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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 83553012.

NEK1-mediated retromer trafficking promotes blood–brain barrier integrity by regulating glucose metabolism and RIPK1 activation

Huibing Wang, Weiwei Qi, Chengyu Zou, Zhangdan Xie, Mengmeng Zhang, Masanori Gomi Naito, Lauren Mifflin, Zhen Liu, Ayaz Najafov, Heling Pan, Bing Shan, Ying Li, Zheng-Jiang Zhu, Junying Yuan

Nat Commun. 2021; 12: 4826. Published online 2021 Aug 10. doi: 10.1038/s41467-021-25157-7

PMCID:: PMC8355301

Abstract Article PDF–9.4M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 60421064.

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis

Palak Amin, Marcus Florez, Ayaz Najafov, Heling Pan, Jiefei Geng, Dimitry Ofengeim, Slawomir A. Dziedzic, Huibing Wang, Vica Jean Barrett, Yasushi Ito, Matthew J. LaVoie, Junying Yuan

Proc Natl Acad Sci U S A. 2018 Jun 26; 115(26): E5944–E5953. Published online 2018 Jun 11. doi: 10.1073/pnas.1806973115

PMCID:: PMC6042106

Abstract Article PDF–2.0M

Select item 56288685.

Miguel A. Brieño-Enríquez, Stefannie L. Moak, J. Kim Holloway, Paula E. Cohen

PLoS One. 2017; 12(10): e0185780. Published online 2017 Oct 5. doi: 10.1371/journal.pone.0185780

PMCID:: PMC5628868

Abstract Article PDF–3.0M

Select item 53256146.

Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members

Tim Sonntag, James J. Moresco, Joan M. Vaughan, Shigenobu Matsumura, John R. Yates, III, Marc Montminy

PLoS One. 2017; 12(2): e0173013. Published online 2017 Feb 24. doi: 10.1371/journal.pone.0173013

PMCID:: PMC5325614

Abstract Article PDF–3.2M

Select item 51237707.

Cohesin removal along the chromosome arms during the first meiotic division depends on a NEK1-PP1γ-WAPL axis in the mouse

Miguel A. Brieño-Enríquez, Stefannie L. Moak, Melissa Toledo, Joshua J. Filter, Stephen Gray, José L. Barbero, Paula E. Cohen, J. Kim Holloway

Cell Rep. Author manuscript; available in PMC 2016 Nov 25.

Published in final edited form as: Cell Rep. 2016 Oct 18; 17(4): 977–986. doi: 10.1016/j.celrep.2016.09.059

PMCID:: PMC5123770

Abstract Article PDF–1.4M

Select item 44221898.

Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease

Yumay Chen, Huai-Chin Chiang, Patricia Litchfield, Michelle Pena, Charity Juang, Daniel J Riley

J Biomed Sci. 2014; 21(1): 63. Published online 2014 Jul 17. doi: 10.1186/s12929-014-0063-5

PMCID:: PMC4422189

Abstract Article PDF–4.9M

Select item 38272829.

MicroRNA-20a Constrains p300-Driven Myocardial Angiogenic Transcription by Direct Targeting of p300

Lina A. Shehadeh, Salil Sharma, Mônica Pessanha, Jian Qin Wei, Jing Liu, Huijun Yuan, Claudia O. Rodrigues, Michaela Scherr, Nicholas F. Tsinoremas, Nanette H. Bishopric

PLoS One. 2013; 8(11): e79133. Published online 2013 Nov 13. doi: 10.1371/journal.pone.0079133

PMCID:: PMC3827282

Abstract Article PDF–4.8M

Select item 326989610.

Nek1 and TAZ Interact to Maintain Normal Levels of Polycystin 2

Hyungshin Yim, Chang K. Sung, John You, Yu Tian, Thomas Benjamin

J Am Soc Nephrol. 2011 May; 22(5): 832–837. doi: 10.1681/ASN.2010090992

PMCID:: PMC3269896

Abstract Article

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317399512.

Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR

Yumay Chen, Chi-Fen Chen, Daniel J Riley, Phang-Lang Chen

Cell Cycle. 2011 Feb 15; 10(4): 655–663. Published online 2011 Feb 15. doi: 10.4161/cc.10.4.14814

PMCID:: PMC3173995

Abstract Article PDF–519K

Select item 302597513.

Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability

Yumay Chen, Chi-Fen Chen, Huai-Chin Chiang, Michelle Pena, Rosaria Polci, Randy L Wei, Robert A Edwards, Donna E Hansel, Phang-Lang Chen, Daniel J Riley

Mol Cancer. 2011; 10: 5. Published online 2011 Jan 10. doi: 10.1186/1476-4598-10-5

PMCID:: PMC3025975

Abstract Article PDF–3.3M

Select item 302253414.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 259719115.

Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control

Yumay Chen, Phang-Lang Chen, Chi-Fen Chen, Xianzhi Jiang, Daniel J. Riley

Cell Cycle. Author manuscript; available in PMC 2008 Dec 8.

Published in final edited form as: Cell Cycle. 2008 Oct; 7(20): 3194–3201. Published online 2008 Oct 18. doi: 10.4161/cc.7.20.6815

PMCID:: PMC2597191

Abstract Article PDF–2.7M

Select item 244259016.

The NIMA-family kinase, Nek1 affects the stability of centrosomes and ciliogenesis

Mark C White, Lynne M Quarmby

BMC Cell Biol. 2008; 9: 29. Published online 2008 Jun 4. doi: 10.1186/1471-2121-9-29

PMCID:: PMC2442590

Abstract Article PDF–1.6M

Select item 55681017.

A mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells.

K Letwin, L Mizzen, B Motro, Y Ben-David, A Bernstein, T Pawson

EMBO J. 1992 Oct; 11(10): 3521–3531. doi: 10.1002/j.1460-2075.1992.tb05435.x

PMCID:: PMC556810

Summary Page Browse PDF–3.6M

Select item 52479518.

Moe R. Mahjoub, M. Qasim Rasi, Lynne M. Quarmby

Mol Biol Cell. 2004 Nov; 15(11): 5172–5186. doi: 10.1091/mbc.E04-07-0571

PMCID:: PMC524795

Abstract Article PDF–706K

Select item 40366419.

Exploration of the Cell-Cycle Genes Found Within the RIKEN FANTOM2 Data Set

Alistair R.R. Forrest, Darrin Taylor, RIKEN GER Group, GSL Members, Sean Grimmond

Genome Res. 2003 Jun; 13(6b): 1366–1375. doi: 10.1101/gr.1012403

PMCID:: PMC403664

Abstract Article PDF–287K

Select item 31099220.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

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