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Select item 114413291.

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels

Morven Chin, Pascal S. Kaeser

Cell Rep. Author manuscript; available in PMC 2024 Sep 30.

Published in final edited form as: Cell Rep. 2024 Jul 23; 43(7): 114428. Published online 2024 Jul 11. doi: 10.1016/j.celrep.2024.114428

PMCID:: PMC11441329

Abstract Article PDF–2.3M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107693503.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 107157274.

Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6

Anna A Cook, Tsz Chui Sophia Leung, Max Rice, Maya Nachman, Élyse Zadigue-Dube, Alanna Jean Watt

eLife. 2023; 12: RP90510. Published online 2023 Dec 12. doi: 10.7554/eLife.90510

PMCID:: PMC10715727

Abstract Article PDF–5.9M

Select item 106237245.

Chronic pregabalin treatment protects against spreading depolarization and alters hippocampal synaptic characteristics in a model of familial hemiplegic migraine-type 1

Stuart M. Cain, Sascha R. A. Alles, Ray Gopaul, Louis-Philippe Bernier, Andrew C. Yung, Andrew Bauman, Yi Yang, Glen B. Baker, Piotr Kozlowski, Brian A. MacVicar, Terrance P. Snutch

Mol Brain. 2023; 16: 76. Published online 2023 Nov 3. doi: 10.1186/s13041-023-01062-6

PMCID:: PMC10623724

Abstract Article PDF–3.0M

Select item 103078526.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 103077157.

The Transcription Factor, α1ACT, Acts Through a MicroRNA Network to Regulate Neurogenesis and Cell Death During Neonatal Cerebellar Development

Cenfu Wei, Kellie Benzow, Michael D. Koob, Christopher M. Gomez, Xiaofei Du

Cerebellum. 2023; 22(4): 651–662. Published online 2022 Jun 22. doi: 10.1007/s12311-022-01431-2

Correction in:: Cerebellum. 2024; 23(2): 876.

PMCID:: PMC10307715

Abstract Article PDF–4.1M

Select item 102917528.

Identification and characterization of transcribed enhancers during cerebellar development through enhancer RNA analysis

Miguel Ramirez, Remi Robert, Joanna Yeung, Joshua Wu, Ayasha Abdalla-Wyse, FANTOM 5 Consortium, Daniel Goldowitz

BMC Genomics. 2023; 24: 351. Published online 2023 Jun 26. doi: 10.1186/s12864-023-09368-4

PMCID:: PMC10291752

Abstract Article PDF–4.9M

Select item 102585569.

Cerebellar granule cell signaling is indispensable for normal motor performance

Joon-Hyuk Lee, Mehak M. Khan, Amanda P. Stark, Soobin Seo, Aliya Norton, Zhiyi Yao, Christopher H. Chen, Wade G. Regehr

Cell Rep. Author manuscript; available in PMC 2023 Jun 12.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112429. Published online 2023 May 3. doi: 10.1016/j.celrep.2023.112429

PMCID:: PMC10258556

Abstract Article PDF–3.0M

Select item 945474510.

Loss of Flocculus Purkinje Cell Firing Precision Leads to Impaired Gaze Stabilization in a Mouse Model of Spinocerebellar Ataxia Type 6 (SCA6)

Hui Ho Vanessa Chang, Anna A. Cook, Alanna J. Watt, Kathleen E. Cullen

Cells. 2022 Sep; 11(17): 2739. Published online 2022 Sep 2. doi: 10.3390/cells11172739

PMCID:: PMC9454745

Abstract Article PDF–2.3M

Select item 941075911.

Deletion of the P/Q-Type Calcium Channel from Serotonergic Neurons Drives Male Aggression in Mice

Pauline Bohne, Achim Volkmann, Martin K. Schwarz, Melanie D. Mark

J Neurosci. 2022 Aug 24; 42(34): 6637–6653. doi: 10.1523/JNEUROSCI.0204-22.2022

PMCID:: PMC9410759

Abstract Article PDF–8.8M

Select item 941075112.

