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Select item 113013431.

SENP3 sensitizes macrophages to ferroptosis via de-SUMOylation of FSP1

Xuelian Chen, Jizhuang Wang, Peilang Yang, Hsin-Ying Liu, Shan Zhong, Chenghao Lu, Min Gao, Dan Liu, Jie Zhang, Jiaqiang Wang, Shan Ma, Wenao Wang, Hanting Zhu, Xiong Zhang, Yan Liu

Redox Biol. 2024 Sep; 75: 103267. Published online 2024 Jul 14. doi: 10.1016/j.redox.2024.103267

PMCID:: PMC11301343

Abstract Article PDF–19M

Select item 110215052.

METTL14 downregulation drives S100A4⁺ monocyte-derived macrophages via MyD88/NF-κB pathway to promote MAFLD progression

Yue-fan Wang, Wen-li Zhang, Zhi-xuan Li, Yue Liu, Jian Tan, Hao-zan Yin, Zhi-chao Zhang, Xian-jie Piao, Min-hao Ruan, Zhi-hui Dai, Si-jie Wang, Chen-yang Mu, Ji-hang Yuan, Shu-han Sun, Hui Liu, Fu Yang

Signal Transduct Target Ther. 2024; 9: 91. Published online 2024 Apr 17. doi: 10.1038/s41392-024-01797-1

PMCID:: PMC11021505

Abstract Article PDF–13M

Select item 108465393.

eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling

Lorraine Eley, Rachel V. Richardson, Ahlam Alqahtani, Bill Chaudhry, Deborah J. Henderson

Dis Model Mech. 2024 Jan 1; 17(1): dmm050265. Published online 2024 Jan 22. doi: 10.1242/dmm.050265

PMCID:: PMC10846539

Abstract Article

Select item 107896334.

A novel mechanoeffector role of fibroblast S100A4 in myofibroblast transdifferentiation and fibrosis

Brian D. Southern, Haiyan Li, Hongxia Mao, James F. Crish, Lisa M. Grove, Rachel G. Scheraga, Sanaa Mansoor, Amanda Reinhardt, Susamma Abraham, Gauravi Deshpande, Alicia Loui, Andrei I. Ivanov, Steven S. Rosenfeld, Anne R. Bresnick, Mitchell A. Olman

J Biol Chem. 2024 Jan; 300(1): 105530. Published online 2023 Dec 10. doi: 10.1016/j.jbc.2023.105530

PMCID:: PMC10789633

Abstract Article PDF–6.7M

Select item 107502735.

S100A4 Is a Key Facilitator of Thoracic Aortic Dissection

Jiajun Shi, Wenjun Yu, Chuan Liang, Hongjie Shi, Dengwei Cao, Yong Ran, Haisen Qiao, Zhe Dong, Jinping Liu

Int J Biol Sci. 2024; 20(1): 29–46. Published online 2024 Jan 1. doi: 10.7150/ijbs.83091

PMCID:: PMC10750273

Abstract Article PDF–13M

Select item 98566866.

Notch Blockade Specifically in Bone Marrow-Derived FSP-1-Positive Cells Ameliorates Renal Fibrosis

Yongdong Wu, Ming Liang, Fengzhang Huang, Owen H. Cheng, Xiaoguang Xiao, Tae Hoon Lee, Luan Truong, Jizhong Cheng

Cells. 2023 Jan; 12(2): 214. Published online 2023 Jan 4. doi: 10.3390/cells12020214

PMCID:: PMC9856686

Abstract Article PDF–4.8M

Select item 89817107.

The significance of serum S100 calcium-binding protein A4 in silicosis

Jing Zhang, Cuifang Yuan, Enhong Li, Yiming Guo, Jie Cui, Heliang Liu, Xiaohui Hao, Lingli Guo

BMC Pulm Med. 2022; 22: 127. Published online 2022 Apr 4. doi: 10.1186/s12890-022-01918-y

PMCID:: PMC8981710

Abstract Article PDF–1.1M

Select item 89473408.

