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Select item 111260511.

The Disassociation of A3G-Related HIV-1 cDNA G-to-A Hypermutation to Viral Infectivity

Joanie Martin, Xin Chen, Xiangxu Jia, Qiujia Shao, Bindong Liu

Viruses. 2024 May; 16(5): 728. Published online 2024 May 4. doi: 10.3390/v16050728

PMCID:: PMC11126051

Abstract Article PDF–2.6M

Select item 108218342.

HIV-1 Vif protein sequence variations in South African people living with HIV and their influence on Vif-APOBEC3G interaction

Monray Edward Williams

Eur J Clin Microbiol Infect Dis. 2024; 43(2): 325–338. Published online 2023 Dec 11. doi: 10.1007/s10096-023-04728-0

PMCID:: PMC10821834

Abstract Article PDF–3.5M

Select item 107258773.

Regulatory variants of APOBEC3 genes potentially associate with COVID-19 severity in populations with African ancestry

Ke Zhang, Fang Chen, Hu-Yan Shen, Ping-Ping Zhang, Han Gao, Hong Peng, Yu-Si Luo, Zhong-Shan Cheng

Sci Rep. 2023; 13: 22435. Published online 2023 Dec 17. doi: 10.1038/s41598-023-49791-x

PMCID:: PMC10725877

Abstract Article PDF–4.6M

Select item 107064654.

APOBEC3G Is a p53-Dependent Restriction Factor in Respiratory Syncytial Virus Infection of Human Cells Included in the p53/Immune Axis

Wesley Gladwell, Oriana Yost, Heather Li, Whitney J. Bell, Shih-Heng Chen, James M. Ward, Steven R. Kleeberger, Michael A. Resnick, Daniel Menendez

Int J Mol Sci. 2023 Dec; 24(23): 16793. Published online 2023 Nov 27. doi: 10.3390/ijms242316793

PMCID:: PMC10706465

Abstract Article PDF–2.7M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101459276.

Keratinocytes sense and eliminate CRISPR DNA through STING/IFN-κ activation and APOBEC3G induction

Mrinal K. Sarkar, Ranjitha Uppala, Chang Zeng, Allison C. Billi, Lam C. Tsoi, Austin Kidder, Xianying Xing, Bethany E. Perez White, Shuai Shao, Olesya Plazyo, Sirisha Sirobhushanam, Enze Xing, Yanyun Jiang, Katherine A. Gallagher, John J. Voorhees, J. Michelle Kahlenberg, Johann E. Gudjonsson

J Clin Invest. 2023 May 1; 133(9): e159393. Published online 2023 May 1. doi: 10.1172/JCI159393

PMCID:: PMC10145927

Abstract Article PDF–6.1M

Select item 100795697.

APOBEC3G protects the genome of human cultured cells and mice from radiation-induced damage

Yelena Britan-Rosich, Jing Ma, Eran Kotler, Faizan Hassan, Alexander Botvinnik, Yoav Smith, Ofra Moshel, Abed Nasereddin, Gunjan Sharma, Eli Pikarsky, Susan Ross, Moshe Kotler

FEBS J. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: FEBS J. 2023 Apr; 290(7): 1822–1839. Published online 2022 Nov 25. doi: 10.1111/febs.16673

PMCID:: PMC10079569

Abstract Article PDF–2.0M

Select item 100334108.

The structural basis for HIV-1 Vif antagonism of human APOBEC3G

Yen-Li Li, Caroline A. Langley, Caleigh M. Azumaya, Ignacia Echeverria, Nicholas M. Chesarino, Michael Emerman, Yifan Cheng, John D. Gross

Nature. 2023; 615(7953): 728–733. Published online 2023 Feb 8. doi: 10.1038/s41586-023-05779-1

PMCID:: PMC10033410

Abstract Article PDF–46M

Select item 99452509.

Deubiquitinase ubiquitin-specific protease 3 (USP3) inhibits HIV-1 replication via promoting APOBEC3G (A3G) expression in both enzyme activity-dependent and -independent manners

Simin Zhao, Baisong Zheng, Liuli Wang, Wenzhe Cui, Chunlai Jiang, Zhuo Li, Wenying Gao, Wenyan Zhang

Chin Med J (Engl) 2022 Nov 20; 135(22): 2706–2717. Published online 2022 Dec 27. doi: 10.1097/CM9.0000000000002478

PMCID:: PMC9945250

Abstract Article PDF–2.9M

Select item 981238110.

Structural basis for HIV-1 antagonism of host APOBEC3G via Cullin E3 ligase

Fumiaki Ito, Ana L. Alvarez-Cabrera, Shiheng Liu, Hanjing Yang, Anna Shiriaeva, Z. Hong Zhou, Xiaojiang S. Chen

Sci Adv. 2023 Jan; 9(1): eade3168. Published online 2023 Jan 4. doi: 10.1126/sciadv.ade3168

PMCID:: PMC9812381

Abstract Article PDF–1.3M

Select item 950354011.

