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Select item 110630511.

Glis2 is an early effector of polycystin signaling and a target for therapy in polycystic kidney disease

Chao Zhang, Michael Rehman, Xin Tian, Steven Lim Cho Pei, Jianlei Gu, Thomas A. Bell, 3rd, Ke Dong, Ming Shen Tham, Yiqiang Cai, Zemeng Wei, Felix Behrens, Anton M. Jetten, Hongyu Zhao, Monkol Lek, Stefan Somlo

Nat Commun. 2024; 15: 3698. Published online 2024 May 1. doi: 10.1038/s41467-024-48025-6

PMCID:: PMC11063051

Abstract Article PDF–4.8M

Select item 109518682.

Long noncoding RNA Glis2 regulates podocyte mitochondrial dysfunction and apoptosis in diabetic nephropathy via sponging miR‐328‐5p

Ting Wang, Yanxia Chen, Zhihong Liu, Jing Zhou, Na Li, Yue Shan, Yinxi He

J Cell Mol Med. 2024 Apr; 28(7): e18204. Published online 2024 Mar 20. doi: 10.1111/jcmm.18204

PMCID:: PMC10951868

Abstract Article PDF–18M

Select item 97925723.

GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation

Haoye Zhang, Pengcheng Zhou, Wu Xing, Limin Chen, Yangmei Zhou, Hui Yang, Kangkang Fu, Zhenguo Liu

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 355–372. Published online 2022 Oct 28. doi: 10.1016/j.jcmgh.2022.10.015

PMCID:: PMC9792572

Abstract Article PDF–6.3M

Select item 91896614.

Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance

Laura Thirouard, Hélène Holota, Mélusine Monrose, Manon Garcia, Angélique de Haze, Christelle Damon‐Soubeyrand, Yoan Renaud, Jean‐Paul Saru, Alessia Perino, Kristina Schoonjans, Claude Beaudoin, David H. Volle

Adv Sci (Weinh) 2022 Jun; 9(17): 2200626. Published online 2022 Apr 18. doi: 10.1002/advs.202200626

PMCID:: PMC9189661

Abstract Article PDF–6.2M

Select item 81264795.

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model

Leticia L. Niborski, Mélanie Paces-Fessy, Pierbruno Ricci, Adeline Bourgeois, Pedro Magalhães, Maria Kuzma-Kuzniarska, Celine Lesaulnier, Martin Reczko, Edwige Declercq, Petra Zürbig, Alain Doucet, Muriel Umbhauer, Silvia Cereghini

Dis Model Mech. 2021 May 1; 14(5): dmm047498. Published online 2021 May 4. doi: 10.1242/dmm.047498

PMCID:: PMC8126479

Abstract Article

Select item 69438026.

Innate Immune Signaling Contributes to Tubular Cell Senescence in the Glis2 Knockout Mouse Model of Nephronophthisis

Heng Jin, Yan Zhang, Dingxiao Liu, Shan Shanshan Wang, Qiong Ding, Prerna Rastogi, Madison Purvis, Angela Wang, Sarah Elhadi, Chongyu Ren, Chao Cao, Yanfen Chai, Peter Igarashi, Anton M. Jetten, Dongmei Lu, Massimo Attanasio

Am J Pathol. 2020 Jan; 190(1): 176–189. doi: 10.1016/j.ajpath.2019.09.013

PMCID:: PMC6943802

Abstract Article PDF–8.8M

Select item 63813887.

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System

Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund

Gastroenterology. 2018 Feb; 154(3): 624–636. doi: 10.1053/j.gastro.2017.10.005

PMCID:: PMC6381388

Abstract Article

Select item 55840748.

Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease

Dongmei Lu, Alysha Rauhauser, Binghua Li, Chongyu Ren, Kayla McEnery, Jili Zhu, Moumita Chaki, Komal Vadnagara, Sarah Elhadi, Anton M. Jetten, Peter Igarashi, Massimo Attanasio

Kidney Int. Author manuscript; available in PMC 2017 Sep 5.

Published in final edited form as: Kidney Int. 2016 Jun; 89(6): 1307–1323. doi: 10.1016/j.kint.2016.03.006

PMCID:: PMC5584074

Abstract Article PDF–1.4M

Select item 48136689.

