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Select item 110727401.

DUSP1 interacts with and dephosphorylates VCP to improve mitochondrial quality control against endotoxemia-induced myocardial dysfunction

Hang Zhu, Jin Wang, Ting Xin, Shanshan Chen, Ruiying Hu, Yukun Li, Mingming Zhang, Hao Zhou

Cell Mol Life Sci. 2023 Aug; 80(8): 213. Published online 2023 Jul 18. doi: 10.1007/s00018-023-04863-z

PMCID:: PMC11072740

Abstract Article PDF–16M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108710473.

Hepatocyte-specific mitogen-activated protein kinase phosphatase 1 in sexual dimorphism and susceptibility to alcohol induced liver injury

Mary Nancy Walter, Diego Montoya-Durango, Walter Rodriguez, Yali Wang, JingWen Zhang, Julia H. Chariker, Eric C. Rouchka, Claudio Maldonado, Anton Bennett, Craig James McClain, Shirish Barve, Leila Gobejishvili

Front Immunol. 2024; 15: 1316228. Published online 2024 Feb 1. doi: 10.3389/fimmu.2024.1316228

PMCID:: PMC10871047

Abstract Article PDF–10M

Select item 108480844.

MKP‐1 regulates the inflammatory activation of microglia against Alzheimer's disease

Junhua Li, Lin Wang, Qinhua Zeng, Jing He, Qing Tang, Kejian Wang, Guiqiong He

CNS Neurosci Ther. 2024 Feb; 30(2): e14409. Published online 2023 Aug 21. doi: 10.1111/cns.14409

PMCID:: PMC10848084

Abstract Article PDF–15M

Select item 108452625.

Dual-specificity phosphatase 1 interacts with prohibitin 2 to improve mitochondrial quality control against type-3 cardiorenal syndrome

Nanyang Liu, Yanqiu Ding, Hao Zhou, Xing Chang, Long Lou

Int J Med Sci. 2024; 21(3): 547–561. Published online 2024 Jan 19. doi: 10.7150/ijms.90484

PMCID:: PMC10845262

Abstract Article PDF–8.4M

Select item 106304536.

DUSP1 protects against ischemic acute kidney injury through stabilizing mtDNA via interaction with JNK

Lang Shi, Hongchu Zha, Zhou Pan, Jiayi Wang, Yao Xia, Huimin Li, Hua Huang, Ruchi Yue, Zhixia Song, Jiefu Zhu

Cell Death Dis. 2023 Nov; 14(11): 724. Published online 2023 Nov 7. doi: 10.1038/s41419-023-06247-4

PMCID:: PMC10630453

Abstract Article PDF–11M

Select item 104804997.

MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention

Bin Qiu, Ahmed Lawan, Chrysovalantou E. Xirouchaki, Jae-Sung Yi, Marie Robert, Lei Zhang, Wendy Brown, Carlos Fernández-Hernando, Xiaoyong Yang, Tony Tiganis, Anton M. Bennett

Nat Commun. 2023; 14: 5405. Published online 2023 Sep 5. doi: 10.1038/s41467-023-41145-5

PMCID:: PMC10480499

Abstract Article PDF–6.7M

Select item 102047788.

Inhibition of Mitogen-Activated Protein Kinase Phosphatase-1 (MKP-1) Increases Experimental Stroke Injury

Lin Liu, Sarah Doran, Yan Xu, Bharti Manwani, Rodney Ritzel, Sharon Benashski, Louise McCullough, Jun Li

Exp Neurol. Author manuscript; available in PMC 2023 May 23.

Published in final edited form as: Exp Neurol. 2014 Nov; 261: 404–411. Published online 2014 May 17. doi: 10.1016/j.expneurol.2014.05.009

PMCID:: PMC10204778

Abstract Article PDF–1.5M

Select item 100927559.

Interaction between dual specificity phosphatase-1 and cullin-1 attenuates alcohol-related liver disease by restoring p62-mediated mitophagy

Ruibing Li, Zhe Dai, Xiaoman Liu, Chunling Wang, Jia Huang, Ting Xin, Ying Tong, Yijin Wang

Int J Biol Sci. 2023; 19(6): 1831–1845. Published online 2023 Mar 21. doi: 10.7150/ijbs.81447

PMCID:: PMC10092755

Abstract Article PDF–10M

Select item 1003674010.

The Ninj1/Dusp1 Axis Contributes to Liver Ischemia Reperfusion Injury by Regulating Macrophage Activation and Neutrophil Infiltration

Yuanchang Hu, Feng Zhan, Yong Wang, Dong Wang, Hao Lu, Chen Wu, Yongxiang Xia, Lijuan Meng, Feng Zhang, Xun Wang, Shun Zhou

Cell Mol Gastroenterol Hepatol. 2023; 15(5): 1071–1084. Published online 2023 Jan 31. doi: 10.1016/j.jcmgh.2023.01.008

PMCID:: PMC10036740

Abstract Article PDF–5.7M

Select item 1002516311.

p38 MAPK and MKP-1 control the glycolytic program via the bifunctional glycolysis regulator PFKFB3 during sepsis

Carli E. Mager, Justin M. Mormol, Evan D. Shelton, Parker R. Murphy, Bridget A. Bowman, Timothy J. Barley, Xiantao Wang, Sarah C. Linn, Kevin Liu, Leif D. Nelin, Markus Hafner, Yusen Liu

J Biol Chem. 2023 Apr; 299(4): 103043. Published online 2023 Feb 17. doi: 10.1016/j.jbc.2023.103043

PMCID:: PMC10025163

Abstract Article PDF–2.8M

Select item 1000299812.

