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Select item 97030781.

Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions

Katharina M. Glaser, Teresa K. Tarrant, Tim Lämmermann

Front Immunol. 2022; 13: 1039803. Published online 2022 Nov 14. doi: 10.3389/fimmu.2022.1039803

PMCID:: PMC9703078

Abstract Article PDF–20M

Select item 95261582.

G protein–coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin

Matthew J. Varney, Wouter Steyaert, Paul J. Coucke, Joris R. Delanghe, David E. Uehling, Babu Joseph, Richard Marcellus, Rima Al-awar, Jeffrey L. Benovic

J Biol Chem. 2022 Oct; 298(10): 102421. Published online 2022 Aug 25. doi: 10.1016/j.jbc.2022.102421

PMCID:: PMC9526158

Abstract Article PDF–2.1M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 73121694.

Role of GRK6 in the Regulation of Platelet Activation through Selective G Protein-Coupled Receptor (GPCR) Desensitization

Preeti Kumari Chaudhary, Sanggu Kim, Youngheun Jee, Seung-Hun Lee, Kyung-Mee Park, Soochong Kim

Int J Mol Sci. 2020 Jun; 21(11): 3932. Published online 2020 May 30. doi: 10.3390/ijms21113932

PMCID:: PMC7312169

Abstract Article PDF–1.9M

Select item 71882905.

S-Nitrosylation of G protein-coupled receptor kinase 6 and Casein kinase 2 alpha modulates their kinase activity toward alpha-synuclein phosphorylation in an animal model of Parkinson’s disease

Weiwei Wu, Chun Chau Sung, Peichun Yu, Jiahua Li, Kenny K. K. Chung

PLoS One. 2020; 15(4): e0232019. Published online 2020 Apr 28. doi: 10.1371/journal.pone.0232019

Correction in:: PLoS One. 2020; 15(6): e0235296.

PMCID:: PMC7188290

Abstract Article PDF–3.1M

Select item 66335646.

Low Nociceptor GRK2 Prolongs Prostaglandin E₂ Hyperalgesia via Biased cAMP Signaling to Epac/Rap1, Protein Kinase Cε, and MEK/ERK

Niels Eijkelkamp, Huijing Wang, Anibal Garza-Carbajal, Hanneke L. D. M. Willemen, Fried J. Zwartkruis, John N. Wood, Robert Dantzer, Keith W. Kelley, Cobi J. Heijnen, Annemieke Kavelaars

J Neurosci. 2010 Sep 22; 30(38): 12806–12815. doi: 10.1523/JNEUROSCI.3142-10.2010

PMCID:: PMC6633564

Abstract Article PDF–3.5M

Select item 65849467.

Chemerin-Activated Functions of CMKLR1 are Regulated by G Protein-Coupled Receptor Kinase 6 (GRK6) and β-Arrestin 2 in Inflammatory Macrophages

D. Stephen Serafin, Brittney Allyn, Maria F. Sassano, Roman G. Timoshchenko, Daniel Mattox, Jaime M. Brozowski, David P. Siderovski, Young K. Truong, Denise Esserman, Teresa K. Tarrant, Matthew J. Billard

Mol Immunol. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Mol Immunol. 2019 Feb; 106: 12–21. Published online 2018 Dec 18. doi: 10.1016/j.molimm.2018.12.016

PMCID:: PMC6584946

Abstract Article PDF–1021K

Select item 61788058.

G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts

Antonietta Franco, Lihong Zhang, Scot J. Matkovich, Attila Kovacs, Gerald W Dorn, II

J Mol Cell Cardiol. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: J Mol Cell Cardiol. 2018 Aug; 121: 60–68. Published online 2018 Jun 30. doi: 10.1016/j.yjmcc.2018.06.009

PMCID:: PMC6178805

Abstract Article PDF–1.1M

Select item 59405199.

β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling

Jian-peng Teoh, Ahmed S. Bayoumi, Tatsuya Aonuma, Yanyan Xu, John A. Johnson, Huabo Su, Neal L. Weintraub, Yaoliang Tang, Il-man Kim

J Mol Cell Cardiol. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: J Mol Cell Cardiol. 2018 May; 118: 225–236. Published online 2018 Apr 6. doi: 10.1016/j.yjmcc.2018.04.001

PMCID:: PMC5940519

Abstract Article PDF–1.3M

Select item 579213810.

Role of G protein-coupled receptor kinase-6 in Escherichia coli lung infection model in mice

Taehyung Lee, Nandakumar Packiriswamy, Eunhee Lee, Peter C. Lucas, Laura R. McCabe, Narayanan Parameswaran

Physiol Genomics. 2017 Nov 1; 49(11): 682–689. Published online 2017 Sep 22. doi: 10.1152/physiolgenomics.00066.2017

PMCID:: PMC5792138

Abstract Article

Select item 572679011.