Enhanced Feedback Inhibition Due to Increased Recruitment of Somatostatin-Expressing Interneurons and Enhanced Cortical Recurrent Excitation in a Genetic Mouse Model of Migraine

Ivan Marchionni, Nadia Pilati, Angelo Forli, Michele Sessolo, Angelita Tottene, Daniela Pietrobon

J Neurosci. 2022 Aug 24; 42(34): 6654–6666. doi: 10.1523/JNEUROSCI.0228-22.2022

PMCID:: PMC9410751

Abstract Article PDF–2.1M

Select item 916307713.

Complex effects on Ca_V2.1 channel gating caused by a CACNA1A variant associated with a severe neurodevelopmental disorder

Benjamin J. Grosso, Audra A. Kramer, Sidharth Tyagi, Daniel F. Bennett, Cynthia J. Tifft, Precilla D’Souza, Michael F. Wangler, Ellen F. Macnamara, Ulises Meza, Roger A. Bannister

Sci Rep. 2022; 12: 9186. Published online 2022 Jun 2. doi: 10.1038/s41598-022-12789-y

PMCID:: PMC9163077

Abstract Article PDF–3.3M

Select item 908198514.

An action potential initiation mechanism in distal axons for the control of dopamine release

Changliang Liu, Xintong Cai, Andreas Ritzau-Jost, Paul F. Kramer, Yulong Li, Zayd M. Khaliq, Stefan Hallermann, Pascal S. Kaeser

Science. Author manuscript; available in PMC 2023 Mar 25.

Published in final edited form as: Science. 2022 Mar 25; 375(6587): 1378–1385. Published online 2022 Mar 24. doi: 10.1126/science.abn0532

PMCID:: PMC9081985

Abstract Article PDF–2.3M

Select item 908118315.

Rebuilding essential active zone functions within a synapse

Chao Tan, Shan Shan H. Wang, Giovanni de Nola, Pascal S. Kaeser

Neuron. Author manuscript; available in PMC 2023 May 4.

Published in final edited form as: Neuron. 2022 May 4; 110(9): 1498–1515.e8. Published online 2022 Feb 16. doi: 10.1016/j.neuron.2022.01.026

PMCID:: PMC9081183

Abstract Article PDF–4.3M

Select item 893433616.

Controlling absence seizures from the cerebellar nuclei via activation of the G_q signaling pathway

Jan Claudius Schwitalla, Johanna Pakusch, Brix Mücher, Alexander Brückner, Dominic Alexej Depke, Thomas Fenzl, Chris I. De Zeeuw, Lieke Kros, Freek E. Hoebeek, Melanie D. Mark

Cell Mol Life Sci. 2022 Apr; 79(4): 197. Published online 2022 Mar 19. doi: 10.1007/s00018-022-04221-5

PMCID:: PMC8934336

Abstract Article PDF–4.2M

Select item 892050417.

Ca_V2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury

Nicole A Terpolilli, Reinhard Dolp, Kai Waehner, Susanne M Schwarzmaier, Elisabeth Rumbler, Boyan Todorov, Michel D Ferrari, Arn MJM van den Maagdenberg, Nikolaus Plesnila

eLife. 2022; 11: e74923. Published online 2022 Mar 3. doi: 10.7554/eLife.74923

PMCID:: PMC8920504

Abstract Article PDF–1.1M

Select item 861097418.

Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation

Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin

Sci Rep. 2021; 11: 22745. Published online 2021 Nov 23. doi: 10.1038/s41598-021-02218-x

PMCID:: PMC8610974

Abstract Article PDF–2.5M

Select item 844444919.

Cognitive deficits in episodic ataxia type 2 mouse models

Pauline Bohne, Damian Boden-El Mourabit, Mareike Josten, Melanie D Mark

Hum Mol Genet. 2021 Oct 1; 30(19): 1811–1832. Published online 2021 Jun 2. doi: 10.1093/hmg/ddab149

PMCID:: PMC8444449

Abstract Article PDF–2.9M

Select item 804413820.

Spreading depression as an innate antiseizure mechanism

Isra Tamim, David Y. Chung, Andreia Lopes de Morais, Inge C. M. Loonen, Tao Qin, Amrit Misra, Frieder Schlunk, Matthias Endres, Steven J. Schiff, Cenk Ayata

Nat Commun. 2021; 12: 2206. Published online 2021 Apr 13. doi: 10.1038/s41467-021-22464-x

PMCID:: PMC8044138

Abstract Article PDF–5.1M

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