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Select item 114767201.

Understanding the Dosage-Dependent Role of Dicer1 in Thyroid Tumorigenesis

María Rojo-Pardillo, Ludivine Godefroid, Geneviève Dom, Anne Lefort, Frederick Libert, Bernard Robaye, Carine Maenhaut

Int J Mol Sci. 2024 Oct; 25(19): 10701. Published online 2024 Oct 4. doi: 10.3390/ijms251910701

PMCID:: PMC11476720

Abstract Article PDF–5.1M

Select item 114678602.

Comparative Biochemical Studies of Disease-Associated Human Dicer Mutations on Processing of a Pre-microRNA and snoRNA

Rachel M. Torrez, Shruti Nagaraja, Arya Menon, Louise Chang, Melanie D. Ohi, Amanda L. Garner

Biochemistry. Author manuscript; available in PMC 2024 Oct 11.

Published in final edited form as: Biochemistry. 2023 Jun 6; 62(11): 1725–1734. Published online 2023 May 2. doi: 10.1021/acs.biochem.2c00687

PMCID:: PMC11467860

Abstract Article PDF–1.4M

Select item 112379303.

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein

Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo

J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390

PMCID:: PMC11237930

Abstract Article PDF–3.8M

Select item 112099354.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111805045.

Prevalence, Molecular Landscape, and Clinical Impact of DICER1 and DGCR8 Mutated Follicular-Patterned Thyroid Nodules

Vincenzo Condello, Anello M Poma, Elisabetta Macerola, Paola Vignali, Johan O Paulsson, Jan Zedenius, Fulvio Basolo, C Christofer Juhlin

J Clin Endocrinol Metab. 2024 Jul; 109(7): 1733–1744. Published online 2024 Jan 22. doi: 10.1210/clinem/dgae034

PMCID:: PMC11180504

Abstract Article

Select item 111799736.

Prevalence of lung cysts in adolescents and adults with a germline DICER1 pathogenic/likely pathogenic variant: A report from the National Institutes of Health and International Pleuropulmonary Blastoma/DICER1 Registry

Alexander T. Nelson, Lauren M. Vasta, Dave Watson, Jung Kim, Anne K. Harris, Ana F. Best, Laura A. Harney, Ann Garrity Carr, Nicole Frederickson, Louis P. Dehner, Christian P. Kratz, Kelly N. Hagedorn, William A. Mize, Alexander Ling, Yoav H. Messinger, D. Ashley Hill, Kris Ann P. Schultz, Douglas R. Stewart

Thorax. Author manuscript; available in PMC 2024 Jun 16.

Published in final edited form as: Thorax. 2024 Jun 14; 79(7): 644–651. Published online 2024 Jun 14. doi: 10.1136/thorax-2023-221024

PMCID:: PMC11179973

Abstract Article PDF–1007K

Select item 111077387.

Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair

Farima Zahedi, Maliheh Nazari-Jahantigh, Zhe Zhou, Pallavi Subramanian, Yuanyuan Wei, Jochen Grommes, Stefan Offermanns, Sabine Steffens, Christian Weber, Andreas Schober

Cell Mol Life Sci. 2017 Jan; 74(2): 359–372. Published online 2016 Sep 12. doi: 10.1007/s00018-016-2349-0

PMCID:: PMC11107738

Abstract Article PDF–2.7M

Select item 109889248.

Clinicopathological analysis of 22 Müllerian adenosarcomas and the sequencing of DICER1 mutation

Xiaohong Yao, Wei Wang, Ying He

Diagn Pathol. 2024; 19: 56. Published online 2024 Apr 3. doi: 10.1186/s13000-024-01477-2

PMCID:: PMC10988924

Abstract Article PDF–1.4M

Select item 109480419.

Prevalence of DICER1 variants in large multinodular goiter: thyroid function, clinical and imaging characteristics

Lara Judith Cabral Miranda, Débora L. S. Danilovic, Felipe Augusto Brasileiro Vanderlei, Marcos Roberto Tavares, Nicolau Lima, Neto, Rosalinda Yossie Asato de Camargo, Suemi Marui

Arch Endocrinol Metab. 2024; 68: e230030. Published online 2024 Feb 8. doi: 10.20945/2359-4292-2023-0030

PMCID:: PMC10948041

Abstract Article PDF–252K

Select item 1094246710.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 1089975011.

Two-motif model illuminates DICER cleavage preferences

Cong Truc Le, Trung Duc Nguyen, Tuan Anh Nguyen

Nucleic Acids Res. 2024 Feb 28; 52(4): 1860–1877. Published online 2024 Jan 3. doi: 10.1093/nar/gkad1186

PMCID:: PMC10899750

Abstract Article PDF–2.5M

Select item 1086095312.

Intronic Germline DICER1 Variants in Patients With Sertoli-Leydig Cell Tumor

Claudette R. Fraire, Paige R. Mallinger, Jessica N. Hatton, Jung Kim, David S. Dickens, Peter A. Argenta, Samuel Milanovich, Taylor Hartshorne, David J. Carey, Jeremy S. Haley, Gretchen Urban, Jeon Lee, D. Ashley Hill, Douglas R. Stewart, Kris Ann P. Schultz, Kenneth S. Chen

JCO Precis Oncol. 2023; 7: e2300189. Published online 2023 Oct 26. doi: 10.1200/PO.23.00189

PMCID:: PMC10860953

Abstract Article PDF–864K

Select item 1080699113.

