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Select item 114030621.

Conditional deletion of CEACAM1 in hepatic stellate cells causes their activation

Harrison T. Muturi, Hilda E. Ghadieh, Suman Asalla, Sumona G. Lester, Getachew D. Belew, Sobia Zaidi, Raziyeh Abdolahipour, Abhishek P. Shrestha, Agnes O. Portuphy, Hannah L. Stankus, Raghd Abu Helal, Stefaan Verhulst, Sergio Duarte, Ali Zarrinpar, Leo A. van Grunsven, Scott L. Friedman, Robert F. Schwabe, Terry D. Hinds, Jr., Sivarajan Kumarasamy, Sonia M. Najjar

Mol Metab. 2024 Oct; 88: 102010. Published online 2024 Aug 19. doi: 10.1016/j.molmet.2024.102010

PMCID:: PMC11403062

Abstract Article PDF–3.7M

Select item 111642452.

Alternative splicing of CEACAM1 by Hypoxia-Inducible Factor–1α enhances tolerance to hepatic ischemia in mice and humans

Kenneth J. Dery, Hidenobu Kojima, Shoichi Kageyama, Kentaro Kadono, Hirofumi Hirao, Brian Cheng, Yuan Zhai, Douglas G. Farmer, Fady M. Kaldas, Xiaoyi Yuan, Holger K. Eltzschiasg, Jerzy W. Kupiec-Weglinski

Sci Transl Med. Author manuscript; available in PMC 2024 Jun 10.

Published in final edited form as: Sci Transl Med. 2023 Aug 2; 15(707): eadf2059. Published online 2023 Aug 2. doi: 10.1126/scitranslmed.adf2059

PMCID:: PMC11164245

Abstract Article PDF–2.9M

Select item 111530183.

Loss of CEACAM1 in hepatocytes causes hepatic fibrosis

Sobia Zaidi, Suman Asalla, Harrison T. Muturi, Lucia Russo, Raziyeh Abdolahipour, Getachew Debas Belew, Maria Benitez Iglesias, Mary Feraudo, Lensay Leon, Enoch Kuo, Xiuli Liu, Sivarajan Kumarasamy, Hilda E. Ghadieh, Cara Gatto-Weis, Ali Zarrinpar, Sergio Duarte, Sonia M. Najjar

Eur J Clin Invest. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Eur J Clin Invest. 2024 Jul; 54(7): e14177. Published online 2024 Feb 21. doi: 10.1111/eci.14177

PMCID:: PMC11153018

Abstract Article PDF–1.9M

Select item 110309264.

Systemic dysregulation of CEACAM1 in melanoma patients

Gal Markel, Rona Ortenberg, Rachel Seidman, Sivan Sapoznik, Nira Koren-Morag, Michal J. Besser, Jair Bar, Ronnie Shapira, Adva Kubi, Gil Nardini, Ariel Tessone, Avraham J. Treves, Eyal Winkler, Arie Orenstein, Jacob Schachter

Cancer Immunol Immunother. 2010 Feb; 59(2): 215–230. Published online 2009 Jul 25. doi: 10.1007/s00262-009-0740-5

PMCID:: PMC11030926

Abstract Article PDF–713K

Select item 107042405.

The role of carcinoembryonic antigen-related cell adhesion molecule 1 in cancer

Lisa Götz, Uwe Rueckschloss, Gözde Balk, Verena Pfeiffer, Süleyman Ergün, Florian Kleefeldt

Front Immunol. 2023; 14: 1295232. Published online 2023 Nov 24. doi: 10.3389/fimmu.2023.1295232

PMCID:: PMC10704240

Abstract Article PDF–1.3M

Select item 101191776.

Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis

Erin A. Catton, Daniel A. Bonsor, Carolina Herrera, Margaretha Stålhammar-Carlemalm, Mykola Lyndin, Claire E. Turner, Jo Soden, Jos A. G. van Strijp, Bernhard B. Singer, Nina M. van Sorge, Gunnar Lindahl, Alex J. McCarthy

Nat Commun. 2023; 14: 2275. Published online 2023 Apr 20. doi: 10.1038/s41467-023-37732-1

Correction in:: Nat Commun. 2023; 14: 2675.

PMCID:: PMC10119177

Abstract Article PDF–2.4M

Select item 99951287.

NLR family CARD domain containing 5 promotes hypoxia-induced cancer progress and carboplatin resistance by activating PI3K/AKT via carcinoembryonic antigen related cell adhesion molecule 1 in non-small cell lung cancer

Yu Dong, Tao Xu, Dongfan Li, Hua Guo, Xusheng Du, Guangshun Li, Jiakuan Chen, Bo Wang, Peng Wang, Gang Yu, Xuan Zhao, Ruiqi Xue

Bioengineered. 2022; 13(6): 14413–14425. Published online 2023 Jan 24. doi: 10.1080/21655979.2022.2086375

PMCID:: PMC9995128

Abstract Article PDF–8.4M

Select item 98766858.

