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Items: 1 to 20 of 25

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
PNKP is required for maintaining the integrity of progenitor cell populations in adult mice
Wisoo Shin, Whitney Alpaugh, Laura J Hallihan, Sarthak Sinha, Emilie Crowther, Gary R Martin, Teresa Scheidl-Yee, Xiaoyan Yang, Grace Yoon, Taylor Goldsmith, Nelson D Berger, Luiz GN de Almeida, Antoine Dufour, Ina Dobrinski, Michael Weinfeld, Frank R Jirik, Jeff Biernaskie
Life Sci Alliance. 2021 Sep; 4(9): e202000790. Published online 2021 Jul 5. doi: 10.26508/lsa.202000790
PMCID:
PMC8321660
AbstractArticlePDF–3.8M
3.
XRCC1-mediated repair of strand breaks independent of PNKP binding
Julie K. Horton, Donna F. Stefanick, Ming-Lang Zhao, Agnes K. Janoshazi, Natalie R. Gassman, Hannah J. Seddon, Samuel H. Wilson
DNA Repair (Amst) Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: DNA Repair (Amst). 2017 Dec; 60: 52–63. Published online 2017 Oct 19. doi: 10.1016/j.dnarep.2017.10.007
PMCID:
PMC5696015
AbstractArticlePDF–1.1M
4.
Characterization of DNA substrate binding to the phosphatase domain of the DNA repair enzyme, PNKP
Zahra Havali-Shahriari, Michael Weinfeld, J. N. Mark Glover
Biochemistry. Author manuscript; available in PMC 2017 Jun 13.
Published in final edited form as: Biochemistry. 2017 Mar 28; 56(12): 1737–1745. Published online 2017 Mar 15. doi: 10.1021/acs.biochem.6b01236
PMCID:
PMC5469602
AbstractArticlePDF–950K
5.
Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury
Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355
PMCID:
PMC5045200
AbstractArticlePDF–2.9M
6.
The structural basis for substrate recognition by mammalian polynucleotide kinase 3’ phosphatase
Fernando Garces, Laurence H. Pearl, Antony W. Oliver
Mol Cell. Author manuscript; available in PMC 2016 Apr 4.
Published in final edited form as: Mol Cell. 2011 Nov 4; 44(3): 385–396. doi: 10.1016/j.molcel.2011.08.036
PMCID:
PMC4820033
AbstractArticlePDF–2.9M
7.
FBXW7 facilitates non-homologous end-joining via K63-linked polyubiquitylation of XRCC4
Qiang Zhang, David Karnak, Mingjia Tan, Theodore S. Lawrence, Meredith A. Morgan, Yi Sun
Mol Cell. Author manuscript; available in PMC 2017 Feb 4.
Published in final edited form as: Mol Cell. 2016 Feb 4; 61(3): 419–433. Published online 2016 Jan 7. doi: 10.1016/j.molcel.2015.12.010
PMCID:
PMC4744117
AbstractArticlePDF–2.6M
8.
Polynucleotide kinase–phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability
Mikio Shimada, Lavinia C Dumitrache, Helen R Russell, Peter J McKinnon
EMBO J. 2015 Oct 1; 34(19): 2465–2480. Published online 2015 Aug 19. doi: 10.15252/embj.201591363
PMCID:
PMC4601665
AbstractArticlePDF–7.3M
9.
Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells
Paulina A. Latos, Angela Goncalves, David Oxley, Hisham Mohammed, Ernest Turro, Myriam Hemberger
Nat Commun. 2015; 6: 7776. Published online 2015 Jul 24. doi: 10.1038/ncomms8776
PMCID:
PMC4525203
AbstractArticlePDF–1.9M
10.
Aberrant Topoisomerase-1-DNA Lesions are Pathogenic in Neurodegenerative Genome Instability Syndromes
Sachin Katyal, Youngsoo Lee, Karin C. Nitiss, Susanna M. Downing, Yang Li, Mikio Shimada, Jingfeng Zhao, Helen R. Russell, John H. J. Petrini, John L. Nitiss, Peter J. McKinnon
Nat Neurosci. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Nat Neurosci. 2014 Jun; 17(6): 813–821. Published online 2014 May 4. doi: 10.1038/nn.3715
PMCID:
PMC4074009
AbstractArticlePDF–2.2M
11.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
12.
Pol β associated complex and base excision repair factors in mouse fibroblasts
Rajendra Prasad, Jason G. Williams, Esther W. Hou, Samuel H. Wilson
Nucleic Acids Res. 2012 Dec; 40(22): 11571–11582. Published online 2012 Oct 5. doi: 10.1093/nar/gks898
PMCID:
PMC3526277
AbstractArticlePDF–2.3M
13.
Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress
Jason L. Parsons, Svetlana V. Khoronenkova, Irina I. Dianova, Nicola Ternette, Benedikt M. Kessler, Pran K. Datta, Grigory L. Dianov
Nucleic Acids Res. 2012 Dec; 40(22): 11404–11415. Published online 2012 Oct 5. doi: 10.1093/nar/gks909
PMCID:
PMC3526271
AbstractArticlePDF–2.4M
14.
Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates
Nicolas Coquelle, Zahra Havali-Shahriari, Nina Bernstein, Ruth Green, J. N. Mark Glover
Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52): 21022-21027. Published online 2011 Dec 14. doi: 10.1073/pnas.1112036108
PMCID:
PMC3248541
AbstractArticlePDF–1.7M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells
Debbie L.C. van den Berg, Tim Snoek, Nick P. Mullin, Adam Yates, Karel Bezstarosti, Jeroen Demmers, Ian Chambers, Raymond A. Poot
Cell Stem Cell. 2010 Apr 2; 6(4): 369–381. doi: 10.1016/j.stem.2010.02.014
PMCID:
PMC2860243
AbstractArticle
17.
Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase
N. K. Bernstein, M. Hammel, R. S. Mani, M. Weinfeld, M. Pelikan, J. A. Tainer, J. N. M. Glover
Nucleic Acids Res. 2009 Oct; 37(18): 6161–6173. Published online 2009 Aug 11. doi: 10.1093/nar/gkp597
PMCID:
PMC2764422
AbstractArticlePDF–2.4M
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K

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