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Select item 106655741.

Protein modification regulated autophagy in Bombyx mori and Drosophila melanogaster

Wenmei Wu, Luobin Lin, Yuntao Zhao, Huaqin Li, Rongxin Zhang

Front Physiol. 2023; 14: 1281555. Published online 2023 Nov 9. doi: 10.3389/fphys.2023.1281555

PMCID:: PMC10665574

Abstract Article PDF–1.1M

Select item 103686962.

Nutritional stress-induced regulation of microtubule organization and mRNP transport by HDAC1 controlled α-tubulin acetylation

Frank Wippich, Vaishali, Marco L. Hennrich, Anne Ephrussi

Commun Biol. 2023; 6: 776. Published online 2023 Jul 25. doi: 10.1038/s42003-023-05138-w

PMCID:: PMC10368696

Abstract Article PDF–8.8M

Select item 101211743.

CBP and Gcn5 drive zygotic genome activation independently of their catalytic activity

Filippo Ciabrelli, Leily Rabbani, Francesco Cardamone, Fides Zenk, Eva Löser, Melanie A. Schächtle, Marina Mazina, Vincent Loubiere, Nicola Iovino

Sci Adv. 2023 Apr; 9(16): eadf2687. Published online 2023 Apr 21. doi: 10.1126/sciadv.adf2687

PMCID:: PMC10121174

Abstract Article PDF–1.6M

Select item 98941844.

Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila

Ting Miao, Jinoh Kim, Ping Kang, Hideji Fujiwara, Fong-Fu Hsu, Hua Bai

Proc Natl Acad Sci U S A. 2022 Dec 6; 119(49): e2212220119. Published online 2022 Dec 2. doi: 10.1073/pnas.2212220119

PMCID:: PMC9894184

Abstract Article PDF–3.8M

Select item 95904725.

Immunosuppression Induced by Brain-Specific HDAC6 Knockdown Improves Aging Performance in Drosophila melanogaster

Yingying Zhao, Hongwen Xuan, Chao Shen, Peiyi Liu, Jing-Dong J. Han, Wei Yu

Phenomics. 2022 Jun; 2(3): 194–200. Published online 2022 Feb 23. doi: 10.1007/s43657-022-00045-2

PMCID:: PMC9590472

Abstract Article PDF–1.3M

Select item 93364956.

Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain

Mariah Beaver, Bhanu Chandra Karisetty, Haolin Zhang, Akanksha Bhatnagar, Ellen Armour, Visha Parmar, Reshma Brown, Merry Xiang, Felice Elefant

Epigenetics. 2022; 17(7): 786–807. Published online 2021 Aug 9. doi: 10.1080/15592294.2021.1959742

PMCID:: PMC9336495

Abstract Article PDF–3.5M

Select item 90650017.

Pantothenate kinase 2 interacts with PINK1 to regulate mitochondrial quality control via acetyl-CoA metabolism

Yunpeng Huang, Zhihui Wan, Yinglu Tang, Junxuan Xu, Bretton Laboret, Sree Nallamothu, Chenyu Yang, Boxiang Liu, Rongze Olivia Lu, Bingwei Lu, Juan Feng, Jing Cao, Susan Hayflick, Zhihao Wu, Bing Zhou

Nat Commun. 2022; 13: 2412. Published online 2022 May 3. doi: 10.1038/s41467-022-30178-x

PMCID:: PMC9065001

Abstract Article PDF–5.6M

Select item 88439878.

Acetylated α-tubulin K394 regulates microtubule stability to shape the growth of axon terminals

Harriet A. J. Saunders, Dena M. Johnson-Schlitz, Brian V. Jenkins, Peter J. Volkert, Sihui Z. Yang, Jill Wildonger

Curr Biol. Author manuscript; available in PMC 2023 Feb 7.

Published in final edited form as: Curr Biol. 2022 Feb 7; 32(3): 614–630.e5. Published online 2022 Jan 25. doi: 10.1016/j.cub.2021.12.012

PMCID:: PMC8843987

Abstract Article PDF–3.1M

Select item 87005549.

Differential Dose- and Tissue-Dependent Effects of foxo on Aging, Metabolic and Proteostatic Pathways

Maria S. Manola, Sentiljana Gumeni, Ioannis P. Trougakos

Cells. 2021 Dec; 10(12): 3577. Published online 2021 Dec 18. doi: 10.3390/cells10123577

PMCID:: PMC8700554

Abstract Article PDF–17M

Select item 866448610.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 849760611.

