4): 1843–1871. Published online 2019 Dec 21. doi: 10.1093/nar/gkz1187

PMCID:: PMC7038932

Abstract Article PDF–8.8M

Select item 69615786.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 68904657.

Drosophila PSI controls circadian period and the phase of circadian behavior under temperature cycle via tim splicing

Lauren E Foley, Jinli Ling, Radhika Joshi, Naveh Evantal, Sebastian Kadener, Patrick Emery

eLife. 2019; 8: e50063. Published online 2019 Nov 8. doi: 10.7554/eLife.50063

PMCID:: PMC6890465

Abstract Article PDF–3.0M

Select item 66488868.

Direct role for the Drosophila GIGYF protein in 4EHP-mediated mRNA repression

Vincenzo Ruscica, Praveen Bawankar, Daniel Peter, Sigrun Helms, Cátia Igreja, Elisa Izaurralde

Nucleic Acids Res. 2019 Jul 26; 47(13): 7035–7048. Published online 2019 May 22. doi: 10.1093/nar/gkz429

PMCID:: PMC6648886

Abstract Article PDF–2.8M

Select item 65351289.

Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD.

Lindsey D. Goodman, Mercedes Prudencio, Nicholas J. Kramer, Luis F. Martinez-Ramirez, Ananth R. Srinivasan, Matthews Lan, Michael J. Parisi, Yongqing Zhu, Jeannie Chew, Casey N. Cook, Amit Berson, Aaron D. Gitler, Leonard Petrucelli, Nancy M. Bonini

Nat Neurosci. Author manuscript; available in PMC 2019 Nov 20.

Published in final edited form as: Nat Neurosci. 2019 Jun; 22(6): 863–874. Published online 2019 May 20. doi: 10.1038/s41593-019-0396-1

Correction in:: Nat Neurosci. 2023 Feb 21

PMCID:: PMC6535128

Abstract Article PDF–3.4M

Select item 616849710.

LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes

Li Zhu, Suresh K. Kandasamy, Susan E. Liao, Ryuya Fukunaga

Nat Commun. 2018; 9: 4031. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06404-w

Correction in:: Nat Commun. 2019; 10: 1074.

PMCID:: PMC6168497

Abstract Article PDF–3.4M

Select item 610929411.

The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models

Carmen Vicente, Rocco Stirparo, Sofie Demeyer, Charles E. de Bock, Olga Gielen, Mardelle Atkins, Jiekun Yan, Georg Halder, Bassem A. Hassan, Jan Cools

J Hematol Oncol. 2018; 11: 108. Published online 2018 Aug 25. doi: 10.1186/s13045-018-0650-0

PMCID:: PMC6109294

Abstract Article PDF–3.1M

Select item 582435712.

Drosophila Bag-of-marbles directly interacts with the CAF40 subunit of the CCR4–NOT complex to elicit repression of mRNA targets

Annamaria Sgromo, Tobias Raisch, Charlotte Backhaus, Csilla Keskeny, Vikram Alva, Oliver Weichenrieder, Elisa Izaurralde

RNA. 2018 Mar; 24(3): 381–395. doi: 10.1261/rna.064584.117

PMCID:: PMC5824357

Abstract Article PDF–16M

Select item 579919413.

Impaired Wnt signaling in dopamine containing neurons is associated with pathogenesis in a rotenone triggered Drosophila Parkinson’s disease model

Flora Stephano, Stella Nolte, Julia Hoffmann, Samar El-Kholy, Jakob von Frieling, Iris Bruchhaus, Christine Fink, Thomas Roeder

Sci Rep. 2018; 8: 2372. Published online 2018 Feb 5. doi: 10.1038/s41598-018-20836-w

PMCID:: PMC5799194

Abstract Article PDF–2.0M

Select item 570780514.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900215.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 566661916.

Aubergine and piRNAs promote germline stem cell self‐renewal by repressing the proto‐oncogene Cbl

Patricia Rojas‐Ríos, Aymeric Chartier, Stéphanie Pierson, Martine Simonelig

EMBO J. 2017 Nov 2; 36(21): 3194–3211. Published online 2017 Oct 13. doi: 10.15252/embj.201797259

PMCID:: PMC5666619

Abstract Article PDF–3.2M

Select item 554791317.

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia

Kim De Keersmaecker, Zeynep Kalender Atak, Ning Li, Carmen Vicente, Stephanie Patchett, Tiziana Girardi, Valentina Gianfelici, Ellen Geerdens, Emmanuelle Clappier, Michaël Porcu, Idoya Lahortiga, Rossella Lucà, Jiekun Yan, Gert Hulselmans, Hilde Vranckx, Roel Vandepoel, Bram Sweron, Kris Jacobs, Nicole Mentens, Iwona Wlodarska, Barbara Cauwelier, Jacqueline Cloos, Jean Soulier, Anne Uyttebroeck, Claudia Bagni, Bassem A Hassan, Peter Vandenberghe, Arlen W Johnson, Stein Aerts, Jan Cools

Nat Genet. Author manuscript; available in PMC 2017 Aug 8.

Published in final edited form as: Nat Genet. 2013 Feb; 45(2): 186–190. Published online 2012 Dec 23. doi: 10.1038/ng.2508

PMCID:: PMC5547913

Abstract Article PDF–2.2M

Select item 530382918.

A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin

Annamaria Sgromo, Tobias Raisch, Praveen Bawankar, Dipankar Bhandari, Ying Chen, Duygu Kuzuoğlu-Öztürk, Oliver Weichenrieder, Elisa Izaurralde

Nat Commun. 2017; 8: 14307. Published online 2017 Feb 6. doi: 10.1038/ncomms14307

PMCID:: PMC5303829

Abstract Article PDF–3.7M

Select item 520732219.

Distinct modes of recruitment of the CCR4–NOT complex by Drosophila and vertebrate Nanos

Tobias Raisch, Dipankar Bhandari, Kevin Sabath, Sigrun Helms, Eugene Valkov, Oliver Weichenrieder, Elisa Izaurralde

EMBO J. 2016 May 2; 35(9): 974–990. Published online 2016 Mar 11. doi: 10.15252/embj.201593634

PMCID:: PMC5207322

Abstract Article PDF–2.0M

Select item 502578220.

Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster

Hirokazu Okada, H. Alexander Ebhardt, Sibylle Chantal Vonesch, Ruedi Aebersold, Ernst Hafen

Nat Commun. 2016; 7: 12649. Published online 2016 Sep 1. doi: 10.1038/ncomms12649

PMCID:: PMC5025782

Abstract Article PDF–2.2M

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