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Select item 114958871.

Structural basis of mitochondrial protein import by the TIM23 complex

Sue Im Sim, Yuanyuan Chen, Diane L. Lynch, James C. Gumbart, Eunyong Park

Nature. Author manuscript; available in PMC 2024 Oct 22.

Published in final edited form as: Nature. 2023 Sep; 621(7979): 620–626. Published online 2023 Jun 21. doi: 10.1038/s41586-023-06239-6

PMCID:: PMC11495887

Article PDF–6.0M

Select item 114465482.

The zinc-finger transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay

Moran Kelbert, Antonio Jordán-Pla, Lola de Miguel-Jiménez, José García-Martínez, Michael Selitrennik, Adi Guterman, Noa Henig, Sander Granneman, José E Pérez-Ortín, Sebastián Chávez, Mordechai Choder

eLife. 2024; 12: RP90766. Published online 2024 Oct 2. doi: 10.7554/eLife.90766

PMCID:: PMC11446548

Article PDF–7.1M

Select item 105202603.

Two domains of Tim50 coordinate translocation of proteins across the two mitochondrial membranes

Marcel G Genge, Shalini Roy Chowdhury, Vít Dohnálek, Kaori Yunoki, Takashi Hirashima, Toshiya Endo, Pavel Doležal, Dejana Mokranjac

Life Sci Alliance. 2023 Dec; 6(12): e202302122. Published online 2023 Sep 25. doi: 10.26508/lsa.202302122

PMCID:: PMC10520260

Article PDF–3.1M

Select item 105113244.

Central role of Tim17 in mitochondrial presequence protein translocation

Laura F. Fielden, Jakob D. Busch, Sandra G. Merkt, Iniyan Ganesan, Conny Steiert, Hanna B. Hasselblatt, Jon V. Busto, Christophe Wirth, Nicole Zufall, Sibylle Jungbluth, Katja Noll, Julia M. Dung, Ludmila Butenko, Karina von der Malsburg, Hans-Georg Koch, Carola Hunte, Martin van der Laan, Nils Wiedemann

Nature. 2023; 621(7979): 627–634. Published online 2023 Aug 1. doi: 10.1038/s41586-023-06477-8

PMCID:: PMC10511324

Article PDF–27M

Select item 92098115.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Article PDF–818K

Select item 84825126.

Aim32 is a dual-localized 2Fe-2S mitochondrial protein that functions in redox quality control

Danyun Zhang, Owen R. Dailey, Daniel J. Simon, Kamilah Roca-Datzer, Yasaman Jami-Alahmadi, Mikayla S. Hennen, James A. Wohlschlegel, Carla M. Koehler, Deepa V. Dabir

J Biol Chem. 2021 Oct; 297(4): 101135. Published online 2021 Aug 28. doi: 10.1016/j.jbc.2021.101135

PMCID:: PMC8482512

Article PDF–5.0M

Select item 84815427.

Mapping protein interactions in the active TOM-TIM23 supercomplex

Ridhima Gomkale, Andreas Linden, Piotr Neumann, Alexander Benjamin Schendzielorz, Stefan Stoldt, Olexandr Dybkov, Markus Kilisch, Christian Schulz, Luis Daniel Cruz-Zaragoza, Blanche Schwappach, Ralf Ficner, Stefan Jakobs, Henning Urlaub, Peter Rehling

Nat Commun. 2021; 12: 5715. Published online 2021 Sep 29. doi: 10.1038/s41467-021-26016-1

PMCID:: PMC8481542

Article PDF–9.2M

Select item 75862328.

The intermembrane space protein Mix23 is a novel stress-induced mitochondrial import factor

Eva Zöller, Janina Laborenz, Lena Krämer, Felix Boos, Markus Räschle, R. Todd Alexander, Johannes M. Herrmann

J Biol Chem. 2020 Oct 23; 295(43): 14686–14697. Published online 2020 Aug 21. doi: 10.1074/jbc.RA120.014247

PMCID:: PMC7586232

Article PDF–2.5M

Select item 73531649.

Mgr2 regulates mitochondrial preprotein import by associating with channel-forming Tim23 subunit

Srujan Kumar Matta, Abhishek Kumar, Patrick D’Silva

Mol Biol Cell. 2020 May 15; 31(11): 1112–1123. doi: 10.1091/mbc.E19-12-0677

PMCID:: PMC7353164

Article PDF–1.6M

Select item 694546210.

