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Items: 1 to 20 of 150

1.
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout mice
Satvik Mareedu, Nadezhda Fefelova, Cristi L. Galindo, Goutham Prakash, Risa Mukai, Junichi Sadoshima, Lai-Hua Xie, Gopal J. Babu
JCI Insight. 2024 May 8; 9(9): e170185. Published online 2024 Apr 2. doi: 10.1172/jci.insight.170185
PMCID:
PMC11141945
AbstractArticlePDF–2.7M
2.
Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue
T. Haenggi, J. -M. Fritschy
Cell Mol Life Sci. 2006 Jul; 63(14): 1614–1631. Published online 2006 May 15. doi: 10.1007/s00018-005-5461-0
PMCID:
PMC11136313
AbstractArticlePDF–626K
3.
A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET
Joanne M. Tang, Andrew McClennan, Linshan Liu, Jennifer Hadway, John A. Ronald, Justin W. Hicks, Lisa Hoffman, Udunna C. Anazodo
Int J Mol Sci. 2023 Apr; 24(8): 7522. Published online 2023 Apr 19. doi: 10.3390/ijms24087522
PMCID:
PMC10144317
AbstractArticlePDF–3.8M
4.
Endogenous bioluminescent reporters reveal a sustained increase in utrophin gene expression upon EZH2 and ERK1/2 inhibition
Hannah J. Gleneadie, Beatriz Fernandez-Ruiz, Alessandro Sardini, Mathew Van de Pette, Andrew Dimond, Rab K. Prinjha, James McGinty, Paul M. W. French, Hakan Bagci, Matthias Merkenschlager, Amanda G. Fisher
Commun Biol. 2023; 6: 318. Published online 2023 Mar 25. doi: 10.1038/s42003-023-04666-9
PMCID:
PMC10039851
AbstractArticlePDF–3.3M
5.
Pharmacological TRPC6 inhibition improves survival and muscle function in mice with Duchenne muscular dystrophy
Brian L. Lin, Joseph Y. Shin, William P.D. Jeffreys, Nadan Wang, Clarisse A. Lukban, Megan C. Moorer, Esteban Velarde, Olivia A. Hanselman, Seoyoung Kwon, Suraj Kannan, Ryan C. Riddle, Christopher W. Ward, Steven S. Pullen, Antonio Filareto, David A. Kass
JCI Insight. 2022 Oct 10; 7(19): e158906. Published online 2022 Oct 10. doi: 10.1172/jci.insight.158906
PMCID:
PMC9675567
AbstractArticlePDF–6.1M
6.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
7.
Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression
Angelina M. Georgieva, Xinyue Guo, Marek Bartkuhn, Stefan Günther, Carsten Künne, Christian Smolka, Ann Atzberger, Ulrich Gärtner, Kamel Mamchaoui, Eva Bober, Yonggang Zhou, Xuejun Yuan, Thomas Braun
Nat Commun. 2022; 13: 4184. Published online 2022 Jul 20. doi: 10.1038/s41467-022-31798-z
PMCID:
PMC9300598
AbstractArticlePDF–3.5M
8.
Proteins implicated in muscular dystrophy and cancer are functional constituents of the centrosome
Lilli Winter, Monika Kustermann, Büsra Ernhofer, Harald Höger, Reginald E Bittner, Wolfgang M Schmidt
Life Sci Alliance. 2022 Nov; 5(11): e202201367. Published online 2022 Jul 5. doi: 10.26508/lsa.202201367
PMCID:
PMC9259872
AbstractArticlePDF–3.1M
9.
Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression
Min Ho Song, Jimeen Yoo, Jae Gyun Oh, Hyun Kook, Woo Jin Park, Dongtak Jeong
Front Cardiovasc Med. 2022; 9: 763544. Published online 2022 Apr 26. doi: 10.3389/fcvm.2022.763544
PMCID:
PMC9088811
AbstractArticlePDF–4.4M
10.
CD38‐NADase is a new major contributor to Duchenne muscular dystrophic phenotype
Antoine de Zélicourt, Abdallah Fayssoil, Mbarka Dakouane‐Giudicelli, Isley De Jesus, Ahmed Karoui, Faouzi Zarrouki, Florence Lefebvre, Arnaud Mansart, Jean‐Marie Launay, Jerome Piquereau, Mariana G Tarragó, Marcel Bonay, Anne Forand, Sophie Moog, France Piétri‐Rouxel, Elise Brisebard, Claudia C S Chini, Sonu Kashyap, Matthew J Fogarty, Gary C Sieck, Mathias Mericskay, Eduardo N Chini, Ana Maria Gomez, José‐Manuel Cancela, Sabine de la Porte
EMBO Mol Med. 2022 May; 14(5): e12860. Published online 2022 Mar 17. doi: 10.15252/emmm.202012860
PMCID:
PMC9081905
AbstractArticlePDF–5.2M
11.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
12.
