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Select item 115264771.

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development

Timothy J. Mead, Sumit Bhutada, Simon J. Foulcer, Niccolò Peruzzi, Courtney M. Nelson, Deborah E. Seifert, Jonathan Larkin, Karin Tran-Lundmark, Jorge Filmus, Suneel S. Apte

Matrix Biol. Author manuscript; available in PMC 2024 Oct 31.

Published in final edited form as: Matrix Biol. 2024 Aug; 131: 1–16. Published online 2024 May 13. doi: 10.1016/j.matbio.2024.05.003

PMCID:: PMC11526477

Abstract Article PDF–5.2M

Select item 113032552.

Astrocytes require perineuronal nets to maintain synaptic homeostasis in mice

Bhanu P. Tewari, AnnaLin M. Woo, Courtney E. Prim, Lata Chaunsali, Dipan C. Patel, Ian F. Kimbrough, Kaliroi Engel, Jack L. Browning, Susan L. Campbell, Harald Sontheimer

Nat Neurosci. 2024; 27(8): 1475–1488. Published online 2024 Jul 17. doi: 10.1038/s41593-024-01714-3

PMCID:: PMC11303255

Abstract Article PDF–22M

Select item 112772173.

Analysis of the Actions of RARγ Agonists on Growing Osteochondromas in a Mouse Model

Sonia A. Garcia, Kimberly Wilson, Ningfeng Tang, Hongying Tian, Takeshi Oichi, Aruni T. Gunawardena, Michael Chorny, Ivan S. Alferiev, John E. Herzenberg, Vincent Y. Ng, Masahiro Iwamoto, Motomi Enomoto-Iwamoto

Int J Mol Sci. 2024 Jul; 25(14): 7610. Published online 2024 Jul 11. doi: 10.3390/ijms25147610

PMCID:: PMC11277217

Abstract Article PDF–3.9M

Select item 111604724.

Nuclear factor κB overactivation in the intervertebral disc leads to macrophage recruitment and severe disc degeneration

Kevin G. Burt, Min Kyu M. Kim, Dan C. Viola, Adam C. Abraham, Nadeen O. Chahine

Sci Adv. 2024 Jun 7; 10(23): eadj3194. Published online 2024 Jun 7. doi: 10.1126/sciadv.adj3194

PMCID:: PMC11160472

Abstract Article PDF–28M

Select item 111467765.

Lecticans: organizers of the brain extracellular matrix

Y. Yamaguchi

Cell Mol Life Sci. 2000 Feb; 57(2): 276–289. doi: 10.1007/PL00000690

PMCID:: PMC11146776

Abstract Article PDF–1.5M

Select item 110188626.

Nerve growth factor receptor limits inflammation to promote remodeling and repair of osteoarthritic joints

Lan Zhao, Yumei Lai, Hongli Jiao, Jian Huang

Nat Commun. 2024; 15: 3225. Published online 2024 Apr 15. doi: 10.1038/s41467-024-47633-6

PMCID:: PMC11018862

Abstract Article PDF–5.2M

Select item 110082687.

Deficiency of Cbfβ in articular cartilage leads to osteoarthritis-like phenotype through Hippo/Yap, TGFβ, and Wnt/β-catenin signaling pathways

Yan Zhang, Huiwen Chen, Jinjin Wu, Abigail McVicar, Yilin Chen, Jiacan Su, Yi-Ping Li, Wei Chen

Int J Biol Sci. 2024; 20(6): 1965–1977. Published online 2024 Mar 11. doi: 10.7150/ijbs.90250

PMCID:: PMC11008268

Abstract Article PDF–16M

Select item 110055138.

Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality

Aki Ushiki, Rory R. Sheng, Yichi Zhang, Jingjing Zhao, Mai Nobuhara, Elizabeth Murray, Xin Ruan, Jonathan J. Rios, Carol A. Wise, Nadav Ahituv

Cell Rep. Author manuscript; available in PMC 2024 Apr 10.

Published in final edited form as: Cell Rep. 2024 Mar 26; 43(3): 113907. Published online 2024 Mar 8. doi: 10.1016/j.celrep.2024.113907

PMCID:: PMC11005513

Abstract Article PDF–1.6M

Select item 109176609.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 1089525910.

Skeletal growth is enhanced by a shared role for SOX8 and SOX9 in promoting reserve chondrocyte commitment to columnar proliferation

Arnaud N. Molin, Romain Contentin, Marco Angelozzi, Anirudha Karvande, Ranjan Kc, Abdul Haseeb, Chantal Voskamp, Charles de Charleroy, Véronique Lefebvre

Proc Natl Acad Sci U S A. 2024 Feb 20; 121(8): e2316969121. Published online 2024 Feb 12. doi: 10.1073/pnas.2316969121

PMCID:: PMC10895259

Abstract Article PDF–17M

Select item 1079415111.

Na_v1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis

Wenyu Fu, Dmytro Vasylyev, Yufei Bi, Mingshuang Zhang, Guodong Sun, Asya Khleborodova, Guiwu Huang, Libo Zhao, Renpeng Zhou, Yonggang Li, Shujun Liu, Xianyi Cai, Wenjun He, Min Cui, Xiangli Zhao, Aubryanna Hettinghouse, Julia Good, Ellen Kim, Eric Strauss, Philipp Leucht, Ran Schwarzkopf, Edward X. Guo, Jonathan Samuels, Wenhuo Hu, Mukundan Attur, Stephen G. Waxman, Chuan-ju Liu

Nature. 2024; 625(7995): 557–565. Published online 2024 Jan 3. doi: 10.1038/s41586-023-06888-7

PMCID:: PMC10794151

Abstract Article PDF–85M

Select item 1079041712.

Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity

Angela Ruscitto, Peng Chen, Ikue Tosa, Ziyi Wang, Gan Zhou, Ingrid Safina, Ran Wei, Mallory M Morel, Alia Koch, Michael Forman, Gwendolyn Reeve, Michael K Lecholop, Marshall Wilson, Daniel Bonthius, Mo Chen, Mitsuaki Ono, Timothy C Wang, Hai Yao, Mildred C Embree

Cell Stem Cell. Author manuscript; available in PMC 2024 Sep 7.

Published in final edited form as: Cell Stem Cell. 2023 Sep 7; 30(9): 1179–1198.e7. doi: 10.1016/j.stem.2023.08.004

PMCID:: PMC10790417

Abstract Article PDF–6.0M

Select item 1066297213.

Myocardial equation M1

-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation

Yidong Wang, Pengfei Lu, Bingruo Wu, Dario F. Riascos-Bernal, Nicholas E.S. Sibinga, Tomas Valenta, Konrad Basler, Bin Zhou

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Nov 21.

Published in final edited form as: J Mol Cell Cardiol. 2018 Oct; 123: 150–158. Published online 2018 Sep 8. doi: 10.1016/j.yjmcc.2018.09.001

PMCID:: PMC10662972

Abstract Article PDF–2.2M

Select item 1064539914.

Insulin-Like Growth Factor-I Is Essential for Embryonic Bone Development

Yongmei Wang, Shigeki Nishida, Takeshi Sakata, Hashem Z. Elalieh, Wenhan Chang, Bernard P. Halloran, Steven B. Doty, Daniel D. Bikle

Endocrinology. Author manuscript; available in PMC 2023 Nov 14.

Published in final edited form as: Endocrinology. 2006 Oct; 147(10): 4753–4761. Published online 2006 Jul 20. doi: 10.1210/en.2006-0196

PMCID:: PMC10645399

Abstract Article PDF–2.8M

Select item 1054730015.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 1039049216.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7