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Items: 1 to 20 of 30

1.
Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases
Zhan-Li Chen, Chen Xie, Wei Zeng, Rui-Qi Huang, Jin-E Yang, Jin-Yu Liu, Ya-Jing Chen, Shi-Mei Zhuang
Signal Transduct Target Ther. 2024; 9: 181. Published online 2024 Jul 12. doi: 10.1038/s41392-024-01896-z
PMCID:
PMC11239683
AbstractArticlePDF–8.8M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Autophagy modulates the stability of Wee1 and cell cycle G2/M transition
Biwei Han, Yajing Chen, Chen Song, Yali Chen, Yong Chen, Daniel Ferguson, Yunzhi Yang, Anyuan He
Biochem Biophys Res Commun. Author manuscript; available in PMC 2024 Feb 28.
Published in final edited form as: Biochem Biophys Res Commun. 2023 Oct 15; 677: 63–69. Published online 2023 Aug 4. doi: 10.1016/j.bbrc.2023.08.010
PMCID:
PMC10900895
AbstractArticlePDF–1.4M
4.
Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2
Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Violetta Steeples, Amar J. Azad, Evie Singer, Jasmeet S. Reyat, Frantisek Galatik, Elisabeth Ehler, Pauline Bennett, Jacinta I. Kalisch-Smith, Duncan B. Sparrow, Benjamin Davies, Kristina Djinovic-Carugo, Mathias Gautel, Hugh Watkins, Katja Gehmlich
Cells. 2023 Mar; 12(5): 721. Published online 2023 Feb 24. doi: 10.3390/cells12050721
PMCID:
PMC10001372
AbstractArticlePDF–2.7M
5.
Wee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-γH2AX-MDC1
Fanting Zeng, Yuhang Peng, Yuefeng Qin, Jianming Wang, Guoyun Jiang, Wenli Feng, Ying Yuan
Cell Commun Signal. 2022; 20: 199. Published online 2022 Dec 27. doi: 10.1186/s12964-022-01021-z
PMCID:
PMC9793686
AbstractArticlePDF–17M
6.
Heart neurons use clock genes to control myocyte proliferation
Emmanouil Tampakakis, Harshi Gangrade, Stephanie Glavaris, Myo Htet, Sean Murphy, Brian Leei Lin, Ting Liu, Amir Saberi, Matthew Miyamoto, William Kowalski, Yoh-Suke Mukouyama, Gabsang Lee, Liliana Minichiello, Chulan Kwon
Sci Adv. 2021 Dec; 7(49): eabh4181. Published online 2021 Dec 1. doi: 10.1126/sciadv.abh4181
PMCID:
PMC8635446
AbstractArticlePDF–6.2M
7.
WEE1 inhibition induces anti-tumor immunity by activating ERV and the dsRNA pathway
Ensong Guo, Rourou Xiao, Yifan Wu, Funian Lu, Chen Liu, Bin Yang, Xi Li, Yu Fu, Zizhuo Wang, Yuan Li, Yuhan Huang, Fuxia Li, Xue Wu, Lixin You, Tianyu Qin, Yiling Lu, Xiaoyuan Huang, Ding Ma, Gordon B. Mills, Chaoyang Sun, Gang Chen
J Exp Med. 2022 Jan 3; 219(1): e20210789. Published online 2021 Nov 26. doi: 10.1084/jem.20210789
PMCID:
PMC8628262
AbstractArticlePDF–9.7M
8.
WEE1 promotes endometriosis via the Wnt/β-catenin signaling pathway
Liya Shi, Xue Xue, Hui Tian, Hongjuan Ye, Hui Wang, Rongxiang Wang, Yu Liu, Caixia Zhang, Qiuju Chen, Lihua Sun
Reprod Biol Endocrinol. 2021; 19: 161. Published online 2021 Oct 22. doi: 10.1186/s12958-021-00844-8
PMCID:
PMC8532311
AbstractArticlePDF–2.9M
9.
CDC5L promotes early chondrocyte differentiation and proliferation by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE1
Go Jokoji, Shingo Maeda, Kazuki Oishi, Toshiro Ijuin, Masahiro Nakajima, Hiroki Tawaratsumida, Ichiro Kawamura, Hiroyuki Tominaga, Eiji Taketomi, Shiro Ikegawa, Noboru Taniguchi
J Biol Chem. 2021 Aug; 297(2): 100994. Published online 2021 Jul 21. doi: 10.1016/j.jbc.2021.100994
PMCID:
PMC8363834
AbstractArticlePDF–3.4M
10.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
11.
WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis
A Vassilopoulos, Y Tominaga, H-Seok Kim, T Lahusen, B Li, H Yu, D Gius, C-X Deng
Oncogene. Author manuscript; available in PMC 2017 Aug 8.
Published in final edited form as: Oncogene. 2015 Jun 4; 34(23): 3023–3035. Published online 2014 Aug 4. doi: 10.1038/onc.2014.239
PMCID:
PMC5547996
AbstractArticlePDF–853K
12.
Lacking of palladin leads to multiple cellular events changes which contribute to NTD
Juan Tan, Xue-Jiao Chen, Chun-Ling Shen, Hong-Xin Zhang, Ling-Yun Tang, Shun-Yuan Lu, Wen-Ting Wu, Ying Kuang, Jian Fei, Zhu-Gang Wang
Neural Dev. 2017; 12: 4. Published online 2017 Mar 24. doi: 10.1186/s13064-017-0081-6
PMCID:
PMC5366166
AbstractArticlePDF–8.9M
13.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
14.
MicroRNA-219-5p Inhibits Morphine-Induced Apoptosis by Targeting Key Cell Cycle Regulator WEE1
Wei Lou, Xingwang Zhang, Xiao-Ying Hu, Ai-Rong Hu
Med Sci Monit. 2016; 22: 1872–1879. Published online 2016 Jun 2. doi: 10.12659/MSM.895439
PMCID:
PMC4913725
AbstractArticlePDF–986K
15.
Protein tyrosine kinase Wee1B is essential for metaphase II exit in mouse oocytes
Jeong Su Oh, Andrej Susor, Marco Conti
Science. Author manuscript; available in PMC 2014 Jul 21.
Published in final edited form as: Science. 2011 Apr 22; 332(6028): 462–465. Published online 2011 Mar 31. doi: 10.1126/science.1199211
PMCID:
PMC4104668
AbstractArticlePDF–398K
16.
Novel Protein Interactions with Endoglin and Activin Receptor-like Kinase 1: Potential Role in Vascular Networks
Guoxiong Xu, Miriam Barrios-Rodiles, Mirjana Jerkic, Andrei L. Turinsky, Robert Nadon, Sonia Vera, Despina Voulgaraki, Jeffrey L. Wrana, Mourad Toporsian, Michelle Letarte
Mol Cell Proteomics. 2014 Feb; 13(2): 489–502. Published online 2013 Dec 7. doi: 10.1074/mcp.M113.033464
PMCID:
PMC3916649
AbstractArticlePDF–4.1M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
Filamin A Regulates Neural Progenitor Proliferation and Cortical Size through Wee1-Dependent Cdk1 Phosphorylation
Gewei Lian, Jie Lu, Jianjun Hu, Jingping Zhang, Sally H. Cross, Russell J. Ferland, Volney L. Sheen
J Neurosci. 2012 May 30; 32(22): 7672–7684. doi: 10.1523/JNEUROSCI.0894-12.2012
PMCID:
PMC3368379
AbstractArticlePDF–6.0M
19.
Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module
Matthew Koss, Alexandre Bolze, Andrea Brendolan, Matilde Saggese, Terence D. Capellini, Ekaterina Bojilova, Bertrand Boisson, Owen W.J. Prall, David Elliott, Mark Solloway, Elisa Lenti, Chisa Hidaka, Ching-Pin Chang, Nizar Mahlaoui, Richard P. Harvey, Jean-Laurent Casanova, Licia Selleri
Dev Cell. Author manuscript; available in PMC 2013 May 15.
Published in final edited form as: Dev Cell. 2012 May 15; 22(5): 913–926. Published online 2012 May 3. doi: 10.1016/j.devcel.2012.02.009
PMCID:
PMC3356505
AbstractArticlePDF–6.8M
20.
Hypoxia induces Wee1 expression and attenuates hydrogen peroxide-induced endothelial damage in MS1 cells
Ki-Sun Hong, Hyeon-Soo Kim, Se-Hoon Kim, Dong-Jun Lim, Jung-Yul Park, Sang-Dae Kim
Exp Mol Med. 2011 Dec 31; 43(12): 653–659. Published online 2011 Sep 15. doi: 10.3858/emm.2011.43.12.074
PMCID:
PMC3256292
AbstractArticlePDF–600K

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