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Select item 107835251.

An intronic RNA element modulates Factor VIII exon-16 splicing

Victor Tse, Guillermo Chacaltana, Martin Gutierrez, Nicholas M Forino, Arcelia G Jimenez, Hanzhang Tao, Phong H Do, Catherine Oh, Priyanka Chary, Isabel Quesada, Antonia Hamrick, Sophie Lee, Michael D Stone, Jeremy R Sanford

Nucleic Acids Res. 2024 Jan 11; 52(1): 300–315. Published online 2023 Nov 14. doi: 10.1093/nar/gkad1034

PMCID:: PMC10783525

Abstract Article PDF–2.2M

Select item 101967642.

Mechano-covalent protection of coagulation factor VIII by von Willebrand factor

Diego Butera, Haoqing Jerry Wang, Heng-Giap Woon, Yunduo Charles Zhao, Lining Arnold Ju, Philip J. Hogg

Blood Adv. 2023 May 23; 7(10): 2117–2128. Published online 2022 Oct 18. doi: 10.1182/bloodadvances.2022008650

PMCID:: PMC10196764

Abstract Article PDF–1.3M

Select item 101399403.

Factor VIII mutated with Lys1813Ala within the factor IXa-binding region enhances intrinsic coagulation potential

Yuto Nakajima, Masahiro Takeyama, Akihisa Oda, Naruto Shimonishi, Keiji Nogami

Blood Adv. 2023 Apr 25; 7(8): 1436–1445. Published online 2022 Nov 4. doi: 10.1182/bloodadvances.2022008187

PMCID:: PMC10139940

Abstract Article PDF–955K

Select item 98900174.

Translational readthrough at F8 nonsense variants in the factor VIII B domain contributes to residual expression and lowers inhibitor association

Maria Francesca Testa, Silvia Lombardi, Francesco Bernardi, Mattia Ferrarese, Donata Belvini, Paolo Radossi, Giancarlo Castaman, Mirko Pinotti, Alessio Branchini

Haematologica. 2023 Feb 1; 108(2): 472–482. Published online 2022 Aug 4. doi: 10.3324/haematol.2022.281279

PMCID:: PMC9890017

Abstract Article PDF–1.3M

Select item 98504895.

Heterogeneity and reciprocity of FVIII and VWF Expression, and the Response to Shear Stress in Cultured Human Endothelial Cells

Christine Hough, Colleen Notley, Aomei Mo, Barbara Videl, David Lillicrap

J Thromb Haemost. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: J Thromb Haemost. 2022 Nov; 20(11): 2507–2518. Published online 2022 Aug 28. doi: 10.1111/jth.15841

PMCID:: PMC9850489

Abstract Article PDF–702K

Select item 95973846.

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS‐CoV‐2

Cyril Planchais, Alejandra Reyes‐Ruiz, Robin Lacombe, Alessandra Zarantonello, Maxime Lecerf, Margot Revel, Lubka T. Roumenina, Boris P. Atanasov, Hugo Mouquet, Jordan D. Dimitrov

Protein Sci. 2022 Nov; 31(11): e4447. Published online 2022 Oct 26. doi: 10.1002/pro.4447

PMCID:: PMC9597384

Abstract Article PDF–5.4M

Select item 93067277.

Factor VIII as a potential player in cancer pathophysiology

Gillian E. Walker, Simone Merlin, Diego Zanolini, Andrea Vandoni, Alessandro Volpe, Gianluca Gaidano, Guido Valente, Martina Olivero, Antonia Follenzi

J Thromb Haemost. 2022 Mar; 20(3): 648–660. Published online 2022 Jan 11. doi: 10.1111/jth.15611

PMCID:: PMC9306727

Abstract Article PDF–4.6M

Select item 92914718.

Monitoring of different factor VIII replacement products using a factor VIII one‐stage clotting assay on cobas t 511/711 analysers

Carolin Ketteler, Ingrid Hoffmann, Simon Davidson, Andreas Tiede, Nina Richter

Haemophilia. 2021 Nov; 27(6): e704–e712. Published online 2021 Sep 30. doi: 10.1111/hae.14416

PMCID:: PMC9291471

Abstract Article PDF–826K

Select item 87758709.