S100A4 Is a Strong Negative Prognostic Marker and Potential Therapeutic Target in Adenocarcinoma of the Stomach and Esophagus

Christoph Treese, Kimberly Hartl, Michelle Pötzsch, Matthias Dahlmann, Moritz von Winterfeld, Erika Berg, Michael Hummel, Lena Timm, Beate Rau, Wolfgang Walther, Severin Daum, Dennis Kobelt, Ulrike Stein

Cells. 2022 Mar; 11(6): 1056. Published online 2022 Mar 21. doi: 10.3390/cells11061056

PMCID:: PMC8947340

Abstract Article PDF–2.9M

Select item 88288779.

Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target

Nourhan Abdelfattah, Parveen Kumar, Caiyi Wang, Jia-Shiun Leu, William F. Flynn, Ruli Gao, David S. Baskin, Kumar Pichumani, Omkar B. Ijare, Stephanie L. Wood, Suzanne Z. Powell, David L. Haviland, Brittany C. Parker Kerrigan, Frederick F. Lang, Sujit S. Prabhu, Kristin M. Huntoon, Wen Jiang, Betty Y. S. Kim, Joshy George, Kyuson Yun

Nat Commun. 2022; 13: 767. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28372-y

PMCID:: PMC8828877

Abstract Article PDF–9.5M

Select item 858182810.

MiR-296-5p ameliorates deep venous thrombosis by inactivating S100A4

Zhichang Pan, Yu Zhang, Chuanyong Li, Yuan Yin, Rui Liu, Guangfeng Zheng, Weijian Fan, Qiang Zhang, Zhenyu Song, Ziyue Guo, Jianjie Rong, Yixin Shen

Exp Biol Med (Maywood) 2021 Nov; 246(21): 2259–2268. Published online 2021 Jun 30. doi: 10.1177/15353702211023034

PMCID:: PMC8581828

Abstract Article PDF–937K

Select item 834176511.

S100A4 Is Critical for a Mouse Model of Allergic Asthma by Impacting Mast Cell Activation

Tongqian Wu, Lan Ma, Xiaoqian Jin, Jingjing He, Ke Chen, Dingshan Zhang, Rui Yuan, Jun Yang, Qin Zhong, Haiyan Zhou, Zou Xiang, Yu Fang

Front Immunol. 2021; 12: 692733. Published online 2021 Jul 22. doi: 10.3389/fimmu.2021.692733

PMCID:: PMC8341765

Abstract Article PDF–3.0M

Select item 829788212.

Constitutive activation of NF-κB inducing kinase (NIK) in the mesenchymal lineage using Osterix (Sp7)- or Fibroblast-specific protein 1 (S100a4)-Cre drives spontaneous soft tissue sarcoma

Jennifer L. Davis, Roman Thaler, Linda Cox, Biancamaria Ricci, Heather M. Zannit, Fei Wan, Roberta Faccio, Amel Dudakovic, Andre J. van Wijnen, Deborah J. Veis

PLoS One. 2021; 16(7): e0254426. Published online 2021 Jul 22. doi: 10.1371/journal.pone.0254426

PMCID:: PMC8297882

Abstract Article PDF–3.6M

Select item 821522513.

Adamts18 modulates the development of the aortic arch and common carotid artery

Shuai Ye, Ning Yang, Tiantian Lu, Taojing Wu, Liya Wang, Yi-Hsuan Pan, Xiaohua Cao, Xiaobing Yuan, Thomas Wisniewski, Suying Dang, Wei Zhang

iScience. 2021 Jun 25; 24(6): 102672. Published online 2021 May 31. doi: 10.1016/j.isci.2021.102672

PMCID:: PMC8215225

Abstract Article PDF–8.9M

Select item 819644114.

