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Select item 113333791.

Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for β-Cell Function During Aging

Jose A. Ortiz, Nadiah Ghazalli, Kassandra Lopez, Jeffrey Rawson, Erika M. McCown, Eunjin Oh, Jose M. Irimia, Kevin Jou, Jacob Mares, Min-Hsuan Chen, Xiwei Wu, Heather N. Zook, Janine C. Quijano, Neslihan Erdem, Anahy Lizarraga, Fouad Kandeel, Patrick T. Fueger, Debbie C. Thurmond, Hsun Teresa Ku

Diabetes. 2024 Sep; 73(9): 1447–1461. Published online 2024 Jun 21. doi: 10.2337/db23-0490

PMCID:: PMC11333379

Abstract Article PDF–209M

Select item 101386972.

The Forms of the Lectin Tff2 Differ in the Murine Stomach and Pancreas: Indications for Different Molecular Functions

Eva B. Znalesniak, Aikaterini Laskou, Franz Salm, Katharina Haupenthal, Sönke Harder, Hartmut Schlüter, Werner Hoffmann

Int J Mol Sci. 2023 Apr; 24(8): 7059. Published online 2023 Apr 11. doi: 10.3390/ijms24087059

PMCID:: PMC10138697

Abstract Article PDF–3.4M

Select item 99251163.

TFF2 deficiency exacerbates weight loss and alters immune cell and cytokine profiles in DSS colitis, and this cannot be rescued by wild-type bone marrow

Louise M. Judd, Heather V. Chalinor, Anna Walduck, Daniel I. Pavlic, Jan Däbritz, Zinaida Dubeykovskaya, Timothy C. Wang, Trevelyan R. Menheniott, Andrew S. Giraud

Am J Physiol Gastrointest Liver Physiol. 2015 Jan 1; 308(1): G12–G24. Published online 2014 Oct 16. doi: 10.1152/ajpgi.00172.2014

PMCID:: PMC9925116

Abstract Article

Select item 82675504.

Trefoil factor 2 secreted from damaged hepatocytes activates hepatic stellate cells to induce fibrogenesis

Bichen Zhang, Kalina Lapenta, Qi Wang, Jin Hyun Nam, Dongjun Chung, Marie E. Robert, Michael H. Nathanson, Xiaoyong Yang

J Biol Chem. 2021 Jul; 297(1): 100887. Published online 2021 Jun 17. doi: 10.1016/j.jbc.2021.100887

PMCID:: PMC8267550

Abstract Article PDF–2.9M

Select item 68262375.

Trefoil factor 2 activation of CXCR4 requires calcium mobilization to drive epithelial repair in gastric organoids

Kristen A. Engevik, Hikaru Hanyu, Andrea L. Matthis, Tongli Zhang, Mark R. Frey, Yusuke Oshima, Eitaro Aihara, Marshall H. Montrose

J Physiol. 2019 May 15; 597(10): 2673–2690. Published online 2019 Apr 14. doi: 10.1113/JP277259

PMCID:: PMC6826237

Abstract Article PDF–1.8M

Select item 63673806.

Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis

Koji Hirata, Sota Kodama, Yasuhiro Nakano, Yasuko Minaki-Nakagawa, Yoshiki Aoyama, Morito Sakikubo, Toshihiko Goto, Masahiro Yoshida, Toshihiko Masui, Takuya Yamamoto, Shinji Uemoto, Yoshiya Kawaguchi

Sci Rep. 2019; 9: 1636. Published online 2019 Feb 7. doi: 10.1038/s41598-018-38062-9

PMCID:: PMC6367380

Abstract Article PDF–6.8M

Select item 63011017.

Macrophages promote epithelial proliferation following infectious and non-infectious lung injury through a Trefoil factor 2-dependent mechanism

Li-Yin Hung, Debasish Sen, Taylor K. Oniskey, Jeremey Katzen, Noam A. Cohen, Andrew E. Vaughan, Wildaliz Nieves, Anatoly Urisman, Michael F. Beers, Matthew F. Krummel, De’Broski R. Herbert

Mucosal Immunol. Author manuscript; available in PMC 2019 Apr 18.

Published in final edited form as: Mucosal Immunol. 2019 Jan; 12(1): 64–76. Published online 2018 Oct 18. doi: 10.1038/s41385-018-0096-2

PMCID:: PMC6301101

Abstract Article PDF–2.6M

Select item 59067398.

Trefoil Factor 2 Promotes Type 2 Immunity and Lung Repair through Intrinsic Roles in Hematopoietic and Nonhematopoietic Cells

Li-Yin Hung, Taylor K. Oniskey, Debasish Sen, Matthew F. Krummel, Andrew E. Vaughan, Noam A. Cohen, De'Broski R. Herbert

Am J Pathol. 2018 May; 188(5): 1161–1170. doi: 10.1016/j.ajpath.2018.01.020

PMCID:: PMC5906739

Abstract Article

Select item 59025909.

Id2 Determines Intestinal Identity through Repression of the Foregut Transcription Factor Irx5

Kentaro Mori, Harumi Nakamura, Hisanori Kurooka, Hitoshi Miyachi, Kota Tamada, Manabu Sugai, Toru Takumi, Yoshifumi Yokota

Mol Cell Biol. 2018 May 1; 38(9): e00250-17. Prepublished online 2018 Feb 20. Published online 2018 Apr 16. doi: 10.1128/MCB.00250-17

PMCID:: PMC5902590

Abstract Article PDF–4.4M

Select item 474292010.

Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer

Zina Dubeykovskaya, Yiling Si, Xiaowei Chen, Daniel L. Worthley, Bernhard W. Renz, Aleksandra M. Urbanska, Yoku Hayakawa, Ting Xu, C. Benedikt Westphalen, Alexander Dubeykovskiy, Duan Chen, Richard A. Friedman, Samuel Asfaha, Karan Nagar, Yagnesh Tailor, Sureshkumar Muthupalani, James G. Fox, Jan Kitajewski, Timothy C. Wang

Nat Commun. 2016; 7: 10517. Published online 2016 Feb 4. doi: 10.1038/ncomms10517

PMCID:: PMC4742920

Abstract Article PDF–1.5M

Select item 397056811.

Helicobacter pylori Infection Promotes Methylation and Silencing of Trefoil Factor 2, Leading to Gastric Tumor Development in Mice and Humans

Anthony J. Peterson, Trevelyan R. Menheniott, Louise O’Connor, Anna K. Walduck, James G. Fox, Kazuyuki Kawakami, Toshinari Minamoto, Eng Kok Ong, Timothy C. Wang, Louise M. Judd, Andrew S. Giraud

Gastroenterology. Author manuscript; available in PMC 2014 Mar 31.

Published in final edited form as: Gastroenterology. 2010 Dec; 139(6): 2005–2017. Published online 2010 Aug 27. doi: 10.1053/j.gastro.2010.08.043

PMCID:: PMC3970568

Abstract Article PDF–5.4M

Select item 368665212.

In vivo action of trefoil factor 2 (TFF2) to speed gastric repair is independent of cyclooxygenase

Lin Xue, Eitaro Aihara, Daniel K. Podolsky, Timothy C. Wang, Marshall H. Montrose

Gut. Author manuscript; available in PMC 2013 Jun 19.

Published in final edited form as: Gut. 2010 Sep; 59(9): 1184–1191. Published online 2010 Jun 29. doi: 10.1136/gut.2009.205625

PMCID:: PMC3686652

Abstract Article PDF–1.5M

Select item 362564413.

Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm

Jianwen Que, Tadashi Okubo, James R. Goldenring, Ki-Taek Nam, Reiko Kurotani, Edward E. Morrisey, Olena Taranova, Larysa H. Pevny, Brigid L. M. Hogan

Development. Author manuscript; available in PMC 2013 Apr 14.

Published in final edited form as: Development. 2007 Jul; 134(13): 2521–2531. Published online 2007 May 23. doi: 10.1242/dev.003855

PMCID:: PMC3625644

Abstract Article PDF–3.0M

Select item 343693714.

Trefoil factor 2 negatively regulates Type 1 immunity against Toxoplasma gondii

Cortez McBerry, Charlotte E. Egan, Reena Rani, Yanfen Yang, David Wu, Nicholas Boespflug, Louis Boon, Barbara Butcher, Julie Mirpuri, Simon P. Hogan, Eric Y. Denkers, Julio Aliberti, De’Broski R. Herbert

J Immunol. Author manuscript; available in PMC 2013 Sep 15.

Published in final edited form as: J Immunol. 2012 Sep 15; 189(6): 3078–3084. Published online 2012 Aug 15. doi: 10.4049/jimmunol.1103374

PMCID:: PMC3436937

Abstract Article PDF–2.5M

Select item 338322715.

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2

Shanru Li, Yi Wang, Yuzhen Zhang, Min Min Lu, Francesco J. DeMayo, Joseph D. Dekker, Philip W. Tucker, Edward E. Morrisey

Development. 2012 Jul 15; 139(14): 2500–2509. doi: 10.1242/dev.079699

PMCID:: PMC3383227

Abstract Article

Select item 330222916.

Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

Marsha Wills-Karp, Reena Rani, Krista Dienger, Ian Lewkowich, James G. Fox, Charles Perkins, Lauren Lewis, Fred D. Finkelman, Dirk E. Smith, Paul J. Bryce, Evelyn A. Kurt-Jones, Timothy C. Wang, Umasundari Sivaprasad, Gurjit K. Hershey, De’Broski R. Herbert

J Exp Med. 2012 Mar 12; 209(3): 607–622. doi: 10.1084/jem.20110079

PMCID:: PMC3302229

Abstract Article PDF–3.5M

Select item 320747517.

Trefoil Factor 2 Requires Na/H Exchanger 2 Activity to Enhance Mouse Gastric Epithelial Repair

Lin Xue, Eitaro Aihara, Timothy C. Wang, Marshall H. Montrose

J Biol Chem. 2011 Nov 4; 286(44): 38375–38382. Published online 2011 Sep 7. doi: 10.1074/jbc.M111.268219

PMCID:: PMC3207475

Abstract Article PDF–1.4M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 307457719.

Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP- and HGF-mediated signaling networks

Nikki Cheng, Neil A Bhowmick, Anna Chytil, Agnieszka E Gorksa, Kimberly A Brown, Rebecca Muraoka, Carlos L Arteaga, Eric G Neilson, Simon W Hayward, Harold L Moses

Oncogene. Author manuscript; available in PMC 2011 Apr 12.

Published in final edited form as: Oncogene. 2005 Jul 28; 24(32): 5053–5068. doi: 10.1038/sj.onc.1208685