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Select item 111588401.

BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin

Hyun Jeong Shim, Joo Young Yun, Jun Eul Hwang, Woo Kyun Bae, Sang Hee Cho, Ji Hee Lee, Hee Nam Kim, Min Ho Shin, Sun Seog Kweon, Jae Hyuk Lee, Hyeoung Joon Kim, Ik Joo Chung

Cancer Sci. 2010 May; 101(5): 1247–1254. Published online 2010 Mar 12. doi: 10.1111/j.1349-7006.2010.01514.x

PMCID:: PMC11158840

Abstract Article PDF–215K

Select item 108832802.

Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation

Chop Yan Lee, Dalmira Hubrich, Julia K Varga, Christian Schäfer, Mareen Welzel, Eric Schumbera, Milena Djokic, Joelle M Strom, Jonas Schönfeld, Johanna L Geist, Feyza Polat, Toby J Gibson, Claudia Isabelle Keller Valsecchi, Manjeet Kumar, Ora Schueler-Furman, Katja Luck

Mol Syst Biol. 2024 Feb; 20(2): 75–97. Published online 2024 Jan 15. doi: 10.1038/s44320-023-00005-6

PMCID:: PMC10883280

Abstract Article PDF–3.4M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102149994.

APTX acts in DNA double-strand break repair in a manner distinct from XRCC4

Rikiya Imamura, Mizuki Saito, Mikio Shimada, Junya Kobayashi, Masamichi Ishiai, Yoshihisa Matsumoto

J Radiat Res. 2023 May; 64(3): 485–495. Published online 2023 Mar 20. doi: 10.1093/jrr/rrad007

PMCID:: PMC10214999

Abstract Article PDF–1.1M

Select item 99213125.

Systematic analysis identifies XRCC4 as a potential immunological and prognostic biomarker associated with pan-cancer

Yang Yu, Yanyan Sun, Zhaoxian Li, Jiang Li, Dazhi Tian

BMC Bioinformatics. 2023; 24: 44. Published online 2023 Feb 10. doi: 10.1186/s12859-023-05165-8

PMCID:: PMC9921312

Abstract Article PDF–5.5M

Select item 98122526.

Genome stability-related lncRNA ZFPM2-AS1 promotes tumor progression via miR-3065-5p/XRCC4 in hepatocellular carcinoma

Jie Liu, Hao Zhang, Peng Xia, Yimin Zhu, Kequan Xu, Zhisu Liu, Yufeng Yuan

Int J Oncol. 2023 Feb; 62(2): 19. Published online 2022 Dec 14. doi: 10.3892/ijo.2022.5467

PMCID:: PMC9812252

Abstract Article PDF–16M

Select item 93434557.

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis

Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi

Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y

PMCID:: PMC9343455

Abstract Article PDF–3.7M

Select item 92792858.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 903609210.

Tumor suppressor BAP1 nuclear import is governed by transportin-1

Tzu-Jing Yang, Tian-Neng Li, Rih-Sheng Huang, Max Yu-Chen Pan, Shu-Yu Lin, Steven Lin, Kuen-Phon Wu, Lily Hui-Ching Wang, Shang-Te Danny Hsu

J Cell Biol. 2022 Jun 6; 221(6): e202201094. Published online 2022 Apr 21. doi: 10.1083/jcb.202201094

PMCID:: PMC9036092

Abstract Article PDF–4.0M

Select item 900639611.

Cryo-EM of NHEJ supercomplexes provides insights into DNA repair

Amanda K. Chaplin, Steven W. Hardwick, Antonia Kefala Stavridi, Christopher J. Buehl, Noah J. Goff, Virginie Ropars, Shikang Liang, Taiana Maia De Oliveira, Dimitri Y. Chirgadze, Katheryn Meek, Jean-Baptiste Charbonnier, Tom L. Blundell

Mol Cell. Author manuscript; available in PMC 2022 Aug 19.