Targeting S100A4 with niclosamide attenuates inflammatory and profibrotic pathways in models of amyotrophic lateral sclerosis

Martina Milani, Eleonora Mammarella, Simona Rossi, Chiara Miele, Serena Lattante, Mario Sabatelli, Mauro Cozzolino, Nadia D’Ambrosi, Savina Apolloni

J Neuroinflammation. 2021; 18: 132. Published online 2021 Jun 12. doi: 10.1186/s12974-021-02184-1

PMCID:: PMC8196441

Abstract Article PDF–3.2M

Select item 786802615.

The role of S100A4 for bone metastasis in prostate cancer cells

Bongjun Kim, Suhan Jung, Haemin Kim, Jun-Oh Kwon, Min-Kyoung Song, Min Kyung Kim, Hyung Joon Kim, Hong-Hee Kim

BMC Cancer. 2021; 21: 137. Published online 2021 Feb 6. doi: 10.1186/s12885-021-07850-4

PMCID:: PMC7868026

Abstract Article PDF–5.3M

Select item 783841816.

Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract

Rupalatha Maddala, Junyuan Gao, Richard T. Mathias, Tylor R. Lewis, Vadim Y. Arshavsky, Adriana Levine, Jonathan M. Backer, Anne R. Bresnick, Ponugoti V. Rao

Sci Rep. 2021; 11: 2203. Published online 2021 Jan 26. doi: 10.1038/s41598-021-81611-y

PMCID:: PMC7838418

Abstract Article PDF–6.5M

Select item 781213017.

Fsp1 cardiac embryonic expression delineates atrioventricular endocardial cushion, coronary venous and lymphatic valve development

Sara Cano‐Ballesteros, Paul Palmquist‐Gomes, Ernesto Marín‐Sedeño, Juan Antonio Guadix, José María Pérez‐Pomares

J Anat. 2021 Feb; 238(2): 508–514. Published online 2020 Sep 13. doi: 10.1111/joa.13306

PMCID:: PMC7812130

Abstract Article PDF–1.9M

Select item 776961418.

S100A4+ macrophages facilitate zika virus invasion and persistence in the seminiferous tubules via interferon-gamma mediation

Wei Yang, Yan-Hua Wu, Shuang-Qing Liu, Zi-Yang Sheng, Zi-Da Zhen, Rui-Qi Gao, Xiao-Yun Cui, Dong-Ying Fan, Zhi-Hai Qin, Ai-Hua Zheng, Pei-Gang Wang, Jing An

PLoS Pathog. 2020 Dec; 16(12): e1009019. Published online 2020 Dec 14. doi: 10.1371/journal.ppat.1009019

PMCID:: PMC7769614

Abstract Article PDF–8.6M

Select item 755636019.

Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

Lin Wu, Kate E.R. Hollinshead, Yuhan Hao, Christy Au, Lina Kroehling, Charles Ng, Woan-Yu Lin, Dayi Li, Hernandez Moura Silva, Jong Shin, Juan J. Lafaille, Richard Possemato, Michael E. Pacold, Thales Papagiannakopoulos, Alec C. Kimmelman, Rahul Satija, Dan R. Littman

Cell. Author manuscript; available in PMC 2021 Aug 6.

Published in final edited form as: Cell. 2020 Aug 6; 182(3): 641–654.e20. Published online 2020 Jul 1. doi: 10.1016/j.cell.2020.06.014

PMCID:: PMC7556360

Abstract Article PDF–2.2M

Select item 737117820.

Keratinocyte-specific deletion of SHARPIN induces atopic dermatitis-like inflammation in mice

John P. Sundberg, C. Herbert Pratt, Leslie P. Goodwin, Kathleen A. Silva, Victoria E. Kennedy, Christopher S. Potter, Anisa Dunham, Beth A. Sundberg, Harm HogenEsch

PLoS One. 2020; 15(7): e0235295. Published online 2020 Jul 20. doi: 10.1371/journal.pone.0235295