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Items: 1 to 20 of 114

1.
Substrate recognition mechanism of the endoplasmic reticulum-associated ubiquitin ligase Doa10
Kevin Wu, Samuel Itskanov, Diane L. Lynch, Yuanyuan Chen, Aasha Turner, James C. Gumbart, Eunyong Park
Nat Commun. 2024; 15: 2182. Published online 2024 Mar 11. doi: 10.1038/s41467-024-46409-2
PMCID:
PMC10928120
AbstractArticlePDF–5.2M
2.
Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle
Michael J. O’Brien, Athar Ansari
Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.
Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968
PMCID:
PMC10872477
AbstractArticlePDF–1.7M
3.
Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE
J. Josephine Botsch, Roswitha Junker, Michèle Sorgenfrei, Patricia P. Ogger, Luca Stier, Susanne von Gronau, Peter J. Murray, Markus A. Seeger, Brenda A. Schulman, Bastian Bräuning
Nat Commun. 2024; 15: 410. Published online 2024 Jan 9. doi: 10.1038/s41467-023-44670-5
PMCID:
PMC10776854
AbstractArticlePDF–6.1M
4.
The social and structural architecture of the yeast protein interactome
André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann
Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5
PMCID:
PMC10700138
AbstractArticlePDF–20M
5.
Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability
Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai
Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108
PMCID:
PMC10551700
AbstractArticlePDF–3.7M
6.
The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions
Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman
Mol Cell. Author manuscript; available in PMC 2024 Jun 15.
Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021
PMCID:
PMC10297700
AbstractArticlePDF–2.0M
7.
Yeast derlin Dfm1 employs a chaperone-like function to resolve misfolded membrane protein stress
Rachel Kandel, Jasmine Jung, Della Syau, Tiffany Kuo, Livia Songster, Casey Horn, Claire Chapman, Analine Aguayo, Sascha Duttke, Christopher Benner, Sonya E. Neal
PLoS Biol. 2023 Jan; 21(1): e3001950. Published online 2023 Jan 23. doi: 10.1371/journal.pbio.3001950
PMCID:
PMC9894555
AbstractArticlePDF–3.3M
8.
Lipid saturation induces degradation of squalene epoxidase for sterol homeostasis and cell survival
Leng-Jie Huang, Rey-Huei Chen
Life Sci Alliance. 2023 Jan; 6(1): e202201612. Published online 2022 Nov 11. doi: 10.26508/lsa.202201612
PMCID:
PMC9652772
AbstractArticlePDF–3.9M
9.
A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans
Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor
Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136
PMCID:
PMC9630986
AbstractArticlePDF–2.2M
10.
Elements of the ERAD ubiquitin ligase Doa10 regulating sequential poly-ubiquitylation of its targets
Adrian B. Mehrtash, Mark Hochstrasser
iScience. 2022 Nov 18; 25(11): 105351. Published online 2022 Oct 13. doi: 10.1016/j.isci.2022.105351
PMCID:
PMC9619350
AbstractArticlePDF–4.1M
11.
Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton
Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019
PMCID:
PMC9286023
AbstractArticle
12.
New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry
Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224
PMCID:
PMC9209811
AbstractArticlePDF–818K
13.
GET pathway mediates transfer of mislocalized tail-anchored proteins from mitochondria to the ER
Shunsuke Matsumoto, Suzuka Ono, Saori Shinoda, Chika Kakuta, Satoshi Okada, Takashi Ito, Tomoyuki Numata, Toshiya Endo
J Cell Biol. 2022 Jun 6; 221(6): e202104076. Published online 2022 Apr 20. doi: 10.1083/jcb.202104076
PMCID:
PMC9026240
AbstractArticlePDF–6.9M
14.
Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast
Laurence Decourty, Christophe Malabat, Emmanuel Frachon, Alain Jacquier, Cosmin Saveanu
Nucleic Acids Res. 2021 Sep 7; 49(15): 8535–8555. Published online 2021 Aug 6. doi: 10.1093/nar/gkab680
PMCID:
PMC8421204
AbstractArticlePDF–2.9M
15.
Protein quality control degron-containing substrates are differentially targeted in the cytoplasm and nucleus by ubiquitin ligases
Christopher M Hickey, Carolyn Breckel, Mengwen Zhang, William C Theune, Mark Hochstrasser
Genetics. 2021 Jan; 217(1): 1–19. Published online 2020 Dec 22. doi: 10.1093/genetics/iyaa031
PMCID:
PMC8045714
AbstractArticlePDF–2.3M
16.
A nuclear-based quality control pathway for non-imported mitochondrial proteins
Viplendra PS Shakya, William A Barbeau, Tianyao Xiao, Christina S Knutson, Max H Schuler, Adam L Hughes
eLife. 2021; 10: e61230. Published online 2021 Mar 18. doi: 10.7554/eLife.61230
PMCID:
PMC7993989
AbstractArticlePDF–2.9M
17.
Loss of protein quality control gene UBR1 sensitizes Saccharomyces cerevisiae to the aminoglycoside hygromycin B
Avery M. Runnebohm, Melissa D. Evans, Adam E. Richardson, Samantha M. Turk, James B. Olesen, Philip J. Smaldino, Eric M. Rubenstein
Fine Focus. Author manuscript; available in PMC 2021 Feb 4.
Published in final edited form as: Fine Focus. 2020 Oct 26; 6(1): 76–83. doi: 10.33043/FF.6.1.76-83
PMCID:
PMC7861132
AbstractArticlePDF–102K
18.
Cross-compartment signal propagation in the mitotic exit network
Xiaoxue Zhou, Wenxue Li, Yansheng Liu, Angelika Amon
eLife. 2021; 10: e63645. Published online 2021 Jan 22. doi: 10.7554/eLife.63645
PMCID:
PMC7822594
AbstractArticlePDF–4.3M
19.
A Systematic Protein Turnover Map for Decoding Protein Degradation
Romain Christiano, Henning Arlt, Sonja Kabatnik, Niklas Mejhert, Zon Weng Lai, Robert V. Farese, Jr., Tobias C. Walther
Cell Rep. Author manuscript; available in PMC 2020 Dec 17.
Published in final edited form as: Cell Rep. 2020 Nov 10; 33(6): 108378. doi: 10.1016/j.celrep.2020.108378
PMCID:
PMC7745259
AbstractArticlePDF–1.1M
20.
Characterization of constitutive ER-phagy of excess membrane proteins
Zhanna Lipatova, Valeriya Gyurkovska, Sarah F. Zhao, Nava Segev
PLoS Genet. 2020 Dec; 16(12): e1009255. Published online 2020 Dec 4. doi: 10.1371/journal.pgen.1009255
PMCID:
PMC7744050
AbstractArticlePDF–4.0M

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