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Items: 1 to 20 of 101

1.
Tgfbr1 controls developmental plasticity between the hindlimb and external genitalia by remodeling their regulatory landscape
Anastasiia Lozovska, Artemis G. Korovesi, André Dias, Alexandre Lopes, Donald A. Fowler, Gabriel G. Martins, Ana Nóvoa, Moisés Mallo
Nat Commun. 2024; 15: 2509. Published online 2024 Mar 20. doi: 10.1038/s41467-024-46870-z
PMCID:
PMC10954616
AbstractArticlePDF–9.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer
Luis Puelles, Matias Hidalgo-Sánchez
Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769
PMCID:
PMC10253667
AbstractArticlePDF–6.8M
4.
Dynamic 3D Chromatin Architecture Contributes to Enhancer Specificity and Limb Morphogenesis
Bjørt K. Kragesteen, Malte Spielmann, Christina Paliou, Verena Heinrich, Robert Schöpflin, Andrea Esposito, Carlo Annunziatella, Simona Bianco, Andrea M. Chiariello, Ivana Jerković, Izabela Harabula, Philine Guckelberger, Michael Pechstein, Lars Wittler, Wing-Lee Chan, Martin Franke, Darío G. Lupiáñez, Katerina Kraft, Bernd Timmermann, Martin Vingron, Axel Visel, Mario Nicodemi, Stefan Mundlos, Guillaume Andrey
Nat Genet. Author manuscript; available in PMC 2023 May 3.
Published in final edited form as: Nat Genet. 2018 Oct; 50(10): 1463–1473. Published online 2018 Sep 27. doi: 10.1038/s41588-018-0221-x
PMCID:
PMC10154999
AbstractArticlePDF–4.1M
5.
Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man
Hironori Bando, Michelle L Brinkmeier, Frederic Castinetti, Qing Fang, Mi-Sun Lee, Alexandru Saveanu, Frédérique Albarel, Clémentine Dupuis, Thierry Brue, Sally A Camper
Hum Mol Genet. 2023 Feb 1; 32(3): 367–385. Published online 2022 Aug 11. doi: 10.1093/hmg/ddac192
PMCID:
PMC9851746
AbstractArticlePDF–3.5M
6.
Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancer
Raquel Rouco, Olimpia Bompadre, Antonella Rauseo, Olivier Fazio, Rodrigue Peraldi, Fabrizio Thorel, Guillaume Andrey
Nat Commun. 2021; 12: 7235. Published online 2021 Dec 13. doi: 10.1038/s41467-021-27492-1
PMCID:
PMC8668926
AbstractArticlePDF–8.4M
7.
Tbx4 function during hindlimb development reveals a mechanism that explains the origins of proximal limb defects
Veronique Duboc, Fatima A. Sulaiman, Eleanor Feneck, Anna Kucharska, Donald Bell, Muriel Holder-Espinasse, Malcolm P. O. Logan
Development. 2021 Oct 1; 148(19): dev199580. Published online 2021 Sep 24. doi: 10.1242/dev.199580
PMCID:
PMC8497778
AbstractArticle
8.
GATA3 is essential for separating patterning domains during facial morphogenesis
Makoto Abe, Timothy C. Cox, Anthony B. Firulli, Stanley M. Kanai, Jacob Dahlka, Kim-Chew Lim, James Douglas Engel, David E. Clouthier
Development. 2021 Sep 1; 148(17): dev199534. Published online 2021 Sep 7. doi: 10.1242/dev.199534
PMCID:
PMC8451945
AbstractArticle
9.
Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans
Angelica Gualtieri, Nikolina Kyprianou, Louise C. Gregory, Maria Lillina Vignola, James G. Nicholson, Rachael Tan, Shin-ichi Inoue, Valeria Scagliotti, Pedro Casado, James Blackburn, Fernando Abollo-Jimenez, Eugenia Marinelli, Rachael E. J. Besser, Wolfgang Högler, I. Karen Temple, Justin H. Davies, Andrey Gagunashvili, Iain C.A.F. Robinson, Sally A. Camper, Shannon W. Davis, Pedro R. Cutillas, Evelien F. Gevers, Yoko Aoki, Mehul T. Dattani, Carles Gaston-Massuet
Nat Commun. 2021; 12: 2028. Published online 2021 Apr 1. doi: 10.1038/s41467-021-21712-4
PMCID:
PMC8016902
AbstractArticlePDF–15M
10.
Accelerating functional gene discovery in osteoarthritis
Natalie C. Butterfield, Katherine F. Curry, Julia Steinberg, Hannah Dewhurst, Davide Komla-Ebri, Naila S. Mannan, Anne-Tounsia Adoum, Victoria D. Leitch, John G. Logan, Julian A. Waung, Elena Ghirardello, Lorraine Southam, Scott E. Youlten, J. Mark Wilkinson, Elizabeth A. McAninch, Valerie E. Vancollie, Fiona Kussy, Jacqueline K. White, Christopher J. Lelliott, David J. Adams, Richard Jacques, Antonio C. Bianco, Alan Boyde, Eleftheria Zeggini, Peter I. Croucher, Graham R. Williams, J. H. Duncan Bassett
Nat Commun. 2021; 12: 467. Published online 2021 Jan 20. doi: 10.1038/s41467-020-20761-5
Correction in:
Nat Commun. 2021; 12: 3302.
