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Select item 96659021.

Suppression of CCL2 angiocrine function by adrenomedullin promotes tumor growth

Akiko Nakayama, Kenneth Anthony Roquid, András Iring, Boris Strilic, Stefan Günther, Min Chen, Lee S. Weinstein, Stefan Offermanns

J Exp Med. 2023 Jan 2; 220(1): e20211628. Published online 2022 Nov 14. doi: 10.1084/jem.20211628

PMCID:: PMC9665902

Abstract Article PDF–8.1M

Select item 91463842.

Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development

Wenjing Xu, Nathan P. Nelson-Maney, László Bálint, Hyouk-Bum Kwon, Reema B. Davis, Danielle C. M. Dy, James M. Dunleavey, Brad St. Croix, Kathleen M. Caron

Int J Mol Sci. 2022 May; 23(10): 5712. Published online 2022 May 20. doi: 10.3390/ijms23105712

PMCID:: PMC9146384

Abstract Article PDF–3.9M

Select item 91374523.

Excess Neuropeptides in Lung Signal through Endothelial Cells to Impair Gas Exchange

Jinhao Xu, Le Xu, Pengfei Sui, Jiyuan Chen, Esteban A. Moya, Patrick Hume, William J. Janssen, Jason M. Duran, Patricia Thistlethwaite, Aaron Carlin, Peter Gulleman, Brandon Banaschewski, Mary Kate Goldy, Jason X.-J. Yuan, Atul Malhotra, Gloria Pryhuber, Laura Crotty-Alexander, Gail Deutsch, Lisa R. Young, Xin Sun

Dev Cell. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Dev Cell. 2022 Apr 11; 57(7): 839–853.e6. Published online 2022 Mar 17. doi: 10.1016/j.devcel.2022.02.023

PMCID:: PMC9137452

Abstract Article PDF–2.9M

Select item 77144044.

Disturbed flow–induced G_s-mediated signaling protects against endothelial inflammation and atherosclerosis

Akiko Nakayama, Julián Albarrán-Juárez, Guozheng Liang, Kenneth Anthony Roquid, András Iring, Sarah Tonack, Min Chen, Oliver J. Müller, Lee S. Weinstein, Stefan Offermanns

JCI Insight. 2020 Dec 3; 5(23): e140485. Published online 2020 Dec 3. doi: 10.1172/jci.insight.140485

PMCID:: PMC7714404

Abstract Article PDF–42M

Select item 74159915.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 65972326.

Shear stress–induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure

Andras Iring, Young-June Jin, Julián Albarrán-Juárez, Mauro Siragusa, ShengPeng Wang, Péter T. Dancs, Akiko Nakayama, Sarah Tonack, Min Chen, Carsten Künne, Anna M. Sokol, Stefan Günther, Alfredo Martínez, Ingrid Fleming, Nina Wettschureck, Johannes Graumann, Lee S. Weinstein, Stefan Offermanns

J Clin Invest. 2019 Jul 1; 129(7): 2775–2791. Published online 2019 Jun 17. doi: 10.1172/JCI123825

PMCID:: PMC6597232

Abstract Article PDF–8.8M

Select item 63445437.

CGRP-CRLR/RAMP1 signal is important for stress-induced hematopoiesis

Akira Suekane, Yusuke Saito, Shingo Nakahata, Tomonaga Ichikawa, Honami Ogoh, Kazutake Tsujikawa, Kazuhiro Morishita

Sci Rep. 2019; 9: 429. Published online 2019 Jan 23. doi: 10.1038/s41598-018-36796-0

PMCID:: PMC6344543

Abstract Article PDF–1.6M

Select item 61229778.

hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia

Duncan I. Mackie, Fuad Al Mutairi, Reema B. Davis, Daniel O. Kechele, Natalie R. Nielsen, Joshua C. Snyder, Marc G. Caron, Harvey J. Kliman, Jonathan S. Berg, John Simms, David R. Poyner, Kathleen M. Caron

J Exp Med. 2018 Sep 3; 215(9): 2339–2353. doi: 10.1084/jem.20180528

PMCID:: PMC6122977

Abstract Article PDF–3.3M

Select item 59859509.

Notch/CollagenV/CalcR reciprocal signalling retains muscle stem cells in their niche

Meryem B. Baghdadi, David Castel, Léo Machado, So-ichiro Fukada, David E. Birk, Frederic Relaix, Shahragim Tajbakhsh, Philippos Mourikis

Nature. Author manuscript; available in PMC 2018 Nov 23.

Published in final edited form as: Nature. 2018 May; 557(7707): 714–718. Published online 2018 May 23. doi: 10.1038/s41586-018-0144-9

PMCID:: PMC5985950

Abstract Article PDF–4.6M

Select item 570654410.