Functional screen identifies regulators of murine hematopoietic stem cell repopulation

Per Holmfeldt, Miguel Ganuza, Himangi Marathe, Bing He, Trent Hall, Guolian Kang, Joseph Moen, Jennifer Pardieck, Angelica C. Saulsberry, Alba Cico, Ludovic Gaut, Daniel McGoldrick, David Finkelstein, Kai Tan, Shannon McKinney-Freeman

J Exp Med. 2016 Mar 7; 213(3): 433–449. doi: 10.1084/jem.20150806

Correction in:: J Exp Med. 2016 Oct 17; 213(11): 2525.

PMCID:: PMC4813668

Abstract Article PDF–3.0M

Select item 462894810.

Hedgehog signaling indirectly affects tubular cell survival after obstructive kidney injury

Alysha A. Rauhauser, Chongyu Ren, Dongmei Lu, Binghua Li, Jili Zhu, Kayla McEnery, Komal Vadnagara, Diana Zepeda-Orozco, Xin J. Zhou, Fangming Lin, Anton M. Jetten, Massimo Attanasio

Am J Physiol Renal Physiol. 2015 Nov 1; 309(9): F770–F778. Published online 2015 Aug 19. doi: 10.1152/ajprenal.00232.2015

PMCID:: PMC4628948

Abstract Article

Select item 357241011.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 318899212.

Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs

Binghua Li, Alysha A. Rauhauser, Julie Dai, Ramanavelan Sakthivel, Peter Igarashi, Anton M. Jetten, Massimo Attanasio

Hum Mol Genet. 2011 Nov 1; 20(21): 4155–4166. Published online 2011 Aug 4. doi: 10.1093/hmg/ddr339

PMCID:: PMC3188992

Abstract Article PDF–463K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311015114.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

Select item 303932415.

Identification of Nuclear Localization, DNA Binding, and Transactivating Mechanisms of Krüppel-like Zinc Finger Protein Gli-Similar 2 (Glis2)

Shivakumar Vasanth, Gary ZeRuth, Hong Soon Kang, Anton M. Jetten

J Biol Chem. 2011 Feb 11; 286(6): 4749–4759. Published online 2010 Dec 2. doi: 10.1074/jbc.M110.165951

PMCID:: PMC3039324

Abstract Article PDF–3.6M

Select item 255627016.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 226841117.

Krüppel-Like Zinc Finger Protein Glis2 Is Essential for the Maintenance of Normal Renal Functions

Yong-Sik Kim, Hong Soon Kang, Ronald Herbert, Ju Youn Beak, Jennifer B. Collins, Sherry F. Grissom, Anton M. Jetten

Mol Cell Biol. 2008 Apr; 28(7): 2358–2367. Published online 2008 Jan 28. doi: 10.1128/MCB.01722-07

PMCID:: PMC2268411

Abstract Article PDF–848K

Select item 185503718.

The Transcriptional Repressor Glis2 Is a Novel Binding Partner for p120 Catenin

Catherine Rose Hosking, Fausto Ulloa, Catherine Hogan, Emma C. Ferber, Angélica Figueroa, Kris Gevaert, Walter Birchmeier, James Briscoe, Yasuyuki Fujita

Mol Biol Cell. 2007 May; 18(5): 1918–1927. doi: 10.1091/mbc.E06-10-0941

PMCID:: PMC1855037

Abstract Article PDF–1.8M

Select item 130159519.

Krüppel-like zinc finger protein Gli-similar 2 (Glis2) represses transcription through interaction with C-terminal binding protein 1 (CtBP1)

Seong-Chul Kim, Yong-Sik Kim, Anton M. Jetten

Nucleic Acids Res. 2005; 33(21): 6805–6815. Published online 2005 Dec 2. doi: 10.1093/nar/gki985

PMCID:: PMC1301595

Abstract Article PDF–557K

Select item 43978320.

Genomic Analysis of Mouse Retinal Development

Seth Blackshaw, Sanjiv Harpavat, Jeff Trimarchi, Li Cai, Haiyan Huang, Winston P Kuo, Griffin Weber, Kyungjoon Lee, Rebecca E Fraioli, Seo-Hee Cho, Rachel Yung, Elizabeth Asch, Lucila Ohno-Machado, Wing H Wong, Constance L Cepko

PLoS Biol. 2004 Sep; 2(9): e247. Published online 2004 Jun 29. doi: 10.1371/journal.pbio.0020247

PMCID:: PMC439783

Abstract Article PDF–975K

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