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Select item 106949071.

Fructose-bisphosphatase1 (FBP1) alleviates experimental osteoarthritis by regulating Protein crumbs homolog 3 (CRB3)

Zhuolun Wang, Xinjie Wang, Liangliang Liu, Xiongtian Guo, Haiyan Zhang, Jianbing Yin, Rengui Lin, Yan Shao, Daozhang Cai

Arthritis Res Ther. 2023; 25: 235. Published online 2023 Dec 4. doi: 10.1186/s13075-023-03221-5

Correction in:: Arthritis Res Ther. 2023; 25: 250.

PMCID:: PMC10694907

Abstract Article PDF–7.1M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81063083.

Aberrant epithelial polarity cues drive the development of precancerous airway lesions

Andrew Tilston-Lunel, Sarah Mazzilli, Nathan M. Kingston, Aleksander D. Szymaniak, Julia Hicks-Berthet, Joseph G. Kern, Kristine Abo, Mary E. Reid, Catalina Perdomo, Andrew A. Wilson, Avrum Spira, Jennifer Beane, Xaralabos Varelas

Proc Natl Acad Sci U S A. 2021 May 4; 118(18): e2019282118. Published online 2021 Apr 26. doi: 10.1073/pnas.2019282118

PMCID:: PMC8106308

Abstract Article PDF–2.8M

Select item 71699834.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 68032885.

A CRISPR Screen Identifies the Cell Polarity Determinant Crumbs 3 as an Adeno-associated Virus Restriction Factor in Hepatocytes

Victoria J. Madigan, Tyne O. Tyson, Julianne A. Yuziuk, Minakshi Pillai, Sven Moller-Tank, Aravind Asokan

J Virol. 2019 Nov 1; 93(21): e00943-19. Prepublished online 2019 Aug 7. Published online 2019 Oct 15. doi: 10.1128/JVI.00943-19

PMCID:: PMC6803288

Abstract Article PDF–3.2M

Select item 67720536.

Crumbs protein homolog 3 (CRB3) expression is associated with oestrogen and progesterone receptor positivity in breast cancer

Pingping Li, Can Zhou, Yu Yan, Juan Li, Jie Liu, Yan Zhang, Peijun Liu

Clin Exp Pharmacol Physiol. 2019 Sep; 46(9): 837–844. Published online 2019 Jun 10. doi: 10.1111/1440-1681.13104

PMCID:: PMC6772053

Abstract Article PDF–1.1M

Select item 67668937.

Crumbs3 is a critical factor that regulates invasion and metastasis of colon adenocarcinoma via the specific interaction with FGFR1

Hidekazu Iioka, Ken Saito, Masakiyo Sakaguchi, Taro Tachibana, Keiichi Homma, Eisaku Kondo

Int J Cancer. 2019 Nov 15; 145(10): 2740–2753. Published online 2019 Apr 29. doi: 10.1002/ijc.32336

PMCID:: PMC6766893

Abstract Article PDF–3.6M

Select item 67137368.

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins

Sascha E. Dho, Nancy Silva-Gagliardi, Fabio Morgese, Etienne Coyaud, Emily Lamoureux, Donna M. Berry, Brian Raught, C. Jane McGlade

Sci Rep. 2019; 9: 12471. Published online 2019 Aug 28. doi: 10.1038/s41598-019-48902-x

PMCID:: PMC6713736

Abstract Article PDF–5.6M

Select item 62373949.

CRB3 and the FERM protein EPB41L4B regulate proliferation of mammary epithelial cells through the release of amphiregulin

Stephanie J. Walker, Laura M. Selfors, Ben L. Margolis, Joan S. Brugge

PLoS One. 2018; 13(11): e0207470. Published online 2018 Nov 15. doi: 10.1371/journal.pone.0207470

PMCID:: PMC6237394

Abstract Article PDF–3.8M

Select item 601081310.

Elevated CRB3 expression suppresses breast cancer stemness by inhibiting β‐catenin signalling to restore tamoxifen sensitivity

Pingping Li, Chen Feng, He Chen, Yina Jiang, Fang Cao, Jie Liu, Peijun Liu

J Cell Mol Med. 2018 Jul; 22(7): 3423–3433. Published online 2018 Mar 30. doi: 10.1111/jcmm.13619

PMCID:: PMC6010813

Abstract Article PDF–3.8M

Select item 538638111.

CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells

Xiaona Mao, Pingping Li, Yaochun Wang, Zheyong Liang, Jie Liu, Juan Li, Yina Jiang, Gang Bao, Lei Li, Bofeng Zhu, Yu Ren, Xinhan Zhao, Jianmin Zhang, Yu Liu, Jin Yang, Peijun Liu

Cell Death Dis. 2017 Jan; 8(1): e2546. Published online 2017 Jan 12. doi: 10.1038/cddis.2016.478

PMCID:: PMC5386381

Abstract Article PDF–5.7M

Select item 456173612.

CRB3A Controls the Morphology and Cohesion of Cancer Cells through Ehm2/p114RhoGEF-Dependent Signaling

Elise Loie, Lucie E. Charrier, Kévin Sollier, Jean-Yves Masson, Patrick Laprise

Mol Cell Biol. 2015 Oct; 35(19): 3423–3435. Prepublished online 2015 Jul 27. Published online 2015 Sep 4. doi: 10.1128/MCB.00673-15

PMCID:: PMC4561736

Abstract Article PDF–3.0M

Select item 426658813.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 358782814.

The WD40 protein Morg1 facilitates Par6–aPKC binding to Crb3 for apical identity in epithelial cells

Junya Hayase, Sachiko Kamakura, Yuko Iwakiri, Yoshihiro Yamaguchi, Tomoko Izaki, Takashi Ito, Hideki Sumimoto

J Cell Biol. 2013 Mar 4; 200(5): 635–650. doi: 10.1083/jcb.201208150

PMCID:: PMC3587828

Abstract Article PDF–5.0M

Select item 298209115.

The SARS Coronavirus E Protein Interacts with PALS1 and Alters Tight Junction Formation and Epithelial Morphogenesis

Kim-Tat Teoh, Yu-Lam Siu, Wing-Lim Chan, Marc A. Schlüter, Chia-Jen Liu, J. S. Malik Peiris, Roberto Bruzzone, Benjamin Margolis, Béatrice Nal

Mol Biol Cell. 2010 Nov 15; 21(22): 3838–3852. doi: 10.1091/mbc.E10-04-0338

PMCID:: PMC2982091

Abstract Article

Select item 263705016.

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper

J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406

PMCID:: PMC2637050

Abstract Article

Select item 206485117.

A novel Crumbs3 isoform regulates cell division and ciliogenesis via importin β interactions

Shuling Fan, Vanessa Fogg, Qian Wang, Xiao-Wei Chen, Chia-Jen Liu, Ben Margolis

J Cell Biol. 2007 Jul 30; 178(3): 387–398. doi: 10.1083/jcb.200609096

PMCID:: PMC2064851

Abstract Article PDF–5.8M

Select item 185502218.

The MAGUK Protein MPP7 Binds to the Polarity Protein hDlg1 and Facilitates Epithelial Tight Junction Formation

Volker M. Stucke, Evy Timmerman, Joel Vandekerckhove, Kris Gevaert, Alan Hall

Mol Biol Cell. 2007 May; 18(5): 1744–1755. doi: 10.1091/mbc.E06-11-0980

PMCID:: PMC1855022

Abstract Article PDF–1.6M

Select item 135612919.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 52892820.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

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