Substrate promiscuity of Dicer toward precursors of the let-7 family and their 3′-end modifications

Gunjan Dadhwal, Hebatallah Samy, Jonathan Bouvette, Fatima El-Azzouzi, Pierre Dagenais, Pascale Legault

Cell Mol Life Sci. 2024 Dec; 81(1): 53. Published online 2024 Jan 23. doi: 10.1007/s00018-023-05090-2

PMCID:: PMC10806991

Abstract Article PDF–2.4M

Select item 1077561514.

DiCleave: a deep learning model for predicting human Dicer cleavage sites

Lixuan Mu, Jiangning Song, Tatsuya Akutsu, Tomoya Mori

BMC Bioinformatics. 2024; 25: 13. Published online 2024 Jan 9. doi: 10.1186/s12859-024-05638-4

PMCID:: PMC10775615

Abstract Article PDF–2.2M

Select item 1076620715.

USP7 reduces the level of nuclear DICER, impairing DNA damage response and promoting cancer progression

Xiaojia Liu, Runhui Lu, Qianqian Yang, Jianfeng He, Caihu Huang, Yingting Cao, Zihan Zhou, Jiayi Huang, Lian Li, Ran Chen, Yanli Wang, Jian Huang, Ruiyu Xie, Xian Zhao, Jianxiu Yu

Mol Oncol. 2024 Jan; 18(1): 170–189. Published online 2023 Nov 2. doi: 10.1002/1878-0261.13543

PMCID:: PMC10766207

Abstract Article PDF–2.7M

Select item 1071335016.

Specifications of the ACMG/AMP Variant Classification Guidelines for Germline DICER1 Variant Curation

Jessica N. Hatton, Megan N. Frone, Hannah C. Cox, Stephanie B. Crowley, Susan Hiraki, Noriko N. Yokoyama, Noura S. Abul-Husn, James F. Amatruda, Michael J. Anderson, Xavier Bofill-De Ros, Ann G. Carr, Elizabeth C. Chao, Kenneth S. Chen, Shuo Gu, Cecilia Higgs, Jerry Machado, Deborah Ritter, Kris Ann Schultz, Emily R. Soper, Mona K. Wu, Jessica L. Mester, Jung Kim, William D. Foulkes, Leora Witkowski, Douglas R. Stewart

Hum Mutat. Author manuscript; available in PMC 2023 Dec 11.

Published in final edited form as: Hum Mutat. 2023; 2023: 9537832. Published online 2023 Mar 29. doi: 10.1155/2023/9537832

PMCID:: PMC10713350

Abstract Article PDF–563K

Select item 1058514417.

Genomic and transcriptomic analyses of thyroid cancers identify DICER1 somatic mutations in adult follicular-patterned RAS-like tumors

Emanuela Minna, Andrea Devecchi, Federico Pistore, Biagio Paolini, Giuseppe Mauro, Donata Alda Penso, Sonia Pagliardini, Adele Busico, Giancarlo Pruneri, Loris De Cecco, Maria Grazia Borrello, Marialuisa Sensi, Angela Greco

Front Endocrinol (Lausanne) 2023; 14: 1267499. Published online 2023 Oct 5. doi: 10.3389/fendo.2023.1267499

PMCID:: PMC10585144

Abstract Article PDF–1.3M

Select item 1054183518.

Reclassification of two germline DICER1 splicing variants leads to DICER1 syndrome diagnosis

Maria Apellaniz-Ruiz, Nelly Sabbaghian, Anne-Laure Chong, Leanne de Kock, Semra Cetinkaya, Elvan Bayramoğlu, Winand N. M. Dinjens, W. Glenn McCluggage, Anja Wagner, Aslihan Arasli Yilmaz, William D. Foulkes

Fam Cancer. 2023; 22(4): 487–493. Published online 2023 May 30. doi: 10.1007/s10689-023-00336-1

PMCID:: PMC10541835

Abstract Article PDF–1.3M

Select item 1047021819.

Epstein–Barr virus microRNA miR-BART2-5p accelerates nasopharyngeal carcinoma metastasis by suppressing RNase Ⅲ endonuclease DICER1

Yangge Wu, Xiaoyue Zhang, Can Liu, Zhengshuo Li, Yuqing Wen, Run Zheng, Chenxiao Xu, Junrui Tian, Lingyu Wei, Jia Wang, Qun Yan, Xiang Zheng, Jian Ma

J Biol Chem. 2023 Sep; 299(9): 105082. Published online 2023 Jul 24. doi: 10.1016/j.jbc.2023.105082

PMCID:: PMC10470218

Abstract Article PDF–5.5M

Select item 1046961220.

High-sensitivity profiling of SARS-CoV-2 noncoding region–host protein interactome reveals the potential regulatory role of negative-sense viral RNA

Liuyiqi Jiang, Mu Xiao, Qing-Qing Liao, Luqian Zheng, Chunyan Li, Yuemei Liu, Bing Yang, Aiming Ren, Chao Jiang, Xin-Hua Feng

mSystems. 2023 Jul-Aug; 8(4): e00135-23. Published online 2023 Jun 14. doi: 10.1128/msystems.00135-23

PMCID:: PMC10469612

Abstract Article PDF–4.0M

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