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Items: 1 to 20 of 23

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy
Tatyana M. Khomenko, Alexandra L. Zakharenko, Arina A. Chepanova, Ekaterina S. Ilina, Olga D. Zakharova, Vasily I. Kaledin, Valeriy P. Nikolin, Nelly A. Popova, Dina V. Korchagina, Jóhannes Reynisson, Raina Chand, Daniel M. Ayine-Tora, Jinal Patel, Ivanhoe K. H. Leung, Konstantin P. Volcho, Nariman F. Salakhutdinov, Olga I. Lavrik
Int J Mol Sci. 2020 Jan; 21(1): 126. Published online 2019 Dec 23. doi: 10.3390/ijms21010126
PMCID:
PMC6982354
AbstractArticlePDF–2.7M
3.
Reactive oxygen species stress increases accumulation of tyrosyl-DNA phsosphodiesterase 1 within mitochondria
Hok Khim Fam, Kunho Choi, Lauren Fougner, Chinten James Lim, Cornelius F. Boerkoel
Sci Rep. 2018; 8: 4304. Published online 2018 Mar 9. doi: 10.1038/s41598-018-22547-8
PMCID:
PMC5844879
AbstractArticlePDF–6.1M
4.
Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage
Shih-Chieh Chiang, Martin Meagher, Nick Kassouf, Majid Hafezparast, Peter J. McKinnon, Rachel Haywood, Sherif F. El-Khamisy
Sci Adv. 2017 Apr; 3(4): e1602506. Published online 2017 Apr 28. doi: 10.1126/sciadv.1602506
PMCID:
PMC5409496
AbstractArticlePDF–943K
5.
Aberrant Topoisomerase-1-DNA Lesions are Pathogenic in Neurodegenerative Genome Instability Syndromes
Sachin Katyal, Youngsoo Lee, Karin C. Nitiss, Susanna M. Downing, Yang Li, Mikio Shimada, Jingfeng Zhao, Helen R. Russell, John H. J. Petrini, John L. Nitiss, Peter J. McKinnon
Nat Neurosci. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Nat Neurosci. 2014 Jun; 17(6): 813–821. Published online 2014 May 4. doi: 10.1038/nn.3715
PMCID:
PMC4074009
AbstractArticlePDF–2.2M
6.
R-Loops in Proliferating Cells but Not in the Brain: Implications for AOA2 and Other Autosomal Recessive Ataxias
Abrey J. Yeo, Olivier J. Becherel, John E. Luff, Jason K. Cullen, Thidathip Wongsurawat, Piroon Jenjaroenpoon, Vladimir A. Kuznetsov, Peter J. McKinnon, Martin F. Lavin
PLoS One. 2014; 9(3): e90219. Published online 2014 Mar 17. doi: 10.1371/journal.pone.0090219
Correction in:
PLoS One. 2014; 9(8): e105258.
PMCID:
PMC3956458
AbstractArticlePDF–7.7M
7.
Pol β associated complex and base excision repair factors in mouse fibroblasts
Rajendra Prasad, Jason G. Williams, Esther W. Hou, Samuel H. Wilson
Nucleic Acids Res. 2012 Dec; 40(22): 11571–11582. Published online 2012 Oct 5. doi: 10.1093/nar/gks898
PMCID:
PMC3526277
AbstractArticlePDF–2.3M
8.
TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1
Zhihong Zeng, Abhishek Sharma, Limei Ju, Junko Murai, Lieve Umans, Liesbeth Vermeire, Yves Pommier, Shunichi Takeda, Danny Huylebroeck, Keith W. Caldecott, Sherif F. El-Khamisy
Nucleic Acids Res. 2012 Sep; 40(17): 8371–8380. Published online 2012 Jun 26. doi: 10.1093/nar/gks622
PMCID:
PMC3458563
AbstractArticlePDF–627K
9.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
10.
DNA Ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair
Yankun Gao, Sachin Katyal, Youngsoo Lee, Jingfeng Zhao, Jerold E. Rehg, Helen R. Russell, Peter J. McKinnon
Nature. Author manuscript; available in PMC 2011 Sep 10.
Published in final edited form as: Nature. 2011 Mar 10; 471(7337): 240–244. doi: 10.1038/nature09773
PMCID:
PMC3079429
AbstractArticlePDF–2.6M
11.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
12.
Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria
Benu Brata Das, Thomas S. Dexheimer, Kasthuraiah Maddali, Yves Pommier
Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46): 19790–19795. Published online 2010 Nov 1. doi: 10.1073/pnas.1009814107
PMCID:
PMC2993338
AbstractArticlePDF–952K
13.
In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation
Amy J. Hawkins, Mark A. Subler, Konstantin Akopiants, Jenny L. Wiley, Shirley M. Taylor, Ann C. Rice, Jolene J. Windle, Kristoffer Valerie, Lawrence F. Povirk
DNA Repair (Amst) Author manuscript; available in PMC 2010 May 1.
Published in final edited form as: DNA Repair (Amst). 2009 May 1; 8(5): 654–663. Published online 2009 Feb 10. doi: 10.1016/j.dnarep.2008.12.012
PMCID:
PMC2844109
AbstractArticlePDF–1.8M
14.
Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin
Sherif F. El-Khamisy, Sachin Katyal, Poorvi Patel, Limei Ju, Peter J. McKinnon, Keith W. Caldecott
DNA Repair (Amst) 2009 Jun 4; 8(6): 760–766. doi: 10.1016/j.dnarep.2009.02.002
PMCID:
PMC2693503
AbstractArticle
15.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
16.
TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo
Sachin Katyal, Sherif F El-Khamisy, Helen R Russell, Yang Li, Limei Ju, Keith W Caldecott, Peter J McKinnon
EMBO J. 2007 Nov 14; 26(22): 4720–4731. Published online 2007 Oct 4. doi: 10.1038/sj.emboj.7601869
PMCID:
PMC2080805
AbstractArticlePDF–589K
17.
Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?
Ryuki Hirano, Heidrun Interthal, Cheng Huang, Tomonori Nakamura, Kimiko Deguchi, Kunho Choi, Meenakshi B Bhattacharjee, Kimiyoshi Arimura, Fujio Umehara, Shuji Izumo, Jennifer L Northrop, Mustafa A M Salih, Ken Inoue, Dawna L Armstrong, James J Champoux, Hiroshi Takashima, Cornelius F Boerkoel
EMBO J. 2007 Nov 14; 26(22): 4732–4743. Published online 2007 Oct 18. doi: 10.1038/sj.emboj.7601885
PMCID:
PMC2080798
AbstractArticlePDF–745K
18.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
19.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
20.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M

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