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Select item 110241851.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105115614.

Synergism between CMG helicase and leading strand DNA polymerase at replication fork

Zhichun Xu, Jianrong Feng, Daqi Yu, Yunjing Huo, Xiaohui Ma, Wai Hei Lam, Zheng Liu, Xiang David Li, Toyotaka Ishibashi, Shangyu Dang, Yuanliang Zhai

Nat Commun. 2023; 14: 5849. Published online 2023 Sep 20. doi: 10.1038/s41467-023-41506-0

PMCID:: PMC10511561

Abstract Article PDF–5.3M

Select item 102977005.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102350866.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 92098117.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 91331128.

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer

Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E. Ivanova, Kathryn M. Stevens, Alex Montoya, S. Sunidhi, Nicolas Lopez Carranza, Marcin J. Skwark, Christian Speck

Nat Commun. 2022; 13: 2915. Published online 2022 May 25. doi: 10.1038/s41467-022-30576-1

PMCID:: PMC9133112

Abstract Article PDF–7.2M

Select item 89271179.

Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase

Jiaxuan Cheng, Ningning Li, Yunjing Huo, Shangyu Dang, Bik-Kwoon Tye, Ning Gao, Yuanliang Zhai

Nat Commun. 2022; 13: 1396. Published online 2022 Mar 16. doi: 10.1038/s41467-022-29070-5

Correction in:: Nat Commun. 2022; 13: 2411.

PMCID:: PMC8927117

Abstract Article PDF–6.6M

Select item 877013110.

Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase

Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley, Alessandro Costa

Nat Struct Mol Biol. 2022; 29(1): 10–20. Published online 2021 Dec 28. doi: 10.1038/s41594-021-00698-z

PMCID:: PMC8770131

Abstract Article PDF–12M

Select item 869538211.

A conserved mechanism for regulating replisome disassembly in eukaryotes

Michael Jenkyn-Bedford, Morgan L. Jones, Yasemin Baris, Karim P. M. Labib, Giuseppe Cannone, Joseph T. P. Yeeles, Tom D. Deegan

Nature. 2021; 600(7890): 743–747. Published online 2021 Oct 26. doi: 10.1038/s41586-021-04145-3

PMCID:: PMC8695382

Abstract Article PDF–80M

Select item 857106312.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 844326913.

Chromosomal Mcm2-7 distribution and the genome replication program in species from yeast to humans

Eric J. Foss, Smitha Sripathy, Tonibelle Gatbonton-Schwager, Hyunchang Kwak, Adam H. Thiesen, Uyen Lao, Antonio Bedalov

PLoS Genet. 2021 Sep; 17(9): e1009714. Published online 2021 Sep 2. doi: 10.1371/journal.pgen.1009714

PMCID:: PMC8443269

Abstract Article PDF–3.2M

Select item 804568714.

Interaction of replication factor Sld3 and histone acetyl transferase Esa1 alleviates gene silencing and promotes the activation of late and dormant replication origins

Seiji Tanaka

Genetics. 2021 Jan; 217(1): iyaa001. Published online 2020 Nov 11. doi: 10.1093/genetics/iyaa001

PMCID:: PMC8045687

Abstract Article PDF–873K

Select item 797972615.

Stabilisation of half MCM ring by Cdt1 during DNA insertion

Marina Guerrero-Puigdevall, Narcis Fernandez-Fuentes, Jordi Frigola

Nat Commun. 2021; 12: 1746. Published online 2021 Mar 19. doi: 10.1038/s41467-021-21932-8

PMCID:: PMC7979726

Abstract Article PDF–1.8M

Select item 795452616.

DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

Lorraine De Jesús-Kim, Larry J Friedman, Marko Lõoke, Christian K Ramsoomair, Jeff Gelles, Stephen P Bell

eLife. 2021; 10: e65471. Published online 2021 Feb 22. doi: 10.7554/eLife.65471

PMCID:: PMC7954526

Abstract Article PDF–3.6M

Select item 794844817.

14-3-3 Protein Bmh1 triggers short-range compaction of mitotic chromosomes by recruiting sirtuin deacetylase Hst2

Neha Jain, Petra Janning, Heinz Neumann

J Biol Chem. 2021 Jan-Jun; 296: 100078. Published online 2020 Nov 23. doi: 10.1074/jbc.AC120.014758

PMCID:: PMC7948448

Abstract Article PDF–1.3M

Select item 746261118.

CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold

Tom D Deegan, Progya P Mukherjee, Ryo Fujisawa, Cristian Polo Rivera, Karim Labib

eLife. 2020; 9: e60371. Published online 2020 Aug 17. doi: 10.7554/eLife.60371

PMCID:: PMC7462611

Abstract Article PDF–4.9M

Select item 739869819.

Antagonistic control of DDK binding to licensed replication origins by Mcm2 and Rad53

Syafiq Abd Wahab, Dirk Remus

eLife. 2020; 9: e58571. Published online 2020 Jul 23. doi: 10.7554/eLife.58571

PMCID:: PMC7398698

Abstract Article PDF–2.5M

Select item 739546020.

Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6

Zuanning Yuan, Sarah Schneider, Thomas Dodd, Alberto Riera, Lin Bai, Chunli Yan, Indiana Magdalou, Ivaylo Ivanov, Bruce Stillman, Huilin Li, Christian Speck

Proc Natl Acad Sci U S A. 2020 Jul 28; 117(30): 17747–17756. Published online 2020 Jul 15. doi: 10.1073/pnas.2006231117