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Select item 115125871.

Immunity to the microbiota promotes sensory neuron regeneration

Michel Enamorado, Warakorn Kulalert, Seong-Ji Han, Indira Rao, Jeremie Delaleu, Verena M. Link, Daniel Yong, Margery Smelkinson, Louis Gil, Saeko Nakajima, Jonathan L. Linehan, Nicolas Bouladoux, Josette Wlaschin, Juraj Kabat, Olena Kamenyeva, Liwen Deng, Inta Gribonika, Alexander T. Chesler, Isaac M. Chiu, Claire E. Le Pichon, Yasmine Belkaid

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Feb 2; 186(3): 607–620.e17. Published online 2023 Jan 13. doi: 10.1016/j.cell.2022.12.037

PMCID:: PMC11512587

Abstract Article PDF–3.7M

Select item 111075692.

OX40 promotes obesity-induced adipose inflammation and insulin resistance

Bing Liu, Hengchi Yu, Guangyong Sun, Xiaojing Sun, Hua Jin, Chunpan Zhang, Wen Shi, Dan Tian, Kai Liu, Hufeng Xu, Xinmin Li, Jie Yin, Xu Hong, Dong Zhang

Cell Mol Life Sci. 2017 Oct; 74(20): 3827–3840. Published online 2017 Jun 13. doi: 10.1007/s00018-017-2552-7

PMCID:: PMC11107569

Abstract Article PDF–1.9M

Select item 106870853.

The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8⁺ T-cell immunity

Jizhang Yu, Jikai Cui, Xi Zhang, Heng Xu, Zhang Chen, Yuan Li, Yuqing Niu, Song Wang, Shuan Ran, Yanqiang Zou, Weicong Ye, Dan Zhang, Cheng Zhou, Jiahong Xia, Jie Wu

Cell Mol Immunol. 2023 Dec; 20(12): 1445–1456. Published online 2023 Nov 7. doi: 10.1038/s41423-023-01093-y

PMCID:: PMC10687085

Abstract Article PDF–4.8M

Select item 101403714.

CD4⁺ T cell memory is impaired by species-specific cytotoxic differentiation, but not by TCF-1 loss

Tom Hofland, Luca Danelli, Georgina Cornish, Tiziano Donnarumma, Deborah M. Hunt, Luiz P. S. de Carvalho, George Kassiotis

Front Immunol. 2023; 14: 1168125. Published online 2023 Apr 14. doi: 10.3389/fimmu.2023.1168125

PMCID:: PMC10140371

Abstract Article PDF–4.5M

Select item 100403865.

OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum

Tetje C. van der Sluis, Guillaume Beyrend, Esmé T.I. van der Gracht, Tamim Abdelaal, Simon P. Jochems, Robert A. Belderbos, Thomas H. Wesselink, Suzanne van Duikeren, Floortje J. van Haften, Anke Redeker, Laura F. Ouboter, Elham Beyranvand Nejad, Marcel Camps, Kees L.M.C. Franken, Margot M. Linssen, Peter Hohenstein, Noel F.C.C. de Miranda, Hailiang Mei, Adriaan D. Bins, John B.A.G. Haanen, Joachim G. Aerts, Ferry Ossendorp, Ramon Arens

Cell Rep Med. 2023 Mar 21; 4(3): 100939. Published online 2023 Feb 15. doi: 10.1016/j.xcrm.2023.100939

PMCID:: PMC10040386

Abstract Article PDF–6.6M

Select item 92013436.

OX40 Expression in Eosinophils Aggravates OVA-Induced Eosinophilic Gastroenteritis

Longwei Xu, Dan Tian, Minsi Zhou, Jiuyue Ma, Guangyong Sun, Hua Jin, Mingyang Li, Dong Zhang, Jing Wu

Front Immunol. 2022; 13: 841141. Published online 2022 Jun 2. doi: 10.3389/fimmu.2022.841141

PMCID:: PMC9201343

Abstract Article PDF–7.4M

Select item 84357767.

