PMC Links for GEO Profiles (Select 1673002) - PMC

Cynthia Weigel, Melissa A. Maczis, Elisa N. D. Palladino, Christopher D. Green, Michael Maceyka, Chunqing Guo, Xiang-Yang Wang, Mikhail G. Dozmorov, Sheldon Milstien, Sarah Spiegel

Cancer Res. Author manuscript; available in PMC 2023 Aug 15.

Published in final edited form as: Cancer Res. 2023 Feb 15; 83(4): 553–567. doi: 10.1158/0008-5472.CAN-22-1638

PMCID:: PMC9931683

Abstract Article PDF–3.5M

Select item 98734764.

Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney

Shinji Tanaka, Shuqiu Zheng, Yugesh Kharel, Russell G. Fritzemeier, Tao Huang, Daniel Foster, Nabin Poudel, Eibhlin Goggins, Yusuke Yamaoka, Kinga P. Rudnicka, Jonathan E. Lipsey, Hope V. Radel, Sophia M. Ryuh, Tsuyoshi Inoue, Junlan Yao, Diane L. Rosin, Susan R. Schwab, Webster L. Santos, Kevin R. Lynch, Mark D. Okusa

Sci Transl Med. Author manuscript; available in PMC 2023 Jan 24.

Published in final edited form as: Sci Transl Med. 2022 Aug 17; 14(658): eabj2681. Published online 2022 Aug 17. doi: 10.1126/scitranslmed.abj2681

PMCID:: PMC9873476

Abstract Article PDF–2.6M

Select item 96718915.

SphK-produced S1P in somatic cells is indispensable for LH-EGFR signaling-induced mouse oocyte maturation

Feifei Yuan, Xiaoqiong Hao, Yanying Cui, FuXin Huang, Xiaodan Zhang, Yanli Sun, Tiantian Hao, Zhijuan Wang, Wei Xia, Youqiang Su, Meijia Zhang

Cell Death Dis. 2022 Nov; 13(11): 963. Published online 2022 Nov 17. doi: 10.1038/s41419-022-05415-2

PMCID:: PMC9671891

Abstract Article PDF–6.2M

Select item 96572116.

The Impact of Sphingosine Kinases on Inflammation-Induced Cytokine Release and Vascular Endothelial Barrier Integrity

Andreas V. Thuy, Christina-Maria Reimann, Anke C. Ziegler, Markus H. Gräler

Int J Mol Sci. 2022 Nov; 23(21): 12848. Published online 2022 Oct 25. doi: 10.3390/ijms232112848

PMCID:: PMC9657211

Abstract Article PDF–1.6M

Select item 93947717.

Loss of sphingosine kinase 2 protects against cisplatin-induced kidney injury

Dengpiao Xie, Gaizun Hu, Chaoling Chen, Fereshteh Ahmadinejad, Weili Wang, Pin-Lan Li, David A. Gewirtz, Ningjun Li

Am J Physiol Renal Physiol. 2022 Sep 1; 323(3): F322–F334. Published online 2022 Jul 13. doi: 10.1152/ajprenal.00229.2021

PMCID:: PMC9394771

Abstract Article

Select item 91808118.

Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells

Redona Hafizi, Faik Imeri, Bisera Stepanovska Tanturovska, Roxana Manaila, Stephanie Schwalm, Sandra Trautmann, Roland H. Wenger, Josef Pfeilschifter, Andrea Huwiler

Int J Mol Sci. 2022 Jun; 23(11): 5882. Published online 2022 May 24. doi: 10.3390/ijms23115882

PMCID:: PMC9180811

Abstract Article PDF–2.7M

Select item 89047889.

Sphk2 deletion is involved in structural abnormalities and Th17 response but does not aggravate colon inflammation induced by sub-chronic stress

David Martín-Hernández, Irene L. Gutiérrez, Marta González-Prieto, Karina S. MacDowell, Javier Robledo-Montaña, Hiram Tendilla-Beltrán, Natalia Calleja-Rodríguez, Álvaro G. Bris, Cristina Ulecia-Morón, Beatriz Moreno, Javier R. Caso, Borja García-Bueno, Sandra Rodrigues-Mascarenhas, Ignacio Marín-Jiménez, Juan Carlos Leza, Luis Menchén

Sci Rep. 2022; 12: 4073. Published online 2022 Mar 8. doi: 10.1038/s41598-022-08011-8

PMCID:: PMC8904788

Abstract Article PDF–9.9M

Select item 872177310.

Arachnoid membrane as a source of sphingosine-1-phosphate that regulates mouse middle cerebral artery tone

Francesc Jiménez-Altayó, Julia Marzi, María Galan, Ana Paula Dantas, Marisa Ortega, Santiago Rojas, Gustavo Egea, Katja Schenke-Layland, Elena Jiménez-Xarrié, Anna M Planas

J Cereb Blood Flow Metab. 2022 Jan; 42(1): 162–174. Published online 2021 Sep 2. doi: 10.1177/0271678X211033362

PMCID:: PMC8721773

Abstract Article PDF–1.4M

Select item 849615511.

