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Items: 1 to 20 of 858

1.
Caveolar targeting links Kv1.3 with the insulin-dependent adipocyte physiology
Mireia Pérez-Verdaguer, Jesusa Capera, María Ortego-Domínguez, Joanna Bielanska, Núria Comes, Rafael J. Montoro, Marta Camps, Antonio Felipe
Cell Mol Life Sci. 2018 Nov; 75(21): 4059–4075. Published online 2018 Jun 11. doi: 10.1007/s00018-018-2851-7
PMCID:
PMC11105548
AbstractArticlePDF–2.2M
2.
Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
Vanessa Yu, Fiona Yong, Angellica Marta, Sanjay Khadayate, Adrien Osakwe, Supriyo Bhattacharya, Sneha S. Varghese, Pauline Chabosseau, Sayed M. Tabibi, Keran Chen, Eleni Georgiadou, Nazia Parveen, Mara Suleiman, Zoe Stamoulis, Lorella Marselli, Carmela De Luca, Marta Tesi, Giada Ostinelli, Luis Delgadillo-Silva, Xiwei Wu, Yuki Hatanaka, Alex Montoya, James Elliott, Bhavik Patel, Nikita Demchenko, Chad Whilding, Petra Hajkova, Pavel Shliaha, Holger Kramer, Yusuf Ali, Piero Marchetti, Robert Sladek, Sangeeta Dhawan, Dominic J. Withers, Guy A. Rutter, Steven J. Millership
Diabetologia. 2024; 67(6): 1079–1094. Published online 2024 Mar 21. doi: 10.1007/s00125-024-06123-6
PMCID:
PMC11058053
AbstractArticlePDF–7.7M
3.
TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet
Sarah M. Graff, Arya Y. Nakhe, Prasanna K. Dadi, Matthew T. Dickerson, Jordyn R. Dobson, Karolina E. Zaborska, Chloe E. Ibsen, Regan B. Butterworth, Nicholas C. Vierra, David A. Jacobson
Cell Rep. Author manuscript; available in PMC 2024 Mar 25.
Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113673. Published online 2024 Jan 10. doi: 10.1016/j.celrep.2024.113673
PMCID:
PMC10961926
AbstractArticlePDF–2.0M
4.
NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover
Bei Liu, Duanyi Hua, Linyan Shen, Tingting Li, Zheying Tao, Chenyang Fu, Zhongzheng Tang, Jie Yang, Li Zhang, Aifang Nie, Yiran Jiang, Jiqiu Wang, Yang Li, Yanyun Gu, Guang Ning
Theranostics. 2024; 14(5): 2058–2074. Published online 2024 Feb 24. doi: 10.7150/thno.90946
PMCID:
PMC10945349
AbstractArticlePDF–9.7M
5.
Complement Cascade Proteins Correlate with Fibrosis and Inflammation in Early-Stage Type 1 Diabetic Kidney Disease in the Ins2Akita Mouse Model
Aggeliki Tserga, Jean Sébastien Saulnier-Blache, Kostantinos Palamaris, Despoina Pouloudi, Harikleia Gakiopoulou, Jerome Zoidakis, Joost Peter Schanstra, Antonia Vlahou, Manousos Makridakis
Int J Mol Sci. 2024 Feb; 25(3): 1387. Published online 2024 Jan 23. doi: 10.3390/ijms25031387
PMCID:
PMC10855735
AbstractArticlePDF–5.0M
6.
Gestational diabetes in mice induces hematopoietic memory that affects the long-term health of the offspring
Vinothini Govindarajah, Masahide Sakabe, Samantha Good, Michael Solomon, Ashok Arasu, Nong Chen, Xuan Zhang, H. Leighton Grimes, Ady Kendler, Mei Xin, Damien Reynaud
J Clin Invest. 2024 Jan 16; 134(2): e169730. Published online 2024 Jan 16. doi: 10.1172/JCI169730
PMCID:
PMC10786695
AbstractArticlePDF–1.9M
7.
