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Items: 1 to 20 of 30

1.
Tumor-derived KLK8 predicts inferior survival and promotes an immune-suppressive tumor microenvironment in lung squamous cell carcinoma
He Tian, Ran Wei, Chu Xiao, Tao Fan, Yun Che, Tiejun Liu, Bo Zheng, Chunxiang Li, Jie He
BMC Pulm Med. 2024; 24: 53. Published online 2024 Jan 25. doi: 10.1186/s12890-023-02770-4
PMCID:
PMC10809653
AbstractArticlePDF–4.1M
2.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
3.
The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers
Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy
eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676
PMCID:
PMC9708086
AbstractArticlePDF–8.5M
4.
DNA methylation of the KLK8 gene in depression symptomatology
Anna Starnawska, Lina Bukowski, Ana Chernomorchenko, Betina Elfving, Heidi Kaastrup Müller, Edwin van den Oord, Karolina Aberg, Jerry Guintivano, Jakob Grove, Ole Mors, Anders D. Børglum, Anders L. Nielsen, Per Qvist, Nicklas Heine Staunstrup
Clin Epigenetics. 2021; 13: 200. Published online 2021 Oct 29. doi: 10.1186/s13148-021-01184-5
PMCID:
PMC8556955
AbstractArticlePDF–979K
5.
KLK8 promotes the proliferation and metastasis of colorectal cancer via the activation of EMT associated with PAR1
Qing Hua, Zhirong Sun, Yi Liu, Xuefang Shen, Weiwei Zhao, Xiaoyan Zhu, Pingbo Xu
Cell Death Dis. 2021 Oct; 12(10): 860. Published online 2021 Sep 22. doi: 10.1038/s41419-021-04149-x
PMCID:
PMC8458432
AbstractArticlePDF–7.2M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Higher levels of kallikrein‐8 in female brain may increase the risk for Alzheimer's disease
Kathy Keyvani, Yvonne Münster, Nirup K. Kurapati, Sebastian Rubach, Andreas Schönborn, Emre Kocakavuk, Mohamed Karout, Pia Hammesfahr, Ya‐Chao Wang, Dirk M. Hermann, Sarah Teuber‐Hanselmann, Arne Herring
Brain Pathol. 2018 Nov; 28(6): 947–964. Published online 2018 Apr 10. doi: 10.1111/bpa.12599
PMCID:
PMC8028555
AbstractArticlePDF–1.5M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
CSF and blood Kallikrein-8: a promising early biomarker for Alzheimer’s disease
Sarah Teuber-Hanselmann, Jan Rekowski, Jonathan Vogelgsang, Christine von Arnim, Kathrin Reetz, Andreas Stang, Karl-Heinz Jöckel, Jens Wiltfang, Herrmann Esselmann, Markus Otto, Hayrettin Tumani, Arne Herring, Kathy Keyvani
J Neurol Neurosurg Psychiatry. 2020 Jan; 91(1): 40–48. Published online 2019 Aug 1. doi: 10.1136/jnnp-2019-321073
PMCID:
PMC6952834
AbstractArticlePDF–1.5M
10.
Increase of Serum Kallikrein-8 Level After Long-term Telbivudine Treatment
HAW-EN WANG, CHIH-LANG LIN, TAI-LONG PAN, CHAU-TING YEH
In Vivo. 2018 Jul-Aug; 32(4): 955–960. Published online 2018 Jul 3. doi: 10.21873/invivo.112334
PMCID:
PMC6117777
AbstractArticlePDF–174K
11.
Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin
Mekdes Debela, Viktor Magdolen, Wolfgang Skala, Brigitta Elsässer, Eric L. Schneider, Charles S. Craik, Martin L. Biniossek, Oliver Schilling, Wolfram Bode, Hans Brandstetter, Peter Goettig
Sci Rep. 2018; 8: 10705. Published online 2018 Jul 16. doi: 10.1038/s41598-018-29058-6
PMCID:
PMC6048020
AbstractArticlePDF–5.0M
12.
Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 – KLK9), using Next-generation sequencing
Panagiotis G. Adamopoulos, Christos K. Kontos, Andreas Scorilas
Sci Rep. 2017; 7: 17299. Published online 2017 Dec 11. doi: 10.1038/s41598-017-16269-6
PMCID:
PMC5725587
AbstractArticlePDF–4.3M
13.
Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer
Xiaocong Geng, Yueyang Liu, Sandra Diersch, Matthias Kotzsch, Sabine Grill, Wilko Weichert, Marion Kiechle, Viktor Magdolen, Julia Dorn
PLoS One. 2017; 12(11): e0186847. Published online 2017 Nov 2. doi: 10.1371/journal.pone.0186847
PMCID:
PMC5667830
AbstractArticlePDF–2.1M
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
Clinical relevance of kallikrein-related peptidase 6 (KLK6) and 8 (KLK8) mRNA expression in advanced serous ovarian cancer
Nancy Ahmed, Julia Dorn, Rudolf Napieralski, Enken Drecoll, Matthias Kotzsch, Peter Goettig, Eman Zein, Stefanie Avril, Marion Kiechle, Eleftherios P. Diamandis, Manfred Schmitt, Viktor Magdolen
Biol Chem. Author manuscript; available in PMC 2017 Dec 1.
Published in final edited form as: Biol Chem. 2016 Dec 1; 397(12): 1265–1276. doi: 10.1515/hsz-2016-0177
PMCID:
PMC5193116
AbstractArticlePDF–661K
16.
hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes
Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal
Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012
PMCID:
PMC4647941
AbstractArticle
17.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
18.
Prognostic significance of multiple kallikreins in high-grade astrocytoma
Kristen L. Drucker, Caterina Gianinni, Paul A. Decker, Eleftherios P. Diamandis, Isobel A. Scarisbrick
BMC Cancer. 2015; 15: 565. Published online 2015 Aug 1. doi: 10.1186/s12885-015-1566-5
PMCID:
PMC4521496
AbstractArticlePDF–3.7M
19.
Kallikrein-8 Proteolytically Processes Human Papillomaviruses in the Extracellular Space To Facilitate Entry into Host Cells
Carla Cerqueira, Pilar Samperio Ventayol, Christian Vogeley, Mario Schelhaas
J Virol. 2015 Jul 15; 89(14): 7038–7052. Published online 2015 Apr 29. doi: 10.1128/JVI.00234-15
PMCID:
PMC4473586
AbstractArticlePDF–4.2M
20.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M

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