Ddb1 Is Essential for the Expansion of CD4⁺ Helper T Cells by Regulating Cell Cycle Progression and Cell Death

Lingtao Yang, Wei Chen, Li Li, Yueyue Xiao, Shilin Fan, Quan Zhang, Tian Xia, Mengjie Li, Yazhen Hong, Tongjin Zhao, Qiyuan Li, Wen-Hsien Liu, Nengming Xiao

Front Immunol. 2021; 12: 722273. Published online 2021 Aug 30. doi: 10.3389/fimmu.2021.722273

PMCID:: PMC8435776

Abstract Article PDF–16M

Select item 80968628.

Combination Blockade of OX40L and CD30L Inhibits Allergen-driven Memory Th2 Reactivity and Lung Inflammation

Donald T. Gracias, Gurupreet S. Sethi, Amit K. Mehta, Haruka Miki, Rinkesh K. Gupta, Hideo Yagita, Michael Croft

J Allergy Clin Immunol. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: J Allergy Clin Immunol. 2021 Jun; 147(6): 2316–2329. Published online 2020 Nov 5. doi: 10.1016/j.jaci.2020.10.037

PMCID:: PMC8096862

Abstract Article PDF–2.8M

Select item 76771829.

T cell receptor is required for differentiation but not maintenance of intestinal CD4⁺ intraepithelial lymphocytes

Angelina M. Bilate, Mariya London, Tiago B. R. Castro, Luka Mesin, Juliana Bortolatto, Suppawat Kongthong, Audrey Harnagel, Gabriel D. Victora, Daniel Mucida

Immunity. Author manuscript; available in PMC 2021 Nov 17.

Published in final edited form as: Immunity. 2020 Nov 17; 53(5): 1001–1014.e20. Published online 2020 Oct 5. doi: 10.1016/j.immuni.2020.09.003

PMCID:: PMC7677182

Abstract Article PDF–3.0M

Select item 753490010.

RNA-binding protein HuR promotes Th17 cell differentiation and can be targeted to reduce autoimmune neuroinflammation

Jing Chen, Jennifer L. Martindale, Kotb Abdelmohsen, Gaurav Kumar, Paolo M. Fortina, Myriam Gorospe, Abdolmohamad Rostami, Shiguang Yu

J Immunol. Author manuscript; available in PMC 2020 Oct 15.

Published in final edited form as: J Immunol. 2020 Apr 15; 204(8): 2076–2087. Published online 2020 Mar 13. doi: 10.4049/jimmunol.1900769

PMCID:: PMC7534900

Abstract Article PDF–1.8M

Select item 734757211.

Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues

Dominika W. Gajdasik, Fabrina Gaspal, Emily E. Halford, Remi Fiancette, Emma E. Dutton, Claire Willis, Timo Rückert, Chiara Romagnani, Audrey Gerard, Sarah L. Bevington, Andrew S. MacDonald, Marina Botto, Timothy Vyse, David R. Withers

Nat Commun. 2020; 11: 3421. Published online 2020 Jul 9. doi: 10.1038/s41467-020-17293-3

PMCID:: PMC7347572

Abstract Article PDF–2.6M

Select item 731231312.

Critical role of OX40 in drug‐induced acute liver injury

Chunpan Zhang, Hua Jin, Yan Wang, Changying Li, Xinyan Zhao, Yanmeng Li, Wen Shi, Yue Tian, Hufeng Xu, Dan Tian, Kai Liu, Jidong Jia, Guangyong Sun, Dong Zhang

Br J Pharmacol. 2020 Jul; 177(14): 3183–3196. Published online 2020 Apr 5. doi: 10.1111/bph.15041

PMCID:: PMC7312313

Abstract Article PDF–2.5M

Select item 694875813.

OX40 expression in neutrophils promotes hepatic ischemia/reperfusion injury

Hua Jin, Chunpan Zhang, Chengyang Sun, Xinyan Zhao, Dan Tian, Wen Shi, Yue Tian, Kai Liu, Guangyong Sun, Hufeng Xu, Dong Zhang

JCI Insight. 2019 Nov 1; 4(21): e129736. Published online 2019 Nov 1. doi: 10.1172/jci.insight.129736

PMCID:: PMC6948758

Abstract Article PDF–8.6M

Select item 690443214.