Cardiovascular effects of exogenous adrenomedullin and CGRP in Ramp and Calcrl deficient mice

J.B. Pawlak, S.E. Wetzel-Strong, M.K. Dunn, K.M. Caron

Peptides. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: Peptides. 2017 Feb; 88: 1–7. Published online 2016 Dec 8. doi: 10.1016/j.peptides.2016.12.002

PMCID:: PMC5706544

Abstract Article PDF–672K

Select item 551917011.

Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation

Mahita Kadmiel, Brooke C. Matson, Scott T. Espenschied, Patricia M. Lenhart, Kathleen M. Caron

PLoS One. 2017; 12(7): e0181597. Published online 2017 Jul 20. doi: 10.1371/journal.pone.0181597

PMCID:: PMC5519170

Abstract Article PDF–27M

Select item 535848812.

Lymphatic deletion of calcitonin receptor–like receptor exacerbates intestinal inflammation

Reema B. Davis, Daniel O. Kechele, Elizabeth S. Blakeney, John B. Pawlak, Kathleen M. Caron

JCI Insight. 2017 Mar 23; 2(6): e92465. Published online 2017 Mar 23. doi: 10.1172/jci.insight.92465

PMCID:: PMC5358488

Abstract Article PDF–1.8M

Select item 498282313.

Endothelial restoration of receptor activity-modifying protein 2 is sufficient to rescue lethality, but survivors develop dilated cardiomyopathy

Daniel O. Kechele, William P. Dunworth, Claire E. Trincot, Sarah E. Wetzel-Strong, Manyu Li, Hong Ma, Jiandong Liu, Kathleen M. Caron

Hypertension. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Hypertension. 2016 Sep; 68(3): 667–677. Published online 2016 Jul 11. doi: 10.1161/HYPERTENSIONAHA.116.07191

PMCID:: PMC4982823

Abstract Article PDF–2.5M

Select item 409214814.

Deficiency of RAMP1 Attenuates Antigen-Induced Airway Hyperresponsiveness in Mice

Manyu Li, Sarah E. Wetzel-Strong, Xiaoyang Hua, Stephen L. Tilley, Erin Oswald, Matthew F. Krummel, Kathleen M. Caron

PLoS One. 2014; 9(7): e102356. Published online 2014 Jul 10. doi: 10.1371/journal.pone.0102356

PMCID:: PMC4092148

Abstract Article PDF–4.3M

Select item 366881615.

Fetal-derived adrenomedullin mediates the innate immune milieu of the placenta

Manyu Li, Nicole M.J. Schwerbrock, Patricia M. Lenhart, Kimberly L. Fritz-Six, Mahita Kadmiel, Kathleen S. Christine, Daniel M. Kraus, Scott T. Espenschied, Helen H. Willcockson, Christopher P. Mack, Kathleen M. Caron

J Clin Invest. 2013 Jun 3; 123(6): 2408–2420. Published online 2013 May 1. doi: 10.1172/JCI67039

PMCID:: PMC3668816

Abstract Article PDF–6.3M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 344448017.

Characteristics of Multi-Organ Lymphangiectasia Resulting from Temporal Deletion of Calcitonin Receptor-Like Receptor in Adult Mice

Samantha L. Hoopes, Helen H. Willcockson, Kathleen M. Caron

PLoS One. 2012; 7(9): e45261. Published online 2012 Sep 17. doi: 10.1371/journal.pone.0045261

PMCID:: PMC3444480

Abstract Article PDF–4.1M

Select item 341563718.

Calcitonin and calcitonin receptor-like receptors: common themes with family B GPCRs?

James Barwell, Joseph J Gingell, Harriet A Watkins, Julia K Archbold, David R Poyner, Debbie L Hay

Br J Pharmacol. 2012 May; 166(1): 51–65. doi: 10.1111/j.1476-5381.2011.01525.x

PMCID:: PMC3415637

Abstract Article PDF–4.8M

Select item 334138019.

Intermedin Stabilized Endothelial Barrier Function and Attenuated Ventilator-induced Lung Injury in Mice

Holger Christian Müller-Redetzky, Wolfgang Kummer, Uwe Pfeil, Katharina Hellwig, Daniel Will, Renate Paddenberg, Christoph Tabeling, Stefan Hippenstiel, Norbert Suttorp, Martin Witzenrath

PLoS One. 2012; 7(5): e35832. Published online 2012 May 1. doi: 10.1371/journal.pone.0035832

PMCID:: PMC3341380

Abstract Article PDF–5.9M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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