PMCID:
PMC7817695
AbstractArticlePDF–8.0M
11.
Spatiotemporal cellular movement and fate decisions during first pharyngeal arch morphogenesis
Yuan Yuan, Yong-hwee Eddie Loh, Xia Han, Jifan Feng, Thach-Vu Ho, Jinzhi He, Junjun Jing, Kimberly Groff, Alan Wu, Yang Chai
Sci Adv. 2020 Dec; 6(51): eabb0119. Published online 2020 Dec 16. doi: 10.1126/sciadv.abb0119
PMCID:
PMC7744069
AbstractArticlePDF–3.7M
12.
A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation
André Dias, Anastasiia Lozovska, Filip J Wymeersch, Ana Nóvoa, Anahi Binagui-Casas, Daniel Sobral, Gabriel G Martins, Valerie Wilson, Moises Mallo
eLife. 2020; 9: e56615. Published online 2020 Jun 29. doi: 10.7554/eLife.56615
PMCID:
PMC7324159
AbstractArticlePDF–16M
13.
Delineating the early transcriptional specification of the mammalian trachea and esophagus
Akela Kuwahara, Ace E Lewis, Coohleen Coombes, Fang-Shiuan Leung, Michelle Percharde, Jeffrey O Bush
eLife. 2020; 9: e55526. Published online 2020 Jun 9. doi: 10.7554/eLife.55526
PMCID:
PMC7282815
AbstractArticlePDF–4.9M
14.
Gene Regulatory and Expression Differences between Mouse and Pig Limb Buds Provide Insights into the Evolutionary Emergence of Artiodactyl Traits
Virginie Tissières, Florian Geier, Barbara Kessler, Eckhard Wolf, Rolf Zeller, Javier Lopez-Rios
Cell Rep. 2020 Apr 7; 31(1): 107490. Published online 2020 Apr 7. doi: 10.1016/j.celrep.2020.03.054
PMCID:
PMC7166081
AbstractArticle
15.
De novo PITX1 expression controls bi-stable transcriptional circuits to govern self-renewal and differentiation in squamous cell carcinoma
Ana Sastre-Perona, Steven Hoang-Phou, Marie-Christin Leitner, Martyna Okuniewska, Shane Meehan, Markus Schober
Cell Stem Cell. Author manuscript; available in PMC 2020 Mar 19.
Published in final edited form as: Cell Stem Cell. 2019 Mar 7; 24(3): 390–404.e8. Published online 2019 Jan 31. doi: 10.1016/j.stem.2019.01.003
PMCID:
PMC7081946
AbstractArticlePDF–3.6M
16.
Isl1 regulation of Nkx2.1 in the early foregut epithelium is required for tracheaesophageal separation and lung lobation
Eugene Kim, Ming Jiang, Huachao Huang, Yongchun Zhang, Natalie Tjota, Xia Gao, Jacques Robert, Nikesha Gilmore, Lin Gan, Jianwen Que
Dev Cell. Author manuscript; available in PMC 2020 Dec 16.
Published in final edited form as: Dev Cell. 2019 Dec 16; 51(6): 675–683.e4. Published online 2019 Dec 5. doi: 10.1016/j.devcel.2019.11.002
PMCID:
PMC6919560
AbstractArticlePDF–2.5M
17.
Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos
Junji Itou, Hiroko Kawakami, Thu Quach, Marco Osterwalder, Sylvia M. Evans, Rolf Zeller, Yasuhiko Kawakami
Development. 2012 May 1; 139(9): 1620–1629. Published online 2012 Apr 3. doi: 10.1242/dev.073056
PMCID:
PMC6514305
AbstractArticle
18.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
19.
Bone-Specific Overexpression of PITX1 Induces Senile Osteoporosis in Mice Through Deficient Self-Renewal of Mesenchymal Progenitors and Wnt Pathway Inhibition
Nancy Karam, Jean-François Lavoie, Benoit St-Jacques, Saadallah Bouhanik, Anita Franco, Nihad Ladoul, Alain Moreau
Sci Rep. 2019; 9: 3544. Published online 2019 Mar 5. doi: 10.1038/s41598-019-40274-6
PMCID:
PMC6401072
AbstractArticlePDF–5.2M
20.
A novel enhancer near the Pitx1 gene influences development and evolution of pelvic appendages in vertebrates
Abbey C Thompson, Terence D Capellini, Catherine A Guenther, Yingguang Frank Chan, Carlos R Infante, Douglas B Menke, David M Kingsley
eLife. 2018; 7: e38555. Published online 2018 Nov 30. doi: 10.7554/eLife.38555
PMCID:
PMC6269122
AbstractArticlePDF–9.5M

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