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Select item 111388431.

Human and rodent type 1 11β-hydroxysteroid dehydrogenases are 7β-hydroxycholesterol dehydrogenases involved in oxysterol metabolism

M. Hult, B. Elleby, N. Shafqat, S. Svensson, A. Rane, H. Jörnvall, L. Abrahmsen, U. Oppermann

Cell Mol Life Sci. 2004 Apr; 61(7-8): 992–999. doi: 10.1007/s00018-003-3476-y

PMCID:: PMC11138843

Abstract Article PDF–218K

Select item 107216922.

11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patients

Sabine Schluessel, Wei Zhang, Hanna Nowotny, Martin Bidlingmaier, Stefan Hintze, Sonja Kunz, Sebastian Martini, Stefan Mehaffey, Peter Meinke, Carl Neuerburg, Ralf Schmidmaier, Benedikt Schoser, Nicole Reisch, Michael Drey

Aging Clin Exp Res. 2023; 35(12): 3073–3083. Published online 2023 Nov 9. doi: 10.1007/s40520-023-02574-w

PMCID:: PMC10721692

Abstract Article PDF–926K

Select item 102444603.

Hyperglycemia-activated 11β-hydroxysteroid dehydrogenase type 1 increases endoplasmic reticulum stress and skin barrier dysfunction

Young Bin Lee, Hyun Jee Hwang, Eunjung Kim, Sung Ha Lim, Choon Hee Chung, Eung Ho Choi

Sci Rep. 2023; 13: 9206. Published online 2023 Jun 6. doi: 10.1038/s41598-023-36294-y

PMCID:: PMC10244460

Abstract Article PDF–4.3M

Select item 97091684.

Inhibition of 11β-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH

Su-Yeon Lee, Sanghwa Kim, Inhee Choi, Yeonhwa Song, Namjeong Kim, Hyung Chul Ryu, Jee Woong Lim, Hyo Jin Kang, Jason Kim, Haeng Ran Seo

Cell Death Dis. 2022 Nov; 13(11): 1011. Published online 2022 Nov 29. doi: 10.1038/s41419-022-05452-x

PMCID:: PMC9709168

Abstract Article PDF–5.1M

Select item 88101095.

Microenvironment-associated gene HSD11B1 may serve as a prognostic biomarker in clear cell renal cell carcinoma: a study based on TCGA, RT‑qPCR, Western blotting, and immunohistochemistry

Di Han, Zhongjie Yu, Hong Zhang, Haipeng Liu, Bin Wang, Donmeng Qian

Bioengineered. 2021; 12(2): 10891–10904. Published online 2021 Nov 30. doi: 10.1080/21655979.2021.1994908

PMCID:: PMC8810109

Abstract Article PDF–3.2M

Select item 85084806.

Association between Selected Polymorphisms rs12086634, rs846910, rs4844880, rs3753519 of 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) and the Presence of Insulin Resistance in the Polish Population of People Living in Upper Silesia

Nikola Szweda-Gandor, Mirosław Śnit, Władysław Grzeszczak

Int J Environ Res Public Health. 2021 Oct; 18(19): 10168. Published online 2021 Sep 27. doi: 10.3390/ijerph181910168

PMCID:: PMC8508480

Abstract Article PDF–329K

Select item 81985797.

Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 Contributes to Epidermal Permeability Barrier Dysfunction in Aged Skin

Beom Jun Kim, Noo Ri Lee, Chung Hyeok Lee, Young Bin Lee, Sung Jay Choe, Solam Lee, Hyun Jee Hwang, Eunjung Kim, Gareth G. Lavery, Kyong-Oh Shin, Kyungho Park, Eung Ho Choi

Int J Mol Sci. 2021 Jun; 22(11): 5750. Published online 2021 May 27. doi: 10.3390/ijms22115750

PMCID:: PMC8198579

Abstract Article PDF–2.1M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78582119.

Influence of labor on direct and indirect determinants of placental 11beta-hydroxysteroid dehydrogenase activity

Hanna Huebner, Kirsten Heussner, Matthias Ruebner, Matthias Schmid, Jennifer Nadal, Joachim Woelfle, Andrea Hartner, Carlos Menendez-Castro, Manfred Rauh, Matthias W. Beckmann, Sven Kehl, Fabian B. Fahlbusch

Arch Gynecol Obstet. 2021; 303(2): 401–408. Published online 2020 Sep 3. doi: 10.1007/s00404-020-05755-4

PMCID:: PMC7858211

Abstract Article PDF–1.1M

Select item 767886410.