MIGRATING MYELOID CELLS SENSE TEMPORAL DYNAMICS OF CHEMOATTRACTANT CONCENTRATIONS

Caren E. Petrie Aronin, Yun Zhao, Justine S. Yoon, Nicole Y. Morgan, Thorsten Prüstel, Ronald N. Germain, Martin Meier-Schellersheim

Immunity. Author manuscript; available in PMC 2018 Nov 21.

Published in final edited form as: Immunity. 2017 Nov 21; 47(5): 862–874.e3. doi: 10.1016/j.immuni.2017.10.020

PMCID:: PMC5726790

Abstract Article PDF–1.0M

Select item 526090412.

GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal

Qiumin Le, Wenqing Yao, Yuejun Chen, Biao Yan, Cao Liu, Man Yuan, Yuqing Zhou, Lan Ma

Cell Death Dis. 2016 Nov; 7(11): e2478. Published online 2016 Nov 24. doi: 10.1038/cddis.2016.377

PMCID:: PMC5260904

Abstract Article PDF–1.1M

Select item 488778713.

SCF/c-kit transactivates CXCR4-serine 339 phosphorylation through G protein-coupled receptor kinase 6 and regulates cardiac stem cell migration

Ke Zuo, Dong Kuang, Ying Wang, Yanli Xia, Weilin Tong, Xiaoyan Wang, Yaobin Chen, Yaqi Duan, Guoping Wang

Sci Rep. 2016; 6: 26812. Published online 2016 Jun 1. doi: 10.1038/srep26812

PMCID:: PMC4887787

Abstract Article PDF–1.8M

Select item 481447514.

Enhanced Uterine Contractility and Stillbirth in Mice Lacking G Protein-Coupled Receptor Kinase 6 (GRK6): Implications for Oxytocin Receptor Desensitization

Chad A. Grotegut, Lan Mao, Stephanie L. Pierce, Geeta K. Swamy, R. Phillips Heine, Amy P. Murtha

Mol Endocrinol. 2016 Apr; 30(4): 455–468. Published online 2016 Feb 17. doi: 10.1210/me.2015-1147

PMCID:: PMC4814475

Abstract Article

Select item 395096715.

G-protein-coupled receptor kinase-6 interacts with Activator of G-protein signaling-3 to regulate CXCR2-mediated cellular functions

Vandana Singh, Sandeep K. Raghuwanshi, Nikia Smith, Elizabeth J. Rivers, Ricardo M. Richardson

J Immunol. Author manuscript; available in PMC 2015 Mar 1.

Published in final edited form as: J Immunol. 2014 Mar 1; 192(5): 2186–2194. Published online 2014 Feb 7. doi: 10.4049/jimmunol.1301875

PMCID:: PMC3950967

Abstract Article PDF–1.4M

Select item 364698016.

GRK6 deficiency promotes angiogenesis, tumor progression and metastasis

Sandeep K. Raghuwanshi, Nikia Smith, Elizabeth, J. Rivers, Ariel J. Thomas, Natalie Sutton, Yuhui Hu, Somnath Mukhopadhyay, Xiaoxin L. Chen, TinChung Leung, Ricardo M. Richardson

J Immunol. Author manuscript; available in PMC 2014 May 15.

Published in final edited form as: J Immunol. 2013 May 15; 190(10): 5329–5336. Published online 2013 Apr 15. doi: 10.4049/jimmunol.1202058

PMCID:: PMC3646980

Abstract Article PDF–3.7M

Select item 358672217.

GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance

Michio Nakaya, Mitsuru Tajima, Hidetaka Kosako, Takeo Nakaya, Akiko Hashimoto, Kenji Watari, Hiroaki Nishihara, Mina Ohba, Shiori Komiya, Naoki Tani, Motohiro Nishida, Hisaaki Taniguchi, Yoji Sato, Mitsuru Matsumoto, Makoto Tsuda, Masahiko Kuroda, Kazuhide Inoue, Hitoshi Kurose

Nat Commun. 2013 Feb 26; 4: 1532. Published online 2013 Feb 26. doi: 10.1038/ncomms2540

PMCID:: PMC3586722

Abstract Article PDF–1.8M

Select item 343698618.

The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions

Sandeep K. Raghuwanshi, Yingjun Su, Vandana Singh, Katherine Hayes, Ann Richmond, Ricardo M. Richardson

J Immunol. Author manuscript; available in PMC 2013 Sep 15.

Published in final edited form as: J Immunol. 2012 Sep 15; 189(6): 2824–2832. Published online 2012 Aug 6. doi: 10.4049/jimmunol.1201114

PMCID:: PMC3436986

Abstract Article PDF–5.0M

Select item 329314819.

The role of GRK6 in animal models of Parkinson's Disease and L-DOPA treatment

Francesca Managò, Stefano Espinoza, Ali Salahpour, Tatyana D. Sotnikova, Marc G. Caron, Richard T. Premont, Raul R. Gainetdinov

Sci Rep. 2012; 2: 301. Published online 2012 Mar 5. doi: 10.1038/srep00301

PMCID:: PMC3293148

Abstract Article PDF–599K

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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