Published in final edited form as: Mol Cell. 2021 Aug 19; 81(16): 3400–3409.e3. Published online 2021 Aug 4. doi: 10.1016/j.molcel.2021.07.005

PMCID:: PMC9006396

Abstract Article PDF–3.0M

Select item 877611612.

XRCC4 and MRE11 Roles and Transcriptional Response to Repair of TALEN-Induced Double-Strand DNA Breaks

Ronald Benjamin, Atoshi Banerjee, Xiaogang Wu, Corey Geurink, Lindsay Buczek, Danielle Eames, Sara G. Trimidal, Janice M. Pluth, Martin R. Schiller

Int J Mol Sci. 2022 Jan; 23(2): 593. Published online 2022 Jan 6. doi: 10.3390/ijms23020593

PMCID:: PMC8776116

Abstract Article PDF–3.3M

Select item 856534313.

USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing

Jae Jin Kim, Seo Yun Lee, Yiseul Hwang, Soyeon Kim, Jee Min Chung, Sangwook Park, Junghyun Yoon, Hansol Yun, Jae-Hoon Ji, Sunyoung Chae, Hyeseong Cho, Chan Gil Kim, Ted M Dawson, Hongtae Kim, Valina L Dawson, Ho Chul Kang

Nucleic Acids Res. 2021 Nov 8; 49(19): 11083–11102. Published online 2021 Oct 6. doi: 10.1093/nar/gkab892

PMCID:: PMC8565343

Abstract Article PDF–11M

Select item 837641114.

X‐ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double‐strand break repair impacting cell and cancer biology

Michal Hammel, John A. Tainer

Protein Sci. 2021 Sep; 30(9): 1735–1756. Published online 2021 Jun 5. doi: 10.1002/pro.4133

PMCID:: PMC8376411

Abstract Article PDF–4.8M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 812766916.

Functional analysis of XRCC4 mutations in reported microcephaly and growth defect patients in terms of radiosensitivity

Anie Day D C Asa, Rujira Wanotayan, Mukesh Kumar Sharma, Kaima Tsukada, Mikio Shimada, Yoshihisa Matsumoto

J Radiat Res. 2021 May; 62(3): 380–389. Published online 2021 Apr 12. doi: 10.1093/jrr/rrab016

PMCID:: PMC8127669

Abstract Article PDF–755K

Select item 804180317.

Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling

Guijie Guo, Ming Gao, Xiaochen Gao, Bibo Zhu, Jinzhou Huang, Xinyi Tu, Wootae Kim, Fei Zhao, Qin Zhou, Shouhai Zhu, Zheming Wu, Yuanliang Yan, Yong Zhang, Xiangyu Zeng, Qian Zhu, Ping Yin, Kuntian Luo, Jie Sun, Min Deng, Zhenkun Lou

Nat Commun. 2021; 12: 2187. Published online 2021 Apr 12. doi: 10.1038/s41467-021-22484-7

PMCID:: PMC8041803

Abstract Article PDF–3.7M

Select item 752544118.

Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion

Hyeon Gyu Seo, Han Byeol Kim, Ji Young Yoon, Tae Hyun Kweon, Yun Soo Park, Jingu Kang, Jinwoo Jung, SeongJin Son, Eugene C. Yi, Tae Ho Lee, Won Ho Yang, Jin Won Cho

Cell Death Dis. 2020 Sep; 11(9): 815. Published online 2020 Sep 29. doi: 10.1038/s41419-020-02999-5

PMCID:: PMC7525441

Abstract Article PDF–3.7M

Select item 746827919.

Inhibition of non-homologous end joining of gamma ray-induced DNA double-strand breaks by cAMP signaling in lung cancer cells

Sung-Eun Noh, Yong-Sung Juhnn

Sci Rep. 2020; 10: 14455. Published online 2020 Sep 2. doi: 10.1038/s41598-020-71522-9

PMCID:: PMC7468279

Abstract Article PDF–5.1M

Select item 742732720.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

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