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Select item 114057191.

CMG helicase disassembly is essential and driven by two pathways in budding yeast

Cristian Polo Rivera, Tom D Deegan, Karim P M Labib

EMBO J. 2024 Sep; 43(18): 3818–3845. Published online 2024 Jul 22. doi: 10.1038/s44318-024-00161-x

PMCID:: PMC11405719

Abstract Article PDF–6.9M

Select item 113992612.

Replication licensing regulated by a short linear motif within an intrinsically disordered region of origin recognition complex

Yue Wu, Qiongdan Zhang, Yuhan Lin, Wai Hei Lam, Yuanliang Zhai

Nat Commun. 2024; 15: 8039. Published online 2024 Sep 13. doi: 10.1038/s41467-024-52408-0

PMCID:: PMC11399261

Abstract Article PDF–1.5M

Select item 111168123.

Mitochondria–ER–PM contacts regulate mitochondrial division and PI(4)P distribution

Jason C. Casler, Clare S. Harper, Antoineen J. White, Heidi L. Anderson, Laura L. Lackner

J Cell Biol. 2024 Sep 2; 223(9): e202308144. Published online 2024 May 23. doi: 10.1083/jcb.202308144

PMCID:: PMC11116812

Abstract Article PDF–9.2M

Select item 111048494.

Characterization of the dimeric CMG/pre-initiation complex and its transition into DNA replication forks

Lu Liu, Yue Zhang, Jingjing Zhang, Jian-Hua Wang, Qinhong Cao, Zhen Li, Judith L. Campbell, Meng-Qiu Dong, Huiqiang Lou

Cell Mol Life Sci. 2020 Aug; 77(15): 3041–3058. Published online 2019 Nov 15. doi: 10.1007/s00018-019-03333-9

PMCID:: PMC11104849

Abstract Article PDF–9.1M

Select item 110241855.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108724776.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001387.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106817238.

The N-terminus of Spt16 anchors FACT to MCM2–7 for parental histone recycling

Xuezheng Wang, Yuantao Tang, Jiawei Xu, He Leng, Guojun Shi, Zaifeng Hu, Jiale Wu, Yuwen Xiu, Jianxun Feng, Qing Li

Nucleic Acids Res. 2023 Nov 27; 51(21): 11549–11567. Published online 2023 Oct 18. doi: 10.1093/nar/gkad846

PMCID:: PMC10681723

Abstract Article PDF–6.5M

Select item 105517009.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 1051156110.

Synergism between CMG helicase and leading strand DNA polymerase at replication fork

Zhichun Xu, Jianrong Feng, Daqi Yu, Yunjing Huo, Xiaohui Ma, Wai Hei Lam, Zheng Liu, Xiang David Li, Toyotaka Ishibashi, Shangyu Dang, Yuanliang Zhai

Nat Commun. 2023; 14: 5849. Published online 2023 Sep 20. doi: 10.1038/s41467-023-41506-0

PMCID:: PMC10511561

Abstract Article PDF–5.3M

Select item 1029770011.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 1023508612.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 1010608913.

The conserved histone chaperone Spt6 is strongly required for DNA replication and genome stability

Catherine L.W. Miller, Fred Winston

Cell Rep. Author manuscript; available in PMC 2023 Apr 16.

Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112264. Published online 2023 Mar 15. doi: 10.1016/j.celrep.2023.112264

PMCID:: PMC10106089

Abstract Article PDF–1.3M

Select item 920981114.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 913311215.

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer

Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E. Ivanova, Kathryn M. Stevens, Alex Montoya, S. Sunidhi, Nicolas Lopez Carranza, Marcin J. Skwark, Christian Speck

Nat Commun. 2022; 13: 2915. Published online 2022 May 25. doi: 10.1038/s41467-022-30576-1

PMCID:: PMC9133112

Abstract Article PDF–7.2M

Select item 892711716.

Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase

Jiaxuan Cheng, Ningning Li, Yunjing Huo, Shangyu Dang, Bik-Kwoon Tye, Ning Gao, Yuanliang Zhai

Nat Commun. 2022; 13: 1396. Published online 2022 Mar 16. doi: 10.1038/s41467-022-29070-5

Correction in:: Nat Commun. 2022; 13: 2411.

PMCID:: PMC8927117

Abstract Article PDF–6.6M

Select item 877013117.

Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase

Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley, Alessandro Costa

Nat Struct Mol Biol. 2022; 29(1): 10–20. Published online 2021 Dec 28. doi: 10.1038/s41594-021-00698-z

PMCID:: PMC8770131

Abstract Article PDF–12M

Select item 857106318.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 844326919.

Chromosomal Mcm2-7 distribution and the genome replication program in species from yeast to humans

Eric J. Foss, Smitha Sripathy, Tonibelle Gatbonton-Schwager, Hyunchang Kwak, Adam H. Thiesen, Uyen Lao, Antonio Bedalov

PLoS Genet. 2021 Sep; 17(9): e1009714. Published online 2021 Sep 2. doi: 10.1371/journal.pgen.1009714

PMCID:: PMC8443269

Abstract Article PDF–3.2M

Select item 822535220.

Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28

Elena I Stepchenkova, Anna S Zhuk, Jian Cui, Elena R Tarakhovskaya, Stephanie R Barbari, Polina V Shcherbakova, Dmitrii E Polev, Roman Fedorov, Eugenia Poliakov, Igor B Rogozin, Artem G Lada, Youri I Pavlov

Genetics. 2021 Jun; 218(2): iyab060. Published online 2021 Apr 12. doi: 10.1093/genetics/iyab060