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Items: 1 to 20 of 27

1.
USP11 deubiquitinates E-cadherin and maintains the luminal fate of mammary tumor cells to suppress breast cancer
Tao Qian, Feng Bai, Shiwen Zhang, Yuping Xu, Yuchan Wang, Shuping Yuan, Xiong Liu, Yaru Du, Bin Peng, Wei-Guo Zhu, Xingzhi Xu, Xin-Hai Pei
J Biol Chem. 2024 Oct; 300(10): 107768. Published online 2024 Sep 11. doi: 10.1016/j.jbc.2024.107768
PMCID:
PMC11497446
AbstractArticlePDF–3.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II
Jia-yun Ni, Xin Wang, Hong-yan Xie, Ning-hao Yang, Jing-yao Li, Xi-ang Sun, Heng-jiang Guo, Li Zhou, Wei Zhang, Jun Liu, Li-min Lu
Acta Pharmacol Sin. 2023 Mar; 44(3): 584–595. Published online 2022 Aug 31. doi: 10.1038/s41401-022-00977-5
PMCID:
PMC9958121
AbstractArticlePDF–5.5M
4.
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia
Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437
PMCID:
PMC9733937
AbstractArticlePDF–2.2M
5.
X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women
Yan Yan, Xinming Wang, Dale Chaput, Min-Kyoo Shin, Yeojung Koh, Li Gan, Andrew A. Pieper, Jung-A A. Woo, David E. Kang
Cell. Author manuscript; available in PMC 2023 Oct 13.
Published in final edited form as: Cell. 2022 Oct 13; 185(21): 3913–3930.e19. Published online 2022 Oct 4. doi: 10.1016/j.cell.2022.09.002
PMCID:
PMC9588697
AbstractArticlePDF–1.8M
6.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
7.
USP11 regulates autophagy-dependent ferroptosis after spinal cord ischemia-reperfusion injury by deubiquitinating Beclin 1
Yuluo Rong, Jin Fan, Chengyue Ji, Zhuanghui Wang, Xuhui Ge, Jiaxing Wang, Wu Ye, Guoyong Yin, Weihua Cai, Wei Liu
Cell Death Differ. 2022 Jun; 29(6): 1164–1175. Published online 2021 Nov 27. doi: 10.1038/s41418-021-00907-8
PMCID:
PMC9177661
AbstractArticlePDF–7.6M
8.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
9.
Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization
Shang-Yin Chiang, Hsin-Chieh Wu, Shu-Yu Lin, Hsin-Yi Chen, Chia-Fang Wang, Nai-Hsing Yeh, Jou-Ho Shih, Yi-Shuian Huang, Hung-Chih Kuo, Shen-Ju Chou, Ruey-Hwa Chen
Sci Adv. 2021 Feb; 7(7): eabc6093. Published online 2021 Feb 12. doi: 10.1126/sciadv.abc6093
PMCID:
PMC7880594
AbstractArticlePDF–6.1M
10.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
11.
PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression
Mi Kyung Park, Yixin Yao, Weiya Xia, Stephanie Rebecca Setijono, Jae Hwan Kim, Isabelle K. Vila, Hui-Hsuan Chiu, Yun Wu, Enrique González Billalabeitia, Min Gyu Lee, Robert G. Kalb, Mien-Chie Hung, Pier Paolo Pandolfi, Su Jung Song, Min Sup Song
Nat Commun. 2019; 10: 636. Published online 2019 Feb 7. doi: 10.1038/s41467-019-08481-x
PMCID:
PMC6367354
AbstractArticlePDF–7.4M
12.
De-ubiquitinating enzyme, USP11, promotes transforming growth factor β-1 signaling through stabilization of transforming growth factor β receptor II
A M Jacko, L Nan, S Li, J Tan, J Zhao, D J Kass, Y Zhao
Cell Death Dis. 2016 Nov; 7(11): e2474. Published online 2016 Nov 17. doi: 10.1038/cddis.2016.371
PMCID:
PMC5260874
AbstractArticlePDF–2.3M
13.
Destabilization of Lysophosphatidic Acid Receptor 1 Reduces Cytokine Release and Protects Against Lung Injury
Jing Zhao, Jianxin Wei, Su Dong, Rachel K. Bowser, Lina Zhang, Anastasia M. Jacko, Yutong Zhao
EBioMedicine. 2016 Aug; 10: 195–203. Published online 2016 Jul 18. doi: 10.1016/j.ebiom.2016.07.020
PMCID:
PMC5006730
AbstractArticlePDF–1.5M
14.
Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11
Caitlyn Vlasschaert, Xuhua Xia, Josée Coulombe, Douglas A. Gray
BMC Evol Biol. 2015; 15: 230. Published online 2015 Oct 26. doi: 10.1186/s12862-015-0511-1
PMCID:
PMC4624187
AbstractArticlePDF–3.0M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
USP11 augments TGFβ signalling by deubiquitylating ALK5
Mazin A. Al-Salihi, Lina Herhaus, Thomas Macartney, Gopal P. Sapkota
Open Biol. 2012 Jun; 2(6): 120063. doi: 10.1098/rsob.120063
PMCID:
PMC3390794
AbstractArticlePDF–1.9M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor
Goedele N Maertens, Selma El Messaoudi-Aubert, Sarah Elderkin, Kevin Hiom, Gordon Peters
EMBO J. 2010 Aug 4; 29(15): 2553–2565. Published online 2010 Jul 2. doi: 10.1038/emboj.2010.129
PMCID:
PMC2928679
AbstractArticlePDF–1.0M
20.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K

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