OX40L-JAG1 induced expansion of lineage-stable regulatory T-cells involves non-canonical NF-kB signaling

Prabhakaran Kumar, Swarali Surendra Lele, Vandhana K Ragothaman, Divya Raghunathan, Alan L Epstein, Shigeru Chiba, Bellur S Prabhakar

J Immunol. Author manuscript; available in PMC 2020 Dec 15.

Published in final edited form as: J Immunol. 2019 Dec 15; 203(12): 3225–3236. Published online 2019 Nov 8. doi: 10.4049/jimmunol.1900530

PMCID:: PMC6904432

Abstract Article PDF–1.3M

Select item 676025915.

OX40-enhanced tumor rejection and effector T cell differentiation decreases with age

Carl E. Ruby, Andrew D. Weinberg

J Immunol. Author manuscript; available in PMC 2019 Sep 25.

Published in final edited form as: J Immunol. 2009 Feb 1; 182(3): 1481–1489. doi: 10.4049/jimmunol.182.3.1481

PMCID:: PMC6760259

Abstract Article PDF–1.7M

Select item 631048316.

Anti-drug antibodies to LMB-100 are enhanced by mAbs targeting OX40 and CTLA4 but not by mAbs targeting PD1 or PDL-1

Ronit Mazor, Emily King, Ira Pastan

Cell Immunol. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Cell Immunol. 2018 Dec; 334: 38–41. Published online 2018 Aug 28. doi: 10.1016/j.cellimm.2018.08.016

PMCID:: PMC6310483

Abstract Article PDF–573K

Select item 624905917.

Hippo kinases Mst1 and Mst2 sense and amplify IL-2R–STAT5 signaling in regulatory T cells to establish stable regulatory activity

Hao Shi, Chaohong Liu, Haiyan Tan, Yuxin Li, Thanh-Long M. Nguyen, Yogesh Dhungana, Cliff Guy, Peter Vogel, Geoffrey Neale, Sherri Rankin, Yongqiang Feng, Junmin Peng, Wufan Tao, Hongbo Chi

Immunity. Author manuscript; available in PMC 2019 Nov 20.

Published in final edited form as: Immunity. 2018 Nov 20; 49(5): 899–914.e6. Published online 2018 Nov 6. doi: 10.1016/j.immuni.2018.10.010

PMCID:: PMC6249059

Abstract Article PDF–3.5M

Select item 609519618.

OX40 Costimulation Inhibits Foxp3 Expression and Treg Induction via BATF3-Dependent and Independent Mechanisms

Xiaolong Zhang, Xiang Xiao, Peixiang Lan, Junhui Li, Yaling Dou, Wenhao Chen, Naoto Ishii, Shuqiu Chen, Bo Xia, Kaifu Chen, Elizabeth Taparowsky, Xian C. Li

Cell Rep. Author manuscript; available in PMC 2018 Aug 16.

Published in final edited form as: Cell Rep. 2018 Jul 17; 24(3): 607–618. doi: 10.1016/j.celrep.2018.06.052

PMCID:: PMC6095196

Abstract Article PDF–1.0M

Select item 601511419.

Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells

Timotheus Y.F. Halim, Batika M.J. Rana, Jennifer A. Walker, Bernhard Kerscher, Martin D. Knolle, Helen E. Jolin, Eva M. Serrao, Liora Haim-Vilmovsky, Sarah A. Teichmann, Hans-Reimer Rodewald, Marina Botto, Timothy J. Vyse, Padraic G. Fallon, Zhi Li, David R. Withers, Andrew N.J. McKenzie

Immunity. 2018 Jun 19; 48(6): 1195–1207.e6. doi: 10.1016/j.immuni.2018.05.003

PMCID:: PMC6015114

Abstract Article

Select item 596645320.

Critical role of OX40 in the expansion and survival of CD4 T-cell-derived double-negative T cells

Guangyong Sun, Xiaojing Sun, Wei Li, Kai Liu, Dan Tian, Yiran Dong, Xuelian Sun, Hufeng Xu, Dong Zhang

Cell Death Dis. 2018 Jun; 9(6): 616. Published online 2018 May 23. doi: 10.1038/s41419-018-0659-x

PMCID:: PMC5966453

Abstract Article PDF–2.2M

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