ATP-citrate lyase promotes axonal transport across species

Aviel Even, Giovanni Morelli, Silvia Turchetto, Michal Shilian, Romain Le Bail, Sophie Laguesse, Nathalie Krusy, Ariel Brisker, Alexander Brandis, Shani Inbar, Alain Chariot, Frédéric Saudou, Paula Dietrich, Ioannis Dragatsis, Bert Brone, Loïc Broix, Jean-Michel Rigo, Miguel Weil, Laurent Nguyen

Nat Commun. 2021; 12: 5878. Published online 2021 Oct 7. doi: 10.1038/s41467-021-25786-y

Correction in:: Nat Commun. 2021; 12: 6678.

PMCID:: PMC8497606

Abstract Article PDF–5.3M

Select item 836357012.

Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex

Bat-Erdene Jugder, Layla Kamareddine, Paula I Watnick

Immunity. Author manuscript; available in PMC 2022 Aug 10.

Published in final edited form as: Immunity. 2021 Aug 10; 54(8): 1683–1697.e3. Published online 2021 Jun 8. doi: 10.1016/j.immuni.2021.05.017

PMCID:: PMC8363570

Abstract Article PDF–3.4M

Select item 827360013.

Interactions and Feedbacks in E-Cadherin Transcriptional Regulation

Miguel Ramirez Moreno, Przemyslaw A. Stempor, Natalia A. Bulgakova

Front Cell Dev Biol. 2021; 9: 701175. Published online 2021 Jun 28. doi: 10.3389/fcell.2021.701175

PMCID:: PMC8273600

Abstract Article PDF–1.5M

Select item 801257314.

Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism

Ruofan Yu, Xiaohua Cao, Luyang Sun, Jun-yi Zhu, Brian M Wasko, Wei Liu, Emeline Crutcher, Haiying Liu, Myeong Chan Jo, Lidong Qin, Matt Kaeberlein, Zhe Han, Weiwei Dang

Nat Commun. 2021; 12: 1981. Published online 2021 Mar 31. doi: 10.1038/s41467-021-22257-2

PMCID:: PMC8012573

Abstract Article PDF–3.1M

Select item 783109015.

Amyotrophic Lateral Sclerosis Genes in Drosophila melanogaster

Sophie Layalle, Laetitia They, Sarah Ourghani, Cédric Raoul, Laurent Soustelle

Int J Mol Sci. 2021 Jan; 22(2): 904. Published online 2021 Jan 18. doi: 10.3390/ijms22020904

PMCID:: PMC7831090

Abstract Article PDF–3.9M

Select item 782533216.

Epigenetic Regulation of ALS and CMT: A Lesson from Drosophila Models

Masamitsu Yamaguchi, Kentaro Omori, Satoshi Asada, Hideki Yoshida

Int J Mol Sci. 2021 Jan; 22(2): 491. Published online 2021 Jan 6. doi: 10.3390/ijms22020491

PMCID:: PMC7825332

Abstract Article PDF–400K

Select item 773720217.

Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration

Haolin Zhang, Bhanu Chandra Karisetty, Akanksha Bhatnagar, Ellen M. Armour, Mariah Beaver, Tiffany V. Roach, Sina Mortazavi, Shreya Mandloi, Felice Elefant

Mol Cell Neurosci. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Mol Cell Neurosci. 2020 Dec; 109: 103570. Published online 2020 Nov 4. doi: 10.1016/j.mcn.2020.103570

PMCID:: PMC7737202

Abstract Article PDF–2.7M

Select item 758844518.

Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases

Mariah Beaver, Akanksha Bhatnagar, Priyalakshmi Panikker, Haolin Zhang, Renee Snook, Visha Parmar, Gayathri Vijayakumar, Niteesha Betini, Sunya Akhter, Felice Elefant

Sci Rep. 2020; 10: 18265. Published online 2020 Oct 26. doi: 10.1038/s41598-020-75035-3

PMCID:: PMC7588445

Abstract Article PDF–2.9M

Select item 733707119.

Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target

Mark W. Kankel, Anindya Sen, Lei Lu, Marina Theodorou, Douglas N. Dimlich, Alexander McCampbell, Christopher E. Henderson, Neil A. Shneider, Spyros Artavanis-Tsakonas

Genetics. 2020 Jul; 215(3): 747–766. Published online 2020 Apr 28. doi: 10.1534/genetics.119.302985