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Select item 105269801.

Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma

Chen Chen, June Ho Shin, Zhuoqing Fang, Kevin Brennan, Nina B. Horowitz, Kathleen L. Pfaff, Emma L. Welsh, Scott J. Rodig, Olivier Gevaert, Or Gozani, Ravindra Uppaluri, John B. Sunwoo

Cancer Res. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Cancer Res. 2023 Aug 15; 83(16): 2645–2655. doi: 10.1158/0008-5472.CAN-22-3114

PMCID:: PMC10526980

Abstract Article PDF–1.6M

Select item 102307552.

NSD1 deposits histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons

Nicole Hamagami, Dennis Y. Wu, Adam W. Clemens, Sabin A. Nettles, Aidan Li, Harrison W. Gabel

Mol Cell. Author manuscript; available in PMC 2024 May 4.

Published in final edited form as: Mol Cell. 2023 May 4; 83(9): 1412–1428.e7. Published online 2023 Apr 24. doi: 10.1016/j.molcel.2023.04.001

PMCID:: PMC10230755

Abstract Article PDF–2.4M

Select item 97507913.

H3K36 methyltransferase NSD1 is essential for normal B1 and B2 cell development and germinal center formation

Sulan Zhai, Min Cao, Han Zhou, Huamin Zhu, Tongchang Xu, Yuliang Wang, Xiaoming Wang, Zhenming Cai

Front Immunol. 2022; 13: 959021. Published online 2022 Nov 30. doi: 10.3389/fimmu.2022.959021

PMCID:: PMC9750791

Abstract Article PDF–3.2M

Select item 95886794.

Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas

Yinglu Li, Elizabeth M. Goldberg, Xiao Chen, Xinjing Xu, John T. McGuire, Giuseppe Leuzzi, Dimitris Karagiannis, Tiffany Tate, Nargess Farhangdoost, Cynthia Horth, Esther Dai, Zhiming Li, Zhiguo Zhang, Benjamin Izar, Jianwen Que, Alberto Ciccia, Jacek Majewski, Angela J. Yoon, Laurie Ailles, Cathy Lee Mendelsohn, Chao Lu

Mol Cell. Author manuscript; available in PMC 2023 Oct 20.

Published in final edited form as: Mol Cell. 2022 Oct 20; 82(20): 3901–3918.e7. Published online 2022 Oct 6. doi: 10.1016/j.molcel.2022.09.007

PMCID:: PMC9588679

Abstract Article PDF–4.5M

Select item 91340115.

Analysis of a miR-148a Targetome in B Cell Central Tolerance

Fengge Ma, Yating Zhan, Rocío Bartolomé-Cabrero, Wei Ying, Masahide Asano, Zhe Huang, Changchun Xiao, Alicia González-Martín

Front Immunol. 2022; 13: 861655. Published online 2022 May 12. doi: 10.3389/fimmu.2022.861655

PMCID:: PMC9134011

Abstract Article PDF–4.4M

Select item 85106136.

A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation

Shusaku Abe, Hiroaki Nagatomo, Hiroyuki Sasaki, Takashi Ishiuchi

Epigenetics. 2021; 16(10): 1123–1134. Published online 2020 Nov 16. doi: 10.1080/15592294.2020.1841873

PMCID:: PMC8510613

Abstract Article PDF–7.2M

Select item 83338717.

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice

Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao

Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931

PMCID:: PMC8333871

Abstract Article PDF–1.4M

Select item 82164578.

The H3K36me2 methyltransferase NSD1 modulates H3K27ac at active enhancers to safeguard gene expression

Yuan Fang, Yin Tang, Yanjun Zhang, Yixin Pan, Junqi Jia, Zhongxing Sun, Weiwu Zeng, Jiaqi Chen, Ying Yuan, Dong Fang

Nucleic Acids Res. 2021 Jun 21; 49(11): 6281–6295. Published online 2021 Jun 9. doi: 10.1093/nar/gkab473

PMCID:: PMC8216457

Abstract Article PDF–3.9M

Select item 79689259.

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam

eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873

PMCID:: PMC7968925

Abstract Article PDF–4.0M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 729331011.

Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia

Katharina Leonards, Marwa Almosailleakh, Samantha Tauchmann, Frederik Otzen Bagger, Cécile Thirant, Sabine Juge, Thomas Bock, Hélène Méreau, Matheus F. Bezerra, Alexandar Tzankov, Robert Ivanek, Régine Losson, Antoine H. F. M. Peters, Thomas Mercher, Juerg Schwaller

Nat Commun. 2020; 11: 2807. Published online 2020 Jun 12. doi: 10.1038/s41467-020-16179-8

PMCID:: PMC7293310

Abstract Article PDF–4.4M

Select item 564508212.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 431955913.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 410492114.

Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis

Jingwen Wu, Jianqiang Bao, Minkyung Kim, Shuiqiao Yuan, Chong Tang, Huili Zheng, Grant S. Mastick, Chen Xu, Wei Yan

Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28): E2851–E2857. Published online 2014 Jun 30. doi: 10.1073/pnas.1407777111

PMCID:: PMC4104921

Abstract Article PDF–1.8M

Select item 408581615.

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse

Julie A. Williams, Naoki Kondo, Takahiro Okabe, Nobuo Takashita, Diane M. Pilchak, Eiki Koyama, Takanaga Ochiai, Deborah Jensen, Motomi Enomoto-Iwamoto, Mon-Li Chu, Norbert Ghyselinck, Pierre Chambon, Maurizio Pacifici, Masahiro Iwamoto

Dev Biol. Author manuscript; available in PMC 2014 Jul 8.

Published in final edited form as: Dev Biol. 2009 Apr 15; 328(2): 315–327. Published online 2009 Feb 3. doi: 10.1016/j.ydbio.2009.01.031

PMCID:: PMC4085816

Abstract Article PDF–3.2M

Select item 407349416.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 383482917.

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors

Chun Ming Chan, Joel Fulton, Cristina Montiel-Duarte, Hilary M. Collins, Neetu Bharti, Frances R. Wadelin, Paula M. Moran, Nigel P. Mongan, David M. Heery

Nucleic Acids Res. 2013 Nov; 41(21): 9663–9679. Published online 2013 Aug 23. doi: 10.1093/nar/gkt761

PMCID:: PMC3834829

Abstract Article PDF–3.7M

Select item 382939818.

Histone H2A Ubiquitination Inhibits the Enzymatic Activity of H3 Lysine 36 Methyltransferases

Gang Yuan, Ben Ma, Wen Yuan, Zhuqiang Zhang, Ping Chen, Xiaojun Ding, Li Feng, Xiaohua Shen, She Chen, Guohong Li, Bing Zhu

J Biol Chem. 2013 Oct 25; 288(43): 30832–30842. Published online 2013 Sep 9. doi: 10.1074/jbc.M113.475996

PMCID:: PMC3829398

Abstract Article PDF–2.6M

Select item 377676519.

NSD1 Mitigates Caspase-1 Activation by Listeriolysin O in Macrophages

Olivia S. Sakhon, Kaitlin A. Victor, Anthony Choy, Tokuji Tsuchiya, Thomas Eulgem, Joao H. F. Pedra

PLoS One. 2013; 8(9): e75911. Published online 2013 Sep 18. doi: 10.1371/journal.pone.0075911

PMCID:: PMC3776765

Abstract Article PDF–2.1M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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