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Items: 1 to 20 of 40

1.
Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases
Sherona R. Sirkisoon, Grace L. Wong, Noah R. Aguayo, Daniel L. Doheny, Dongqin Zhu, Angelina T. Regua, Austin Arrigo, Sara G. Manore, Calvin Wagner, Alexandra Thomas, Ravi Singh, Fei Xing, Guangxu Jin, Kounosuke Watabe, Hui-Wen Lo
Cancer Lett. Author manuscript; available in PMC 2023 Aug 1.
Published in final edited form as: Cancer Lett. 2022 Aug 1; 540: 215726. Published online 2022 May 16. doi: 10.1016/j.canlet.2022.215726
PMCID:
PMC9387054
AbstractArticlePDF–1.5M
2.
Ciliary neurotrophic factor is increased in the plasma of patients with obesity and its levels correlate with diabetes and inflammation indices
Jessica Perugini, Eleonora Di Mercurio, Angelica Giuliani, Jacopo Sabbatinelli, Anna Rita Bonfigli, Elena Tortato, Ilenia Severi, Saverio Cinti, Fabiola Olivieri, Carel W. le Roux, Rosaria Gesuita, Antonio Giordano
Sci Rep. 2022; 12: 8331. Published online 2022 May 18. doi: 10.1038/s41598-022-11942-x
PMCID:
PMC9117681
AbstractArticlePDF–2.7M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Ciliary neurotrophic factor: a survival and differentiation inducer in human retinal progenitors
Kamla Dutt, Yang Cao, Ifeoma Ezeonu
In Vitro Cell Dev Biol Anim. Author manuscript; available in PMC 2021 Mar 3.
Published in final edited form as: In Vitro Cell Dev Biol Anim. 2010 Jul; 46(7): 635–646. Published online 2010 Apr 29. doi: 10.1007/s11626-010-9319-x
PMCID:
PMC7927570
AbstractArticlePDF–1.8M
5.
Ciliary neurotrophic factor (CNTF) and its receptor (CNTFRɑ) signal through MAPK/ERK pathway in human prostate tissues: A morphological and biomolecular study
Sonia Fantone, Giovanni Tossetta, Rodolfo Montironi, Martina Senzacqua, Daniela Marzioni, Roberta Mazzucchelli
Eur J Histochem. 2020 Oct 19; 64(4): 3147. Published online 2020 Oct 19. doi: 10.4081/ejh.2020.3147
PMCID:
PMC7586252
AbstractArticlePDF–568K
6.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
7.
Regulation of Rod Phototransduction Machinery by Ciliary Neurotrophic Factor
Rong Wen, Ying Song, Sten Kjellstrom, Atsuhiro Tanikawa, Yun Liu, Yiwen Li, Lian Zhao, Ronald A. Bush, Alan M. Laties, Paul A. Sieving
J Neurosci. 2006 Dec 27; 26(52): 13523–13530. doi: 10.1523/JNEUROSCI.4021-06.2006
PMCID:
PMC6674721
AbstractArticlePDF–504K
8.
CNTF: A Putative Link between Dopamine D2 Receptors and Neurogenesis
Mayra Mori, Julius J. Jefferson, Michele Hummel, David S. Garbe
J Neurosci. 2008 Jun 4; 28(23): 5867–5869. doi: 10.1523/JNEUROSCI.1782-08.2008
PMCID:
PMC6670321
ArticlePDF–102K
9.
Apolipoprotein E Binds to and Potentiates the Biological Activity of Ciliary Neurotrophic Factor
Catherine R. Gutman, Warren J. Strittmatter, Karl H. Weisgraber, William D. Matthew
J Neurosci. 1997 Aug 15; 17(16): 6114–6121. doi: 10.1523/JNEUROSCI.17-16-06114.1997
PMCID:
PMC6568355
AbstractArticlePDF–491K
10.
Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress
Alán Alpár, Péter Zahola, János Hanics, Zsófia Hevesi, Solomiia Korchynska, Marco Benevento, Christian Pifl, Gergely Zachar, Jessica Perugini, Ilenia Severi, Patrick Leitgeb, Joanne Bakker, Andras G Miklosi, Evgenii Tretiakov, Erik Keimpema, Gloria Arque, Ramon O Tasan, Günther Sperk, Katarzyna Malenczyk, Zoltán Máté, Ferenc Erdélyi, Gábor Szabó, Gert Lubec, Miklós Palkovits, Antonio Giordano, Tomas GM Hökfelt, Roman A Romanov, Tamas L Horvath, Tibor Harkany
EMBO J. 2018 Nov 2; 37(21): e100087. Published online 2018 Sep 12. doi: 10.15252/embj.2018100087
PMCID:
PMC6213283
AbstractArticlePDF–3.0M
11.
A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome
Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar
Mol Cell. Author manuscript; available in PMC 2017 Oct 31.
Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004
PMCID:
PMC5663465
AbstractArticlePDF–2.1M
12.
Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas
Kun Fan, Xiaowen Wang, Jingwen Zhang, Romela Irene Ramos, Haibo Zhang, Chunjie Li, Dan Ye, Jiansheng Kang, Diego M. Marzese, Dave S. B. Hoon, Wei Hua
Sci Rep. 2017; 7: 7079. Published online 2017 Aug 1. doi: 10.1038/s41598-017-07124-9
PMCID:
PMC5539284
AbstractArticlePDF–1.2M
13.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
14.
The neuroprotective agent CNTF decreases neuronal metabolites in the rat striatum: an in vivo multimodal magnetic resonance imaging study
Maria-Angeles Carrillo-de Sauvage, Julien Flament, Yann Bramoulle, Lucile Ben Haim, Martine Guillermier, Aurélie Berniard, Gwennaëlle Aurégan, Diane Houitte, Emmanuel Brouillet, Gilles Bonvento, Philippe Hantraye, Julien Valette, Carole Escartin
J Cereb Blood Flow Metab. 2015 Jun; 35(6): 917–921. Published online 2015 Apr 1. doi: 10.1038/jcbfm.2015.48
PMCID:
PMC4640256
AbstractArticlePDF–332K
15.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
16.
The Amino Acid Exchange R28E in Ciliary Neurotrophic Factor (CNTF) Abrogates Interleukin-6 Receptor-dependent but Retains CNTF Receptor-dependent Signaling via Glycoprotein 130 (gp130)/Leukemia Inhibitory Factor Receptor (LIFR)
Eva-Maria Wagener, Matthias Aurich, Samadhi Aparicio-Siegmund, Doreen M. Floss, Christoph Garbers, Kati Breusing, Björn Rabe, Ralf Schwanbeck, Joachim Grötzinger, Stefan Rose-John, Jürgen Scheller
J Biol Chem. 2014 Jun 27; 289(26): 18442–18450. Published online 2014 May 6. doi: 10.1074/jbc.M114.568857
PMCID:
PMC4140248
AbstractArticlePDF–1.5M
17.
Crosstalk between KLF4 and STAT3 regulates axon regeneration
Song Qin, Yuhua Zou, Chun-Li Zhang
Nat Commun. Author manuscript; available in PMC 2013 Dec 19.
Published in final edited form as: Nat Commun. 2013; 4: 2633. doi: 10.1038/ncomms3633
PMCID:
PMC3867821
AbstractArticlePDF–1.6M
18.
CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Müller glial cells
Kun Do Rhee, Steven Nusinowitz, Kevin Chao, Fei Yu, Dean Bok, Xian-Jie Yang
Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47): E4520–E4529. Published online 2013 Nov 4. doi: 10.1073/pnas.1303604110
PMCID:
PMC3839707
AbstractArticlePDF–3.3M
19.
Up-regulation of Ciliary Neurotrophic Factor in Astrocytes by Aspirin: IMPLICATIONS FOR REMYELINATION IN MULTIPLE SCLEROSIS
Khushbu K. Modi, Michael Sendtner, Kalipada Pahan
J Biol Chem. 2013 Jun 21; 288(25): 18533–18545. Published online 2013 May 7. doi: 10.1074/jbc.M112.447268
PMCID:
PMC3689994
AbstractArticlePDF–2.6M
20.
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Ken Y Hui, James C Lee, L Philip Schumm, Yashoda Sharma, Carl A Anderson, Jonah Essers, Mitja Mitrovic, Kaida Ning, Isabelle Cleynen, Emilie Theatre, Sarah L Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean-Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N Ananthakrishnan, Vibeke Andersen, Jane M Andrews, Leonard Baidoo, Tobias Balschun, Peter A Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk De Jong, Kathy L Devaney, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette R Ferguson, Denis Franchimont, Karin Fransen, Richard Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H Karlsen, Limas Kupcinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C Lawrance, Charlie W Lees, Edouard Louis, Gillian Mahy, John Mansfield, Angharad R Morgan, Craig Mowat, William Newman, Orazio Palmieri, Cyriel Y Ponsioen, Uros Potocnik, Natalie J Prescott, Miguel Regueiro, Jerome I Rotter, Richard K Russell, Jeremy D Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A Simms, Jurgita Sventoraityte, Stephan R Targan, Kent D Taylor, Mark Tremelling, Hein W Verspaget, Martine De Vos, Cisca Wijmenga, David C Wilson, Juliane Winkelmann, Ramnik J Xavier, Sebastian Zeissig, Bin Zhang, Clarence K Zhang, Hongyu Zhao, The International IBD Genetics Consortium, Mark S Silverberg, Vito Annese, Hakon Hakonarson, Steven R Brant, Graham Radford-Smith, Christopher G Mathew, John D Rioux, Eric E Schadt, Mark J Daly, Andre Franke, Miles Parkes, Severine Vermeire, Jeffrey C Barrett, Judy H Cho
Nature. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Nature. 2012 Nov 1; 491(7422): 119–124. doi: 10.1038/nature11582
PMCID:
PMC3491803
AbstractArticlePDF–706K

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