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Select item 100767391.

Genetic deletion of HVEM in a leukemia B cell line promotes a preferential increase of PD-1^- stem cell-like T cells over PD-1⁺ T cells curbing tumor progression

Maria-Luisa del Rio, Carla Yago-Diez de Juan, Giovanna Roncador, Eduardo Caleiras, Ramón Álvarez-Esteban, José Antonio Pérez-Simón, Jose-Ignacio Rodriguez-Barbosa

Front Immunol. 2023; 14: 1113858. Published online 2023 Mar 23. doi: 10.3389/fimmu.2023.1113858

PMCID:: PMC10076739

Abstract Article PDF–7.8M

Select item 97774282.

Tumor Cell-Intrinsic BTLA Receptor Inhibits the Proliferation of Tumor Cells via ERK1/2

Tian-You Cheng, Ya-Juan Liu, Hong Yan, Yi-Bo Xi, Li-Qiang Duan, Yang Wang, Tian-Tian Zhang, Yin-Min Gu, Xiao-Dong Wang, Chang-Xin Wu, Shan Gao

Cells. 2022 Dec; 11(24): 4021. Published online 2022 Dec 12. doi: 10.3390/cells11244021

PMCID:: PMC9777428

Abstract Article PDF–22M

Select item 94468823.

BTLA inhibition has a dominant role in the cis-complex of BTLA and HVEM

Claire Battin, Judith Leitner, Petra Waidhofer-Söllner, Katharina Grabmeier-Pfistershammer, Daniel Olive, Peter Steinberger

Front Immunol. 2022; 13: 956694. Published online 2022 Aug 23. doi: 10.3389/fimmu.2022.956694

PMCID:: PMC9446882

Abstract Article PDF–17M

Select item 86796744.

Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype

Ruben A.L. de Groen, Ronald van Eijk, Stefan Böhringer, Tom van Wezel, Richard Raghoo, Dina Ruano, Patty M. Jansen, Inge Briaire-de Bruijn, Fleur A. de Groot, Karin Kleiverda, Liane te Boome, Valeska Terpstra, Henriette Levenga, Alina Nicolae, Eduardus F.M. Posthuma, Isabelle Focke-Snieders, Lizan Hardi, Wietske C.E. den Hartog, Lara H. Bohmer, Pancras C.W. Hogendoorn, Anke van den Berg, Arjan Diepstra, Marcel Nijland, Pieternella J. Lugtenburg, Marie José Kersten, Steven T. Pals, Hendrik Veelken, Judith V.M.G. Bovée, Arjen H.G. Cleven, Joost S.P. Vermaat

Blood Adv. 2021 Oct 12; 5(19): 3760–3775. Prepublished online 2021 Sep 3. Published online 2021 Oct 1. doi: 10.1182/bloodadvances.2021005215

PMCID:: PMC8679674

Abstract Article PDF–3.1M

Select item 85588385.

HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160

Weifeng Liu, Ting-Fang Chou, Sarah C. Garrett-Thomson, Goo-Young Seo, Elena Fedorov, Udupi A. Ramagopal, Jeffrey B. Bonanno, Qingyang Wang, Kenneth Kim, Scott J. Garforth, Kiyokazu Kakugawa, Hilde Cheroutre, Mitchell Kronenberg, Steven C. Almo

J Exp Med. 2021 Dec 6; 218(12): e20211112. Published online 2021 Oct 28. doi: 10.1084/jem.20211112

PMCID:: PMC8558838

Abstract Article PDF–7.0M

Select item 80459326.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 78386977.

Knockdown of HVEM, a Lymphocyte Regulator Gene, in Ovarian Cancer Cells Increases Sensitivity to Activated T Cells

Ting Zhang, Lei Ye, Lingfei Han, Qizhi He, Jianlong Zhu

Oncol Res. 2016; 24(3): 189–196. Published online 2016 Jul 18. doi: 10.3727/096504016X14641336229602

Correction in:: Oncol Res. 2017; 25(9): 1665.

PMCID:: PMC7838697

Abstract Article PDF–4.9M

Select item 77006518.

Fragments of gD Protein as Inhibitors of BTLA/HVEM Complex Formation - Design, Synthesis, and Cellular Studies

Katarzyna Kuncewicz, Claire Battin, Adam Sieradzan, Agnieszka Karczyńska, Marta Orlikowska, Anna Wardowska, Michał Pikuła, Peter Steinberger, Sylwia Rodziewicz-Motowidło, Marta Spodzieja

Int J Mol Sci. 2020 Nov; 21(22): 8876. Published online 2020 Nov 23. doi: 10.3390/ijms21228876

PMCID:: PMC7700651

Abstract Article PDF–4.4M

Select item 76420939.