Resolvin-D2 targets myogenic cells and improves muscle regeneration in Duchenne muscular dystrophy
Junio Dort, Zakaria Orfi, Paul Fabre, Thomas Molina, Talita C. Conte, Karine Greffard, Ornella Pellerito, Jean-François Bilodeau, Nicolas A. Dumont
Nat Commun. 2021; 12: 6264. Published online 2021 Oct 29. doi: 10.1038/s41467-021-26516-0
PMCID:
PMC8556273
AbstractArticlePDF–4.6M
13.
Dystrophin involvement in peripheral circadian SRF signalling
Corinne A Betts, Aarti Jagannath, Tirsa LE van Westering, Melissa Bowerman, Subhashis Banerjee, Jinhong Meng, Maria Sofia Falzarano, Lara Cravo, Graham McClorey, Katharina E Meijboom, Amarjit Bhomra, Wooi Fang Lim, Carlo Rinaldi, John R Counsell, Katarzyna Chwalenia, Elizabeth O’Donovan, Amer F Saleh, Michael J Gait, Jennifer E Morgan, Alessandra Ferlini, Russell G Foster, Matthew JA Wood
Life Sci Alliance. 2021 Oct; 4(10): e202101014. Published online 2021 Aug 13. doi: 10.26508/lsa.202101014
PMCID:
PMC8363758
AbstractArticlePDF–2.3M
14.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
15.
Plasma lipidomic analysis shows a disease progression signature in mdx mice
Roula Tsonaka, Alexandre Seyer, Annemieke Aartsma-Rus, Pietro Spitali
Sci Rep. 2021; 11: 12993. Published online 2021 Jun 21. doi: 10.1038/s41598-021-92406-6
PMCID:
PMC8217252
AbstractArticlePDF–3.4M
16.
Early Inflammation in Muscular Dystrophy Differs between Limb and Respiratory Muscles and Increases with Dystrophic Severity
Zachary M. Howard, Jeovanna Lowe, Anton J. Blatnik, 3rd, Deztani Roberts, Arthur H.M. Burghes, Shyam S. Bansal, Jill A. Rafael-Fortney
Am J Pathol. 2021 Apr; 191(4): 730–747. doi: 10.1016/j.ajpath.2021.01.008
PMCID:
PMC8147105
AbstractArticlePDF–4.4M
17.
Micro-dystrophin gene therapy prevents heart failure in an improved Duchenne muscular dystrophy cardiomyopathy mouse model
Zachary M. Howard, Lisa E. Dorn, Jeovanna Lowe, Megan D. Gertzen, Pierce Ciccone, Neha Rastogi, Guy L. Odom, Federica Accornero, Jeffrey S. Chamberlain, Jill A. Rafael-Fortney
JCI Insight. 2021 Apr 8; 6(7): e146511. Published online 2021 Apr 8. doi: 10.1172/jci.insight.146511
PMCID:
PMC8119181
AbstractArticlePDF–1.6M
18.
Differential Expression of Utrophin‐A and ‐B Promoters in the Central Nervous System (CNS) of Normal and Dystrophic mdx Mice
Santhosh M. Baby, Sasha Bogdanovich, Gabriel Willmann, Utpal Basu, Olga Lozynska, Tejvir S. Khurana
Brain Pathol. 2010 Mar; 20(2): 323–342. Published online 2009 May 27. doi: 10.1111/j.1750-3639.2009.00275.x
PMCID:
PMC8095546
AbstractArticlePDF–2.2M
19.
Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity
Justin P. Hardee, Karen J.B. Martins, Paula M. Miotto, James G. Ryall, Stefan M. Gehrig, Boris Reljic, Timur Naim, Jin D. Chung, Jen Trieu, Kristy Swiderski, Ashleigh M. Philp, Andrew Philp, Matthew J. Watt, David A. Stroud, Rene Koopman, Gregory R. Steinberg, Gordon S. Lynch
Mol Metab. 2021 Mar; 45: 101157. Published online 2020 Dec 24. doi: 10.1016/j.molmet.2020.101157
PMCID:
PMC7811171
AbstractArticlePDF–4.9M
20.
Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice
Xiaodong Mu, Chi-Yi Lin, William S. Hambright, Ying Tang, Sudheer Ravuri, Aiping Lu, Polina Matre, Wanqun Chen, Xueqin Gao, Yan Cui, Ling Zhong, Bing Wang, Johnny Huard
Aging (Albany NY) 2020 Dec 31; 12(24): 24853–24871. Published online 2020 Dec 23. doi: 10.18632/aging.202413
PMCID:
PMC7803538
AbstractArticlePDF–2.2M

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