A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding
Haopeng Lin, Kunimasa Suzuki, Nancy Smith, Xi Li, Lisa Nalbach, Sonia Fuentes, Aliya F. Spigelman, Xiao-Qing Dai, Austin Bautista, Mourad Ferdaoussi, Saloni Aggarwal, Andrew R. Pepper, Leticia P. Roma, Emmanuel Ampofo, Wen-hong Li, Patrick E. MacDonald
Nat Commun. 2024; 15: 334. Published online 2024 Jan 6. doi: 10.1038/s41467-023-44589-x
PMCID:
PMC10771529
AbstractArticlePDF–3.6M
8.
Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes
Samuel Philip Nobs, Aleksandra A. Kolodziejczyk, Lital Adler, Nir Horesh, Christine Botscharnikow, Ella Herzog, Gayatree Mohapatra, Sophia Hejndorf, Ryan-James Hodgetts, Igor Spivak, Lena Schorr, Leviel Fluhr, Denise Kviatcovsky, Anish Zacharia, Suzanne Njuki, Dinorah Barasch, Noa Stettner, Mally Dori-Bachash, Alon Harmelin, Alexander Brandis, Tevie Mehlman, Ayelet Erez, Yiming He, Sara Ferrini, Jens Puschhof, Hagit Shapiro, Manfred Kopf, Arieh Moussaieff, Suhaib K. Abdeen, Eran Elinav
Nature. 2023; 624(7992): 645–652. Published online 2023 Dec 13. doi: 10.1038/s41586-023-06803-0
PMCID:
PMC10733144
AbstractArticlePDF–13M
9.
TFEB and TFE3 control glucose homeostasis by regulating insulin gene expression
Adrien Pasquier, Nunzia Pastore, Luca D'Orsi, Rita Colonna, Alessandra Esposito, Veronica Maffia, Rossella De Cegli, Margherita Mutarelli, Susanna Ambrosio, Gennaro Tufano, Antonio Grimaldi, Marcella Cesana, Davide Cacchiarelli, Nathalie Delalleau, Gennaro Napolitano, Andrea Ballabio
EMBO J. 2023 Nov; 42(21): e113928. Published online 2023 Sep 15. doi: 10.15252/embj.2023113928
PMCID:
PMC10620765
AbstractArticlePDF–9.0M
10.
Inhibition of neutrophil extracellular trap formation alleviates vascular dysfunction in type 1 diabetic mice
Chao Liu, Srilakshmi Yalavarthi, Ajay Tambralli, Lixia Zeng, Christine E. Rysenga, Nikoo Alizadeh, Lucas Hudgins, Wenying Liang, Somanathapura K. NaveenKumar, Hui Shi, Miriam A. Shelef, Kevin B. Atkins, Subramaniam Pennathur, Jason S. Knight
Sci Adv. 2023 Oct 27; 9(43): eadj1019. Published online 2023 Oct 25. doi: 10.1126/sciadv.adj1019
PMCID:
PMC10599623
AbstractArticlePDF–1.3M
11.
Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism
Angela Pelligra, Jessica Mrugala, Kerstin Griess, Philip Kirschner, Oliver Nortmann, Barbara Bartosinska, Andrea Köster, Natalia I. Krupenko, Dominik Gebel, Philipp Westhoff, Bodo Steckel, Daniel Eberhard, Diran Herebian, Bengt-Frederik Belgardt, Jürgen Schrader, Andreas P.M. Weber, Sergey A. Krupenko, Eckhard Lammert
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112615. Published online 2023 Jun 8. doi: 10.1016/j.celrep.2023.112615
Correction in:
Cell Rep. 2023 Jul 25; 42(7): 112703.
PMCID:
PMC10592470
AbstractArticlePDF–3.2M
12.
Stromal Interaction Molecule 1 Maintains β-Cell Identity and Function in Female Mice Through Preservation of G-Protein–Coupled Estrogen Receptor 1 Signaling
Paul Sohn, Madeline R. McLaughlin, Preethi Krishnan, Wenting Wu, Marjan Slak Rupnik, Akira Takasu, Toshiya Senda, Chih-Chun Lee, Tatsuyoshi Kono, Carmella Evans-Molina
Diabetes. 2023 Oct; 72(10): 1433–1445. Published online 2023 Jul 21. doi: 10.2337/db22-0988
PMCID:
PMC10545557
AbstractArticlePDF–3.1M
13.
SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells
Hitoshi Iida, Tatsuyoshi Kono, Chih-Chun Lee, Preethi Krishnan, Matthew C. Arvin, Staci A. Weaver, Timothy S. Jarvela, Renato C. S. Branco, Madeline R. McLaughlin, Robert N. Bone, Xin Tong, Peter Arvan, Iris Lindberg, Carmella Evans-Molina
Diabetologia. 2023; 66(11): 2042–2061. Published online 2023 Aug 4. doi: 10.1007/s00125-023-05979-4
PMCID:
PMC10542743
AbstractArticlePDF–2.3M
14.
NEUROD1 reinforces endocrine cell fate acquisition in pancreatic development
Romana Bohuslavova, Valeria Fabriciova, Ondrej Smolik, Laura Lebrón-Mora, Pavel Abaffy, Sarka Benesova, Daniel Zucha, Lukas Valihrach, Zuzana Berkova, Frantisek Saudek, Gabriela Pavlinkova
Nat Commun. 2023; 14: 5554. Published online 2023 Sep 9. doi: 10.1038/s41467-023-41306-6
PMCID:
PMC10492842
AbstractArticlePDF–15M
15.
Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
Wilma Tixi, Maricela Maldonado, Ya-Ting Chang, Amy Chiu, Wilson Yeung, Nazia Parveen, Michael S Nelson, Ryan Hart, Shihao Wang, Wu Jih Hsu, Patrick Fueger, Janel L Kopp, Mark O Huising, Sangeeta Dhawan, Hung Ping Shih
eLife. 2023; 12: e90006. Published online 2023 Aug 23. doi: 10.7554/eLife.90006
PMCID:
PMC10482429
AbstractArticlePDF–26M
16.
Progressive Thinning of Retinal Nerve Fiber Layer/Ganglion Cell Layer (RNFL/GCL) as Biomarker and Pharmacological Target of Diabetic Retinopathy
Gianpaolo Zerbini, Silvia Maestroni, Ilaria Viganò, Andrea Mosca, Renata Paleari, Daniela Gabellini, Silvia Galbiati, Paolo Rama
Int J Mol Sci. 2023 Aug; 24(16): 12672. Published online 2023 Aug 11. doi: 10.3390/ijms241612672
PMCID:
PMC10454227
AbstractArticlePDF–4.1M
17.
The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity
Eliana Toren, Jessica D. Kepple, Kristen V. Coutinho, Samuel O. Poole, Iztiba M. Deeba, Tanya H. Pierre, Yanping Liu, Maigen M. Bethea, Chad S. Hunter
Mol Metab. 2023 Oct; 76: 101785. Published online 2023 Aug 1. doi: 10.1016/j.molmet.2023.101785
PMCID:
PMC10448474
AbstractArticlePDF–4.8M
18.
Disrupted glucose homeostasis and glucagon and insulin secretion defects in Robo βKO mice
Melissa T. Adams, Bayley J. Waters, Sutichot D. Nimkulrat, Barak Blum
FASEB J. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: FASEB J. 2023 Aug; 37(8): e23106. doi: 10.1096/fj.202200705RR
PMCID:
PMC10436995
AbstractArticlePDF–1.4M
19.
Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia
Johanna L. St-Louis, Khadija El Jellas, Kelly Velasco, Brittany A. Slipp, Jiang Hu, Geir Helgeland, Solrun J. Steine, Dario F. De Jesus, Rohit N. Kulkarni, Anders Molven
J Biol Chem. 2023 Aug; 299(8): 104986. Published online 2023 Jun 29. doi: 10.1016/j.jbc.2023.104986
PMCID:
PMC10407745
AbstractArticlePDF–1.8M
20.
Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain
Vladimir Abarinov, Joshua A. Levine, Angela J. Churchill, Bryce Hopwood, Cailin S. Deiter, Michelle A. Guney, Kristen L. Wells, Jessica M. Schrunk, Yuchun Guo, Jennifer Hammelman, David K. Gifford, Mark A. Magnuson, Hynek Wichterle, Lori Sussel
Genes Dev. 2023 Jun 1; 37(11-12): 490–504. doi: 10.1101/gad.350569.123
PMCID:
PMC10393193
AbstractArticlePDF–22M

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