Deletion of Sphingosine 1‐Phosphate receptor 1 in cardiomyocytes during development leads to abnormal ventricular conduction and fibrosis

Ryan Jorgensen, Meghna Katta, Jayne Wolfe, Desiree F. Leach, Bianca Lavelle, Jerold Chun, Lisa D. Wilsbacher

Physiol Rep. 2021 Oct; 9(19): e15060. Published online 2021 Oct 7. doi: 10.14814/phy2.15060

PMCID:: PMC8496155

Abstract Article PDF–2.8M

Select item 809539012.

An Unanticipated Role for Sphingosine Kinase-2 in Bone and in the Anabolic Effect of Parathyroid Hormone

Joanne M Walker, Gang-Qing Yao, Edwin Siu, Meiling Zhu, Ben-hua Sun, Christine Simpson, Karl L Insogna

Endocrinology. 2021 May; 162(5): bqab042. Published online 2021 Feb 26. doi: 10.1210/endocr/bqab042

PMCID:: PMC8095390

Abstract Article

Select item 768574713.

Sphingosine kinase 2 restricts T cell immunopathology but permits viral persistence

Caleb J. Studstill, Curtis J. Pritzl, Young-Jin Seo, Dae Young Kim, Chuan Xia, Jennifer J. Wolf, Ravi Nistala, Madhuvanthi Vijayan, Yong-Bin Cho, Kyung Won Kang, Sang-Myeong Lee, Bumsuk Hahm

J Clin Invest. 2020 Dec 1; 130(12): 6523–6538. Published online 2020 Nov 9. doi: 10.1172/JCI125297

PMCID:: PMC7685747

Abstract Article PDF–6.7M

Select item 753387114.

Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2

Gulibositan Aji, Yu Huang, Mei Li Ng, Wei Wang, Tian Lan, Min Li, Yufei Li, Qi Chen, Rui Li, Sishan Yan, Collin Tran, James G. Burchfield, Timothy A. Couttas, Jinbiao Chen, Long Hoa Chung, Da Liu, Carol Wadham, Philip J. Hogg, Xin Gao, Mathew A. Vadas, Jennifer R. Gamble, Anthony S. Don, Pu Xia, Yanfei Qi

Proc Natl Acad Sci U S A. 2020 Sep 29; 117(39): 24434–24442. Published online 2020 Sep 11. doi: 10.1073/pnas.2007856117

PMCID:: PMC7533871

Abstract Article PDF–1.3M

Select item 742581715.

Sphingosine Kinase-1 is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina.

Joseph L. Wilkerson, Megan A. Stiles, Jami M. Gurley, Richard C. Grambergs, Xiaowu Gu, Michael H. Elliott, Richard L. Proia, Nawajes A. Mandal

Mol Neurobiol. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Mol Neurobiol. 2019 Oct; 56(10): 7188–7207. Published online 2019 Apr 17. doi: 10.1007/s12035-019-1599-x

PMCID:: PMC7425817

Abstract Article PDF–1.8M

Select item 741599116.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 734486117.

A Novel Function of Sphingosine Kinase 2 in the Metabolism of Sphinga-4,14-Diene Lipids

Timothy Andrew Couttas, Yepy Hardi Rustam, Huitong Song, Yanfei Qi, Jonathan David Teo, Jinbiao Chen, Gavin Edmund Reid, Anthony Simon Don

Metabolites. 2020 Jun; 10(6): 236. Published online 2020 Jun 8. doi: 10.3390/metabo10060236

PMCID:: PMC7344861

Abstract Article PDF–2.2M

Select item 717005018.

SPHK2-Generated S1P in CD11b⁺ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages

Jagdish C. Joshi, Bhagwati Joshi, Ian Rochford, Sheikh Rayees, Md Zahid Akhter, Sukriti Baweja, Koteshwara Rao Chava, Mohammad Tauseef, Hazem Abdelkarim, Viswanathan Natarajan, Vadim Gaponenko, Dolly Mehta

Cell Rep. Author manuscript; available in PMC 2020 Apr 20.

Published in final edited form as: Cell Rep. 2020 Mar 24; 30(12): 4096–4109.e5. doi: 10.1016/j.celrep.2020.02.112

PMCID:: PMC7170050

Abstract Article PDF–1.9M

Select item 705986619.

Mechanism of sphingosine 1-phosphate clearance from blood

Yugesh Kharel, Tao Huang, Anita Salamon, Thurl E. Harris, Webster L. Santos, Kevin R. Lynch

Biochem J. 2020 Mar 13; 477(5): 925–935. Prepublished online 2020 Feb 17. Published online 2020 Mar 6. doi: 10.1042/BCJ20190730

Correction in:: Biochem J. 2023 Dec 20; 480(24): 2059–2060.

PMCID:: PMC7059866

Abstract Article PDF–1.4M

Select item 705400120.

Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

Eric Engelbrecht, Michel V Levesque, Liqun He, Michael Vanlandewijck, Anja Nitzsche, Hira Niazi, Andrew Kuo, Sasha A Singh, Masanori Aikawa, Kristina Holton, Richard L Proia, Mari Kono, William T Pu, Eric Camerer, Christer Betsholtz, Timothy Hla

eLife. 2020; 9: e52690. Published online 2020 Feb 24. doi: 10.7554/eLife.52690

PMCID:: PMC7054001

Abstract Article PDF–17M

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