Role of 11β-hydroxysteroid dehydrogenase type 1 in the development of atopic dermatitis

Noo Ri Lee, Beom Jun Kim, Chung Hyeok Lee, Young Bin Lee, Solam Lee, Hyun Jee Hwang, Eunjung Kim, Sung Hee Kim, Min-Geol Lee, Sang Eun Lee, Gareth G. Lavery, Eung Ho Choi

Sci Rep. 2020; 10: 20237. Published online 2020 Nov 19. doi: 10.1038/s41598-020-77281-x

PMCID:: PMC7678864

Abstract Article PDF–3.3M

Select item 761165711.

Weight loss increases 11β-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue

Jeremy W. Tomlinson, Jasbir S. Moore, Penny M.S. Clark, Geoff Holder, Lynette Shakespeare, Paul M. Stewart

J Clin Endocrinol Metab. Author manuscript; available in PMC 2021 Sep 14.

Published in final edited form as: J Clin Endocrinol Metab. 2004 Jun 1; 89(6): 2711–6. doi: 10.1210/jc.2003-031376

PMCID:: PMC7611657

Abstract Article PDF–777K

Select item 745364812.

11β-hydroxysteroid dehydrogenase-1 is associated with the activation of hepatic stellate cells in the development of hepatic fibrosis

Wei Xiao, Meng-Hou Lu, Peng-Fei Rong, Hao-Ye Zhang, Jian Gong, Ying-Qiong Peng, Huan-Yu Gong, Zhen-Guo Liu

Mol Med Rep. 2020 Oct; 22(4): 3191–3200. Published online 2020 Aug 7. doi: 10.3892/mmr.2020.11423

PMCID:: PMC7453648

Abstract Article PDF–1.1M

Select item 734188913.

11β hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma

Ryoko Saito, Yasuhiro Miki, Takuto Abe, Eisaku Miyauchi, Jiro Abe, Ren Nanamiya, Chihiro Inoue, Ikuro Sato, Hironobu Sasano

Br J Cancer. 2020 Jul 7; 123(1): 61–71. Published online 2020 Apr 27. doi: 10.1038/s41416-020-0837-3

PMCID:: PMC7341889

Abstract Article PDF–2.1M

Select item 694204414.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 634501015.

11β Hydroxysteroid dehydrogenase – 1 activity in type 2 diabetes mellitus: a comparative study

Ravindra Shukla, Asish Kumar Basu, Biplab Mandal, Pradip Mukhopadhyay, Animesh Maity, Satyam Chakraborty, Praveen Kumar Devrabhai

BMC Endocr Disord. 2019; 19: 15. Published online 2019 Jan 24. doi: 10.1186/s12902-019-0344-9

PMCID:: PMC6345010

Abstract Article PDF–881K

Select item 587139516.

11β-hydroxysteroid dehydrogenase-1 deficiency alters brain energy metabolism in acute systemic inflammation

Manu Verma, Tiina M.J. Kipari, Zhenguang Zhang, Tak Yung Man, Thorsten Forster, Natalie Z.M. Homer, Jonathan R. Seckl, Megan C. Holmes, Karen E. Chapman

Brain Behav Immun. 2018 Mar; 69: 223–234. doi: 10.1016/j.bbi.2017.11.015

PMCID:: PMC5871395

Abstract Article PDF–1.6M

Select item 566346517.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

Select item 563478418.

Clearance of beta-amyloid is facilitated by apolipoprotein E and circulating high-density lipoproteins in bioengineered human vessels

Jerome Robert, Emily B Button, Brian Yuen, Megan Gilmour, Kevin Kang, Arvin Bahrabadi, Sophie Stukas, Wenchen Zhao, Iva Kulic, Cheryl L Wellington

eLife. 2017; 6: e29595. Published online 2017 Oct 10. doi: 10.7554/eLife.29595

PMCID:: PMC5634784

Abstract Article PDF–3.4M

Select item 553161119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 482920320.

Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants

Digna R. Velez, Stephen Fortunato, Poul Thorsen, Salvatore J. Lombardi, Scott M. Williams, Ramkumar Menon

Am J Obstet Gynecol. Author manuscript; available in PMC 2016 Apr 12.

Published in final edited form as: Am J Obstet Gynecol. 2009 Feb; 200(2): 209.e1–209.27. Published online 2008 Nov 18. doi: 10.1016/j.ajog.2008.08.051

PMCID:: PMC4829203

Abstract Article PDF–164K

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