The Identification of APOBEC3G as a Potential Prognostic Biomarker in Acute Myeloid Leukemia and a Possible Drug Target for Crotonoside

Chenchen Ma, Peng Liu, Siyuan Cui, Chang Gao, Xing Tan, Zhaopeng Liu, Ruirong Xu

Molecules. 2022 Sep; 27(18): 5804. Published online 2022 Sep 7. doi: 10.3390/molecules27185804

PMCID:: PMC9503540

Abstract Article PDF–3.2M

Select item 947067912.

The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness

Kyumin Kim, Peter Calabrese, Shanshan Wang, Chao Qin, Youliang Rao, Pinghui Feng, Xiaojiang S. Chen

Sci Rep. 2022; 12: 14972. Published online 2022 Sep 13. doi: 10.1038/s41598-022-19067-x

PMCID:: PMC9470679

Abstract Article PDF–5.8M

Select item 914914013.

HIV-1 VIF and human APOBEC3G interaction directly observed through molecular specific labeling using a new dual promotor vector

Wazo Myint, Celia A. Schiffer, Hiroshi Matsuo

J Magn Reson. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: J Magn Reson. 2022 Jun; 339: 107230. Published online 2022 Apr 26. doi: 10.1016/j.jmr.2022.107230

PMCID:: PMC9149140

Abstract Article PDF–1.3M

Select item 879130014.

Host Restriction Factor A3G Inhibits the Replication of Enterovirus D68 by Competitively Binding the 5′ Untranslated Region with PCBP1

Zhaolong Li, Xu Yang, Zhilei Zhao, Xin Liu, Wenyan Zhang

J Virol. 2022 Jan; 96(2): e01708-21. Prepublished online 2021 Nov 3. Published online 2022 Jan 26. doi: 10.1128/JVI.01708-21

PMCID:: PMC8791300

Abstract Article PDF–4.0M

Select item 875251415.

Differential activity of APOBEC3F, APOBEC3G, and APOBEC3H in the restriction of HIV-2

Morgan E. Meissner, Nora A. Willkomm, Jamie Lucas, William G. Arndt, Sarah F. Aitken, Emily J. Julik, Sunanda Baliga, Louis M. Mansky

J Mol Biol. Author manuscript; available in PMC 2023 Jan 30.

Published in final edited form as: J Mol Biol. 2022 Jan 30; 434(2): 167355. Published online 2021 Nov 10. doi: 10.1016/j.jmb.2021.167355

PMCID:: PMC8752514

Abstract Article PDF–883K

Select item 850103516.

Dysregulated APOBEC3G causes DNA damage and promotes genomic instability in multiple myeloma

Srikanth Talluri, Mehmet K. Samur, Leutz Buon, Subodh Kumar, Lakshmi B. Potluri, Jialan Shi, Rao H. Prabhala, Masood A. Shammas, Nikhil C. Munshi

Blood Cancer J. 2021 Oct; 11(10): 166. Published online 2021 Oct 8. doi: 10.1038/s41408-021-00554-9

PMCID:: PMC8501035

Abstract Article PDF–2.6M

Select item 846044717.

CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation

Sebastian Kostrhon, J. Rajan Prabu, Kheewoong Baek, Daniel Horn-Ghetko, Susanne von Gronau, Maren Klügel, Jérôme Basquin, Arno F. Alpi, Brenda A. Schulman

Nat Chem Biol. 2021; 17(10): 1075–1083. Published online 2021 Sep 13. doi: 10.1038/s41589-021-00858-8

PMCID:: PMC8460447

Abstract Article PDF–13M

Select item 844035718.

The von Hippel–Lindau Cullin-RING E3 ubiquitin ligase regulates APOBEC3 cytidine deaminases

Gaël K. Scholtès, Aubrey M. Sawyer, Cristina C. Vaca, Isabelle Clerc, Meejeon Roh, Chisu Song, Richard T. D’Aquila

Transl Res. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: Transl Res. 2021 Nov; 237: 1–15. Published online 2021 May 15. doi: 10.1016/j.trsl.2021.05.002

PMCID:: PMC8440357

Abstract Article PDF–628K

Select item 826661719.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

Select item 777106820.

Crystal structure of a soluble APOBEC3G variant suggests ssDNA to bind in a channel that extends between the two domains.

Atanu Maiti, Wazo Myint, Krista A. Delviks-Frankenberry, Shurong Hou, Tapan Kanai, Vanivilasini Balachandran, Christina Sierra Rodriguez, Rashmi Tripathi, Nese Kurt Yilmaz, Vinay K. Pathak, Celia A. Schiffer, Hiroshi Matsuo

J Mol Biol. Author manuscript; available in PMC 2021 Nov 20.

Published in final edited form as: J Mol Biol. 2020 Nov 20; 432(23): 6042–6060. Published online 2020 Oct 22. doi: 10.1016/j.jmb.2020.10.020