MKP-1 Deficiency Exacerbates Skin Fibrosis in a Mouse Model of Scleroderma

Morena Scotece, Mari Hämäläinen, Tiina Leppänen, Katriina Vuolteenaho, Eeva Moilanen

Int J Mol Sci. 2023 Mar; 24(5): 4668. Published online 2023 Feb 28. doi: 10.3390/ijms24054668

PMCID:: PMC10002998

Abstract Article PDF–2.3M

Select item 941898713.

Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolism

Ying Tan, Yue Zhang, Jing He, Feng Wu, Di Wu, Nengxian Shi, Weifeng Liu, Ziying Li, Wenqian Liu, Hao Zhou, Wenting Chen

Mol Metab. 2022 Oct; 64: 101567. Published online 2022 Aug 6. doi: 10.1016/j.molmet.2022.101567

PMCID:: PMC9418987

Abstract Article PDF–3.2M

Select item 910899414.

Mitogen-activated protein kinase phosphatase-1 controls PD-L1 expression by regulating type I interferon during systemic Escherichia coli infection

Timothy J. Barley, Parker R. Murphy, Xiantao Wang, Bridget A. Bowman, Justin M. Mormol, Carli E. Mager, Sean G. Kirk, Charles J. Cash, Sarah C. Linn, Xiaomei Meng, Leif D. Nelin, Bernadette Chen, Markus Hafner, Jian Zhang, Yusen Liu

J Biol Chem. 2022 May; 298(5): 101938. Published online 2022 Apr 13. doi: 10.1016/j.jbc.2022.101938

PMCID:: PMC9108994

Abstract Article PDF–2.9M

Select item 899874015.

Dexamethasone Attenuates the Expression of MMP-13 in Chondrocytes through MKP-1

Tiina Lehtola, Elina Nummenmaa, Lauri Tuure, Mari Hämäläinen, Riina M. Nieminen, Teemu Moilanen, Antti Pemmari, Eeva Moilanen

Int J Mol Sci. 2022 Apr; 23(7): 3880. Published online 2022 Mar 31. doi: 10.3390/ijms23073880

PMCID:: PMC8998740

Abstract Article PDF–916K

Select item 869950916.

The MAP Kinase Phosphatase MKP-1 Modulates Neurogenesis via Effects on BNIP3 and Autophagy

Yinghui Li, Marc W. Halterman

Biomolecules. 2021 Dec; 11(12): 1871. Published online 2021 Dec 14. doi: 10.3390/biom11121871

PMCID:: PMC8699509

Abstract Article PDF–5.2M

Select item 861731117.

MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model

William E. Tidyman, Alice F. Goodwin, Yoshiko Maeda, Ophir D. Klein, Katherine A. Rauen

Dis Model Mech. 2022 Feb 1; 15(2): dmm049166. Published online 2021 Nov 19. doi: 10.1242/dmm.049166

PMCID:: PMC8617311

Abstract Article

Select item 861703618.

Knockout of MAPK phosphatase-1 Exaggerates Type I Interferon Response during Systemic Escherichia coli Infection

Sean G. Kirk, Parker R. Murphy, Xiantao Wang, Charles J. Cash, Timothy J. Barley, Bridget A. Bowman, Abel J. Batty, William E. Ackerman, IV, Jian Zhang, Leif D. Nelin, Markus Hafner, Yusen Liu

J Immunol. Author manuscript; available in PMC 2022 Jun 15.

Published in final edited form as: J Immunol. 2021 Jun 15; 206(12): 2966–2979. Published online 2021 May 26. doi: 10.4049/jimmunol.2001468

PMCID:: PMC8617036

Abstract Article PDF–1.6M

Select item 850022419.

MKP-1 modulates ubiquitination/phosphorylation of TLR signaling

Jaya Talreja, Christian Bauerfeld, Xiantao Wang, Markus Hafner, Yusen Liu, Lobelia Samavati

Life Sci Alliance. 2021 Dec; 4(12): e202101137. Published online 2021 Sep 27. doi: 10.26508/lsa.202101137

PMCID:: PMC8500224

Abstract Article PDF–1.9M

Select item 825615820.

Early p38 Activation Regulated by MKP-1 Is Determinant for High Levels of IL-10 Expression Through TLR2 Activation

Sara Francisco, Alicia Arranz, Javier Merino, Carmen Punzón, Rosario Perona, Manuel Fresno

Front Immunol. 2021; 12: 660065. Published online 2021 Jun 21. doi: 10.3389/fimmu.2021.660065

PMCID:: PMC8256158

Abstract Article PDF–2.9M

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