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Select item 107700421.

Nuclear Hsp104 safeguards the dormant translation machinery during quiescence

Verena Kohler, Andreas Kohler, Lisa Larsson Berglund, Xinxin Hao, Sarah Gersing, Axel Imhof, Thomas Nyström, Johanna L. Höög, Martin Ott, Claes Andréasson, Sabrina Büttner

Nat Commun. 2024; 15: 315. Published online 2024 Jan 5. doi: 10.1038/s41467-023-44538-8

PMCID:: PMC10770042

Abstract Article PDF–5.1M

Select item 102977002.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 98363483.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 96309864.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 93744365.

Ubiquitination drives COPI priming and Golgi SNARE localization

Swapneeta S Date, Peng Xu, Nathaniel L Hepowit, Nicholas S Diab, Jordan Best, Boyang Xie, Jiale Du, Eric R Strieter, Lauren P Jackson, Jason A MacGurn, Todd R Graham

eLife. 2022; 11: e80911. Published online 2022 Jul 29. doi: 10.7554/eLife.80911

PMCID:: PMC9374436

Abstract Article PDF–4.3M

Select item 92098116.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 87703227.

Induction and Aggravation of the Endoplasmic-Reticulum Stress by Membrane-Lipid Metabolic Intermediate Phosphatidyl-N-Monomethylethanolamine

Yuki Ishiwata-Kimata, Quynh Giang Le, Yukio Kimata

Front Cell Dev Biol. 2021; 9: 743018. Published online 2022 Jan 6. doi: 10.3389/fcell.2021.743018

PMCID:: PMC8770322

Abstract Article PDF–1.7M

Select item 85489168.

Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels

Michal Eisenberg-Bord, Naama Zung, Javier Collado, Layla Drwesh, Emma J. Fenech, Amir Fadel, Nili Dezorella, Yury S. Bykov, Doron Rapaport, Ruben Fernandez-Busnadiego, Maya Schuldiner

J Cell Biol. 2021 Nov 1; 220(11): e202104100. Published online 2021 Oct 25. doi: 10.1083/jcb.202104100

PMCID:: PMC8548916

Abstract Article PDF–6.5M

Select item 85212999.

Shortening of membrane lipid acyl chains compensates for phosphatidylcholine deficiency in choline‐auxotroph yeast

Xue Bao, Martijn C Koorengevel, Marian J A Groot Koerkamp, Amir Homavar, Amrah Weijn, Stefan Crielaard, Mike F Renne, Joseph H Lorent, Willie JC Geerts, Michal A Surma, Muriel Mari, Frank C P Holstege, Christian Klose, Anton I P M de Kroon

EMBO J. 2021 Oct 18; 40(20): e107966. Published online 2021 Sep 14. doi: 10.15252/embj.2021107966

PMCID:: PMC8521299

Abstract Article PDF–4.1M

Select item 835352610.

The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription

David Z. Kochan, Julia S. P. Mawer, Jennifer Massen, Kiril Tishinov, Swati Parekh, Martin Graef, Anne Spang, Peter Tessarz

J Cell Sci. 2021 Aug 1; 134(15): jcs259051. Published online 2021 Aug 5. doi: 10.1242/jcs.259051

PMCID:: PMC8353526

Abstract Article

Select item 826033111.

Water soluble lipid precursor contaminants in yeast culture medium ingredients

Mike F Renne, Xue Bao, Anton I P M de Kroon

FEMS Yeast Res. 2020 Aug; 20(5): foaa029. Published online 2020 Jun 27. doi: 10.1093/femsyr/foaa029

PMCID:: PMC8260331

Abstract Article PDF–956K

Select item 805418912.

Choline restores respiration in Psd1-deficient yeast by replenishing mitochondrial phosphatidylethanolamine

Donna M. Iadarola, Alaumy Joshi, Cameron B. Caldwell, Vishal M. Gohil

J Biol Chem. 2021 Jan-Jun; 296: 100539. Published online 2021 Mar 12. doi: 10.1016/j.jbc.2021.100539

PMCID:: PMC8054189

Abstract Article PDF–901K

Select item 794911613.

Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling

Akinori Eiyama, Mari J. Aaltonen, Hendrik Nolte, Takashi Tatsuta, Thomas Langer

J Biol Chem. 2021 Jan-Jun; 296: 100335. Published online 2021 Jan 23. doi: 10.1016/j.jbc.2021.100335

PMCID:: PMC7949116

Abstract Article PDF–1.8M

Select item 794775514.

Suboptimal Global Transcriptional Response Increases the Harmful Effects of Loss-of-Function Mutations

Károly Kovács, Zoltán Farkas, Djordje Bajić, Dorottya Kalapis, Andreea Daraba, Karola Almási, Bálint Kintses, Zoltán Bódi, Richard A Notebaart, Juan F Poyatos, Patrick Kemmeren, Frank C P Holstege, Csaba Pál, Balázs Papp

Mol Biol Evol. 2021 Mar; 38(3): 1137–1150. Published online 2020 Nov 3. doi: 10.1093/molbev/msaa280

PMCID:: PMC7947755

Abstract Article PDF–727K

Select item 772147515.

A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits

Florian Wilfling, Chia-Wei Lee, Philipp S. Erdmann, Yumei Zheng, Dawafuti Sherpa, Stefan Jentsch, Boris Pfander, Brenda A. Schulman, Wolfgang Baumeister

Mol Cell. 2020 Dec 3; 80(5): 764–778.e7. doi: 10.1016/j.molcel.2020.10.030

PMCID:: PMC7721475

Abstract Article

Select item 771875116.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 736825017.

An essential role for cardiolipin in the stability and function of the mitochondrial calcium uniporter

Sagnika Ghosh, Writoban Basu Ball, Travis R. Madaris, Subramanya Srikantan, Muniswamy Madesh, Vamsi K. Mootha, Vishal M. Gohil

Proc Natl Acad Sci U S A. 2020 Jul 14; 117(28): 16383–16390. Published online 2020 Jun 29. doi: 10.1073/pnas.2000640117

PMCID:: PMC7368250

Abstract Article PDF–1.1M

Select item 733750818.

Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress

Nurulain Ho, Wei Sheng Yap, Jiaming Xu, Haoxi Wu, Jhee Hong Koh, Wilson Wen Bin Goh, Bhawana George, Shu Chen Chong, Stefan Taubert, Guillaume Thibault

J Cell Biol. 2020 Jul 6; 219(7): e201909165. Published online 2020 Apr 29. doi: 10.1083/jcb.201909165