The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments

Heike Rampelt, Iva Sucec, Beate Bersch, Patrick Horten, Inge Perschil, Jean-Claude Martinou, Martin van der Laan, Nils Wiedemann, Paul Schanda, Nikolaus Pfanner

BMC Biol. 2020; 18: 2. Published online 2020 Jan 6. doi: 10.1186/s12915-019-0733-6

PMCID:: PMC6945462

Article PDF–4.9M

Select item 651105911.

RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae

Guokun Wang, Sara M. Björk, Mingtao Huang, Quanli Liu, Kate Campbell, Jens Nielsen, Haakan N. Joensson, Dina Petranovic

Proc Natl Acad Sci U S A. 2019 May 7; 116(19): 9324–9332. Published online 2019 Apr 18. doi: 10.1073/pnas.1820561116

PMCID:: PMC6511059

Article PDF–1.6M

Select item 637591712.

A mutagenesis analysis of Tim50, the major receptor of the TIM23 complex, identifies regions that affect its interaction with Tim23

Dana Dayan, May Bandel, Umut Günsel, Inbal Nussbaum, Gali Prag, Dejana Mokranjac, Walter Neupert, Abdussalam Azem

Sci Rep. 2019; 9: 2012. Published online 2019 Feb 14. doi: 10.1038/s41598-018-38353-1

PMCID:: PMC6375917

Article PDF–1.7M

Select item 616856413.

Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane

Alexander Benjamin Schendzielorz, Piotr Bragoszewski, Nataliia Naumenko, Ridhima Gomkale, Christian Schulz, Bernard Guiard, Agnieszka Chacinska, Peter Rehling

Nat Commun. 2018; 9: 4028. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06492-8

PMCID:: PMC6168564

Article PDF–1.4M

Select item 594595014.

Stendomycin selectively inhibits tIM23-dependent mitochondrial protein import

Ireos Filipuzzi, Janos Steffen, Mitchel Germain, Laetitia Goepfert, Michael A Conti, Christoph Potting, Raffaele Cerino, Martin Pfeifer, Philipp Krastel, Dominic Hoepfner, Julie Bastien, Carla M Koehler, Stephen B Helliwell

Nat Chem Biol. Author manuscript; available in PMC 2018 May 11.

Published in final edited form as: Nat Chem Biol. 2017 Dec; 13(12): 1239–1244. Published online 2017 Oct 9. doi: 10.1038/nchembio.2493

PMCID:: PMC5945950

Article PDF–664K

Select item 576535915.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Article PDF–2.2M

Select item 566597716.

INA complex liaises the F₁F_o-ATP synthase membrane motor modules

Nataliia Naumenko, Marcel Morgenstern, Robert Rucktäschel, Bettina Warscheid, Peter Rehling

Nat Commun. 2017; 8: 1237. Published online 2017 Nov 1. doi: 10.1038/s41467-017-01437-z

PMCID:: PMC5665977

Article PDF–1.9M

Select item 566188517.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Article PDF–2.6M

Select item 564803218.

Architecture and dynamics of overlapped RNA regulatory networks

Christopher P. Lapointe, Melanie A. Preston, Daniel Wilinski, Harriet A.J. Saunders, Zachary T. Campbell, Marvin Wickens

RNA. 2017 Nov; 23(11): 1636–1647. doi: 10.1261/rna.062687.117

PMCID:: PMC5648032

Article PDF–6.6M

Select item 555559219.

Homologous PNA Hybridization to Noncanonical DNA G-Quadruplexes

Karen A. Kormuth, John L. Woolford, Jr., Bruce A. Armitage

Biochemistry. Author manuscript; available in PMC 2017 Aug 14.

Published in final edited form as: Biochemistry. 2016 Mar 29; 55(12): 1749–1757. Published online 2016 Mar 16. doi: 10.1021/acs.biochem.6b00026

PMCID:: PMC5555592

Article PDF–1.4M

Select item 542207420.

Dual interaction of scaffold protein Tim44 of mitochondrial import motor with channel-forming translocase subunit Tim23

See-Yeun Ting, Nicholas L Yan, Brenda A Schilke, Elizabeth A Craig

eLife. 2017; 6: e23609. Published online 2017 Apr 25. doi: 10.7554/eLife.23609

PMCID:: PMC5422074

Article PDF–6.7M

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