Ectopic Expression of FVIII in HPCs and MSCs Derived from hiPSCs with Site-Specific Integration of ITGA2B Promoter-Driven BDDF8 Gene in Hemophilia A

Junya Zhao, Miaojin Zhou, Zujia Wang, Lingqian Wu, Zhiqing Hu, Desheng Liang

Int J Mol Sci. 2022 Jan; 23(2): 623. Published online 2022 Jan 6. doi: 10.3390/ijms23020623

PMCID:: PMC8775870

Abstract Article PDF–19M

Select item 858950110.

Serum TNF-α Level as a Possible Predictor of Inhibitor Levels in Severe Hemophilia A

Susi Susanah, Harry Raspati, Nur Melani Sari, Lulu Eva Rakhmilla, Yunia Sribudiani, Octawyana Moestopo, Puspasari Sinaga, Ponpon Idjradinata, Ani Melani Maskoen

Biomed Res Int. 2021; 2021: 6483490. Published online 2021 Nov 5. doi: 10.1155/2021/6483490

PMCID:: PMC8589501

Abstract Article PDF–605K

Select item 852304311.

Role of ADAMTS13, VWF and F8 genes in deep vein thrombosis

Maria Teresa Pagliari, Andrea Cairo, Marco Boscarino, Ilaria Mancini, Emanuela Pappalardo, Paolo Bucciarelli, Ida Martinelli, Frits R. Rosendaal, Flora Peyvandi

PLoS One. 2021; 16(10): e0258675. Published online 2021 Oct 18. doi: 10.1371/journal.pone.0258675

PMCID:: PMC8523043

Abstract Article PDF–597K

Select item 836418112.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 834295813.

Exploring the Complex Role of Coagulation Factor VIII in Chronic Liver Disease

Tirthadipa Pradhan-Sundd, Shweta Gudapati, Tomasz W. Kaminski, Margaret V. Ragni

Cell Mol Gastroenterol Hepatol. 2021; 12(3): 1061–1072. Published online 2021 Mar 8. doi: 10.1016/j.jcmgh.2021.02.014

PMCID:: PMC8342958

Abstract Article PDF–1.6M

Select item 822306514.

Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor

Estelle K. Ronayne, Shaun C. Peters, Joseph S. Gish, Celena Wilson, H. Trent Spencer, Christopher B. Doering, Pete Lollar, P. Clint Spiegel, Jr, Kenneth C. Childers

Front Immunol. 2021; 12: 697602. Published online 2021 Jun 10. doi: 10.3389/fimmu.2021.697602

PMCID:: PMC8223065

Abstract Article PDF–6.2M

Select item 821018415.

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma

Verónica Freire-Benéitez, Nicola Pomella, Thomas O Millner, Anaëlle A Dumas, Maria Victoria Niklison-Chirou, Eleni Maniati, Jun Wang, Vinothini Rajeeve, Pedro Cutillas, Silvia Marino

NAR Cancer. 2021 Mar; 3(1): zcab009. Published online 2021 Mar 22. doi: 10.1093/narcan/zcab009

Correction in:: NAR Cancer. 2021 Jun; 3(2): zcab020.

PMCID:: PMC8210184

Abstract Article PDF–3.4M

Select item 820922916.

Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII

Tiago J. S. Lopes, Ricardo Rios, Tatiane Nogueira, Rodrigo F. Mello

Sci Rep. 2021; 11: 12625. Published online 2021 Jun 16. doi: 10.1038/s41598-021-92201-3

PMCID:: PMC8209229

Abstract Article PDF–3.6M

Select item 807713117.

Genomic alterations in the F8 gene correlating with severe hemophilia A in Egyptian patients

Rehab M. Mosaad, Khalda S. Amr, Eman A. Rabie, Naglaa O. Mostafa, Sonia A. Habib, Ghada Y. El‐Kamah

Mol Genet Genomic Med. 2021 Feb; 9(2): e1575. Published online 2020 Dec 20. doi: 10.1002/mgg3.1575

PMCID:: PMC8077131

Abstract Article PDF–592K

Select item 806299718.

IVIg increases interleukin‐11 levels, which in turn contribute to increased platelets, VWF and FVIII in mice and humans

A. Nguyen, Y. Repesse, M. Ebbo, Y. Allenbach, O. Benveniste, J. M. Vallat, L. Magy, S. Deshayes, G. Maigné, H. de Boysson, A. Karnam, S. Delignat, S. Lacroix‐Desmazes, J. Bayry, A. Aouba

Clin Exp Immunol. 2021 May; 204(2): 258–266. Published online 2021 Feb 22. doi: 10.1111/cei.13580