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Items: 1 to 20 of 34

1.
The social and structural architecture of the yeast protein interactome
André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann
Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5
PMCID:
PMC10700138
AbstractArticlePDF–20M
2.
Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions
Shibai Li, You Yu, Jian Zheng, Victoria Miller-Browne, Zheng Ser, Huihui Kuang, Dinshaw J. Patel, Xiaolan Zhao
Proc Natl Acad Sci U S A. 2023 Nov 7; 120(45): e2310924120. Published online 2023 Oct 30. doi: 10.1073/pnas.2310924120
PMCID:
PMC10636319
AbstractArticlePDF–3.2M
3.
The Smc5/6 complex is a DNA loop-extruding motor
Biswajit Pradhan, Takaharu Kanno, Miki Umeda Igarashi, Mun Siong Loke, Martin Dieter Baaske, Jan Siu Kei Wong, Kristian Jeppsson, Camilla Björkegren, Eugene Kim
Nature. 2023; 616(7958): 843–848. Published online 2023 Apr 19. doi: 10.1038/s41586-023-05963-3
PMCID:
PMC10132971
AbstractArticlePDF–5.8M
4.
New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry
Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224
PMCID:
PMC9209811
AbstractArticlePDF–818K
5.
Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes
You Yu, Shibai Li, Zheng Ser, Huihui Kuang, Thane Than, Danying Guan, Xiaolan Zhao, Dinshaw J. Patel
Proc Natl Acad Sci U S A. 2022 Jun 7; 119(23): e2202799119. Published online 2022 Jun 1. doi: 10.1073/pnas.2202799119
PMCID:
PMC9191643
AbstractArticlePDF–4.1M
6.
Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs
Nathalia Varejão, Jara Lascorz, Joan Codina-Fabra, Gemma Bellí, Helena Borràs-Gas, Jordi Torres-Rosell, David Reverter
Nat Commun. 2021; 12: 7013. Published online 2021 Dec 1. doi: 10.1038/s41467-021-27301-9
PMCID:
PMC8636563
AbstractArticlePDF–3.6M
7.
Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding
Michael Taschner, Jérôme Basquin, Barbara Steigenberger, Ingmar B Schäfer, Young‐Min Soh, Claire Basquin, Esben Lorentzen, Markus Räschle, Richard A Scheltema, Stephan Gruber
EMBO J. 2021 Aug 2; 40(15): e107807. Published online 2021 Jun 30. doi: 10.15252/embj.2021107807
PMCID:
PMC8327961
AbstractArticlePDF–5.6M
8.
Integrative analysis reveals unique structural and functional features of the Smc5/6 complex
You Yu, Shibai Li, Zheng Ser, Tanmoy Sanyal, Koyi Choi, Bingbing Wan, Huihui Kuang, Andrej Sali, Alex Kentsis, Dinshaw J. Patel, Xiaolan Zhao
Proc Natl Acad Sci U S A. 2021 May 11; 118(19): e2026844118. Published online 2021 May 3. doi: 10.1073/pnas.2026844118
PMCID:
PMC8126833
AbstractArticlePDF–2.3M
9.
Nse5/6 is a negative regulator of the ATPase activity of the Smc5/6 complex
Stephen T Hallett, Pascale Schellenberger, Lihong Zhou, Fabienne Beuron, Ed Morris, Johanne M Murray, Antony W Oliver
Nucleic Acids Res. 2021 May 7; 49(8): 4534–4549. Published online 2021 Apr 13. doi: 10.1093/nar/gkab234
PMCID:
PMC8096239
AbstractArticlePDF–5.3M
10.
Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction
Pilar Gutierrez-Escribano, Silvia Hormeño, Julene Madariaga-Marcos, Roger Solé-Soler, Francis J. O’Reilly, Kyle Morris, Clara Aicart-Ramos, Ricardo Aramayo, Alex Montoya, Holger Kramer, Juri Rappsilber, Jordi Torres-Rosell, Fernando Moreno-Herrero, Luis Aragon
Mol Cell. 2020 Dec 17; 80(6): 1039–1054.e6. doi: 10.1016/j.molcel.2020.11.012
PMCID:
PMC7758880
AbstractArticle
11.
Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1
Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman
G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709
PMCID:
PMC7718751
AbstractArticlePDF–1.2M
12.
Systematic Analysis of Complex Genetic Interactions
Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers
Science. Author manuscript; available in PMC 2018 Nov 4.
Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729
PMCID:
PMC6215713
AbstractArticlePDF–1.9M
13.
Acute Smc5/6 depletion reveals its primary role in rDNA replication by restraining recombination at fork pausing sites
Xiao P. Peng, Shelly Lim, Shibai Li, Lisette Marjavaara, Andrei Chabes, Xiaolan Zhao
PLoS Genet. 2018 Jan; 14(1): e1007129. Published online 2018 Jan 23. doi: 10.1371/journal.pgen.1007129
PMCID:
PMC5779651
AbstractArticlePDF–5.3M
14.
A global interaction network maps a wiring diagram of cellular function
Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone
Science. Author manuscript; available in PMC 2017 Oct 30.
Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420
PMCID:
PMC5661885
AbstractArticlePDF–2.6M
15.
Incision of damaged DNA in the presence of an impaired Smc5/6 complex imperils genome stability
Jie Peng, Wenyi Feng
Nucleic Acids Res. 2016 Dec 1; 44(21): 10216–10229. Published online 2016 Aug 17. doi: 10.1093/nar/gkw720
PMCID:
PMC5137426
AbstractArticlePDF–6.6M
16.
Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates
Jacob N. Bonner, Koyi Choi, Xiaoyu Xue, Nikko P. Torres, Barnabas Szakal, Lei Wei, Bingbing Wan, Meret Arter, Joao Matos, Patrick Sung, Grant W. Brown, Dana Branzei, Xiaolan Zhao
Cell Rep. Author manuscript; available in PMC 2017 Jul 12.
Published in final edited form as: Cell Rep. 2016 Jul 12; 16(2): 368–378. Published online 2016 Jun 30. doi: 10.1016/j.celrep.2016.06.015
PMCID:
PMC5051638
AbstractArticlePDF–805K
17.
Non-Smc element 5 (Nse5) of the Smc5/6 complex interacts with SUMO pathway components
Denise E. Bustard, Lindsay G. Ball, Jennifer A. Cobb
Biol Open. 2016 Jun 15; 5(6): 777–785. Published online 2016 May 23. doi: 10.1242/bio.018440
PMCID:
PMC4920195
AbstractArticlePDF–2.2M
18.
An inter‐species protein–protein interaction network across vast evolutionary distance
Quan Zhong, Samuel J Pevzner, Tong Hao, Yang Wang, Roberto Mosca, Jörg Menche, Mikko Taipale, Murat Taşan, Changyu Fan, Xinping Yang, Patrick Haley, Ryan R Murray, Flora Mer, Fana Gebreab, Stanley Tam, Andrew MacWilliams, Amélie Dricot, Patrick Reichert, Balaji Santhanam, Lila Ghamsari, Michael A Calderwood, Thomas Rolland, Benoit Charloteaux, Susan Lindquist, Albert‐László Barabási, David E Hill, Patrick Aloy, Michael E Cusick, Yu Xia, Frederick P Roth, Marc Vidal
Mol Syst Biol. 2016 Apr; 12(4): 865. Published online 2016 Apr 23. doi: 10.15252/msb.20156484
PMCID:
PMC4848758
AbstractArticlePDF–2.1M
19.
PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL
Chihiro Horigome, Denise E. Bustard, Isabella Marcomini, Neda Delgoshaie, Monika Tsai-Pflugfelder, Jennifer A. Cobb, Susan M. Gasser
Genes Dev. 2016 Apr 15; 30(8): 931–945. doi: 10.1101/gad.277665.116
PMCID:
PMC4840299
AbstractArticlePDF–1.4M
20.
Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance
Demis Menolfi, Axel Delamarre, Armelle Lengronne, Philippe Pasero, Dana Branzei
Mol Cell. 2015 Dec 17; 60(6): 835–846. doi: 10.1016/j.molcel.2015.10.023
PMCID:
PMC4691243
AbstractArticle

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