Redesigning HVEM interface for selective binding to LIGHT, BTLA, and CD160

Rojan Shrestha, Sarah Garrett-Thomson, Weifeng Liu, Steven C. Almo, Andras Fiser

Structure. Author manuscript; available in PMC 2021 Nov 3.

Published in final edited form as: Structure. 2020 Nov 3; 28(11): 1197–1205.e2. Published online 2020 Aug 13. doi: 10.1016/j.str.2020.07.013

PMCID:: PMC7642093

Abstract Article PDF–1.9M

Select item 732206710.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 724302111.

The Analysis of PTPN6 for Bladder Cancer: An Exploratory Study Based on TCGA

Chengquan Shen, Jing Liu, Jirong Wang, Xiaokun Yang, Haitao Niu, Yonghua Wang

Dis Markers. 2020; 2020: 4312629. Published online 2020 May 13. doi: 10.1155/2020/4312629

PMCID:: PMC7243021

Abstract Article PDF–1.8M

Select item 716897912.

HVEM/HIF-1α promoted proliferation and inhibited apoptosis of ovarian cancer cells under hypoxic microenvironment conditions

Liyan Duan, Jie Tao, Xiaoqian Yang, Lei Ye, Yueqian Wu, Qizhi He, Yingchun Duan, Li Chen, Jianlong Zhu

J Ovarian Res. 2020; 13: 40. Published online 2020 Apr 20. doi: 10.1186/s13048-020-00646-3

PMCID:: PMC7168979

Abstract Article PDF–2.2M

Select item 690044713.

Herpes Virus Entry Mediator(HVEM): A novel potential mediator of trauma induced immunosuppression

Michelle E. Wakeley, Nicholas J Shubin, Sean F. Monaghan, Chyna C. Gray, Alfred Ayala, Daithi S. Heffernan

J Surg Res. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: J Surg Res. 2020 Jan; 245: 610–618. Published online 2019 Sep 12. doi: 10.1016/j.jss.2019.07.009

PMCID:: PMC6900447

Abstract Article PDF–1.5M

Select item 655778514.

Immune checkpoint molecule herpes virus entry mediator is overexpressed and associated with poor prognosis in human glioblastoma

Ming-Zhi Han, Shuai Wang, Wen-Bo Zhao, Shi-Lei Ni, Ning Yang, Yang Kong, Bin Huang, An-Jing Chen, Xin-Gang Li, Jian Wang, Dong-Hai Wang

EBioMedicine. 2019 May; 43: 159–170. Published online 2019 Apr 12. doi: 10.1016/j.ebiom.2019.04.002

PMCID:: PMC6557785

Abstract Article PDF–7.6M

Select item 652814015.

High TNFRSF14 and low BTLA are associated with poor prognosis in Follicular Lymphoma and in Diffuse Large B-cell Lymphoma transformation

Joaquim Carreras, Armando Lopez-Guillermo, Yara Yukie Kikuti, Johbu Itoh, Miyaoka Masashi, Haruka Ikoma, Sakura Tomita, Shinichiro Hiraiwa, Rifat Hamoudi, Andreas Rosenwald, Ellen Leich, Antonio Martinez, Giovanna Roncador, Neus Villamor, Lluis Colomo, Patricia Perez, Noriko M Tsuji, Elias Campo, Naoya Nakamura

J Clin Exp Hematop. 2019 Mar; 59(1): 1–16. Published online 2019 Mar 27. doi: 10.3960/jslrt.19003

PMCID:: PMC6528140

Abstract Article PDF–4.0M

Select item 648550716.

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

Iain C. Macaulay, Marloes R. Tijssen, Daphne C. Thijssen-Timmer, Arief Gusnanto, Michael Steward, Philippa Burns, Cordelia F. Langford, Peter D. Ellis, Frank Dudbridge, Jaap-Jan Zwaginga, Nicholas A. Watkins, C. Ellen van der Schoot, Willem H. Ouwehand

Blood. Author manuscript; available in PMC 2019 Apr 26.

Published in final edited form as: Blood. 2007 Apr 15; 109(8): 3260–3269. Published online 2006 Dec 27. doi: 10.1182/blood-2006-07-036269