CEACAM1 Is a Prognostic Biomarker and Correlated with Immune Cell Infiltration in Clear Cell Renal Cell Carcinoma

Lu Yang, Yun Liu, Boke Zhang, Mengsi Yu, Fen Huang, Jiangzheng Zeng, Yanda Lu, Changcheng Yang

Dis Markers. 2023; 2023: 3606362. Published online 2023 Jan 18. doi: 10.1155/2023/3606362

PMCID:: PMC9876685

Abstract Article PDF–3.1M

Select item 97945749.

Increased CEACAM1 expression on peripheral blood neutrophils in patients with rheumatoid arthritis

Haruki Matsumoto, Yuya Fujita, Michio Onizawa, Kenji Saito, Yuya Sumichika, Shuhei Yoshida, Jumpei Temmoku, Naoki Matsuoka, Makiko Yashiro-Furuya, Tomoyuki Asano, Shuzo Sato, Eiji Suzuki, Takeshi Machida, Hiroshi Watanabe, Kiyoshi Migita

Front Immunol. 2022; 13: 978435. Published online 2022 Dec 14. doi: 10.3389/fimmu.2022.978435

PMCID:: PMC9794574

Abstract Article PDF–1.0M

Select item 976428110.

Glycan Conformation in the Heavily Glycosylated Protein, CEACAM1

Monique J. Rogals, Alexander Eletsky, Chin Huang, Laura C. Morris, Kelley W. Moremen, James H. Prestegard

ACS Chem Biol. 2022 Dec 16; 17(12): 3527–3534. Published online 2022 Nov 23. doi: 10.1021/acschembio.2c00714

PMCID:: PMC9764281

Abstract Article PDF–4.9M

Select item 953088011.

Transfer RNA‐derived fragment 5′tRF‐Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen‐related cell adhesion molecule 1

Dekai Liu, Chengdong Wu, Jingjie Wang, Lufei Zhang, Zhongquan Sun, Shihong Chen, Yuan Ding, Weilin Wang

Cancer Sci. 2022 Oct; 113(10): 3476–3488. Published online 2022 Aug 16. doi: 10.1111/cas.15505

PMCID:: PMC9530880

Abstract Article PDF–23M

Select item 952568312.

Structural analysis of human CEACAM1 oligomerization

Amit K. Gandhi, Zhen-Yu J. Sun, Yu-Hwa Huang, Walter M. Kim, Chao Yang, Gregory A. Petsko, Nicole Beauchemin, Richard S. Blumberg

Commun Biol. 2022; 5: 1042. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03996-4

PMCID:: PMC9525683

Abstract Article PDF–2.6M

Select item 927995213.

Elevation of neutrophil carcinoembryonic antigen‐related cell adhesion molecule 1 associated with multiple inflammatory mediators was related to different clinical stages in ischemic stroke patients

Yi Zhang, Yijie Wang, Wei Wu, Ping Liu, Shanshan Sun, Meng Hong, Yuan Yuan, Qi Xia, Zhi Chen

J Clin Lab Anal. 2022 Jul; 36(7): e24526. Published online 2022 Jun 3. doi: 10.1002/jcla.24526

PMCID:: PMC9279952

Abstract Article PDF–3.7M

Select item 908124214.

Human CEACAM1 N-domain Dimerization is Independent from Glycan Modifications

Meagan Belcher Dufrisne, Nicole Swope, Marissa Kieber, Jeong-Yeh Yang, Ji Han, Jason Li, Kelley W. Moremen, James H. Prestegard, Linda Columbus

Structure. Author manuscript; available in PMC 2023 May 5.

Published in final edited form as: Structure. 2022 May 5; 30(5): 658–670.e5. Published online 2022 Feb 25. doi: 10.1016/j.str.2022.02.003

PMCID:: PMC9081242

Abstract Article PDF–2.3M

Select item 899448915.

The adapter SASH1 acts through NOTCH1 and its inhibitor DLK1 in a 3D model of lumenogenesis involving CEACAM1

Kandis Stubblefield, Jennifer Chean, Tung Nguyen, Charng-jui Chen, John E. Shively

Exp Cell Res. Author manuscript; available in PMC 2022 Apr 9.

Published in final edited form as: Exp Cell Res. 2017 Oct 15; 359(2): 384–393. Published online 2017 Aug 18. doi: 10.1016/j.yexcr.2017.08.022

PMCID:: PMC8994489

Abstract Article PDF–3.2M

Select item 882080616.

T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction

Jessica Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf-Dietrich Doecke, Florian Wessel, Yingzi Ge, Eva Maria Gutierrez, Rafael Carretero, Christoph Freiberg, Uwe Gritzan, Merlin Luetke-Eversloh, Sven Golfier, Oliver Von Ahsen, Valentina Volpin, Antonio Sorrentino, Anchana Rathinasamy, Maria Xydia, Robert Lohmayer, Julian Sax, Ayse Nur-Menevse, Abir Hussein, Slava Stamova, Georg Beckmann, Julian Marius Glueck, Dorian Schoenfeld, Joerg Weiske, Dieter Zopf, Rienk Offringa, Bertolt Kreft, Philipp Beckhove, Joerg Willuda

Oncoimmunology. 2022; 11(1): 2008110. Published online 2021 Dec 30. doi: 10.1080/2162402X.2021.2008110